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rotenone and Electron Transport Chain Deficiencies, Mitochondrial

rotenone has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (44.00)29.6817
2010's9 (36.00)24.3611
2020's5 (20.00)2.80

Authors

AuthorsStudies
Adant, I; Bird, M; Cassiman, D; de Witte, P; Decru, B; Ghesquière, B; Rymen, D; Vermeersch, P; Wallays, M; Windmolders, P; Witters, P1
Chakraborty, S; Dey, P; Dutta, S; Mukherjee, P; Sarkar, A; Sur, M1
Cui, XS; Nie, ZW; Niu, YJ; Shin, KT; Zhou, W1
Goto, S; Karube, Y; Koga, M; Matsunaga, K; Murata, A; Setoguchi, S; Takata, J; Terada, K; Toki, E; Watase, D; Yamakawa, H1
Bhurtel, S; Choi, DY; Katila, N; Park, PH1
Bénit, P; Diogo, CV; Fernández-Mosquera, L; Lopez, LC; Luna Sánchez, M; Milosevic, I; Raimundo, N; Rustin, P; Santos, GL; Yambire, KF1
He, D; Lei, L; Liu, M; Lou, D; Lu, S; Shi, Y; Song, Y; Wang, Z; Wu, S1
Eiroa, HD; García Samartino, C; Loos, MA; Lubieniecki, F; Marzese, DM; Mayorga, L; Romano, PS; Roqué, M; Salassa, BN1
Black, JA; Estacion, M; Kim, I; Persson, AK; Waxman, SG; Zhao, P1
Cannon, JR; Greenamyre, JT; Tapias, V1
Feng, Z; Hao, J; Jia, H; Li, X; Liu, J; Liu, Z; Shen, W; Zhang, H1
Hayashi, Y; Ide, T; Kang, D; Kanki, T; Nakanishi, H; Ochi-Shindou, M; Sunagawa, K; Tsutsui, H; Wu, Z; Yamato, M; Yoshida, M1
Abou-Sleiman, P; Bandmann, O; Cookson, MR; Klaffke, S; Koopman, WJ; Mortiboys, H; Olpin, S; Smeitink, JA; Thomas, KJ; Willems, PH; Wood, NW1
Chomova, M; Dobrota, D; Hatok, J; Kaplan, P; Racay, P; Tatarkova, Z1
Daniels, WM; Hattingh, S; Pienaar, IS; Schallert, T1
Dieteren, CE; Koopman, WJ; Nijtmans, LG; Roestenberg, P; Smeitink, JA; Valsecchi, F; Willems, PH1
Arnold, B; Berman, SB; Cassady, SJ; VanLaar, VS1
Kabiraj, P; Miranda, M; Narayan, M; Pal, R; Varela-Ramirez, A1
Bottoni, P; Giardina, B; Martorana, GE; Scatena, R1
Leshem, D; Shainberg, A; Shmist, Y; Shneyvays, V; Zinman, T1
Aquilano, K; Ciriolo, MR; Rotilio, G; Vigilanza, P1
Koopman, WJ; Nijtmans, LG; Smeitink, JA; van Emst-de Vries, S; Verkaart, S; Visch, HJ; Willems, PH1
Cheek, J; Koopman, WJ; Smeitink, JA; van den Heuvel, LW; van Emst-de Vries, SE; Verkaart, S; Willems, PH1
Milbrandt, J; Press, C1
Gonzalez-Lima, F; Jones, D; Zhang, X1

Reviews

3 review(s) available for rotenone and Electron Transport Chain Deficiencies, Mitochondrial

ArticleYear
Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation.
    Antioxidants & redox signaling, 2010, Jun-15, Volume: 12, Issue:12

    Topics: Animals; Biological Transport; Cattle; Chromans; Electron Transport; Electron Transport Complex I; Eukaryotic Cells; Fibroblasts; Humans; Mammals; Membrane Lipids; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; NADH Dehydrogenase; Organ Specificity; Oxidative Phosphorylation; Reactive Oxygen Species; Rotenone; Signal Transduction

2010
Mitochondrial dysfunction by synthetic ligands of peroxisome proliferator activated receptors (PPARs).
    IUBMB life, 2004, Volume: 56, Issue:8

    Topics: Animals; Humans; Hypoglycemic Agents; Ligands; Lipid Metabolism; Liver; Mitochondria; Mitochondrial Diseases; Models, Biological; Neoplasms; PPAR alpha; PPAR gamma; Protein Binding; Rotenone; Thiazolidinediones

2004
Human NADH:ubiquinone oxidoreductase deficiency: radical changes in mitochondrial morphology?
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:1

