Page last updated: 2024-08-17

rotenone and Disease Models, Animal

rotenone has been researched along with Disease Models, Animal in 364 studies

Research

Studies (364)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.27)	18.7374
1990's	3 (0.82)	18.2507
2000's	60 (16.48)	29.6817
2010's	185 (50.82)	24.3611
2020's	115 (31.59)	2.80

Authors

Authors	Studies
Cheng, R; Hart, AC; Stockwell, BR; Varma, H; Voisine, C	1
Belofsky, G; Brown, M; Cardenas-Garcia, B; Chen, X; Deardorff, K; Dondji, B; Ferreira, D; Fulkerson, S; Gény, C; Jones, K; McCornack, J; McNutt, S; Ray, W; Winterstein, E	1
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ	1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV	1
Balmus, IM; Ciobica, A; Dobrin, R; Doroftei, B; Ilie, OD; Jijie, R; Nicoara, M; Nita, IB; Paduraru, E; Robea, MA	1
Afzal, A; Ahmad, S; Batool, Z; Haider, S; Liaquat, L; Madiha, S; Naqvi, F; Nawaz, A; Sadir, S; Sajid, I; Saleem, S; Shahzad, S; Tabassum, S; Yousuf, S	1
Kaur, J; Khairnar, A; Khunt, D; Rakshe, S; Sharma, M; Sharma, N	1
Chen, CN; Chen, SM; Fang, CH; Lin, YW; Soung, HS; Tseng, HC; Wang, MH	1
Chen, Z; Li, H; Li, Z; Shen, L; Sun, B; Yang, J; Zhang, J; Zhang, N	1
Bowie, AG; Carty, M; Chadderton, N; Farrar, GJ; Finnegan, LK; Kenna, PF; Millington-Ward, S; Palfi, A	1
Castorina, A; Thomas Broome, S	1
Akindahunsi, AA; Akinmoladun, AC; Famusiwa, CD; Josiah, SS; Lawal, AO; Olaleye, MT	1
Brotchie, JM; Chiu, WH; Decher, N; Dolga, AM; Geibl, FF; Griesbach, M; Henrich, MT; Kiper, AK; Komadowski, MA; Koprich, JB; Lee, B; Matschke, LA; Oertel, WH; Rinné, S; Stöhr, A	1
Chen, Z; Gu, H; Hu, Y; Huang, Y; Li, H; Shen, L; Shen, Y; Sun, B; Xu, X; Yang, J; Zhang, J	1
Hou, L; Huang, R; Ruan, Z; Sun, W; Wang, Q; Zhang, D; Zhao, J	1
Sakamula, R; Thong-Asa, W; Yata, T	1
Adebayo, OG; Adebayo, OR; Aduema, W; Ajayi, AM; Akpakpan, E; Ben-Azu, B; Emmanuel, MU; Onuoha, OG; Orji, BO	1
Adebayo, OG; Aduema, W; Akpotu, AE; Asiwe, JN; Ben-Azu, B; Brown, PI; Buduburisi, BR; Igbokwe, V; Kolawole, TA; Onwuka, FC; Onyeleonu, I; Umoren, EB; Wopara, I	1
Choi, HJ; Huh, YE; Kwon, Y; Moon, SH	1
Jakubowski, H; Jodynis-Liebert, J; Kujawska, M; Kurpik, M; Szulc, M; Witucki, Ł; Łukasz Mikołajczak, P	1
Adeyemi, OO; Awogbindin, IO; Ishola, IO; Olubodun-Obadun, TG; Oluwafemi, OA; Onuelu, JE	1
Chiou, A; Dermon, CR; Fanarioti, E; Karathanos, VT; Karvelas, M; Tsarouchi, M; Vasilakopoulou, PB	1
Goel, RK; Ivanov, S; Kumar, S; Lagunin, A	1
Biswas, P; Hasan, W; Jain, J; Jat, D; Yadav, RS	1
Adachi, K; Katagiri, A; Kato, T; Nozaki, K; Sato, H; Satoh, K; Toyoda, H; Yin, DX	1
da Silva, RS; de Melo, MG; de Paiva, IHR; do Nascimento, MIX; Duarte-Silva, EP; Mendonça, IP; Peixoto, CA	1
Bakhtiari, N; Farbood, Y; Ghafouri, S; Hajipour, S; Khoshnam, SE; Mansouri, E; Sarkaki, A; Vastegani, SM	1
Barbiero, JK; Bassani, T; Boschen, S; Da Cunha, C; Ramos, DC; Vital, MABF	1
Hettiarachchi, P; Jarosova, R; Johnson, MA; Niyangoda, SS	1
Gurke, R; Manderscheid, C; Niederberger, E; Schreiber, Y; Tegeder, I; Wilken-Schmitz, A	1
Dolrahman, N; Mukkhaphrom, W; Sutirek, J; Thong-Asa, W	1
Al-Abbasi, FA; Albaqami, FF; Alharthy, KM; Altharawi, A; Althurwi, HN; Alzarea, SI; Kazmi, I; Nadeem, MS	1
Adeyeye, TA; Babatunde, BR; Johnson, VF; Shallie, PD	1
Jiang, Z; Li, H; Li, Y; Ma, J; Qian, Z; Zhou, S; Zhou, X	1
Munissi, JJE; Nyandoro, SS; Shadrack, DM; Stephano, F; Tibashailwa, N	1
Certik, M; Gajdos, P; Hajduchova, D; Halasova, E; Holic, R; Pecova, R; Pokusa, M	1
Atta, R; El-Baz, AA; Imbaby, S; Khalil, S; Mahmoud, OM; Mohammad, HMF	1
Boldt, ABW; Dos Santos, PI; Kretzschmar, GC; Lima, MMS; Macedo, DA; Ribeiro Pinto, LF; Rodrigues, LS; Soares-Lima, SC; Targa, ADS	1
Alturfan, AA; Beler, M; Cansız, D; Emekli-Alturfan, E; Güzel, E; Sezer, Z; Sürmen, MG; Sürmen, S; Ünal, İ; Üstündağ, ÜV	1
Khairnar, A; Sharma, M; Sharma, N	1
Ibarra-Gutiérrez, MT; Orozco-Ibarra, M; Serrano-García, N	1
Dermon, CR; Fanarioti, E; Karathanos, VT; Tsarouchi, M	1
Bavarsad, K; Farbood, Y; Mard, SA; Sarkaki, A; Sheikhpour, E	1
Allodi, S; Correa, CL; de Andrade Gomes, CAB; de Barros, CM; Medeiros, TB; Mello, AA; Nogueira, NDS	1
Atarod, D; Ghasemi, A; Gholami, M; Goliaei, B; Habibi-Kelishomi, Z; Mamashli, F; Meratan, AA; Mohammad-Zaheri, M; Moosavi-Movahedi, F; Obeidi, N; Pirhaghi, M; Saboury, AA; Salmani, B; Shahsavani, MB	1
Catalkaya, E; Colcimen, N; Goceroglu, R; Ozdemir, HS; Sagmanligil, V; Yasar, S; Yunusoglu, O	1
Guo, J; Li, M; Li, W; Ling, L; Liu, Z; Pan, X; Wang, H; Zhang, K; Zhang, M	1
Chaves, NSG; Dahleh, MMM; de Almeida, FP; de Carvalho, AS; Fernandes, EJ; Gonçalves, OH; Guerra, GP; Janner, DE; Leimann, FV; Musachio, EAS; Poetini, MR; Prigol, M; Ramborger, BP; Reginaldo, JC; Roehrs, R	1
Adeyemi, OO; Awogbindin, IO; Ishola, IO; Olajiga, AE; Olubodun-Obadun, TG	1
Azevedo, EM; Chuproski, AP; Ilkiw, J; Lima, MMS; Miloch, J	1
Chen, RS; Chen, YC; Cheng, YC; Chiu, CC; Chiu, TJ; Hsu, CC; Hwang, TL; Liu, HF; Liu, YC; Lu, JC; Wang, HL; Wang, YT; Wei, KC; Weng, YH; Yeh, TH	1
Chang, MY; Cheng, SH; Lee, YZ; Lin, YF; Tsai, YC; Wu, CC	1
Hou, L; Li, S; Liu, J; Wang, Q; Wang, R; Wu, M; Zhang, Y; Zhao, J	1
Ahmed, S; El-Sayed, MM; Kandeil, MA; Khalaf, MM	1
Bakhtiari, N; Farbood, Y; Ghafouri, S; Khoshnam, SE; Mansouri, E; Moradi Vastegani, S; Sarkaki, A	1
Khatri, DK; Khot, M; Pinjala, P; Singh, SB; Sood, A; Srivastava, S; Tryphena, KP	1
Abdelrazik, E; Abdulhai, EA; Elnagdy, MH; Ezz Elregal, FM; Hamza, E; Hassan, HM	1
El-Khatib, AS; F Mohamed, A; Khattab, MM; Mansour, HM	1
Bilal, B; Erbas, O; Erdogan, MA; Kirazlar, M; Yigitturk, G	1
Adeyeye, TA; Babatunde, BR; Ehireme, SE; Shallie, PD	1
Akçay, Y; Gözde Aslan, Ç; Kaplan Algin, A; Mehtap Çinar, G; Şaban Akkurt, S; Tomruk, C; Ulukaya, S; Uyanikgil, Y	1
Afzal, A; Ahmad, S; Batool, Z; Haider, S; Liaquat, L; Madiha, S; Mehdi, BJ; Sadir, S; Sajid, I; Shahzad, S; Tabassum, S	1
Chakkittukandiyil, A; Kothandan, R; Rymbai, E; Selvaraj, D; Selvaraj, J; Sugumar, D	1
Aghsami, M; Ashabi, G; Fartoosi, A; Kheradmand, A; Montazeri, H; Salari, Z; Shariatpanahi, M	1
Bakhtiari, N; Farbood, Y; Ghafouri, S; Khoshnam, SE; Moradi Vastegani, S; Sarkaki, A	1
Abd El Fattah, MA; Ahmed, LA; El-Sayeh, BM; Kandil, EA; Sayed, RH	1
Chen, C; Hu, AL; Li, H; Liu, J; Zhang, BB; Zhang, F	1
Hu, WT; Ji, YF; Liu, X; Lu, H; Sun, GF; Tian, T; Wang, JP; Wang, MH; Yang, HC; Zhang, LM	1
Altinoz, MA; Alturfan, AA; Ateş, PS; Çalışkan-Ak, E; Elmaci, I; Emekli-Alturfan, E; Ünal, İ; Üstündağ, ÜV	1
Chang, KC; Fang, CH; Li, KY; Lin, YW; Soung, HS; Tsai, CC; Tseng, HC; Wang, MH; Yang, CC	1
Hassanzadeh, K; Peluso, I; Rahimmi, A; Rajabi, A	1
Ahmed, YR; Ali, SA; Hamed, MA; Khalil, WKB; Motawi, TK; Sadik, NAH	1
Mahdi, AA; Pandey, S; Rumman, M; Singh, B	1
Chang, HF; Chiu, TL; Huang, HY; Wang, MJ; Wu, HR	1
Hanpude, P; Jangir, D; Kumar, R; Kumar, S; Kumari, R; Maiti, TK; Singh, AK	1
Fu, F; Han, B; He, J; Li, C; Meng, X; Wang, T; Wang, Z; Zhang, L	1
El-Esawy, RO; El-Sakaa, MH; Ibrahim, RR	1
Chen, AD; Jing, YH; Wang, DX; Wang, QJ; Xin, YY; Yin, J	1
Abdel-Moneim, AM; Abdou, HM; Alfwuaires, M; Essawy, AE; Mohammed, NA; Tass, MA	1
Al-Emam, A; Al-Shraim, M; Kranner, B; Moldzio, R; Radad, K; Rausch, WD; Wang, F	1
Asanuma, M; Furukawa, C; Imafuku, F; Isooka, N; Kikuoka, R; Miyazaki, I; Sun, J	1
Jauhari, A; Mishra, S; Shankar, J; Singh, T; Yadav, S	1
Dai, Y; Hou, S; Jiang, N; Lin, Q; Lin, Y	1
Geng, Y; Liu, Y; Xu, W; Zhang, L; Zhang, N	1
Avci, B; Bilge, SS; Bozkurt, A; Günaydin, C; Önger, ME	1
Brunetti, G; Calabrese, EJ; Calabrese, V; Crea, R; Di Rosa, G; Saul, N; Schmitz-Linneweber, C; Scuto, M; Trovato Salinaro, A	1
Batool, Z; Haider, S; Madiha, S	1
Imai, Y	1
Abdel-Hafez, SMN; Abdelwahab, S; Elsebay, SAG; Fouli Gaber, M	1
Awasthi, A; Corrie, L; Kapoor, B; Kaur, J; Khurana, N; Khurana, S; Khursheed, R; Kumar, R; Sharma, N; Singh, SK; Verma, S; Vyas, M	1
Birla, H; Dilnashin, H; Keswani, C; Rai, SN; Rathore, AS; Singh, R; Singh, RK; Singh, SP; Singh, SS; Zahra, W	1
Freeman, JL; Wasel, O	1
Chamorro, B; Chioua, M; Diez-Iriepa, D; Fernández, I; García-Vieira, D; Gonzàlez-Nieto, D; Hadjipavlou-Litina, D; Iriepa, I; López-Muñoz, F; Marco-Contelles, J; Martínez-Murillo, R; Merás-Sáiz, B; Oset-Gasque, MJ	1
Jia, G; Liu, Y; Sun, C; Wang, X; Wang, Y	1
Munissi, JJE; Nyandoro, SS; Siima, AA; Stephano, F	1
Archana, R; Pazhanivel, N; Senthilkumar, S; Shakila, R; Subhashini, S; Thanalakshmi, J	1
Berezhnoy, DS; Fedorova, TN; Nalobin, DS; Troshev, DV	1
Abdel Hafez, SMN; Abdelwahab, SA; Elsebay, SAG; Ibrahim, MFG	1
Imaishi, H; Imaoka, S; Ishida, A; Ishihara, Y; Oguro, A; Siswanto, FM; Yamazaki, T	1
Agostini, JF; Calisto, JFF; de Sá Fonseca, V; de Veras, BO; Magro, JD; Mocelin, R; Rico, E; Santo, GD; Vieira, LD; Wanderley, AG	1
Eroğlu, HA; Makav, M	1
Bhattarai, Y; Farrugia, G; Grover, M; Kandimalla, KK; Kashyap, PC; Margolis, KG; McLean, PJ; Moor, W; Pu, M; Ross, OA; Si, J; Till, L	1
Adolfs, Y; Buijsman, RC; de Man, J; de Wit, J; Gerard Sterrenburg, J; Grobben, Y; Hartog, M; Kraneveld, AD; Muller, M; Pasterkamp, RJ; Perez-Pardo, P; Tutone, M; Uitdehaag, JCM; van Cauter, F; van Doornmalen, AM; Vu-Pham, D; Willemsen-Seegers, N; Zaman, GJR	1
Kumar, P; Kumar, S	1
Cielecka-Piontek, J; Ewertowska, M; Ignatowicz, E; Jodynis-Liebert, J; Kujawska, M; Kurpik, M; Zalewski, P	1
