rotenone has been researched along with Encephalopathy, Toxic in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (13.21) | 29.6817 |
| 2010's | 25 (47.17) | 24.3611 |
| 2020's | 21 (39.62) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Dong, J; Li, Q; Luo, H; Peng, C; Peng, Y; Shi, F; Xu, X | 1 |
| Cunha-Oliveira, T; Oliveira, PJ; Pereira, FB; Simões, RF | 1 |
| Bohara, G; Choi, DY; Choi, H; Ghavami, S; Khanal, S; Kim, G; Sadigh-Eteghad, S; Shadfar, S | 1 |
| Ahmed, HI; Albohy, A; Azab, SS; Kamal, RE; Menze, E | 1 |
| Cao, X; Du, W; Gan, J; Han, B; Han, X; He, J; Li, G; Wang, T; Wang, Z; Zhao, Y; Zheng, W | 1 |
| Anantharam, V; Bargues-Carot, A; Huang, M; Jin, H; Kanthasamy, A; Kanthasamy, AG; Riaz, Z; Wickham, H; Zenitsky, G | 1 |
| Cediel-Ulloa, A; Forsby, A; Gabring, N; Gliga, A; Hinojosa, MG; Ivanova, E; Johansson, Y | 1 |
| Baumann, L; Braunbeck, T; Gade, C; Leist, M; von Hellfeld, R | 1 |
| Anguchamy, V; Muthuvel, A | 1 |
| Cai, X; Cao, P; Chen, B; He, Z; Qin, Y; Shen, J; Wang, Y; Xu, Y; Yang, Y; Ye, J; Zhou, Q | 1 |
| Albalakhi, A; Bakshi, R; Lin, S; Madore, V; Schwarzschild, MA; Stimpson, T; Xia, N; Xu, Y | 1 |
| Chen, C; Hu, AL; Li, H; Liu, J; Zhang, BB; Zhang, F | 1 |
| Mursaleen, L; Somavarapu, S; Zariwala, MG | 1 |
| Joshi, P; Kang, SY; Kothapalli, C; Lee, MY; Yu, KN | 1 |
| Freeman, DM; Li, Y; Lou, D; Martos, SN; Wang, Z | 1 |
| Abdel-Moneim, AM; Abdou, HM; Alfwuaires, M; Essawy, AE; Mohammed, NA; Tass, MA | 1 |
| Bellak, T; Bock, I; Dinnyes, A; Janstova, Z; Kobolak, J; Laszlo, L; Molnar, K; Teglasi, A; Zana, M | 1 |
| Li, DD; Li, JJ; Sheng, S; Wang, GQ; Wei, YZ; Zhang, F; Zheng, CQ; Zhu, GF | 1 |
| Freeman, JL; Wasel, O | 1 |
| Abd El-Fadeal, NM; Abdelbasset, WK; El-Abaseri, TB; El-Saber Batiha, G; El-Sherbeeny, NA; Hashish, AA; Soliman, N; Youssef, AM; Zaitone, SA | 1 |
| Bicker, G; Dempewolf, S; Schmitz, A; Stern, M; Tan, S | 1 |
| Kanninen, KM; White, AR | 1 |
| Chidambaram, R; Dhanalakshmi, C; Essa, MM; Gobi, VV; Justin Thenmozhi, A; Kalandar, A; Manivasagam, T; Rajasankar, S; Ramkumar, M | 1 |
| Cao, X; Kuang, L; Lu, Z | 1 |
| Biswas, J; Gupta, P; Gupta, S; Singh, A; Singh, DK; Singh, S; Verma, DK | 1 |
| Barreras, P; Block, K; Gribaldo, L; Harris, G; Hartung, T; Hogberg, HT; Lau, P; Pamies, D; Pardo, CA; Smirnova, L; Wiersma, D; Zhao, L | 1 |
| Krishna, G | 1 |
| Costa, SL; da Silva, VDA; Fonseca-Fonseca, LA; Montano-Peguero, Y; Núñez-Figueredo, Y; Padrón Yaquis, AS; Pardo-Andreu, GL; Ramírez-Sánchez, J; Rodríguez, AM; Wong-Guerra, M | 1 |
| Bhurtel, S; Choi, DY; Choi, H; Hong, JT; Katila, N; Maharjan, S; Neupane, S; Srivastav, S | 1 |
| Fu, X; Klaunig, JE; Lu, Y; Shi, J; Wang, X; Wu, Q; Zeng, R; Zhou, Q; Zhou, S | 1 |
| Cai, Z; Fan, LW; Kaizaki, A; Lin, RC; Lin, S; Ma, T; Pang, Y; Simpson, KL; Tien, LT | 1 |
| Balmer, NV; Krug, AK; Leist, M; Matt, F; Merhof, D; Schönenberger, F | 1 |
| Chen, NH; Gao, K; Han, N; Ma, KL; Song, LK; Yuan, YH; Zhang, Y | 1 |
| Gokul, K | 1 |
| Jang, W; Jo, KD; Kim, HJ; Lee, MK; Li, H; Song, SH; Yang, HO | 1 |