    Topics: Cell Line; Child; Cluster Analysis; Electron Transport Complex I; Electrophoresis; Enzyme Inhibitors; Fibroblasts; Genetic Predisposition to Disease; Humans; Membrane Potential, Mitochondrial; Microscopy, Confocal; Microscopy, Video; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Mitochondrial Size; Mutation; Oxidative Phosphorylation; Reactive Oxygen Species; Reproducibility of Results; Rotenone; Severity of Illness Index; Uncoupling Agents

2007

Other Studies

22 other study(ies) available for rotenone and Electron Transport Chain Deficiencies, Mitochondrial

ArticleYear
Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction.
    Molecular metabolism, 2022, Volume: 63

    Topics: Animals; Metabolome; Mitochondrial Diseases; NAD; Oxidative Phosphorylation; Pyruvic Acid; Rotenone; Uridine; Zebrafish

2022
Early loss of endogenous NAD
    The FEBS journal, 2023, Volume: 290, Issue:6

    Topics: Animals; Armadillo Domain Proteins; Drosophila melanogaster; Mitochondria; Mitochondrial Diseases; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Rotenone

2023
Melatonin enhances mitochondrial biogenesis and protects against rotenone-induced mitochondrial deficiency in early porcine embryos.
    Journal of pineal research, 2020, Volume: 68, Issue:2

    Topics: Animals; Embryo, Mammalian; Embryonic Development; Melatonin; Mitochondria; Mitochondrial Diseases; Rotenone; Swine

2020
Atypical Antipsychotic Drug Ziprasidone Protects against Rotenone-Induced Neurotoxicity: An In Vitro Study.
    Molecules (Basel, Switzerland), 2020, Sep-14, Volume: 25, Issue:18

    Topics: Animals; Antioxidants; Antipsychotic Agents; Apoptosis; Cell Death; Cell Nucleus; Cell Survival; Cytoplasm; Mice; Mitochondrial Diseases; Nerve Growth Factor; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; PC12 Cells; Piperazines; Rats; Reactive Oxygen Species; Receptor, Serotonin, 5-HT1A; Rotenone; Thiazoles

2020
Metformin attenuates rotenone-induced oxidative stress and mitochondrial damage via the AKT/Nrf2 pathway.
    Neurochemistry international, 2021, Volume: 148

    Topics: Cell Line; Cell Survival; Humans; Hypoglycemic Agents; Metformin; Mitochondrial Diseases; NF-E2-Related Factor 2; Oncogene Protein v-akt; Oxidative Stress; Reactive Oxygen Species; Rotenone; Signal Transduction; Uncoupling Agents

2021
Acute and chronic mitochondrial respiratory chain deficiency differentially regulate lysosomal biogenesis.
    Scientific reports, 2017, 03-27, Volume: 7

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Electron Transport; HeLa Cells; Humans; Lysosomes; Mice; Mice, Inbred C57BL; Microphthalmia-Associated Transcription Factor; Mitochondria; Mitochondrial Diseases; Organelle Biogenesis; Protein Kinases; Rotenone; Uncoupling Agents

2017
Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism.
    Experimental neurology, 2018, Volume: 309

    Topics: Adenosine Triphosphate; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Green Fluorescent Proteins; Membrane Potential, Mitochondrial; Membrane Proteins; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Movement; Mutation; Paraquat; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone

2018
Mitochondrial stress triggers a pro-survival response through epigenetic modifications of nuclear DNA.
    Cellular and molecular life sciences : CMLS, 2019, Volume: 76, Issue:7

    Topics: Adolescent; Autophagy; Case-Control Studies; Cell Nucleus; Cell Shape; Cell Survival; Cells, Cultured; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Mitochondria; Mitochondrial Diseases; Myoblasts; Rotenone

2019
Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Dec-04, Volume: 33, Issue:49

    Topics: Animals; Axons; Axotomy; Cell Death; Cells, Cultured; Ganglia, Spinal; Humans; Hydrogen Peroxide; Immunohistochemistry; Mice; Mice, Transgenic; Microtubules; Mitochondrial Diseases; Nerve Degeneration; Neurites; Oxidants; Rotenone; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin; Thiourea; Uncoupling Agents

2013
Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson's disease.
    Neurobiology of aging, 2014, Volume: 35, Issue:5

    Topics: Animals; Caspase 3; Disease Models, Animal; Dopaminergic Neurons; Inflammation; Lythraceae; Male; Mitochondrial Diseases; Nitric Oxide Synthase Type II; Oxidative Stress; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Tyrosine

2014
Synergistic anti-Parkinsonism activity of high doses of B vitamins in a chronic cellular model.
    Neurobiology of aging, 2010, Volume: 31, Issue:4

    Topics: alpha-Synuclein; Biomarkers; Cell Line, Tumor; Coenzymes; DNA Damage; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Electron Transport Complex I; Heat-Shock Proteins; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Models, Biological; Nerve Tissue Proteins; Oxidative Stress; Oxygen Consumption; Parkinson Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Rotenone; Transcription Factors; Ubiquitin; Uncoupling Agents; Vitamin B Complex