Berger, JP; Constable, R; Di Natale, M; Diwakarla, S; Finkelstein, DI; Furness, JB; Kauhausen, J; Lee, S; McQuade, RM; Parish, CL; Ringuet, MT; Singleton, LM; Wu, H	1
Abaimov, D; Berezhnoy, D; Fedorova, T; Kulikova, O; Muzychuk, O; Nalobin, D; Stvolinsky, S; Troshev, D	1
Khurana, N; Muthuraman, A; Sharma, N; Utreja, P	1
Hickey, MA; Innos, J	1
Date, AA; Kalaria, D; Kalia, Y; Patel, P; Patravale, V; Pol, A	1
Ahmed, YR; Aziz, WM; Hamed, MAA; Khalil, WKB; Naser, AFA	1
Maegawa, H; Niwa, H	1
Corbo, M; Feligioni, M; Hassanzadeh, K; Izadpanah, E; Maccarone, R; Moloudi, MR; Rahimmi, A	1
Du, G; Kong, D; Liang, Y; Song, J; Wei, G; Zhao, X; Zhou, Q	1
da Silva, RCB; de Toledo Simões, JG; Dos Santos Bioni, V; Henrique, E; Ramos, AC; Rosenstock, TR; Siena, A; Varga, TG	1
Chen, S; Gao, Y; Liu, Y; Tan, J; Wang, Y; Wu, H; Xiao, Z; Yan, H; Yi, S	1
Altinoz, MA; Alturfan, AA; Cansız, D; Elmacı, İ; Emekli-Alturfan, E; Ünal, İ; Üstündağ, ÜV	1
Chen, C; Liang, Y; Lu, Y; Tang, L; Wang, W; Zhang, Z; Zhao, Y; Zhu, G	1
Aoshima, K; Aoyama, Y; Hara, H; Inagaki, S; Iwata, Y; Nakamura, S; Shimazawa, M	1
Fu, L; Han, B; Han, Y; He, J; Li, C; Wang, T; Wang, Z; Zhao, Y	1
Jedsadavitayakol, S; Jutarattananon, S; Thong-Asa, W	1
Guo, Q; Liu, Z; Smith, WW; Wang, B; Wang, X; Zhu, Y	1
Cole, NJ; Hesselson, D; Nguyen, DT; Olzomer, EM; Phillips, BR; Poon, GP; Puvanendran, A; Zhang, Y	1
Anusha, C; Joseph, LD; Sumathi, T	1
Hu, S; Mao, Y; Wang, J; Wang, R; Xie, J; Zhao, X	1
Cai, K; Li, W; Scotti, AM; Tain, RW; Zhou, XJ	1
Ebrahimi, SS; Hassanzadeh, K; Izadpanah, E; Oryan, S	1
Jagota, A; Mattam, U	2
Du, G; Du, L; Yang, Y; Zhang, W; Zhang, X	1
Batool, Z; Haider, S; Liaquat, L; Madiha, S; Perveen, T; Sadir, S; Shahzad, S; Tabassum, S	1
Cao, X; Kuang, L; Lu, Z	1
Concannon, RM; Dowd, E; McCabe, K; McKernan, DP	1
Du, G; Du, L; Yang, Y; Zhang, W; Zhang, X; Zhou, Q	1
Almeida, MF; Almeida, RS; Cardoso, SM; Chaves, RS; Demasi, M; Fernandes, T; Ferrari, MFR; Lima, NCR; Melo, KP; Netto, LES; Oliveira, EM; Silva, CM	1
Chen, WJ; Du, JK; Hu, X; Li, DX; Liu, YJ; Wang, CN; Yu, Q; Zhu, XY	1
Charkhat Gorgich, EA; Khajavi, O; Komeili, G; Salimi, S; Sarbishegi, M	1
Bao, Z; Chao, H; Fu, X; Ji, J; Li, Z; Lin, C; Liu, N; Liu, Y; Wang, X; Xu, X; You, Y	1
Babu, B; Hammock, BD; Hwang, SH; Krishnamurthy, PT; Lakkappa, N; Yamjala, K	1
Andrade, RJ; Anguita, J; Azkargorta, M; Barbier-Torres, L; Crespo, J; Delgado, TC; Elortza, F; Fernández-Ramos, D; Fernández-Tussy, P; Guitiérrez-de-Juan, V; Hernández-Alvarez, MI; Iruzubieta, P; Lachiondo-Ortega, S; Lopitz-Otsoa, F; Lu, SC; Lucena, MI; Martínez-Chantar, ML; Masson, S; Mato, JM; McCain, MV; Navasa, N; Reeves, H; Rincón, M; Simon, J; Taibo, D; Varela-Rey, M; Villa, E; Zorzano, A; Zubiete-Franco, I	1
Abdel-Tawab, AM; Bahaa, N; Khalifa, AE; Salama, RM; Schaalan, MF; Tadros, MG	1
Bruchhaus, I; El-Kholy, S; Fink, C; Hoffmann, J; Nolte, S; Roeder, T; Stephano, F; von Frieling, J	1
Neerati, P; Palle, S	1
Bahgat, AK; Hedya, SA; Safar, MM	2
Huang, X; Tian, H; Yang, J	1
Bobrovskaya, L; Johnson, ME; Stringer, A	1
Andrade-da-Costa, BLDS; Augusto, RL; Braz, GRF; de Souza, FTC; de Souza, IA; Lafayette, SSL; Lagranha, CJ; Medeiros-Linard, CFB; Perreira, RCR; Sereniki, A; Smailli, SS; Trevisan, MTS; Wanderley, AG	1
Bicca, MA; Hara, DB; Morais, LH; Poli, A; Takahashi, RN	1
Mbiydzenyuy, NE; Ninsiima, HI; Pieme, CA; Valladares, MB	1
Bao, XX; Ding, H; Li, WW; Ma, HH; Zhu, M	1
Ahmed, A; El-Sayed, EK; Morsy, EE; Nofal, S	1
Abin-Carriquiry, JA; Costa, G; Dajas, F; Ferreira, M; Mouhape, C; Prunell, G	1
Andrabi, SS; Parveen, S; Parvez, S; Rasheed, MZ; Salman, M; Shaquiquzzaman, M; Tabassum, H	1
He, D; Lei, L; Liu, M; Lou, D; Lu, S; Shi, Y; Song, Y; Wang, Z; Wu, S	1
Aurich, MF; Lima, MMS; Noseda, ACD; Rodrigues, LS; Targa, ADS	1
da Silva Ribeiro, CY; de Aguiar Montenegro, N; de Andrade, RR; Del Bel Guimarães, E; Domingues, ACM; Ferreira, GG; Horst, CH; Schlemmer, F; Titze-de-Almeida, R; Titze-de-Almeida, SS	1
Ahmed, E; Alshareef, DM; El-Kherbetawy, MK; ElSayed, MH; Elsherbiny, NM; Mehanna, ET; Moustafa, YM; Zaitone, SA	1
Fang, Q; Homberg, JR; Li, W; Liao, P; Liu, C; Luan, Y; Meng, X; Shan, L; Shen, J; Swaab, DF; Wang, J; Zhou, P	1
Prabu, K; Rajasankar, S; Ramkumar, M; Swaminathan Johnson, WM; Venkatesh Gobi, V	2
Haider, S; Madiha, S	1
Dodiya, HB; Engen, PA; Forsyth, CB; Green, SJ; Keshavarzian, A; Kordower, JH; Naqib, A; Pahan, K; Patel, J; Roy, A; Shaikh, M; Shannon, KM; Voigt, RM	1
Amoroso, S; Bastioli, G; Calabresi, P; Castaldo, P; Magi, S; Piccirillo, S; Tozzi, A	1
Chowdhury, NR; Dorieux, FWC; Fagotti, J; Ilkiw, JL; Lima, MMS; Louzada, FM; Middleton, B; Noseda, ACD; Pennings, JLA; Rodrigues, LS; Scarante, FF; Skene, DJ; Swann, JR; Targa, ADS; van der Veen, DR	1
Feng, B; Mu, J; Qi, W; Tang, JY; Wei, Y; Wu, Q; Yang, LL; Zeng, W; Zhang, Q	1
Bandez, MJ; Boveris, A; López-Cepero, JM; Navarro, A; Valdez, LB; Zaobornyj, T	1
Abd El-Lateef, AS; Alzahrani, S; Elkazaz, AY; Elshaer, RE; Ezzat, W; Mohammad, HMF; Toraih, E; Zaitone, SA	1
Castro, S; De Miranda, BR; Fazzari, M; Greenamyre, JT; Rocha, EM	1
Abah, VO; Adebambo, OI; Aladelokun, OB; Awogbindin, IO; Ezekiel, IO; Farombi, EO; Farombi, TH; Izomoh, ER; Oladele, JO	1
Ansari, SA; Azimullah, S; Javed, H; Meeran, MFN; Ojha, S	1
Bhurtel, S; Choi, DY; Choi, H; Hong, JT; Katila, N; Maharjan, S; Neupane, S; Srivastav, S	1
Gorev, NP; Ionov, ID; Pushinskaya, II; Shpilevaya, LA	1
Ding, G; Ge, W; Hua, H; Huang, S; Jia, Z; Qian, Y; Yuan, H; Zhang, A; Zhang, Y; Zhang, Z	1
Adem, A; Azimullah, S; Beiram, R; Jalal, FY; Jayaraj, RL; Meeran, MFN; Ojha, SK	1
Chen, J; Hu, H; Li, LX; Liu, CF; Lv, DJ; Wang, F; Wei, SZ; Xie, AM	1
Bu, J; He, Y; Liu, J; Qiao, X	1
Benedí, J; Delgado, M; Fernández-Ruiz, J; García-Arencibia, M; García-García, L; Gómez del Rio, MA; Iglesias, I; Pozo, MA; Sánchez-Reus, MI	1
Ali, SF; Beaudoin, MA; Binienda, ZK; Gough, B; Imam, SZ; Mohammed-Saeed, L; Paule, MG; Sarkar, S	1
Gai, WP; Meedeniya, A; Pountney, DL; Rcom-H'cheo-Gauthier, A; Sharry, S; Weetman, J; Wong, MB	1
Bähr, M; Bertsch, U; Bötzel, K; Deeg, AA; Eiden, M; Frank, T; Geissen, M; Giese, A; Griesinger, C; Groschup, M; Hirschberger, T; Krauth, JJ; Kretzschmar, H; Leidel, F; Leonov, A; Levin, J; Mitteregger-Kretzschmar, G; Pan-Montojo, F; Pilger, J; Prix, C; Ryazanov, S; Samwer, M; Schmidt, F; Shi, S; Tavan, P; Teichmann, U; Uhr, M; Urlaub, H; Wagner, J; Weishaupt, JH; Zinth, W; Zweckstetter, M	1
Ahmad, ST; O'Brien, LM; St Laurent, R	1
Ge, JB; Gu, JH; Liang, ZQ; Qin, ZH; Wang, Z; Wu, F	1
de los Ríos, C; Estrada, M; González-Lafuente, L; Lajarín-Cuesta, R; López, MG; Lorrio, S; Marco-Contelles, J; Martínez-Sanz, FJ; Rodríguez-Franco, MI; Romero, A; Samadi, A; Villarroya, M	1
Huang, J; Jia, M; Lin, Z; Liu, L; Mohamed, AA; Wang, T; Xiong, J; Xiong, N; Yang, H; Zhang, X; Zhang, Z	1
Lu, J; Shi, JP; Shi, JQ; Tian, YY; Wu, L; Xie, W; Zhang, YD	1
Fu, Q; Liu, X; Wang, Y; Wu, Z	1
Chen, CL; Chen, YR; Chilian, WM; Dyck, JR; Enrick, M; Hardwick, JP; Kolz, C; Pung, YF; Sam, WJ; Stevanov, K; Thakker, P; Yin, L	1
Alvarez-Fischer, D; Fuchs, J; Grünewald, A; Guerreiro, S; Hartmann, A; Hirsch, EC; Lombès, A; Lu, L; Michel, PP; Noelker, C; Oertel, WH; Vulinović, F	1
Marella, M; Matsuno-Yagi, A; Patki, G; Yagi, T	1
Castro, MA; Da Cunha, C; Delattre, AM; Dombrowski, PA; Dos Santos, AC; Ferraz, AC; Jose, EA; Lima, MM	1
Berndt, N; Bulik, S; Holzhütter, HG	1
Gajbhiye, A; Khurana, N	1
Ambasta, RK; Anand, K; Kumar, P; Sarkar, A; Sonia Angeline, M	1
Ding, QF; Liu, CB; Lu, FB; Pan, HB; Wang, R	1
Cannon, JR; Greenamyre, JT; Tapias, V	2
Armstrong, SM; Moore, C; Willis, GL	1
Aglan, H; Ahmed, H; Atta, H; Ghazy, M; Salem, A	1
Chadderton, N; Farrar, GJ; Gobbo, OL; Kenna, PF; Mansergh, FC	1
Carriere, CH; Kang, NH; Niles, LP	3
Nehru, B; Thakur, P	1
Chen, K; Chen, L; Li, S; Li, Y; Liu, Z; Long, C; Peng, A; Tang, H; Tang, M; Wu, W; Xiang, M; Xie, C; Yang, J; Ye, H	1
Casson, RJ; Chidlow, G; Han, G; Wood, JP	1
Lee, D; Podolsky, E; Qi, C; Varga, SJ	1
Abd El-Rehim, HA; El-Ghazaly, MA; Rashed, ER	1
Ahmad, ST; Liao, J; Morin, LW	1
Aurich, MF; Da Cunha, C; Lima, MM; Noseda, AC; Rodrigues, LS; Targa, AD; Vital, MA	1
Chang, YM; Chen, CH; Chen, CL; Chen, YJ; Chiu, CC; Huang, YC; Lai, SC; Lu, CS; Mochly-Rosen, D; Wang, HL; Wu-Chou, YH; Yeh, TH	1
Bétourné, A; Ferré, CA; Foret, C; Gonzalez-Dunia, D; Hunot, S; Monnet, Y; Peyrin, JM; Szelechowski, M; Thouard, A	1
Abdallah, DM; Al-Shorbagy, MY; Arab, HH; Nassar, NN	1
Alam, M; John, N; Krauss, JK; Schwabe, K; von Wrangel, C	1
Guttierez, JC; Liu, L; Marella, M; Martinez, JC; Matsuno-Yagi, A; Patki, G; Philip, AL; Thomas, BB; Yagi, T; Zhang, L	1
Abdelkader, NF; Safar, MM; Salem, HA	1
Bobrovskaya, L; Johnson, ME	1
Biener-Ramanujan, E; Ramanujan, VK; Xu, Q; Yang, W	1
Denny Joseph, KM	1
Hassanzadeh, K; Izadpanah, E; Khosrobakhsh, F; Moloudi, MR; Rahimmi, A	1
Bayır, H; Domingues, MR; Greenamyre, JT; Kagan, VE; Kapralova, VI; Maciel, E; McCoy, J; Polimova, AM; Sanders, LH; Tyurin, VA; Tyurina, YY; Vikulina, AS; Winnica, DE	1
Calogero, A; Cappelletti, G; Cartelli, D; Casagrande, F; De Gregorio, C; Pezzoli, G	1
Nikonenko, AG; Voitenko, LP	1
Bai, Q; Burton, EA; Cannon, JR; El Ayadi, A; Greenamyre, JT; Hastings, TG; Horowitz, MP; Shah, V; Tapias, V; Zharikov, AD	1