| Chang, C; Gao, B; Gao, G; Li, C; Wang, C; Zhao, T; Zhou, J | 1 |
| Cai, X; Cao, P; Chen, B; Chen, J; Cheng, X; Hu, Z; Lu, W; Shen, J; Sun, X; Wang, X; Wu, L; Yan, H; Yang, J; Yang, Y; Ye, J; Zhou, Q | 1 |
| Brody, KM; Crack, PJ; Kirby, FJ; Main, BS; Taylor, JM; Zhang, M | 1 |
| Alam, M; Danysz, W; Dekundy, A; Schmidt, WJ | 1 |
| Calvez, M; Chesneau, P; De Haro, L; Hayek-Lanthois, M; Joubert, M; Knibiehly, M; Tichadou, L | 1 |
| Hosamani, R | 1 |
| Jankovic, J; Le, W; Li, X; Pan, T; Wu, Y; Xie, W | 1 |
| Cannon, JR; Greenamyre, JT | 1 |
| Colosio, C; Moretto, A | 1 |
| Hineno, A; Ikeda, S; Kaneko, K; Yoshida, K | 1 |
| Cuenca, N; De Juan, E; Esteve-Rudd, J; Fernández-Sánchez, L; Lax, P; Martín-Nieto, J | 1 |
| ElDakroory, SAE; Elghaffar, HA; ElHak, SG; Elhusseiny, M; ElTantawy, D; Ghanem, AA; Salama, M | 1 |
| Goswami, P; Kamat, PK; Nath, C; Patro, IK; Singh, S; Swarnkar, S | 1 |
| El-Gamal, A; El-Gamal, M; Ellaithy, A; Helmy, B; Mohamed, M; Reda, A; Salama, M; Sheashaa, H; Sobh, M; Tantawy, D | 1 |
| Bloomquist, JR; Klorig, DC; Kou, J | 1 |
| Fricke, ST; Hailu, A; Moussa, CE; Rusnak, M; Sidhu, A | 1 |
| An, LJ; Bao, YM; Jiang, B; Liu, YM | 1 |
| Aschner, M; Seegal, RF | 1 |
4 review(s) available for rotenone and Encephalopathy, Toxic
| Article | Year |
|---|---|
Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson's Disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; DDT; Dieldrin; Herbicides; Humans; Manganese; Mitochondria; Neuroinflammatory Diseases; Neurotoxicity Syndromes; Oxidative Stress; Paraquat; Parkinson Disease; Pesticides; Risk Factors; Rotenone; Trichloroethanes; Vanadium | 2022 |
Chemical and Genetic Zebrafish Models to Define Mechanisms of and Treatments for Dopaminergic Neurodegeneration.
Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Gene Knockdown Techniques; Neurotoxicity Syndromes; Oxidopamine; Paraquat; Parkinson Disease; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone; Zebrafish; Zebrafish Proteins | 2020 |
Neurotoxic in vivo models of Parkinson's disease recent advances.
Topics: Animals; Disease Models, Animal; Dopamine; Humans; MPTP Poisoning; Neurotoxicity Syndromes; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Rotenone; Sympatholytics; Uncoupling Agents | 2010 |
Biochemical and toxicological evidence of neurological effects of pesticides: the example of Parkinson's disease.
Topics: Animals; Brain; Dieldrin; Dose-Response Relationship, Drug; Humans; Maneb; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Pesticides; Pyrethrins; Risk Assessment; Risk Factors; Rotenone; Time Factors; Toxicity Tests | 2011 |
49 other study(ies) available for rotenone and Encephalopathy, Toxic
| Article | Year |
|---|---|
The Protective Effects of Mogroside V Against Neuronal Damages by Attenuating Mitochondrial Dysfunction via Upregulating Sirtuin3.
Topics: Antioxidants; Dopaminergic Neurons; Humans; Mitochondria; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; Rotenone; Sirtuin 3; Triterpenes | 2022 |
Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics.