2010
Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Aug-20, Volume: 28, Issue:34

    Topics: Aging; Animals; Biological Transport; Brain; DNA Damage; DNA-Binding Proteins; DNA, Mitochondrial; HeLa Cells; Hippocampus; Humans; Intracellular Membranes; Learning; Long-Term Potentiation; Memory; Memory Disorders; Mice; Mice, Transgenic; Microglia; Mitochondrial Diseases; Mitochondrial Proteins; Motor Activity; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Recovery of Function; Rotenone; Transcription Factors; Up-Regulation

2008
Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts.
    Annals of neurology, 2008, Volume: 64, Issue:5

    Topics: Adenosine Triphosphate; Adult; Cells, Cultured; Down-Regulation; Drug Evaluation, Preclinical; Electron Transport Chain Complex Proteins; Energy Metabolism; Fibroblasts; Humans; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Mitochondrial Diseases; Mutation; Neuroprotective Agents; Parkinsonian Disorders; Rotenone; Ubiquitin-Protein Ligases; Uncoupling Agents

2008
Mitochondrial calcium transport and mitochondrial dysfunction after global brain ischemia in rat hippocampus.
    Neurochemical research, 2009, Volume: 34, Issue:8

    Topics: Adaptor Protein Complex 1; Adaptor Protein Complex 4; Animals; Azides; Brain Ischemia; Calcium; Ferricyanides; Hippocampus; Male; Membrane Potentials; Membrane Proteins; Mitochondria; Mitochondrial Diseases; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Rotenone; Spectrometry, Fluorescence; Ubiquinone; Uncoupling Agents

2009
Behavioral and quantitative mitochondrial proteome analyses of the effects of simvastatin: implications for models of neural degeneration.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:7

    Topics: Animals; Disease Models, Animal; Electron Transport Chain Complex Proteins; Free Radicals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mass Spectrometry; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Recovery of Function; Rotenone; Simvastatin; Substantia Nigra; Uncoupling Agents

2009
Integrating multiple aspects of mitochondrial dynamics in neurons: age-related differences and dynamic changes in a chronic rotenone model.
    Neurobiology of disease, 2011, Volume: 41, Issue:1

    Topics: Aging; Animals; Cells, Cultured; Chronic Disease; Mitochondria; Mitochondrial Diseases; Models, Biological; Neurons; Parkinson Disease; Rats; Rotenone; Substantia Nigra; Uncoupling Agents

2011
Nitrosative stress mediated misfolded protein aggregation mitigated by Na-D-β-hydroxybutyrate intervention.
    Biochemical and biophysical research communications, 2012, Sep-28, Volume: 426, Issue:3

    Topics: 3-Hydroxybutyric Acid; Apoptosis; Carrier Proteins; Caspases; Cell Line, Tumor; Dopaminergic Neurons; Green Fluorescent Proteins; Humans; Mitochondrial Diseases; Necrosis; Nerve Tissue Proteins; Neuroprotective Agents; Nitrates; Nitrosation; Oxidative Stress; Parkinson Disease; Protein Folding; Rotenone

2012
Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders.
    Journal of molecular and cellular cardiology, 2005, Volume: 39, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Mitochondrial Diseases; Myocytes, Cardiac; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Rats; Rotenone; Uncoupling Agents; Vitamin K 3

2005
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:10

    Topics: Cell Line, Tumor; Homeostasis; Humans; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; Rotenone; Superoxide Dismutase; Superoxide Dismutase-1

2006
Mitochondrial and cytosolic thiol redox state are not detectably altered in isolated human NADH:ubiquinone oxidoreductase deficiency.
    Biochimica et biophysica acta, 2007, Volume: 1772, Issue:9

    Topics: Adult; Case-Control Studies; Cells, Cultured; Child, Preschool; Cytosol; Electron Transport Complex I; Fibroblasts; Glutathione; Humans; Infant; Infant, Newborn; Lipid Peroxidation; Mitochondria; Mitochondrial Diseases; Oxidation-Reduction; Rotenone; Sulfhydryl Compounds; Uncoupling Agents

2007
Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, May-07, Volume: 28, Issue:19

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Axons; Cells, Cultured; Down-Regulation; Ganglia, Spinal; Gene Transfer Techniques; Isoenzymes; Mitochondrial Diseases; Nerve Degeneration; Neurons; Nicotinamide-Nucleotide Adenylyltransferase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rotenone; Stress, Physiological; Vincristine

2008
Mouse model of optic neuropathy caused by mitochondrial complex I dysfunction.
    Neuroscience letters, 2002, Jun-28, Volume: 326, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Male; Mice; Mice, Inbred CBA; Mitochondria; Mitochondrial Diseases; Optic Nerve Diseases; Pharmaceutical Vehicles; Quinone Reductases; Retinal Ganglion Cells; Rotenone; Time Factors; Uncoupling Agents

2002