Bai, J; Guan, Q; Liu, Z; Wang, M; Wang, X; Yan, Z; Yang, L; Zhang, Y	1
Flatters, SJ; Griffiths, LA	1
Gao, Q; Ou, Z; Tong, Q; Wu, L; Zhang, Y; Zhu, D	1
Cheng, X; Li, S; Liu, B; Lv, C; Ma, Y; Mao, W; Sun, J; Zhang, J	1
Dowd, E; Feehan, J; Moriarty, N; Naughton, C; O'Toole, D	1
Bakshi, R; Gu, L; Liu, L; Wang, ST; Xia, N; Yang, H; Yang, HM; Zhang, H; Zhang, Q	1
Abul Khair, SB; Azimullah, S; Haque, ME; Javed, H; Ojha, S	1
Chen, LL; Durairajan, SS; Han, QB; Huang, YY; Li, M; Liu, LF; Lu, JH; Song, JX; Zeng, Y	1
Chakrapani, LN; Kaliappan, K; Krishnan, TR; Narasimhan, KK; Paul, L; Periandavan, K; Radhakrishnan, R; Ravi, DB; Sathyamoorthy, YK; Singh, A; Srinivasan, A; Velusamy, P	1
Rajini, PS; Rao, SV; Yenisetti, SC	1
Jiang, T; Ou, Z; Tong, Q; Wu, L; Zhang, Y; Zhu, D	1
Elbatsh, MM; Gaballah, HH; Tahoon, NM; Zakaria, SS	1
Concannon, RM; Dowd, E; Finn, DP; Okine, BN	1
Vargas Núñez, JA	1
Cannon, J; Wise, JP	1
Abdel-Tawab, AM; Esmat, A; Khalifa, AE; Michel, HE; Tadros, MG	1
Misra, K; Naveen Kumar, HN; Pandareesh, MD; Shrivash, MK; Srinivas Bharath, MM	1
Cai, X; Cao, P; Chen, B; Chen, J; Cheng, X; Hu, Z; Lu, W; Shen, J; Sun, X; Wang, X; Wu, L; Yan, H; Yang, J; Yang, Y; Ye, J; Zhou, Q	1
Dowd, E; Kirik, D; Naughton, C; O'Toole, D	1
He, X; Ren, J; Wang, Y; Yuan, J; Zhao, Y	1
Almeida, MF; D'Unhao, AM; Ferrari, MF; Silva, CM	1
Feng, D; Gong, J; He, X; Ji, J; Jin, T; Li, L; Liu, C; Sun, H; Sun, J; Xiang, L; Yue, S; Zhou, R	1
Boyd, J; Han, A	1
Hu, LF; Liu, CF; Liu, W; Sima, Y; Wang, F; Wang, H; Wang, Y; Yang, J; Zhong, ZM	1
Deepthy, J; Ezhil, P; Kalaiselvi, P; Kishore Kumar, SN; Saraswathi, U; Thangarajeswari, M; Yogesh Kanna, S	1
Yang, Q; Ye, Y; Zhao, C; Zhao, J	1
Jungling, A; Kiss, T; Maasz, G; Petrovics, D; Pirger, Z; Reglodi, D; Rivnyak, A; Tamas, A; Zrinyi, Z	1
Ho, PW; Ho, SL; Kung, MH; Lam, CS; Leung, GC; Li, L; Liu, HF; Pang, SY; Ramsden, DB	1
Arambakkam Janardhanam, V; Gopi, M	1
Abd El Fattah, MA; Badawi, GA; El Sayed, MI; Zaki, HF	1
Abdin, AA; Hamouda, HE	1
Hayashi, T; Kawasaki, A; Kotake, Y; Nakachi, K; Ohta, S; Sugihara, K; Trosko, JE	1
Allen, AL; Luo, C; Montgomery, DL; Rajput, A; Rajput, AH; Robinson, CA	1
Nehru, B; Verma, R	1
Gonzalez-Lima, F; John, JM; Lee, J; Rojas, JC	1
Cannon, JR; Drolet, RE; Greenamyre, JT; Honick, AS; Na, HM; Tapias, V	1
Greene, JG; Noorian, AR; Srinivasan, S	1
Falk, T; Sherman, SJ; Zhang, S	1
Collado, C; Diaz-Ruiz, A; Guizar-Sahagún, G; Orozco-Suarez, S; Ríos, C; Salgado-Ceballos, H; Torres, JL; Torres, S; Vázquez, ME	1
Daniels, WM; Hattingh, S; Pienaar, IS; Schallert, T	1
Cannon, JR; Drolet, RE; Greenamyre, JT; Montero, L	1
Alam, M; Danysz, W; Dekundy, A; Schmidt, WJ	1
Contestabile, A; Gatta, V; Monti, B; Piretti, F; Raffaelli, SS; Virgili, M	1
Cicchetti, F; Drouin-Ouellet, J; Gross, RE	1
Hosamani, R	1
Hillard, CJ; Kalivendi, SV; Kalyanaraman, B; Yedlapudi, D	1
Feng, L; Huang, R; Jiang, C; Ke, W; Liu, Y; Pei, Y; Wu, D	1
Cao, X; Chen, C; Huang, J; Jia, M; Liang, Z; Lin, Z; Liu, X; Sun, S; Wang, F; Wang, T; Xiong, J; Xiong, N; Zhang, Z	1
Bian, JS; Dawe, GS; Hu, G; Hu, LF; Lu, M; Tiong, CX	1
Cannon, JR; Drolet, R; Greenamyre, JT; Mastroberardino, PG	1
Anichtchik, O; Dening, Y; Funk, RH; Gille, G; Jackson, S; Jung, R; Knels, L; Pan-Montojo, F; Pursche, S; Reichmann, H; Spillantini, MG	1
Ago, T; Fu, C; Kuroda, J; Li, H; Pain, J; Sadoshima, J	1
Bayersdorfer, F; Botella, JA; Schneuwly, S; Voigt, A	1
Behl, C; Hajieva, P; Kern, A; Mocko, JB; Moosmann, B	1
Duenas, VJ; Garzon-Muvdi, T; Mahajan, R; Quiñones-Hinojosa, A; Shah, A	1
Ayton, S; Culvenor, JG; Finkelstein, DI; George, S; Li, QX; Masters, CL; Mok, SS; Nurjono, M	1
Andreatini, R; Barbieiro, J; Dombrowski, PA; Lima, MM; Santiago, RM; Vital, MA	1
Mackay-Sim, A; Meedeniya, AC; Nguyen, MN; Norazit, A	1
Kuruvilla, KP; Nandhu, MS; Paul, J; Paulose, CS	1
Cannon, JR; Greenamyre, JT	1
Funk, RH; Pan-Montojo, FJ	1
Caldwell, GA; Caldwell, KA; Hamamichi, S; Harrington, AJ; Schieltz, JM; Slone, SR; Standaert, DG; Yacoubian, TA	1
Dowd, E; Mulcahy, P; Paucard, A; Rea, K; Walsh, S	1
Choi, WS; Palmiter, RD; Xia, Z	1
Chauhan, S; Kaur, H; Sandhir, R	1
Cao, X; Chen, C; Hou, L; Huang, J; Jia, M; Liang, Z; Lin, Z; Sun, S; Wang, T; Xiong, N; Yang, H; Zhang, Y; Zhang, Z; Zhao, Y	1
Celik, T; Gürsoy, M; Isik, AT; Kayir, H; Ulusoy, GK; Uzbay, TI	1
Barcia, E; Fernández, M; Fernández-Carballido, A; Negro, S; Slowing, K	1
Abdin, AA; Sarhan, NI	1
Beller, GA; Brennan, KM; Broisat, A; Glover, DK; Goodman, NC; Hanrahan, SM; Janabi, M; Reutter, BW; Ruiz, M; Schaefer, S; VanBrocklin, HF; Watson, DD	1
Ariza, D; Barbiero, JK; Bortolanza, M; Da Cunha, C; Dombrowski, PA; Lima, MM; Moreira, CG; Sabioni, P; Vital, MA	1
Ariga, H; Funayama, R; Honda, T; Inden, M; Ito, N; Kitamura, Y; Nishimura, K; Niwa, R; Taira, T; Takahashi, K; Takata, K; Taniguchi, T	1
Li, YL; Liu, J; Pipinos, II; Tu, H; Zhang, L; Zhu, Z	1
Bové, J; Perier, C	1
Dowd, E; Kirik, D; Mulcahy, P; O'Brien, T; O'Doherty, A; Paucard, A	2
Tieu, K	1
Chesselet, MF; McDowell, K	1
Cuenca, N; Esquiva, G; Esteve-Rudd, J; Lax, P; Madrid, JA; Otalora, BB	1
Argüelles, S; Bández, MJ; Cano, J; de Pablos, RM; Delgado-Cortés, MJ; Espinosa-Oliva, AM; Hernández-Romero, MC; Herrera, AJ; Machado, A; Mauriño, R; Santiago, M; Sarmiento, M; Venero, JL; Villarán, RF	1
Hattori, H; Ikegaya, H; Inden, M; Ishikawa, N; Kitamura, Y; McLean, S; Ueda, S; Yoshimoto, K	1
Chen, C; Ghoorah, D; Huang, J; Jia, M; Kong, X; Lin, Z; Long, X; Wang, T; Xiong, J; Xiong, N	1
ElDakroory, SAE; Elghaffar, HA; ElHak, SG; Elhusseiny, M; ElTantawy, D; Ghanem, AA; Salama, M	1
Chen, YP; Feng, XY; Li, WW; Zhang, QQ; Zhu, M	1
Barcia, E; Fernández, M; Fernández-Carballido, A; Garcia, L; Negro, S; Slowing, K	1
Anklin, C; Erb, M; Gueven, N; Heitz, FD; Pernet, V; Robay, D	1
Goswami, P; Kamat, PK; Nath, C; Patro, IK; Singh, S; Swarnkar, S	1
Cannon, JR; Dail, MK; Geghman, KD; Greenamyre, JT; Li, C; Sew, T; Tapias, V	1
Arias-Carrión, O; El-Gamal, M; Ellaithy, A; Helmy, B; Mohamed, M; Salama, M; Sheashaa, H; Sobh, M; Tantawy, D	1
Sanders, LH; Timothy Greenamyre, J	1
Haobam, R; Karuppagounder, SS; Madathil, SK; Mohanakumar, KP; Pandey, M; Rajamma, U	1
El-Gamal, A; El-Gamal, M; Ellaithy, A; Helmy, B; Mohamed, M; Reda, A; Salama, M; Sheashaa, H; Sobh, M; Tantawy, D	1
Johnson, GC; Shanley, PF	1
Betarbet, R; Greenamyre, JT; Kim, JH; Sherer, TB	2
Trojanowski, JQ	1
Champy, P; Féger, J; Hirsch, EC; Höglinger, GU; Michel, PP; Oertel, WH; Parain, K; Prigent, A; Ruberg, M	1
Orth, M; Tabrizi, SJ	1
Bové, J; Perier, C; Przedborski, S; Vila, M	1
Breidert, T; Cohen-Salmon, C; Feger, J; Hirsch, EC; Höglinger, G; Launay, JM; Parain, K; Prigent, A; Rousselet, E; Ruberg, M	1
Betarbet, R; Greenamyre, JT; Kim, JH; Matsuno-Yagi, A; Miller, GW; Richardson, JR; Seo, BB; Sherer, TB; Testa, CM; Yagi, T	1
Blanchet, J; Cicchetti, F; Gould, P; Lapointe, N; Martinoli, MG; Rouillard, C; St-Hilaire, M	1
Akaike, A; Kanki, R; Kawamata, J; Kihara, T; Nakamizo, T; Sawada, H; Shibasaki, H; Shimohama, S; Uemura, K; Yamashita, H	1
Uversky, VN	1
French, BA; French, SW; Fu, P; Li, J	1
Caboni, P; Casida, JE; Greenamyre, JT; Na, HM; Sherer, TB; Taylor, G; Zhang, N	1
Alam, M; Schmidt, WJ	1
Ding, JH; Hu, G; Liu, SY; Liu, X; Long, Y; Sun, YH; Wang, F; Wang, H; Wu, J; Yang, Y; Yao, HH	2
Brown, R; Cussen, V; García-García, F; Krueger, JM; Ponce, S	1
Pasha, MK; Rajput, AH; Sharma, RK	1
Gu, W; Huang, J; Li, Y; Liu, H; Xu, Z; Yan, Z; Yang, Y; Zhu, X	1
Alfonso, A; Burnam, L; Hoener, M; Liu, L; Perier, C; Przedborski, S; Rodrigues, CM; Saha, S; Sluder, A; Steer, C; Ved, R; Westlund, B; Wolozin, B	1
Dikalov, S; Greenamyre, JT; Panov, A; Shalbuyeva, N; Sherer, T; Taylor, G	1
Lubet, RA; Tan, Q; Wang, Y; Yan, Y; You, M	1
Bence, NF; Betarbet, R; Canet-Aviles, RM; Cookson, MR; Greenamyre, JT; Kim, JH; Klinefelter, G; Kopito, R; Lund, S; Mastroberardino, PG; McLendon, C; Na, HM; Seo, BB; Sherer, TB; Taylor, G; Yagi, A; Yagi, T	1
Gonzalez-Lima, F; Rojas, JC; Zhang, X	1
Joseph, EK; Levine, JD	1
Mohanakumar, KP; Saravanan, KS; Senthilkumar, KS; Sindhu, KM	1
Flotte, TR; Matsuno-Yagi, A; Nakamaru-Ogiso, E; Seo, BB; Yagi, T	1
Casarejos, MJ; García de Yébenes, J; Mena, MA; Menéndez, J; Rodríguez-Navarro, JA; Solano, RM	1
Bernardi, G; Calabresi, P; Costa, C; Martella, G; Mercuri, NB; Pisani, A; Shen, J; Tscherter, A	1
Kordower, JH; O'Malley, J; Soderstrom, K; Steece-Collier, K	1
Hirsch, EC; Höglinger, GU; Oertel, WH	1
Ayala, A; Cano, J; Machado, A; Venero, JL	1
Ding, JH; Hu, G; Sun, XL; Wu, JY; Yao, HH; Zhou, F	1
Elliott, CJ; Hernádi, L; Hiripi, L; Szabó, H; Vehovszky, A	1
Ariga, H; Inden, M; Kaneko, M; Kitamura, Y; Kobayashi, Y; Okuma, Y; Shimohama, S; Taira, T; Takata, K; Takeuchi, H; Taniguchi, T; Yanagida, T; Yoshimoto, K	1
Chan, CS; Guzman, JN; Ilijic, E; Mercer, JN; Meredith, GE; Rick, C; Surmeier, DJ; Tkatch, T	1
Cavada, C; Cuadrado, A; de Sagarra, MR; Rojo, AI	1
Kim, JH; Kim, KW; Lee, HY; Shin, JY; Yu, YS	1
Ching, CH; Chuang, JI; Huang, JY; Lin, CH	1
Khanna, P; Nehru, B; Sharma, SK; Verma, R	1
Kennett, FF; Ruth, RC; Weglicki, WB	1
Bruns, R; Liss, B; Roeper, J	1
Duan, W; Mattson, MP	1
Friedrich, MJ	1
Helmuth, L	1
Heinemann, U; Schuchmann, S	1
Gonzalez-Lima, F; Jones, D; Zhang, X	1