Topics: Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidopamine; Rotenone | 2022 |
Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone-Induced Neurotoxicity.
Topics: alpha-Synuclein; AMP-Activated Protein Kinases; Animals; Boswellia; Dopamine; Dopaminergic Neurons; Mammals; Methanol; Mice; Neuroprotective Agents; Neurotoxicity Syndromes; Plant Extracts; Rotenone | 2022 |
Neuroprotective repositioning and anti-tau effect of carvedilol on rotenone induced neurotoxicity in rats: Insights from an insilico& in vivo anti-Parkinson's disease study.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carvedilol; Glial Fibrillary Acidic Protein; Glycogen Synthase; Glycogen Synthase Kinase 3 beta; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Rats; Receptors, N-Methyl-D-Aspartate; Rotenone; Tyrosine 3-Monooxygenase | 2022 |
Rosmarinic Acid Attenuates Rotenone-Induced Neurotoxicity in SH-SY5Y Parkinson's Disease Cell Model through Abl Inhibition.
Topics: Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Cell Survival; Cinnamates; Depsides; Humans; Neuroblastoma; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Reactive Oxygen Species; Rosmarinic Acid; Rotenone | 2022 |
Evaluation of mRNA markers in differentiating human SH-SY5Y cells for estimation of developmental neurotoxicity.
Topics: Animals; Cell Differentiation; Humans; Methylmercury Compounds; Neuroblastoma; Neurons; Neurotoxicity Syndromes; RNA, Messenger; Rotenone | 2023 |
The sensitivity of the zebrafish embryo coiling assay for the detection of neurotoxicity by compounds with diverse modes of action.
Topics: Acrylamides; Animals; Carbaryl; Embryo, Nonmammalian; Hexachlorophene; Ibuprofen; Neurotoxicity Syndromes; Rotenone; Water Pollutants, Chemical; Zebrafish | 2023 |
Enhancing the neuroprotective effect of squid outer skin astaxanthin against rotenone-induced neurotoxicity in in-vitro model for Parkinson's disease.
Topics: Animals; Antioxidants; Decapodiformes; Humans; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Rotenone | 2023 |
Geniposide protects against neurotoxicity in mouse models of rotenone-induced Parkinson's disease involving the mTOR and Nrf2 pathways.
Topics: Animals; Chromatography, Liquid; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Oxidative Stress; Parkinson Disease; Rotenone; Tandem Mass Spectrometry; TOR Serine-Threonine Kinases | 2024 |
Microglia-dependent neuroprotective effects of 4-octyl itaconate against rotenone-and MPP+-induced neurotoxicity in Parkinson's disease.
Topics: Animals; Mice; Microglia; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Parkinson Disease; Rotenone | 2023 |
Protective role of cinnabar and realgar in Hua-Feng-Dan against LPS plus rotenone-induced neurotoxicity and disturbance of gut microbiota in rats.
Topics: Animals; Arsenicals; Disease Models, Animal; DNA, Bacterial; Dopaminergic Neurons; Drugs, Chinese Herbal; Enterobacteriaceae; Ethnopharmacology; Gastrointestinal Microbiome; Humans; Inflammation Mediators; Lactobacillaceae; Lipopolysaccharides; Male; Mercury Compounds; Microglia; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; RNA, Ribosomal, 16S; Rotenone; Sulfides; Verrucomicrobia | 2020 |
Deferoxamine and Curcumin Loaded Nanocarriers Protect Against Rotenone-Induced Neurotoxicity.
Topics: Antioxidants; Cell Line, Tumor; Curcumin; Deferoxamine; Humans; Iron Chelating Agents; Lipid Peroxidation; Nanotechnology; Neurotoxicity Syndromes; Oxidative Stress; Parkinson Disease; Rotenone | 2020 |
High-content imaging of 3D-cultured neural stem cells on a 384-pillar plate for the assessment of cytotoxicity.
Topics: 4-Aminopyridine; Apoptosis; Cell Culture Techniques; Cell Line; Cell Survival; Digoxin; DNA Damage; High-Throughput Screening Assays; Humans; Membrane Potential, Mitochondrial; Neural Stem Cells; Neurotoxicity Syndromes; Rotenone; Topotecan | 2020 |
The conserved DNMT1-dependent methylation regions in human cells are vulnerable to neurotoxicant rotenone exposure.