Reviews

24 review(s) available for rotenone and Disease Models, Animal

Article	Year
Rotenone-Induced Model of Parkinson's Disease: Beyond Mitochondrial Complex I Inhibition. Molecular neurobiology, 2023, Volume: 60, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopamine; Electron Transport Complex I; Oxidopamine; Parkinson Disease; Rats; Rotenone	2023
Use of invertebrates to model chemically induced parkinsonism-symptoms. Biochemical Society transactions, 2023, 02-27, Volume: 51, Issue:1 Topics: Animals; Disease Models, Animal; Humans; Invertebrates; Parkinson Disease; Parkinsonian Disorders; Rotenone	2023
Rotenone: from modelling to implication in Parkinson's disease. Folia neuropathologica, 2019, Volume: 57, Issue:4 Topics: Animals; Cell Death; Disease Models, Animal; Humans; Inflammation; Parkinson Disease; Reactive Oxygen Species; Rotenone	2019
Chemical and Genetic Zebrafish Models to Define Mechanisms of and Treatments for Dopaminergic Neurodegeneration. International journal of molecular sciences, 2020, Aug-20, Volume: 21, Issue:17 Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Gene Knockdown Techniques; Neurotoxicity Syndromes; Oxidopamine; Paraquat; Parkinson Disease; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone; Zebrafish; Zebrafish Proteins	2020
Using Rotenone to Model Parkinson's Disease in Mice: A Review of the Role of Pharmacokinetics. Chemical research in toxicology, 2021, 05-17, Volume: 34, Issue:5 Topics: Animals; Disease Models, Animal; Electron Transport Complex I; Mice; Parkinson Disease; Rotenone	2021
Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease. Neurobiology of disease, 2020, Volume: 135 Topics: Animals; Brain; Disease Models, Animal; Gastrointestinal Diseases; Gastrointestinal Microbiome; Humans; Parkinson Disease; Rotenone	2020
An update on the rotenone models of Parkinson's disease: their ability to reproduce the features of clinical disease and model gene-environment interactions. Neurotoxicology, 2015, Volume: 46 Topics: Animals; Disease Models, Animal; Gene-Environment Interaction; Humans; Insecticides; Parkinson Disease; Rotenone	2015
Linking microtubules to Parkinson's disease: the case of parkin. Biochemical Society transactions, 2015, Volume: 43, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Disease Models, Animal; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Microtubules; Mutation; Neurons; Parkinson Disease, Secondary; Protein Serine-Threonine Kinases; Rotenone; Tubulin; Ubiquitin-Protein Ligases	2015
Deguelin and Its Role in Chronic Diseases. Advances in experimental medicine and biology, 2016, Volume: 929 Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Chronic Disease; Disease Models, Animal; Drug Discovery; Electron Transport Complex I; Enzyme Inhibitors; Humans; Molecular Structure; Parkinson Disease, Secondary; Phytotherapy; Plants, Medicinal; Risk Factors; Rotenone; Signal Transduction	2016
Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models? Trends in pharmacological sciences, 2009, Volume: 30, Issue:9 Topics: Animals; Disease Models, Animal; Environmental Exposure; Humans; Maneb; Paraquat; Parkinson Disease, Secondary; Pesticides; Rotenone	2009
Lessons from the rotenone model of Parkinson's disease. Trends in pharmacological sciences, 2010, Volume: 31, Issue:4 Topics: Animals; Disease Models, Animal; Environmental Exposure; Humans; Parkinson Disease; Parkinson Disease, Secondary; Rotenone	2010
Animal models of neurological disease. Advances in experimental medicine and biology, 2010, Volume: 671 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; Amyloid beta-Protein Precursor; Animals; Antipsychotic Agents; Brain Ischemia; Central Nervous System; Central Nervous System Stimulants; Disease Models, Animal; Humans; Methamphetamine; Nervous System Diseases; Neurotoxins; Oxidopamine; Reserpine; Rotenone; Uncoupling Agents	2010
Neurotoxic in vivo models of Parkinson's disease recent advances. Progress in brain research, 2010, Volume: 184 Topics: Animals; Disease Models, Animal; Dopamine; Humans; MPTP Poisoning; Neurotoxicity Syndromes; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Rotenone; Sympatholytics; Uncoupling Agents	2010
Neurotoxin-based models of Parkinson's disease. Neuroscience, 2012, Jun-01, Volume: 211 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Cell Death; Disease Models, Animal; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease, Secondary; Rotenone	2012
A guide to neurotoxic animal models of Parkinson's disease. Cold Spring Harbor perspectives in medicine, 2011, Volume: 1, Issue:1 Topics: Animals; Corpus Striatum; Disease Models, Animal; Haplorhini; Lewy Bodies; Mice; MPTP Poisoning; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rotenone; Substantia Nigra	2011
Animal models of the non-motor features of Parkinson's disease. Neurobiology of disease, 2012, Volume: 46, Issue:3 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Humans; Hydroxydopamines; MPTP Poisoning; Neurotoxins; Parkinson Disease; Parkinson Disease, Secondary; Risk Factors; Rotenone; Uncoupling Agents	2012
Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models. Critical reviews in toxicology, 2012, Volume: 42, Issue:7 Topics: alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Humans; Lewy Bodies; Mitochondria; Oxidative Stress; Parkinson Disease; Proteolysis; Rotenone; Substantia Nigra	2012
Oxidative damage to macromolecules in human Parkinson disease and the rotenone model. Free radical biology & medicine, 2013, Volume: 62 Topics: Animals; Disease Models, Animal; DNA Damage; Dopaminergic Neurons; Humans; Lipid Metabolism; Oxidative Stress; Parkinson Disease; Parkinson Disease, Secondary; Proteins; Rotenone	2013
Models of Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2003, Volume: 18, Issue:7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; DNA Mutational Analysis; Dopamine Agents; Humans; Mice; Mice, Knockout; Mice, Transgenic; Models, Genetic; Nerve Tissue Proteins; Oxidopamine; Parkinsonian Disorders; Risk Factors; Rotenone; Substantia Nigra; Synucleins	2003
Animal models of Parkinson's disease in rodents induced by toxins: an update. Journal of neural transmission. Supplementum, 2003, Issue:65 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; Animals; Basal Ganglia; Brain Stem; Disease Models, Animal; Dopamine; Dopamine Agents; Nerve Degeneration; Neurons; Oxidopamine; Parkinson Disease; Rodentia; Rotenone; Uncoupling Agents	2003
Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell and tissue research, 2004, Volume: 318, Issue:1 Topics: Animals; Disease Models, Animal; Fungicides, Industrial; Herbicides; Maneb; Nerve Degeneration; Neurotoxins; Paraquat; Parkinson Disease; Rotenone; Uncoupling Agents	2004
Neural repair strategies for Parkinson's disease: insights from primate models. Cell transplantation, 2006, Volume: 15, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Transplantation; Deep Brain Stimulation; Disease Models, Animal; Fungicides, Industrial; Glial Cell Line-Derived Neurotrophic Factor; Herbicides; Humans; Maneb; Nerve Degeneration; Oxidopamine; Paraquat; Parkinson Disease; Pesticides; Primates; Rotenone	2006
The rotenone model of parkinsonism--the five years inspection. Journal of neural transmission. Supplementum, 2006, Issue:70 Topics: Animals; Disease Models, Animal; Dopamine; Humans; Movement; Neurodegenerative Diseases; Neurons; Parkinson Disease, Secondary; Rotenone; Substantia Nigra; tau Proteins; Uncoupling Agents	2006
Mitochondrial toxins and neurodegenerative diseases. Frontiers in bioscience : a journal and virtual library, 2007, Jan-01, Volume: 12 Topics: Animals; Disease Models, Animal; Humans; Huntington Disease; Mitochondria; MPTP Poisoning; Neurodegenerative Diseases; Nitro Compounds; Parkinson Disease, Secondary; Propionates; Rotenone; Succinate Dehydrogenase; Tetrahydroisoquinolines	2007

Trials

1 trial(s) available for rotenone and Disease Models, Animal

Article	Year
Pharmacological Modulation of the Mitochondrial Electron Transport Chain in Paclitaxel-Induced Painful Peripheral Neuropathy. The journal of pain, 2015, Volume: 16, Issue:10 Topics: Animals; Antimycin A; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Electron Transport; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Hyperalgesia; Male; Motor Activity; Paclitaxel; Pain; Pain Measurement; Peripheral Nervous System Diseases; Psychomotor Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Single-Blind Method; Time Factors	2015

Article

Year

Pharmacological Modulation of the Mitochondrial Electron Transport Chain in Paclitaxel-Induced Painful Peripheral Neuropathy.

The journal of pain, 2015, Volume: 16, Issue:10

Topics: Animals; Antimycin A; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Electron Transport; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Hyperalgesia; Male; Motor Activity; Paclitaxel; Pain; Pain Measurement; Peripheral Nervous System Diseases; Psychomotor Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Single-Blind Method; Time Factors

2015

Other Studies

339 other study(ies) available for rotenone and Disease Models, Animal

Article	Year
Inhibitors of metabolism rescue cell death in Huntington's disease models. Proceedings of the National Academy of Sciences of the United States of America, 2007, Sep-04, Volume: 104, Issue:36 Topics: Adenosine Triphosphate; Animals; Caspases; Cell Death; Cell Line; Disease Models, Animal; Drosophila melanogaster; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glycolysis; Huntington Disease; Mitochondria; Mutation; NAD; Neurons; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Rotenone; Signal Transduction	2007
Phenolic Metabolites of Dalea ornata Affect Both Survival and Motility of the Human Pathogenic Hookworm Ancylostoma ceylanicum. Journal of natural products, 2016, 09-23, Volume: 79, Issue:9 Topics: Albendazole; Ancylostoma; Ancylostomatoidea; Ancylostomiasis; Animals; Anthelmintics; Cricetinae; Disease Models, Animal; Disease Resistance; Fabaceae; Humans; Mebendazole; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenols; Plant Components, Aerial; Rosaceae; Saxifragaceae; Spleen	2016
Inhibition of natriuretic peptide receptor 1 reduces itch in mice. Science translational medicine, 2019, 07-10, Volume: 11, Issue:500 Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries	2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection	2020
The Possible Role of Oxidative medicine and cellular longevity, 2021, Volume: 2021 Topics: Animals; Bifidobacterium longum; Disease Models, Animal; Humans; Lacticaseibacillus rhamnosus; Locomotion; Oxidative Stress; Parkinson Disease; Rotenone; Zebrafish	2021
Quercetin exhibits potent antioxidant activity, restores motor and non-motor deficits induced by rotenone toxicity. PloS one, 2021, Volume: 16, Issue:11 Topics: Animals; Antioxidants; Behavior, Animal; Cognition; Cognitive Dysfunction; Depression; Disease Models, Animal; Male; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Oxidative Stress; Parkinson Disease, Secondary; Quercetin; Rats; Rats, Wistar; Rotenone; Signal Transduction; Treatment Outcome	2021
Intranasal Exposure to Low-Dose Rotenone Induced Alpha-Synuclein Accumulation and Parkinson's Like Symptoms Without Loss of Dopaminergic Neurons. Neurotoxicity research, 2022, Volume: 40, Issue:1 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Parkinson Disease; Rotenone; Substantia Nigra	2022
Neurotoxicity research, 2022, Volume: 40, Issue:1 Topics: Animals; Disease Models, Animal; Glutamates; Humans; Neuroprotective Agents; Parkinsonian Disorders; Rats; Rotenone	2022
Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models. Molecular medicine reports, 2022, Volume: 25, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Avoidance Learning; Blotting, Western; Chronic Disease; Disease Models, Animal; DNA-Binding Proteins; Dopaminergic Neurons; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Mice, Inbred C57BL; Motor Activity; Nerve Tissue Proteins; Parkinson Disease, Secondary; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2022
SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration. International journal of molecular sciences, 2022, Jan-30, Volume: 23, Issue:3 Topics: Animals; Armadillo Domain Proteins; Cells, Cultured; Cytoskeletal Proteins; Disease Models, Animal; Energy Metabolism; Female; Fibroblasts; Gene Knockout Techniques; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxygen Consumption; Primary Cell Culture; Retinal Degeneration; Retinal Ganglion Cells; Rotenone	2022
The Anxiolytic Drug Buspirone Prevents Rotenone-Induced Toxicity in a Mouse Model of Parkinson's Disease. International journal of molecular sciences, 2022, Feb-06, Volume: 23, Issue:3 Topics: Animals; Buspirone; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Pituitary Adenylate Cyclase-Activating Polypeptide; Rotenone; Vasoactive Intestinal Peptide	2022
Dihydroquercetin improves rotenone-induced Parkinsonism by regulating NF-κB-mediated inflammation pathway in rats. Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:5 Topics: Animals; Disease Models, Animal; Inflammation; Male; Neuroprotective Agents; NF-kappa B; Parkinsonian Disorders; Quercetin; Rats; Rats, Wistar; Rotenone	2022
Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson's disease. Scientific reports, 2022, 02-24, Volume: 12, Issue:1 Topics: alpha-Synuclein; Animals; Cells, Cultured; Disease Models, Animal; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Neurons; Norepinephrine; Parkinson Disease; Pars Compacta; Prodromal Symptoms; Rotenone; Small-Conductance Calcium-Activated Potassium Channels	2022
Gene therapy of yeast NDI1 on mitochondrial complex I dysfunction in rotenone-induced Parkinson's disease models in vitro and vivo. Molecular medicine (Cambridge, Mass.), 2022, 03-07, Volume: 28, Issue:1 Topics: Adenosine Triphosphate; alpha-Synuclein; Animals; Dependovirus; Disease Models, Animal; Electron Transport Complex I; Genetic Therapy; Mammals; Mice; Neurodegenerative Diseases; Parkinson Disease; Reactive Oxygen Species; Rotenone; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2022
Microglial Activation Damages Dopaminergic Neurons through MMP-2/-9-Mediated Increase of Blood-Brain Barrier Permeability in a Parkinson's Disease Mouse Model. International journal of molecular sciences, 2022, Mar-03, Volume: 23, Issue:5 Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Microglia; Parkinson Disease; Permeability; Rotenone	2022
Nanostructure lipid carriers enhance alpha-mangostin neuroprotective efficacy in mice with rotenone-induced neurodegeneration. Metabolic brain disease, 2022, Volume: 37, Issue:5 Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Lipids; Male; Mice; Mice, Inbred ICR; Nanostructures; Neuroprotective Agents; Parkinson Disease, Secondary; Rotenone; Substantia Nigra; Superoxide Dismutase; Tissue Distribution; Tyrosine 3-Monooxygenase; Xanthones	2022
The Anti-Parkinson Potential of Gingko biloba-Supplement Mitigates Cortico-Cerebellar Degeneration and Neuropathobiological Alterations via Inflammatory and Apoptotic Mediators in Mice. Neurochemical research, 2022, Volume: 47, Issue:8 Topics: Animals; Apoptosis; Disease Models, Animal; Dopamine; Ginkgo biloba; Mice; Neurodegenerative Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Parkinson Disease; Plant Preparations; Rotenone	2022
Ginkgo biloba protects striatal neurodegeneration and gut phagoinflammatory damage in rotenone-induced mice model of Parkinson's disease: Role of executioner caspase-3/Nrf2/ARE signaling. Journal of food biochemistry, 2022, Volume: 46, Issue:9 Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Dopamine; Ginkgo biloba; Mice; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Parkinson Disease; Rotenone	2022
Trehalose ameliorates prodromal non-motor deficits and aberrant protein accumulation in a rotenone-induced mouse model of Parkinson's disease. Archives of pharmacal research, 2022, Volume: 45, Issue:6 Topics: Animals; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Olfaction Disorders; Parkinson Disease; Prodromal Symptoms; Rotenone; Trehalose; Tyrosine 3-Monooxygenase	2022
Neuroprotective Effects of Cranberry Juice Treatment in a Rat Model of Parkinson's Disease. Nutrients, 2022, May-11, Volume: 14, Issue:10 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Fruit and Vegetable Juices; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Vaccinium macrocarpon	2022
Morin ameliorates rotenone-induced Parkinson disease in mice through antioxidation and anti-neuroinflammation: gut-brain axis involvement. Brain research, 2022, 08-15, Volume: 1789 Topics: Acetylcholinesterase; Animals; Antioxidants; Brain-Gut Axis; Disease Models, Animal; Flavonoids; Glutathione; Male; Mice; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rotenone	2022
Brain polar phenol content, behavioural and neurochemical effects of Corinthian currant in a rotenone rat model of Parkinson's disease. Nutritional neuroscience, 2023, Volume: 26, Issue:7 Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopaminergic Neurons; Neuroprotective Agents; Parkinson Disease; Phenol; Rats; Ribes; Rotenone; Substantia Nigra	2023
Bioinformatics guided rotenone adjuvant kindling in mice as a new animal model of drug-resistant epilepsy. Computers in biology and medicine, 2022, Volume: 147 Topics: Animals; Anticonvulsants; Computational Biology; Disease Models, Animal; Epilepsy; Lamotrigine; Mice; Proteomics; Rotenone	2022
Neuroprotective effect of quercetin against rotenone-induced neuroinflammation and alterations in mice behavior. Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Dopamine; Mice; Neuroinflammatory Diseases; Neuroprotective Agents; Parkinson Disease; Pesticides; Quercetin; Rotenone	2022
Taste Impairments in a Parkinson's Disease Model Featuring Intranasal Rotenone Administration in Mice. Journal of Parkinson's disease, 2022, Volume: 12, Issue:6 Topics: Administration, Intranasal; Animals; Disease Models, Animal; Mice; Olfaction Disorders; Parkinson Disease; Rotenone; Taste; Tyrosine 3-Monooxygenase	2022
Metformin improves depressive-like behavior in experimental Parkinson's disease by inducing autophagy in the substantia nigra and hippocampus. Inflammopharmacology, 2022, Volume: 30, Issue:5 Topics: Animals; Antidepressive Agents; Autophagy; Disease Models, Animal; Hippocampus; Hypoglycemic Agents; Male; Metformin; Mice; Mice, Inbred C57BL; Parkinson Disease; Quality of Life; Rotenone; Substantia Nigra; Sucrose; Transcription Factors	2022
Neuroprotective effect of anethole against rotenone induced non-motor deficits and oxidative stress in rat model of Parkinson's disease. Behavioural brain research, 2023, 02-02, Volume: 437 Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Male; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Superoxide Dismutase	2023
Fenofibrate promotes neuroprotection in a model of rotenone-induced Parkinson's disease. Behavioural pharmacology, 2022, 12-01, Volume: 33, Issue:8 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Fenofibrate; Male; Neurodegenerative Diseases; Neuroprotection; Neuroprotective Agents; Parkinson Disease; Peroxisome Proliferator-Activated Receptors; Rats; Rotenone; Substantia Nigra	2022
Dopamine Release Impairments Accompany Locomotor and Cognitive Deficiencies in Rotenone-Treated Parkinson's Disease Model Zebrafish. Chemical research in toxicology, 2022, 11-21, Volume: 35, Issue:11 Topics: Animals; Cognition; Disease Models, Animal; Dopamine; Parkinson Disease; Rotenone; Zebrafish	2022
Non-Reproducibility of Oral Rotenone as a Model for Parkinson's Disease in Mice. International journal of molecular sciences, 2022, Oct-21, Volume: 23, Issue:20 Topics: alpha-Synuclein; Animals; Body Weight; Chromatography, Liquid; Disease Models, Animal; Mice; Mice, Inbred C57BL; Parkinson Disease; Parkinsonian Disorders; Rotenone; Substantia Nigra; Tandem Mass Spectrometry	2022
Benefits of p-coumaric acid in mice with rotenone-induced neurodegeneration. Metabolic brain disease, 2023, Volume: 38, Issue:1 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Male; Malondialdehyde; Mice; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rotenone; Tumor Necrosis Factor-alpha	2023
Europinidin Inhibits Rotenone-Activated Parkinson's Disease in Rodents by Decreasing Lipid Peroxidation and Inflammatory Cytokines Pathways. Molecules (Basel, Switzerland), 2022, Oct-23, Volume: 27, Issue:21 Topics: Animals; Cytokines; Disease Models, Animal; Dopamine; Lipid Peroxidation; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rodentia; Rotenone	2022
Rotenone induced olfactory deficit in Parkinson's disease rat model: The protective role of adenosine A Journal of chemical neuroanatomy, 2023, Volume: 127 Topics: Animals; Brain; Caffeine; Disease Models, Animal; Male; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Wistar; Rotenone	2023
The Mechanism of SNHG8/Microrna-421-3p/Sorting Nexin 8 Axis on Dopaminergic Neurons in Substantia Nigra in a Mouse Model of Parkinson's Disease. Neurochemical research, 2023, Volume: 48, Issue:3 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; MicroRNAs; Neurodegenerative Diseases; Parkinson Disease; Rotenone; Sorting Nexins; Substantia Nigra	2023
Neuroprotective potential of cinnamoyl derivatives against Parkinson's disease indicators in Drosophila melanogaster and in silico models. Neurotoxicology, 2023, Volume: 94 Topics: Animals; Computer Simulation; Disease Models, Animal; Drosophila melanogaster; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rotenone	2023
Correlation between α-synuclein and fatty acid composition in jejunum of rotenone-treated mice is dependent on acyl chain length. General physiology and biophysics, 2022, Volume: 41, Issue:6 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Fatty Acids; Jejunum; Mice; Parkinson Disease; Rotenone	2022
Protective effects of evening primrose oil on behavioral activities, nigral microglia and histopathological changes in a rat model of rotenone-induced parkinsonism. Journal of chemical neuroanatomy, 2023, Volume: 127 Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dopamine; Male; Microglia; Neuroprotective Agents; Parkinson Disease; Parkinsonian Disorders; Rats; Rotenone	2023
Folic Acid and Vitamin B12 Prevent Deleterious Effects of Rotenone on Object Novelty Recognition Memory and Genes, 2022, 12-17, Volume: 13, Issue:12 Topics: Animals; Disease Models, Animal; Folic Acid; Parkinson Disease; Rats; Rotenone; Vitamin B 12	2022
Identification of molecular network of gut-brain axis associated with neuroprotective effects of PPARδ-ligand erucic acid in rotenone-induced Parkinson's disease model in zebrafish. The European journal of neuroscience, 2023, Volume: 57, Issue:4 Topics: Acetylcholinesterase; Animals; Brain-Gut Axis; Chromatography, Liquid; Disease Models, Animal; Erucic Acids; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Ligands; Neuroprotective Agents; Parkinson Disease; PPAR delta; Rotenone; Tandem Mass Spectrometry; Zebrafish; Zebrafish Proteins	2023
Intranasal Rotenone Induces Alpha-Synuclein Accumulation, Neuroinflammation and Dopaminergic Neurodegeneration in Middle-Aged Mice. Neurochemical research, 2023, Volume: 48, Issue:5 Topics: alpha-Synuclein; Animals; Brain; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Female; Mice; Neuroinflammatory Diseases; Parkinson Disease; Rotenone	2023
Protective Effects of Currants ( International journal of molecular sciences, 2022, Dec-27, Volume: 24, Issue:1 Topics: Animals; Antioxidants; Anxiety; Comorbidity; Disease Models, Animal; Dopaminergic Neurons; Neuroprotective Agents; Parkinson Disease; Rats; Ribes; Rotenone; Serotonin; Vitis	2022
The effects of gallic acid and vagotomy on motor function, intestinal transit, brain electrophysiology and oxidative stress alterations in a rat model of Parkinson's disease induced by rotenone. Life sciences, 2023, Feb-15, Volume: 315 Topics: Animals; Brain; Disease Models, Animal; Electrophysiology; Gallic Acid; Male; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Vagotomy	2023
Neuroprotective Effect of Propolis Polyphenol-Based Nanosheets in Cellular and Animal Models of Rotenone-Induced Parkinson's Disease. ACS chemical neuroscience, 2023, 03-01, Volume: 14, Issue:5 Topics: Animals; Antioxidants; Disease Models, Animal; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Polyphenols; Propolis; Rotenone	2023
Investigation of the pharmacological, behavioral, and biochemical effects of boron in parkinson-indicated rats. Cellular and molecular biology (Noisy-le-Grand, France), 2022, Aug-31, Volume: 68, Issue:8 Topics: Animals; Antioxidants; Boron; Disease Models, Animal; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Wistar; Rotenone	2022
Impact of age on the rotenone-induced sporadic Parkinson's disease model using Drosophila melanogaster. Neuroscience letters, 2023, 05-14, Volume: 805 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Drosophila; Drosophila melanogaster; Male; Parkinson Disease; Rotenone	2023
β-carotene-loaded nanoparticles protect against neuromotor damage, oxidative stress, and dopamine deficits in a model of Parkinson's disease in Drosophila melanogaster. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2023, Volume: 268 Topics: Acetylcholinesterase; Animals; Antioxidants; beta Carotene; Disease Models, Animal; Dopamine; Drosophila melanogaster; Nanoparticles; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; Rotenone; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2023
Vinpocetine prevents rotenone-induced Parkinson disease motor and non-motor symptoms through attenuation of oxidative stress, neuroinflammation and α-synuclein expressions in rats. Neurotoxicology, 2023, Volume: 96 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Male; Neurodegenerative Diseases; Neuroinflammatory Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone	2023
Metabolic dysfunctions in the intranigral rotenone model of Parkinson's disease. Experimental brain research, 2023, Volume: 241, Issue:5 Topics: Animals; Cholesterol; Disease Models, Animal; Dopaminergic Neurons; Male; Neurodegenerative Diseases; Parkinson Disease; Rats; Rats, Wistar; Rotenone	2023
HCH6-1, an antagonist of formyl peptide receptor-1, exerts anti-neuroinflammatory and neuroprotective effects in cellular and animal models of Parkinson's disease. Biochemical pharmacology, 2023, Volume: 212 Topics: Animals; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Humans; Inflammasomes; Interleukin-6; Mice; Microglia; Neuroblastoma; Neuroinflammatory Diseases; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; Receptors, Formyl Peptide; Rotenone; Tumor Necrosis Factor-alpha; Zebrafish	2023