Topics: Animals; Conserved Sequence; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenome; HEK293 Cells; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Insecticides; Mice; Neurofilament Proteins; Neurotoxicity Syndromes; Potassium Channels; Rotenone; Transcriptome | 2020 |
Oral Supplements of
Topics: Administration, Oral; Animals; Antioxidants; Brain; Cytokines; Dietary Supplements; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Ginkgo biloba; Glutathione; Lipid Peroxidation; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Parkinson Disease; Plant Extracts; Random Allocation; Rats; Rotenone; Superoxide Dismutase | 2020 |
Human Induced Pluripotent Stem Cell-Derived 3D-Neurospheres are Suitable for Neurotoxicity Screening.
Topics: Biomarkers; Cell Death; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Female; Humans; Induced Pluripotent Stem Cells; Middle Aged; Mitochondria; Models, Biological; Neural Stem Cells; Neuronal Outgrowth; Neurons; Neurotoxicity Syndromes; Rotenone; Spheroids, Cellular | 2020 |
Ellagic acid protects dopamine neurons from rotenone-induced neurotoxicity via activation of Nrf2 signalling.
Topics: Animals; Antioxidants; Dopaminergic Neurons; Ellagic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Oxidative Stress; Rotenone | 2020 |
The protective effect of biochanin A against rotenone-induced neurotoxicity in mice involves enhancing of PI3K/Akt/mTOR signaling and beclin-1 production.
Topics: Animals; Autophagy; Beclin-1; Cytokines; Dopaminergic Neurons; Genistein; Glutathione; Insecticides; Male; Mice; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rotenone; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
Developmental Neurotoxicity of Fipronil and Rotenone on a Human Neuronal In Vitro Test System.
Topics: Cell Differentiation; Cell Line; Cell Movement; Dose-Response Relationship, Drug; Humans; Insecticides; Neuronal Outgrowth; Neurons; Neurotoxicity Syndromes; Pyrazoles; Rotenone | 2021 |
Type-I interferons in Parkinson's disease: innate inflammatory response drives fate of neurons in model of degenerative brain disorder: An editorial comment on 'Type-I interferons mediate the neuroinflammatory response and neurotoxicity induced by rotenon
Topics: Humans; Interferon Type I; Neurons; Neurotoxicity Syndromes; Parkinson Disease; Rotenone | 2017 |
Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cells.
Topics: Cell Death; Cell Line, Tumor; Cell Survival; Curcuma; Curcumin; Cytochromes c; Diarylheptanoids; Dopaminergic Neurons; Humans; Insecticides; Membrane Potential, Mitochondrial; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Parkinson Disease; Phytotherapy; Plant Extracts; Reactive Oxygen Species; Rotenone | 2017 |
Baicalein Protects against Rotenone-Induced Neurotoxicity through Induction of Autophagy.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dopamine; Flavanones; Homeostasis; Humans; Insecticides; Male; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Phytotherapy; Plant Extracts; Reactive Oxygen Species; Rotenone; Scutellaria baicalensis | 2017 |
Minocycline diminishes the rotenone induced neurotoxicity and glial activation via suppression of apoptosis, nitrite levels and oxidative stress.
Topics: Animals; Apoptosis; Astrocytes; Brain; Caspase 3; CD11b Antigen; DNA Fragmentation; Glutathione; Lipid Peroxidation; Male; Microglia; Microtubule-Associated Proteins; Minocycline; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrites; Oxidative Stress; Rats; Rotenone; Stress, Physiological | 2018 |
Rotenone exerts developmental neurotoxicity in a human brain spheroid model.
Topics: Age Factors; Brain; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Developmental; Humans; Induced Pluripotent Stem Cells; Insecticides; Metabolomics; Mitochondria; Neural Stem Cells; Neurogenesis; Neuroglia; Neurotoxicity Syndromes; Oxidative Stress; Reactive Oxygen Species; Risk Assessment; Rotenone; Spheroids, Cellular; Time Factors; Toxicity Tests | 2018 |
Oral supplements of inulin during gestation offsets rotenone-induced oxidative impairments and neurotoxicity in maternal and prenatal rat brain.
Topics: Animals; Biomarkers; Brain; Dietary Supplements; Female; Inulin; Lipid Peroxidation; Male; Mitochondria; Neurotoxicity Syndromes; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Rotenone | 2018 |
JM-20, a novel hybrid molecule, protects against rotenone-induced neurotoxicity in experimental model of Parkinson's disease.