Neuroprotective Effects of International journal of molecular sciences, 2023, Apr-05, Volume: 24, Issue:7 Topics: Animals; Disease Models, Animal; Gastrointestinal Microbiome; Lactobacillus plantarum; Mice; Mice, Inbred C57BL; MicroRNAs; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Rotenone	2023
NLRP3 mediates the neuroprotective effects of SVHRSP derived from scorpion venom in rotenone-induced experimental Parkinson's disease model. Journal of ethnopharmacology, 2023, Aug-10, Volume: 312 Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Inflammasomes; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; Rotenone; Scorpion Venoms	2023
A novel protective modality against rotenone-induced Parkinson's disease: A pre-clinical study with dulaglutide. International immunopharmacology, 2023, Volume: 119 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Mice; Neuroprotective Agents; Parkinson Disease; Rats; Rotenone	2023
Anti-inflammatory, anti-apoptotic, and neuroprotective potentials of anethole in Parkinson's disease-like motor and non-motor symptoms induced by rotenone in rats. Metabolic brain disease, 2023, Volume: 38, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Neuroprotective Agents; Parkinson Disease; Rats; Rotenone	2023
Dimethyl fumarate ameliorates parkinsonian pathology by modulating autophagy and apoptosis via Nrf2-TIGAR-LAMP2/Cathepsin D axis. Brain research, 2023, 09-15, Volume: 1815 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cathepsin D; Dimethyl Fumarate; Disease Models, Animal; Mice; NF-E2-Related Factor 2; Phosphoric Monoester Hydrolases; Rotenone	2023
Beneficial role of rosemary extract on oxidative stress-mediated neuronal apoptosis in rotenone-induced attention deficit hyperactivity disease in juvenile rat model. Acta bio-medica : Atenei Parmensis, 2023, 06-14, Volume: 94, Issue:3 Topics: Animals; Apoptosis; Disease Models, Animal; Inflammation; Neurons; Olive Oil; Oxidative Stress; Rats; Rosmarinus; Rotenone	2023
Lapatinib ditosylate rescues motor deficits in rotenone-intoxicated rats: Potential repurposing of anti-cancer drug as a disease-modifying agent in Parkinson's disease. European journal of pharmacology, 2023, Sep-05, Volume: 954 Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Dopaminergic Neurons; Drug Repositioning; Lapatinib; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rotenone	2023
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease. Journal of chemical neuroanatomy, 2023, Volume: 132 Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Lacosamide; Male; Malondialdehyde; Mice; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Tumor Necrosis Factor-alpha	2023
Caffeine alleviates anxiety-like behavior and brainstem lesions in a rotenone-induced rat model of Parkinson's disease. Journal of chemical neuroanatomy, 2023, Volume: 132 Topics: Animals; Anxiety; Caffeine; Disease Models, Animal; Dopamine; Male; Mesencephalon; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Parkinson Disease; Rats; Rats, Wistar; Rotenone	2023
Effects of ozone treatment to the levels of neurodegeneration biomarkers after rotenone induced rat model of Parkinson's disease. Neuroscience letters, 2023, 09-25, Volume: 814 Topics: alpha-Synuclein; Animals; Dimethyl Sulfoxide; Disease Models, Animal; Humans; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2023
Naringenin, a Functional Food Component, Improves Motor and Non-Motor Symptoms in Animal Model of Parkinsonism Induced by Rotenone. Plant foods for human nutrition (Dordrecht, Netherlands), 2023, Volume: 78, Issue:4 Topics: Animals; Antioxidants; Disease Models, Animal; Functional Food; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats; Rotenone	2023
The identification of cianidanol as a selective estrogen receptor beta agonist and evaluation of its neuroprotective effects on Parkinson's disease models. Life sciences, 2023, Nov-15, Volume: 333 Topics: Animals; Catechin; Disease Models, Animal; Estrogen Receptor beta; Estrogens; Humans; Neuroblastoma; Neuroprotective Agents; Parkinson Disease; Rats; Rotenone	2023
Sericin alleviates motor dysfunction by modulating inflammation and TrkB/BDNF signaling pathway in the rotenone-induced Parkinson's disease model. BMC pharmacology & toxicology, 2023, 11-07, Volume: 24, Issue:1 Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Catalase; Disease Models, Animal; Inflammation; Interleukin-6; Male; Neuroprotective Agents; Parkinson Disease; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Rotenone; Sericins; Signal Transduction; Tumor Necrosis Factor-alpha	2023
Anethole attenuates motor dysfunctions, striatal neuronal activity deficiency and blood brain barrier permeability by decreasing striatal α-synuclein and oxidative stress in rotenone-induced Parkinson's disease of male rats. PloS one, 2023, Volume: 18, Issue:11 Topics: alpha-Synuclein; Animals; Antioxidants; Blood-Brain Barrier; Disease Models, Animal; Monoamine Oxidase; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Superoxide Dismutase; Weight Loss	2023
Hypoxia-inducible factor 1 alpha and nuclear-related receptor 1 as targets for neuroprotection by albendazole in a rat rotenone model of Parkinson's disease. Clinical and experimental pharmacology & physiology, 2019, Volume: 46, Issue:12 Topics: Albendazole; Animals; Behavior, Animal; Cell Death; Cell Survival; Disease Models, Animal; Dopaminergic Neurons; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Molecular Targeted Therapy; Neuroprotection; Neuroprotective Agents; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotenone	2019
Protective role of cinnabar and realgar in Hua-Feng-Dan against LPS plus rotenone-induced neurotoxicity and disturbance of gut microbiota in rats. Journal of ethnopharmacology, 2020, Jan-30, Volume: 247 Topics: Animals; Arsenicals; Disease Models, Animal; DNA, Bacterial; Dopaminergic Neurons; Drugs, Chinese Herbal; Enterobacteriaceae; Ethnopharmacology; Gastrointestinal Microbiome; Humans; Inflammation Mediators; Lactobacillaceae; Lipopolysaccharides; Male; Mercury Compounds; Microglia; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; RNA, Ribosomal, 16S; Rotenone; Sulfides; Verrucomicrobia	2020
Dopaminergic neuron injury in Parkinson's disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway. Aging, 2019, 11-04, Volume: 11, Issue:21 Topics: alpha-Synuclein; Animals; Cell Line; Disease Models, Animal; Dopaminergic Neurons; Intracellular Signaling Peptides and Proteins; Mice, Inbred C57BL; MicroRNAs; Nerve Tissue Proteins; Parkinson Disease, Secondary; RNA, Long Noncoding; Rotenone	2019
Neuroprotective effects of mitoquinone and oleandrin on Parkinson's disease model in zebrafish. The International journal of neuroscience, 2020, Volume: 130, Issue:6 Topics: Animals; Cardenolides; Disease Models, Animal; Female; Fish Proteins; Gene Expression; Locomotion; Male; Mitochondria; Neuroprotective Agents; Organophosphorus Compounds; Parkinson Disease; Parkinsonian Disorders; Rotenone; Synucleins; Ubiquinone; Zebrafish	2020
Protective Effect of (-)Epigallocatechin-3-gallate on Rotenone-Induced Parkinsonism-like Symptoms in Rats. Neurotoxicity research, 2020, Volume: 37, Issue:3 Topics: Animals; Apoptosis; Behavior, Animal; Catechin; Corpus Striatum; Disease Models, Animal; Encephalitis; Inflammation Mediators; Male; Neuroprotective Agents; Parkinsonian Disorders; Rats, Wistar; Rotenone	2020
miR-185 and SEPT5 Genes May Contribute to Parkinson's Disease Pathophysiology. Oxidative medicine and cellular longevity, 2019, Volume: 2019 Topics: Aged; Animals; Cell Cycle Proteins; Cell Line, Tumor; Corpus Striatum; Disease Models, Animal; Gene Expression; Humans; Male; MicroRNAs; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Septins; Substantia Nigra; Transfection	2019
Potential therapeutic effects of antagonizing adenosine A Molecular and cellular biochemistry, 2020, Volume: 465, Issue:1-2 Topics: Adenosine A2 Receptor Antagonists; Animals; Curcumin; Disease Models, Animal; Hippocampus; Humans; Male; Mice; Neuroprotective Agents; Niacin; Parkinson Disease, Secondary; Receptor, Adenosine A2A; Rotenone; Substantia Nigra	2020
Neuroprotective effects of Bacopa monnieri in Parkinson's disease model. Metabolic brain disease, 2020, Volume: 35, Issue:3 Topics: alpha-Synuclein; Animals; Bacopa; Cerebral Cortex; Chemokine CCL4; Disease Models, Animal; Hippocampus; Interleukin-1beta; Interleukin-6; Male; Neuroprotective Agents; Oxidative Stress; Parkinson Disease, Secondary; Plant Extracts; Rats; Rats, Wistar; Reactive Oxygen Species; Rotenone; Substantia Nigra; Tumor Necrosis Factor-alpha	2020
Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis. Cells, 2019, 12-19, Volume: 9, Issue:1 Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA Damage; Dopaminergic Neurons; Drug Synergism; Gene Knockdown Techniques; Humans; Male; Parkinson Disease; Peroxiredoxins; Primary Cell Culture; Rats; Rotenone; Signal Transduction; Tumor Suppressor Protein p53; Tumor Suppressor Proteins	2019
Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease. The Journal of biological chemistry, 2020, 03-13, Volume: 295, Issue:11 Topics: Actin Cytoskeleton; alpha-Synuclein; Amyloid; Animals; Apoptosis; Cell Death; Cell Line, Tumor; Computer Simulation; Cytoskeleton; Deubiquitinating Enzymes; Disease Models, Animal; Endocytosis; Male; Mice, Inbred C57BL; Mitochondria; Models, Biological; Nanostructures; Neurons; Neurotoxins; Oxidation-Reduction; Parkinson Disease; Phosphoserine; Protein Aggregates; Protein Multimerization; Reactive Oxygen Species; Rotenone	2020
Neuroprotective effects of Danshensu on rotenone-induced Parkinson's disease models in vitro and in vivo. BMC complementary medicine and therapies, 2020, Jan-23, Volume: 20, Issue:1 Topics: Animals; Blotting, Western; Cell Line, Tumor; Disease Models, Animal; Flow Cytometry; Humans; Lactates; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Rotarod Performance Test; Rotenone	2020
Troxerutin downregulates C/EBP-β gene expression via modulating the IFNγ-ERK1/2 signaling pathway to ameliorate rotenone-induced retinal neurodegeneration. Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:6 Topics: Animals; CCAAT-Enhancer-Binding Protein-beta; Disease Models, Animal; Down-Regulation; Gene Expression; Hydroxyethylrutoside; Interferon-gamma; Male; MAP Kinase Signaling System; Neurodegenerative Diseases; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Retinal Diseases; RNA, Messenger; Rotenone; Tumor Necrosis Factor-alpha	2020
Protective effect of metformin against rotenone-induced parkinsonism in mice. Toxicology mechanisms and methods, 2020, Volume: 30, Issue:5 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Inflammation; Interleukin-1beta; Male; Metformin; Mice; Mice, Inbred C57BL; Microglia; Parkinson Disease, Secondary; Protective Agents; Rotenone; Tumor Necrosis Factor-alpha	2020
Oral Supplements of Current pharmaceutical biotechnology, 2020, Volume: 21, Issue:12 Topics: Administration, Oral; Animals; Antioxidants; Brain; Cytokines; Dietary Supplements; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Ginkgo biloba; Glutathione; Lipid Peroxidation; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Parkinson Disease; Plant Extracts; Random Allocation; Rats; Rotenone; Superoxide Dismutase	2020
Chronic Systemic Exposure to Low-Dose Rotenone Induced Central and Peripheral Neuropathology and Motor Deficits in Mice: Reproducible Animal Model of Parkinson's Disease. International journal of molecular sciences, 2020, May-04, Volume: 21, Issue:9 Topics: alpha-Synuclein; Animals; Behavior, Animal; Biomarkers; Cholinergic Neurons; Disease Models, Animal; Dopaminergic Neurons; Electron Transport Complex I; Environmental Exposure; Fluorescent Antibody Technique; Insecticides; Male; Mice; Mitochondria; Motor Disorders; Myenteric Plexus; Nervous System Diseases; Parkinson Disease; Rotenone; Substantia Nigra	2020
Coordinated Action of miR-146a and Parkin Gene Regulate Rotenone-induced Neurodegeneration. Toxicological sciences : an official journal of the Society of Toxicology, 2020, 08-01, Volume: 176, Issue:2 Topics: Animals; Disease Models, Animal; MicroRNAs; Mitochondria; Mitophagy; NF-kappa B; Parkinson Disease, Secondary; Rats; Rotenone; Ubiquitin-Protein Ligases	2020
Monascin exhibits neuroprotective effects in rotenone model of Parkinson's disease via antioxidation and anti-neuroinflammation. Neuroreport, 2020, 06-07, Volume: 31, Issue:9 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Encephalitis; Heterocyclic Compounds, 3-Ring; Male; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Rats, Sprague-Dawley; Rotenone	2020
Long noncoding RNA GAS5 promotes microglial inflammatory response in Parkinson's disease by regulating NLRP3 pathway through sponging miR-223-3p. International immunopharmacology, 2020, Volume: 85 Topics: Animals; Behavior, Animal; Binding Sites; Cell Line; Computational Biology; Disease Models, Animal; Down-Regulation; Gene Knockdown Techniques; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Male; Mice, Inbred C57BL; Microglia; MicroRNAs; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; RNA, Long Noncoding; Rotenone; Substantia Nigra; Tumor Necrosis Factor-alpha; Up-Regulation	2020
Neuroprotective action of agmatine in rotenone-induced model of Parkinson's disease: Role of BDNF/cREB and ERK pathway. Behavioural brain research, 2020, 08-17, Volume: 392 Topics: Agmatine; Animals; Apoptosis; Brain; Brain-Derived Neurotrophic Factor; Cell Survival; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Male; MAP Kinase Signaling System; Neuronal Plasticity; Neurons; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Signal Transduction	2020
Healthspan Enhancement by Olive Polyphenols in International journal of molecular sciences, 2020, May-29, Volume: 21, Issue:11 Topics: Aging; alpha-Synuclein; Animals; Animals, Genetically Modified; Biomarkers; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Diet, Mediterranean; Disease Models, Animal; Dopaminergic Neurons; Humans; Longevity; Microscopy, Fluorescence; Olea; Olive Oil; Parkinson Disease; Polyphenols; Rotenone	2020
Amelioration of motor and non-motor deficits and increased striatal APoE levels highlight the beneficial role of pistachio supplementation in rotenone-induced rat model of PD. Metabolic brain disease, 2020, Volume: 35, Issue:7 Topics: Animals; Apolipoproteins E; Corpus Striatum; Disease Models, Animal; Motor Skills; Neuroprotective Agents; Oxidative Stress; Parkinson Disease, Secondary; Pistacia; Plant Extracts; Rats; Rotenone	2020
Editorial for the Special Issue "Animal Models of Parkinson's Disease and Related Disorders". International journal of molecular sciences, 2020, Jun-15, Volume: 21, Issue:12 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Early Diagnosis; Humans; Lewy Body Disease; Oxidopamine; Parkinson Disease; Rotenone	2020
Comparative study between bone marrow mesenchymal stem cell and their conditioned medium in the treatment of rat model of Parkinsonism. Journal of cellular physiology, 2021, Volume: 236, Issue:1 Topics: Animals; Bone Marrow Cells; Cells, Cultured; Culture Media, Conditioned; Disease Models, Animal; Dopaminergic Neurons; Glial Fibrillary Acidic Protein; Male; Mesencephalon; Mesenchymal Stem Cells; Nestin; Neuropil; Parkinsonian Disorders; Rats; Rotenone; Stem Cells; Substantia Nigra; Synucleins	2021
Enhanced oral bioavailability and neuroprotective effect of fisetin through its SNEDDS against rotenone-induced Parkinson's disease rat model. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 144 Topics: Administration, Oral; Animals; Biological Availability; Disease Models, Animal; Female; Flavonols; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone	2020
Neuroprotection of Rotenone-Induced Parkinsonism by Ursolic Acid in PD Mouse Model. CNS & neurological disorders drug targets, 2020, Volume: 19, Issue:7 Topics: alpha-Synuclein; Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Disease Models, Animal; Dopaminergic Neurons; Male; Mice; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Rotenone; Triterpenes; Ursolic Acid	2020
Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models. Scientific reports, 2020, 08-25, Volume: 10, Issue:1 Topics: Animals; Apoptosis; Brain Ischemia; Cell Line, Tumor; Cyclic N-Oxides; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Glucose; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Neuroblastoma; Neurons; Neuroprotection; Neuroprotective Agents; Nitrogen Oxides; Oligomycins; Oxygen; Rotenone	2020
Immunoproteasome is up-regulated in rotenone-induced Parkinson's disease rat model. Neuroscience letters, 2020, 11-01, Volume: 738 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Male; Microglia; Parkinson Disease; Proteasome Endopeptidase Complex; Rats, Wistar; Rotenone; Substantia Nigra; Up-Regulation	2020
Ameliorative effects of flavonoids and polyketides on the rotenone induced Drosophila model of Parkinson's disease. Neurotoxicology, 2020, Volume: 81 Topics: Animals; Antioxidants; Antiparkinson Agents; Behavior, Animal; Brain; Catalase; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Flavonoids; Gene Expression Regulation, Enzymologic; Lipid Peroxidation; Locomotion; Oxidative Stress; Parkinsonian Disorders; Polyketides; Rotenone; Superoxide Dismutase	2020
Role of caloric vestibular stimulation in improvement of motor symptoms and inhibition of neuronal degeneration in rotenone model of Parkinson's disease - An experimental study. Physiology international, 2020, Oct-17, Volume: 107, Issue:3 Topics: Animals; Disease Models, Animal; Male; Parkinson Disease; Rats; Rats, Wistar; Reproducibility of Results; Rotenone; Substantia Nigra	2020
Changes in COX histochemistry in the brain of mice and rats exposed to chronic subcutaneous rotenone. Journal of chemical neuroanatomy, 2020, Volume: 110 Topics: Animals; Brain; Disease Models, Animal; Dopamine; Electron Transport Complex IV; Mice; Mitochondria; Neurons; Parkinson Disease, Secondary; Rats; Rotenone	2020
Cerebral and cerebellar histological changes in the rat animal model of rotenone induced parkinsonism can be ameliorated by bone marrow derived stem cell conditioned media. Journal of chemical neuroanatomy, 2021, Volume: 111 Topics: Animals; Behavior, Animal; Cerebellum; Cerebral Cortex; Culture Media, Conditioned; Disease Models, Animal; Mesenchymal Stem Cells; Motor Activity; Parkinson Disease, Secondary; Rats; Rotenone	2021
Contribution of DHA diols (19,20-DHDP) produced by cytochrome P450s and soluble epoxide hydrolase to the beneficial effects of DHA supplementation in the brains of rotenone-induced rat models of Parkinson's disease. Biochimica et biophysica acta. Molecular and cell biology of lipids, 2021, Volume: 1866, Issue:2 Topics: Animals; Brain; Catalase; Cytochrome P-450 Enzyme System; Disease Models, Animal; Docosahexaenoic Acids; Epoxide Hydrolases; Fatty Acids, Unsaturated; Humans; Male; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidation-Reduction; Parkinson Disease, Secondary; Rats; Rotenone; Superoxide Dismutase-1	2021
Hexane extract from SpoSndias mombin L. (Anacardiaceae) prevents behavioral and oxidative status changes on model of Parkinson's disease in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2021, Volume: 241 Topics: Anacardiaceae; Animals; Behavior, Animal; Disease Models, Animal; Lipid Peroxidation; Oxidative Stress; Parkinson Disease, Secondary; Plant Extracts; Rotenone; Zebrafish	2021
Recuperative effect of estrogen on rotenone-induced experimental model of Parkinson's disease in rats. Environmental science and pollution research international, 2021, Volume: 28, Issue:17 Topics: Animals; Disease Models, Animal; Estrogens; Female; Humans; Parkinson Disease; Rats; Rats, Wistar; Rotenone	2021
Role of gut microbiota in regulating gastrointestinal dysfunction and motor symptoms in a mouse model of Parkinson's disease. Gut microbes, 2021, 01-01, Volume: 13, Issue:1 Topics: Animals; Brain-Gut Axis; Disease Models, Animal; Dysbiosis; Dystonic Disorders; Female; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Tract; Germ-Free Life; Male; Mice; Parkinson Disease; Rotenone; Tight Junctions; Tyrosine 3-Monooxygenase	2021
Pharmacological validation of TDO as a target for Parkinson's disease. The FEBS journal, 2021, Volume: 288, Issue:14 Topics: Animals; Brain; Cognition; Disease Models, Animal; Enzyme Inhibitors; Insecticides; Male; Mice; Mice, Inbred C57BL; Motor Activity; Parkinson Disease; Rotenone; Small Molecule Libraries; Tryptophan Oxygenase	2021
The Beneficial Effect of Rice Bran Extract Against Rotenone-Induced Experimental Parkinson's Disease in Rats. Current molecular pharmacology, 2021, Volume: 14, Issue:3 Topics: Animals; Disease Models, Animal; Oryza; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Rats; Rotenone	2021
Can Cranberry Juice Protect against Rotenone-Induced Toxicity in Rats? Nutrients, 2021, Mar-24, Volume: 13, Issue:4 Topics: Animals; Antioxidants; Brain Diseases; Disease Models, Animal; DNA Damage; Fruit and Vegetable Juices; Kidney Diseases; Liver Diseases; Male; Oxidative Stress; Rats; Rats, Wistar; Rotenone; Uncoupling Agents; Vaccinium macrocarpon	2021
The association of enteric neuropathy with gut phenotypes in acute and progressive models of Parkinson's disease. Scientific reports, 2021, 04-12, Volume: 11, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acute Disease; Animals; Cell Count; Chronic Disease; Colon; Disease Models, Animal; Feces; Ganglia; Gastrointestinal Tract; Intestinal Pseudo-Obstruction; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nitric Oxide Synthase Type I; Oxidopamine; Parkinson Disease; Phenotype; Rotenone	2021
The dynamics of nigrostriatal system damage and neurobehavioral changes in the rotenone rat model of Parkinson's disease. Brain research bulletin, 2021, Volume: 173 Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Eating; Hand Strength; Male; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotenone; Substantia Nigra	2021
Pharmacological evaluation of vanillic acid in rotenone-induced Parkinson's disease rat model. European journal of pharmacology, 2021, Jul-15, Volume: 903 Topics: Animals; Antioxidants; Antiparkinson Agents; Behavior, Animal; Body Weight; Carbidopa; Catalase; Catalepsy; Disease Models, Animal; Dopamine; Drug Combinations; Female; Glutathione; Levodopa; Locomotion; Male; Mesencephalon; Muscular Diseases; Oxidative Stress; Parkinson Disease; Postural Balance; Rats, Sprague-Dawley; Rotenone; Superoxides; Thiobarbituric Acid Reactive Substances; Vanillic Acid	2021
Microemulsion-based gel for the transdermal delivery of rasagiline mesylate: In vitro and in vivo assessment for Parkinson's therapy. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 165 Topics: Administration, Cutaneous; Administration, Oral; Animals; Biological Availability; Disease Models, Animal; Emulsions; Feasibility Studies; Humans; Hydrogels; Indans; Locomotion; Male; Monoamine Oxidase Inhibitors; Parkinson Disease, Secondary; Rabbits; Rats; Rotenone; Skin; Skin Tests	2021
Parkinsonism-like Disease Induced by Rotenone in Rats: Treatment Role of Curcumin, Dopamine Agonist and Adenosine A Current aging science, 2022, 02-03, Volume: 15, Issue:1 Topics: Adenosine; Aged; Animals; Curcumin; Disease Models, Animal; Dopamine Agonists; Humans; Inflammation Mediators; Mice; Neuroprotective Agents; Parkinson Disease; Parkinsonian Disorders; Rats; Receptor, Adenosine A2A; Rotenone	2022
Generation of Mitochondrial Toxin Rodent Models of Parkinson's Disease Using 6-OHDA , MPTP , and Rotenone. Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2322 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopamine; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neurotoxins; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Rodentia; Rotenone	2021
Effect of lobeglitazone on motor function in rat model of Parkinson's disease with diabetes co-morbidity. Brain research bulletin, 2021, Volume: 173 Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Hypoglycemic Agents; Male; Motor Activity; Motor Skills; Parkinson Disease, Secondary; Pyrimidines; Rats; Rats, Wistar; Rotenone; Thiazolidinediones	2021
Baicalein alleviates depression-like behavior in rotenone- induced Parkinson's disease model in mice through activating the BDNF/TrkB/CREB pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 140 Topics: Animals; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Depression; Disease Models, Animal; Flavanones; Flavonoids; Homeostasis; Inflammation; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neuroprotective Agents; Neurotransmitter Agents; Parkinson Disease; Protein-Tyrosine Kinases; Rotenone; Signal Transduction	2021
Haloperidol rescues the schizophrenia-like phenotype in adulthood after rotenone administration in neonatal rats. Psychopharmacology, 2021, Volume: 238, Issue:9 Topics: Animals; Animals, Newborn; Disease Models, Animal; Haloperidol; Phenotype; Rats; Rotenone; Schizophrenia	2021
Tryptophan in the diet ameliorates motor deficits in a rotenone-induced rat Parkinson's disease model via activating the aromatic hydrocarbon receptor pathway. Brain and behavior, 2021, Volume: 11, Issue:8 Topics: Animals; Diet; Disease Models, Animal; Hydrocarbons, Aromatic; Neuroprotective Agents; Parkinson Disease; Rats; Rotenone; Tryptophan	2021
Caprylic acid ameliorates rotenone induced inflammation and oxidative stress in the gut-brain axis in Zebrafish. Molecular biology reports, 2021, Volume: 48, Issue:6 Topics: Animals; Brain; Brain-Gut Axis; Caprylates; Disease Models, Animal; Gastrointestinal Tract; Glutathione; Inflammation; Lipid Peroxidation; Oxidative Stress; Parkinson Disease; Rotenone; Superoxide Dismutase; Zebrafish; Zebrafish Proteins	2021
UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson's disease mice after oral administration of Wen-Shen-Yang-Gan decoction. Aging, 2021, 08-02, Volume: 13, Issue:15 Topics: Administration, Oral; Animals; Antiparkinson Agents; Cheminformatics; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopaminergic Neurons; Male; Metabolomics; Mice; Mice, Inbred C57BL; Multivariate Analysis; Neuroprotective Agents; Parkinson Disease; Plant Extracts; Rotenone; Substantia Nigra; Tandem Mass Spectrometry	2021
Involvement of endoplasmic reticulum stress in rotenone-induced leber hereditary optic neuropathy model and the discovery of new therapeutic agents. Journal of pharmacological sciences, 2021, Volume: 147, Issue:2 Topics: Aniline Compounds; Animals; Cells, Cultured; Disease Models, Animal; DNA, Mitochondrial; Drug Discovery; Drug Evaluation, Preclinical; Endoplasmic Reticulum Stress; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Molecular Targeted Therapy; Mutation; Optic Atrophy, Hereditary, Leber; Piperazines; Reactive Oxygen Species; Retina; Retinal Degeneration; Rotenone	2021
Ginsenoside Rg3 exerts a neuroprotective effect in rotenone-induced Parkinson's disease mice via its anti-oxidative properties. European journal of pharmacology, 2021, Oct-15, Volume: 909 Topics: Animals; Antioxidants; Disease Models, Animal; Ginsenosides; Humans; Male; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinson Disease, Secondary; Reactive Oxygen Species; Rotenone; Substantia Nigra	2021
Benefits of betanin in rotenone-induced Parkinson mice. Metabolic brain disease, 2021, Volume: 36, Issue:8 Topics: Animals; Betacyanins; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2021
Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models. Cells, 2021, 07-21, Volume: 10, Issue:8 Topics: Adenine; Animals; Animals, Genetically Modified; Antioxidants; Antiparkinson Agents; Astrocytes; Autophagy; Behavior, Animal; Dihydroxyphenylalanine; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Male; Motor Activity; Nerve Degeneration; NF-E2-Related Factor 2; Oleanolic Acid; Parkinsonian Disorders; Phenotype; Rats, Sprague-Dawley; Repressor Proteins; Rotenone; Signal Transduction; Sirolimus	2021
Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy. Cell chemical biology, 2017, Apr-20, Volume: 24, Issue:4 Topics: Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Behavior, Animal; Cell Line, Tumor; Disease Models, Animal; Electron Transport Complex I; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Parkinson Disease; Protein Kinases; Protein Serine-Threonine Kinases; RNA Interference; Rotenone; Sequestosome-1 Protein; Trifluoperazine; Zebrafish; Zebrafish Proteins	2017
Protective role of apigenin on rotenone induced rat model of Parkinson's disease: Suppression of neuroinflammation and oxidative stress mediated apoptosis. Chemico-biological interactions, 2017, May-01, Volume: 269 Topics: Animals; Apigenin; Apoptosis; Behavior, Animal; Calcium-Transporting ATPases; Catalase; Corpus Striatum; Disease Models, Animal; Immunohistochemistry; Inflammation; Male; Nerve Growth Factors; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase	2017
Neuroprotective effect of resveratrol on rotenone-treated C57BL/6 mice. Neuroreport, 2017, Jun-14, Volume: 28, Issue:9 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Insecticides; Iron; Male; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Neuroprotective Agents; Psychomotor Disorders; Random Allocation; Resveratrol; Rotarod Performance Test; Rotenone; Stilbenes; Substantia Nigra; Tyrosine 3-Monooxygenase	2017
Imaging short-lived reactive oxygen species (ROS) with endogenous contrast MRI. Journal of magnetic resonance imaging : JMRI, 2018, Volume: 47, Issue:1 Topics: Animals; Brain; Contrast Media; Disease Models, Animal; Egg White; Gadolinium DTPA; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Image Enhancement; Magnetic Resonance Imaging; Male; Mice; Oxygen; Phantoms, Imaging; Reactive Oxygen Species; Reproducibility of Results; Rotenone; Sensitivity and Specificity; Serum Albumin, Bovine; Temperature	2018
Thymoquinone exerts neuroprotective effect in animal model of Parkinson's disease. Toxicology letters, 2017, Jul-05, Volume: 276 Topics: Animals; Antioxidants; Basal Ganglia; Behavior, Animal; Benzoquinones; Cytoprotection; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Dynamins; Male; Motor Activity; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats, Wistar; Rotenone; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Ubiquitin-Protein Ligases	2017
Daily chronomics of proteomic profile in aging and rotenone-induced Parkinson's disease model in male Wistar rat and its modulation by melatonin. Biogerontology, 2017, Volume: 18, Issue:4 Topics: Age Factors; Aging; Animals; Biomarkers; Brain; Circadian Rhythm; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Male; Melatonin; Nerve Tissue Proteins; Parkinsonian Disorders; Pineal Gland; Proteomics; Rats, Wistar; Rotenone; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substantia Nigra; Suprachiasmatic Nucleus; Time Factors	2017
Baicalein exerts anti-neuroinflammatory effects to protect against rotenone-induced brain injury in rats. International immunopharmacology, 2017, Volume: 50 Topics: Animals; Brain Injuries; Cell Line; Cytokines; Disease Models, Animal; Flavanones; Humans; Inflammation Mediators; Male; Mice; Microglia; Motor Activity; Neurogenic Inflammation; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Scutellaria baicalensis; Toll-Like Receptor 4	2017
Assessment of gait dynamics in rotenone-induced rat model of Parkinson's disease by footprint method. Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:3(Suppl.) Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Disease Models, Animal; Dopamine; Gait; Male; Motor Activity; Muscle Weakness; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotenone	2017
Baicalein Protects against Rotenone-Induced Neurotoxicity through Induction of Autophagy. Biological & pharmaceutical bulletin, 2017, Sep-01, Volume: 40, Issue:9 Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dopamine; Flavanones; Homeostasis; Humans; Insecticides; Male; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Phytotherapy; Plant Extracts; Reactive Oxygen Species; Rotenone; Scutellaria baicalensis	2017
Time-course of striatal Toll-like receptor expression in neurotoxic, environmental and inflammatory rat models of Parkinson's disease. Journal of neuroimmunology, 2017, 09-15, Volume: 310 Topics: Animals; Corpus Striatum; Cytokines; Disease Models, Animal; Gene Expression Regulation; Oxidopamine; Parkinson Disease; Poly I-C; Rats; Rats, Sprague-Dawley; Rotenone; Time Factors; Toll-Like Receptors	2017
Therapeutic effects of baicalein on rotenone-induced Parkinson's disease through protecting mitochondrial function and biogenesis. Scientific reports, 2017, 08-30, Volume: 7, Issue:1 Topics: Animals; Disease Models, Animal; Flavanones; Mitochondria; Neuroprotective Agents; Organelle Biogenesis; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rotenone; Therapeutic Uses	2017
Effects of mild running on substantia nigra during early neurodegeneration. Journal of sports sciences, 2018, Volume: 36, Issue:12 Topics: alpha-Synuclein; Animals; Autophagy; Disease Models, Animal; Hydrogen Peroxide; Male; Mitophagy; Neurodegenerative Diseases; Physical Conditioning, Animal; Proteasome Endopeptidase Complex; Rats, Inbred Lew; Rotenone; Running; Substantia Nigra; Tyrosine 3-Monooxygenase	2018
Protective effects of resveratrol on mitochondrial function in the hippocampus improves inflammation-induced depressive-like behavior. Physiology & behavior, 2017, Dec-01, Volume: 182 Topics: Animals; Antidepressive Agents; Antioxidants; Apoptosis; Cyclic N-Oxides; Depression; Disease Models, Animal; Food Preferences; Hippocampus; Inflammation; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred ICR; Mitochondria; Resveratrol; Rotenone; Stilbenes; Swimming; Uncoupling Agents	2017
The neuroprotective effects of hydro-alcoholic extract of olive (Olea europaea L.) leaf on rotenone-induced Parkinson's disease in rat. Metabolic brain disease, 2018, Volume: 33, Issue:1 Topics: Animals; Antioxidants; Disease Models, Animal; Dopaminergic Neurons; Lipid Peroxidation; Male; Neuroprotective Agents; Olea; Oxidative Stress; Parkinson Disease, Secondary; Plant Extracts; Plant Leaves; Rats, Wistar; Reactive Oxygen Species; Rotenone	2018
Lowered iPLA Experimental neurology, 2018, Volume: 300 Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Group VI Phospholipases A2; Humans; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Mesencephalon; Mitochondria; Oxidative Stress; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Rotenone	2018
Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development. Journal of pharmaceutical and biomedical analysis, 2018, Feb-05, Volume: 149 Topics: Acetonitriles; Animals; Antiparkinson Agents; Biological Availability; Brain; Chromatography, High Pressure Liquid; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dopamine; Drosophila melanogaster; Epoxide Hydrolases; Formates; Humans; Male; Parkinson Disease, Secondary; Pyrazoles; Reproducibility of Results; Rotenone; Spectrometry, Mass, Electrospray Ionization; Sulfonamides; Tandem Mass Spectrometry	2018