Topics: Animals; Benzodiazepines; Body Weight; Brain; Catalase; Cell Death; Cells, Cultured; Humans; Male; Mitochondria; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Niacin; Oxidative Stress; Rats; Rotenone; Superoxide Dismutase | 2019 |
Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity.
Topics: Acetylation; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Butyrates; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Glial Cell Line-Derived Neurotrophic Factor; Histones; Male; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Neuroglia; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Probiotics; Rotenone | 2019 |
Icariin protects rotenone-induced neurotoxicity through induction of SIRT3.
Topics: Animals; Blotting, Western; Dopaminergic Neurons; Flavonoids; Glucosides; Glutathione; Glutathione Disulfide; Male; Mitochondria; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Oxygen Consumption; PC12 Cells; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rotarod Performance Test; Rotenone; Sirtuins; Superoxide Dismutase | 2019 |
Neonatal systemic exposure to lipopolysaccharide enhances susceptibility of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life.
Topics: Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Brain; Cell Count; Dopaminergic Neurons; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation; Lipopolysaccharides; Male; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Rotenone; Uncoupling Agents | 2013 |
Evaluation of a human neurite growth assay as specific screen for developmental neurotoxicants.
Topics: Algorithms; Cell Nucleus; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Interactions; Humans; Indicators and Reagents; Microtubules; Neural Stem Cells; Neurites; Neurotoxicity Syndromes; Neurotoxins; Oxazines; Rotenone; Toxicity Tests; Uncoupling Agents; Xanthenes | 2013 |
The nuclear accumulation of alpha-synuclein is mediated by importin alpha and promotes neurotoxicity by accelerating the cell cycle.
Topics: Active Transport, Cell Nucleus; alpha Karyopherins; alpha-Synuclein; Animals; Behavior, Animal; Cell Cycle; Cell Nucleus; Dopaminergic Neurons; Glucose; Mice, Inbred C57BL; Neurotoxicity Syndromes; PC12 Cells; Radionuclide Imaging; Rats; Recombinant Fusion Proteins; Rotenone; Substantia Nigra; Transfection; Uncoupling Agents | 2014 |
Oral supplements of aqueous extract of tomato seeds alleviate motor abnormality, oxidative impairments and neurotoxicity induced by rotenone in mice: relevance to Parkinson's disease.
Topics: Administration, Oral; Animals; Antioxidants; Male; Mice; Motor Skills Disorders; Neurotoxicity Syndromes; Oxidative Stress; Parkinson Disease; Plant Extracts; Rotenone; Seeds; Solanum lycopersicum; Water | 2014 |
1,25-Dyhydroxyvitamin D₃ attenuates rotenone-induced neurotoxicity in SH-SY5Y cells through induction of autophagy.
Topics: AMP-Activated Protein Kinases; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Beclin-1; Calcitriol; Caspase 3; Cell Line; Dose-Response Relationship, Drug; Humans; Membrane Proteins; Microtubule-Associated Proteins; Neurotoxicity Syndromes; Parkinson Disease; Protective Agents; Reactive Oxygen Species; Rotenone | 2014 |
Pycnogenol Protects Against Rotenone-Induced Neurotoxicity in PC12 Cells Through Regulating NF-κB-iNOS Signaling Pathway.
Topics: Animals; Apoptosis; Cell Survival; Dose-Response Relationship, Drug; Flavonoids; Neurotoxicity Syndromes; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; PC12 Cells; Plant Extracts; Protective Agents; Rats; Rotenone; Signal Transduction | 2015 |
Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways.
Topics: Animals; Autophagy; Cell Line; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Humans; Isothiocyanates; Male; Mice, Inbred BALB C; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Parkinson Disease; Rotenone; Sulfoxides; TOR Serine-Threonine Kinases | 2016 |
Type-I interferons mediate the neuroinflammatory response and neurotoxicity induced by rotenone.
Topics: Animals; Antibodies, Monoclonal; Cell Survival; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Female; Immunity, Innate; Inflammation; Inflammation Mediators; Interferon Type I; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxicity Syndromes; Pregnancy; Rotenone | 2017 |
Effects of glutamate and alpha2-noradrenergic receptor antagonists on the development of neurotoxicity produced by chronic rotenone in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Basal Ganglia; Behavior, Animal; Catalepsy; Cyclopentanes; Disease Models, Animal; Dopamine; Excitatory Amino Acid Antagonists; Hypokinesia; Idazoxan; Male; Motor Activity; Muscle Rigidity; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinsonian Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Adrenergic, alpha-2; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Rotenone; Serotonin; Substantia Nigra; Time Factors | 2009 |
Suicide attempt by ingestion of rotenone-containing plant extracts: one case report in French Guiana.
Topics: Acute Disease; Aged, 80 and over; Fabaceae; Female; French Guiana; Humans; Neurotoxicity Syndromes; Plant Extracts; Rotenone; Suicide, Attempted; Treatment Outcome | 2009 |
Neuroprotective efficacy of Bacopa monnieri against rotenone induced oxidative stress and neurotoxicity in Drosophila melanogaster.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Bacopa; Butyrylcholinesterase; Catalase; Disease Models, Animal; Drosophila melanogaster; Glutathione Transferase; Insecticides; Lipid Peroxides; Male; Malondialdehyde; Neurotoxicity Syndromes; Oxidative Stress; Plant Extracts; Protein Carbonylation; Rotenone; Superoxide Dismutase; Time Factors | 2009 |
Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells.
Topics: Antidotes; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Blotting, Western; Cell Line; Deferoxamine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Membrane Proteins; Neuroprotective Agents; Neurotoxicity Syndromes; Rotenone; Uncoupling Agents | 2010 |
Ceruloplasmin protects against rotenone-induced oxidative stress and neurotoxicity.
Topics: Aldehydes; Animals; Antioxidants; Behavior, Animal; Ceruloplasmin; Electron Transport Complex I; Mice; Mice, Inbred C57BL; Motor Activity; Neurotoxicity Syndromes; Oxidative Stress; Rotenone | 2011 |
Rotenone induces degeneration of photoreceptors and impairs the dopaminergic system in the rat retina.
Topics: Amacrine Cells; Animals; Blotting, Western; Body Weight; Dopaminergic Neurons; Electroretinography; Immunohistochemistry; Mitochondria; Nerve Degeneration; Neurotoxicity Syndromes; Photoreceptor Cells; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Synapses; Uncoupling Agents | 2011 |
Regenerative effects of umbilical cord matrix cells (UCMCs) in a rodent model of rotenone neurotoxicity.
Topics: Animals; Behavior, Animal; Catalepsy; Cell Transplantation; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Neurons; Neurotoxicity Syndromes; Parkinson Disease; Pesticides; Rotenone; Substantia Nigra; Tremor; Tyrosine 3-Monooxygenase; Umbilical Cord | 2012 |
Rotenone-induced neurotoxicity in rat brain areas: a study on neuronal and neuronal supportive cells.
Topics: Analysis of Variance; Animals; Brain; Calcium-Binding Proteins; Caspase 3; CD11b Antigen; CD11c Antigen; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Insecticides; Male; Microfilament Proteins; Neuroglia; Neurons; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rotenone; Tyrosine 3-Monooxygenase | 2013 |
Role of L-thyroxin in counteracting rotenone induced neurotoxicity in rats.
Topics: Animals; Catalepsy; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Microglia; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Thyroxine; Tremor; Tyrosine 3-Monooxygenase | 2013 |
Potentiating effect of the ATP-sensitive potassium channel blocker glibenclamide on complex I inhibitor neurotoxicity in vitro and in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Blotting, Western; Calcium; Cobalt; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Electron Transport Complex I; Glyburide; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Neurotoxicity Syndromes; Potassium Channel Blockers; Rotenone; Tyrosine 3-Monooxygenase | 2006 |
Alterations of striatal glutamate transmission in rotenone-treated mice: MRI/MRS in vivo studies.
Topics: Animals; Brain; Cell Death; Citric Acid Cycle; Energy Metabolism; Feedback; Glutamic Acid; Immunohistochemistry; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neurotoxicity Syndromes; Oxidative Phosphorylation; Rotenone; Synaptic Transmission; Tyrosine 3-Monooxygenase; Uncoupling Agents | 2008 |
Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspase 3; Cell Nucleus; Cell Survival; Dopamine; Flow Cytometry; Genes, bcl-2; Glutathione; Hydroxybenzoates; Membrane Potentials; Mitochondria; Necrosis; Neurotoxicity Syndromes; PC12 Cells; Rats; Reactive Oxygen Species; Rotenone; Uncoupling Agents | 2008 |
Selected presentations and general discussion: session IX summary and research needs.
Topics: Animals; Dopamine; Humans; Neurotoxicity Syndromes; Parkinson Disease; Parkinson Disease, Secondary; Polychlorinated Biphenyls; Rotenone; Saimiri; Thiocarbamates; Uncoupling Agents | 2001 |