The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury. Nature communications, 2017, 12-12, Volume: 8, Issue:1 Topics: Acetaminophen; Adolescent; Adult; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Overdose; Electron Transport Complex I; Female; Gene Knockout Techniques; Hepatocytes; HSP40 Heat-Shock Proteins; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Middle Aged; Mitochondria, Liver; Mitochondrial Proteins; Molecular Chaperones; Primary Cell Culture; RNA, Small Interfering; Rotenone; Uncoupling Agents; Young Adult	2017
Potential neuroprotective effect of androst-5-ene-3β, 17β-diol (ADIOL) on the striatum, and substantia nigra in Parkinson's disease rat model. Journal of cellular physiology, 2018, Volume: 233, Issue:8 Topics: alpha-Synuclein; Androstenediol; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Estrogen Receptor beta; Inflammation Mediators; Male; Motor Activity; Neurons; Neuroprotective Agents; NF-kappa B; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2018
Impaired Wnt signaling in dopamine containing neurons is associated with pathogenesis in a rotenone triggered Drosophila Parkinson's disease model. Scientific reports, 2018, 02-05, Volume: 8, Issue:1 Topics: Animals; Cell Survival; Disease Models, Animal; Dopaminergic Neurons; Drosophila; Gene Expression Profiling; Parkinson Disease; Pesticides; Rotenone; Wnt Signaling Pathway	2018
Improved neuroprotective effect of resveratrol nanoparticles as evinced by abrogation of rotenone-induced behavioral deficits and oxidative and mitochondrial dysfunctions in rat model of Parkinson's disease. Naunyn-Schmiedeberg's archives of pharmacology, 2018, Volume: 391, Issue:4 Topics: Animals; Antioxidants; Behavior, Animal; Brain; Disease Models, Animal; Male; Mitochondria; Nanoparticles; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats, Wistar; Resveratrol; Rotenone; Stilbenes	2018
Cilostazol Mediated Nurr1 and Autophagy Enhancement: Neuroprotective Activity in Rat Rotenone PD Model. Molecular neurobiology, 2018, Volume: 55, Issue:9 Topics: Animals; Apoptosis; Autophagy; Behavior, Animal; Biomarkers; Cilostazol; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Inflammation Mediators; Male; Motor Activity; Neostriatum; Neuroprotective Agents; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinson Disease; Rats, Wistar; Rotarod Performance Test; Rotenone; Sirtuin 1; Tyrosine 3-Monooxygenase	2018
Tephrosin attenuates sepsis induced acute lung injury in rats by impeding expression of ICAM-1 and MIP-2. Microbial pathogenesis, 2018, Volume: 117 Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cecum; Chemokine CXCL2; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Intercellular Adhesion Molecule-1; Lung; Lung Injury; Lymphocyte Count; Male; Neutrophils; Protective Agents; Rats; Rats, Sprague-Dawley; Rotenone; Sepsis	2018
Rotenone induces gastrointestinal pathology and microbiota alterations in a rat model of Parkinson's disease. Neurotoxicology, 2018, Volume: 65 Topics: Animals; Colon; Diarrhea; Disease Models, Animal; Gastric Emptying; Gastrointestinal Diseases; Male; Microbiota; Parkinson Disease, Secondary; Rats; Rotarod Performance Test; Rotenone	2018
Anacardic Acids from Cashew Nuts Prevent Behavioral Changes and Oxidative Stress Induced by Rotenone in a Rat Model of Parkinson's Disease. Neurotoxicity research, 2018, Volume: 34, Issue:2 Topics: Anacardic Acids; Animals; Antioxidants; Brain; Disease Models, Animal; Electron Transport Chain Complex Proteins; Exploratory Behavior; Insecticides; Lipid Peroxidation; Locomotion; Male; Maze Learning; Mental Disorders; Oxidative Stress; Parkinson Disease; Rats; Rats, Wistar; Rotarod Performance Test; Rotenone; Superoxide Dismutase	2018
Early signs of colonic inflammation, intestinal dysfunction, and olfactory impairments in the rotenone-induced mouse model of Parkinson's disease. Behavioural pharmacology, 2018, Volume: 29, Issue:2 and 3-Sp Topics: Animals; Brain; Colon; Disease Models, Animal; Gastrointestinal Tract; Inflammation; Mice; Neurons; Olfactory Bulb; Parkinson Disease; Peroxidase; Rotenone	2018
Zinc and linoleic acid pre-treatment attenuates biochemical and histological changes in the midbrain of rats with rotenone-induced Parkinsonism. BMC neuroscience, 2018, 05-09, Volume: 19, Issue:1 Topics: Animals; Antioxidants; Disease Models, Animal; Female; Glutathione; Levodopa; Linoleic Acid; Lipid Peroxidation; Parkinsonian Disorders; Rats, Wistar; Rotenone; Zinc	2018
Preliminary optimization of a Chinese herbal medicine formula based on the neuroprotective effects in a rat model of rotenone-induced Parkinson's disease. Journal of integrative medicine, 2018, Volume: 16, Issue:4 Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Male; Neuroprotective Agents; Parkinson Disease; Plants, Medicinal; Rats; Rats, Wistar; Rotenone	2018
Neuroprotective effect of agmatine (decarboxylated l-arginine) against oxidative stress and neuroinflammation in rotenone model of Parkinson's disease. Human & experimental toxicology, 2019, Volume: 38, Issue:2 Topics: Agmatine; Animals; Cytokines; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutathione; Male; Malondialdehyde; Mesencephalon; Neuroprotective Agents; Oxidative Stress; Parkinson Disease, Secondary; Rats, Sprague-Dawley; Rotenone; Tyrosine 3-Monooxygenase	2019
Nicotine-Induced Neuroprotection in Rotenone In Vivo and In Vitro Models of Parkinson's Disease: Evidences for the Involvement of the Labile Iron Pool Level as the Underlying Mechanism. Neurotoxicity research, 2019, Volume: 35, Issue:1 Topics: Analysis of Variance; Animals; Cell Count; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Embryo, Mammalian; Exploratory Behavior; Fluoresceins; Forelimb; Insecticides; Iron; Male; Medial Forebrain Bundle; Mesencephalon; Motor Activity; Nicotine; Nicotinic Agonists; Parkinson Disease; Pars Compacta; Rats; Rats, Sprague-Dawley; Rotenone; Tubulin; Tyrosine 3-Monooxygenase	2019
Melatonin Improves Behavioral and Biochemical Outcomes in a Rotenone-Induced Rat Model of Parkinson's Disease. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2018, Volume: 37, Issue:2 Topics: Animals; Disease Models, Animal; Male; Melatonin; Muscle Strength; Neurotoxins; Neurotransmitter Agents; Parkinson Disease; Postural Balance; Psychomotor Disorders; Rats; Rats, Wistar; Rotenone; Tyrosine 3-Monooxygenase	2018
Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism. Experimental neurology, 2018, Volume: 309 Topics: Adenosine Triphosphate; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Green Fluorescent Proteins; Membrane Potential, Mitochondrial; Membrane Proteins; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Movement; Mutation; Paraquat; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone	2018
Olfaction in female Wistar rats is influenced by dopaminergic periglomerular neurons after nigral and bulbar lesions. Behavioural pharmacology, 2019, Volume: 30, Issue:4 Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Female; Olfactory Bulb; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Signal Transduction; Sleep Deprivation; Sleep, REM; Smell; Substantia Nigra	2019
Signature of Aberrantly Expressed microRNAs in the Striatum of Rotenone-Induced Parkinsonian Rats. Neurochemical research, 2018, Volume: 43, Issue:11 Topics: Animals; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Male; MicroRNAs; Neostriatum; Neuroprotective Agents; Parkinson Disease; Parkinsonian Disorders; Rats, Wistar; Rotenone; Substantia Nigra	2018
Caffeic acid improves locomotor activity and lessens inflammatory burden in a mouse model of rotenone-induced nigral neurodegeneration: Relevance to Parkinson's disease therapy. Pharmacological reports : PR, 2019, Volume: 71, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Antiparkinson Agents; Apoptosis; Behavior, Animal; Caffeic Acids; CD11b Antigen; Cyclooxygenase 2; Disease Models, Animal; Dopamine; Inflammation Mediators; Locomotion; Male; Mice; Motor Activity; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; Parkinsonian Disorders; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2019
Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model. Brain, behavior, and immunity, 2019, Volume: 76 Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopaminergic Neurons; Histamine; Indoles; Inflammation; Male; Microglia; Nerve Degeneration; Parkinson Disease; Parkinsonian Disorders; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H4; Rotenone	2019
Demethoxycurcumin ameliorates rotenone-induced toxicity in rats. Frontiers in bioscience (Elite edition), 2019, 01-01, Volume: 11, Issue:1 Topics: Animals; Apoptosis; Behavior, Animal; Cognitive Dysfunction; Curcumin; Diarylheptanoids; Disease Models, Animal; Male; Neuroprotective Agents; Parkinson Disease; Random Allocation; Rats, Wistar; Rotenone	2019
Antiapoptotic role of Agaricus blazei extract in rodent model of Parkinson's disease. Frontiers in bioscience (Elite edition), 2019, 01-01, Volume: 11, Issue:1 Topics: Agaricus; Animals; Complex Mixtures; Disease Models, Animal; Male; Mice; Neuroprotective Agents; Parkinson Disease; Rotenone	2019
Curcumin restores rotenone induced depressive-like symptoms in animal model of neurotoxicity: assessment by social interaction test and sucrose preference test. Metabolic brain disease, 2019, Volume: 34, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Choice Behavior; Corpus Striatum; Curcumin; Depression; Disease Models, Animal; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Neuronal Plasticity; Neuroprotective Agents; Rats; Rats, Wistar; Rotenone; Serotonin; Social Behavior	2019
Selective inhibition of mitochondrial sodium-calcium exchanger protects striatal neurons from α-synuclein plus rotenone induced toxicity. Cell death & disease, 2019, 01-28, Volume: 10, Issue:2 Topics: alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Humans; Mitochondria; Neurons; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Sodium-Calcium Exchanger	2019
Chronic sleep restriction in the rotenone Parkinson's disease model in rats reveals peripheral early-phase biomarkers. Scientific reports, 2019, 02-13, Volume: 9, Issue:1 Topics: Amino Acids, Branched-Chain; Animals; Area Under Curve; Biomarkers; Chromatography, High Pressure Liquid; Chronic Disease; Discriminant Analysis; Disease Models, Animal; Least-Squares Analysis; Male; Mass Spectrometry; Metabolome; Parkinson Disease; Rats; Rats, Wistar; ROC Curve; Rotenone; Sleep Wake Disorders	2019
MG132 protects against renal dysfunction by regulating Akt-mediated inflammation in diabetic nephropathy. Scientific reports, 2019, 02-14, Volume: 9, Issue:1 Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Glomerular Mesangium; Glucose; Humans; Inflammation; Inflammation Mediators; Kidney; Leupeptins; Male; Mesangial Cells; Proteasome Inhibitors; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Rotenone; Signal Transduction	2019
Hydroxychloroquine antiparkinsonian potential: Nurr1 modulation versus autophagy inhibition. Behavioural brain research, 2019, 06-03, Volume: 365 Topics: Animals; Antiparkinson Agents; Apoptosis; Autophagy; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Hydroxychloroquine; Male; Microtubule-Associated Proteins; Motor Activity; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Tyrosine 3-Monooxygenase	2019
Complex I syndrome in striatum and frontal cortex in a rat model of Parkinson disease. Free radical biology & medicine, 2019, 05-01, Volume: 135 Topics: Animals; Brain; Corpus Striatum; Disease Models, Animal; Electron Transport Complex I; Frontal Lobe; Gray Matter; Humans; Hydrogen Peroxide; Hypokinesia; Lipid Peroxidation; Locomotion; Mitochondria; Oxidative Stress; Oxygen; Parkinson Disease; Rats; Rotenone	2019
Standarized Tribulus terrestris extract protects against rotenone-induced oxidative damage and nigral dopamine neuronal loss in mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2018, Volume: 69, Issue:6 Topics: Animals; Antioxidants; Disease Models, Animal; DNA Damage; Dopamine; Mice; Microglia; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Plant Extracts; Rotenone; Substantia Nigra; Tribulus; Up-Regulation	2018
Sex Differences in Rotenone Sensitivity Reflect the Male-to-Female Ratio in Human Parkinson's Disease Incidence. Toxicological sciences : an official journal of the Society of Toxicology, 2019, 07-01, Volume: 170, Issue:1 Topics: alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Female; Humans; Lysosomes; Male; Microglia; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone; Sex Factors; Substantia Nigra; Transferrin; Tyrosine 3-Monooxygenase	2019
Neuroprotective role of kolaviron in striatal redo-inflammation associated with rotenone model of Parkinson's disease. Neurotoxicology, 2019, Volume: 73 Topics: alpha-Synuclein; Animals; Anti-Inflammatory Agents; Antiparkinson Agents; Apoptosis; Behavior, Animal; Corpus Striatum; Cytokines; Disease Models, Animal; Exploratory Behavior; Flavonoids; Inflammation Mediators; Locomotion; Male; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats, Wistar; Reactive Oxygen Species; Rotenone; Tyrosine 3-Monooxygenase	2019
Neuroprotective Effects of Thymol, a Dietary Monoterpene Against Dopaminergic Neurodegeneration in Rotenone-Induced Rat Model of Parkinson's Disease. International journal of molecular sciences, 2019, Mar-27, Volume: 20, Issue:7 Topics: Animals; Catalase; Cyclooxygenase 2; Cytokines; Diet; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Inflammation Mediators; Lipid Peroxidation; Male; Malondialdehyde; Neostriatum; Nerve Degeneration; Neuroglia; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease; Rats, Wistar; Rotenone; Substantia Nigra; Superoxide Dismutase; Thymol; Tyrosine 3-Monooxygenase	2019
Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity. The Journal of nutritional biochemistry, 2019, Volume: 69 Topics: Acetylation; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Butyrates; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Glial Cell Line-Derived Neurotrophic Factor; Histones; Male; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Neuroglia; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Probiotics; Rotenone	2019
Synergistic anticataleptic effect of imipramine and nicotine in a rotenone-induced rat model. Psychopharmacology, 2019, Volume: 236, Issue:11 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Catalepsy; Disease Models, Animal; Dose-Response Relationship, Drug; Imipramine; Insecticides; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2019
Inhibition of the mitochondrial complex-1 protects against carbon tetrachloride-induced acute liver injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 115 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Electron Transport Complex I; Male; Mice, Inbred C57BL; Mitochondria, Liver; Oxidative Stress; Rotenone	2019
Lycopodium Attenuates Loss of Dopaminergic Neurons by Suppressing Oxidative Stress and Neuroinflammation in a Rat Model of Parkinson's Disease. Molecules (Basel, Switzerland), 2019, Jun-10, Volume: 24, Issue:11 Topics: alpha-Synuclein; Animals; Antioxidants; Brain; Catalase; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Inflammation; Inflammation Mediators; Lipid Peroxidation; Lycopodium; Male; Malondialdehyde; Matrix Metalloproteinases; Microglia; Nerve Degeneration; Neuroprotection; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Parkinson Disease; Plant Extracts; Rats, Wistar; Rotenone; Superoxide Dismutase	2019
Sleep deprivation caused a memory defects and emotional changes in a rotenone-based zebrafish model of Parkinson's disease. Behavioural brain research, 2019, 10-17, Volume: 372 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cognition; Disease Models, Animal; Dopamine; Emotions; Male; Memory; Motor Activity; Parkinson Disease; Rotenone; Sleep Deprivation; Zebrafish	2019
Colonic electrical stimulation improves colonic transit in rotenone-induced Parkinson's disease model through affecting enteric neurons. Life sciences, 2019, Aug-15, Volume: 231 Topics: alpha-Synuclein; Animals; Choline O-Acetyltransferase; Colon; Constipation; Disease Models, Animal; Electric Stimulation; Enteric Nervous System; Gastrointestinal Motility; Intestine, Small; Male; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2019
Neuroprotective Properties of Standardized Extracts of Hypericum perforatum on Rotenone Model of Parkinson's Disease. CNS & neurological disorders drug targets, 2013, Volume: 12, Issue:5 Topics: Analysis of Variance; Animals; Apoptosis Regulatory Proteins; Brain; Catalepsy; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Fluorodeoxyglucose F18; Hypericum; Insecticides; Liposomes; Male; Maze Learning; Neurons; Neuroprotective Agents; Parkinson Disease; Phytotherapy; Positron-Emission Tomography; Quercetin; Rats; Rats, Wistar; Rotenone; Swimming	2013
Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage. Neuroscience letters, 2013, Apr-29, Volume: 541 Topics: Action Potentials; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Male; Nerve Degeneration; Neural Conduction; Peripheral Nervous System Diseases; Pesticides; Rats; Rats, Sprague-Dawley; Rotenone; Sciatic Nerve; Tail	2013
Increased SUMO-1 expression in the unilateral rotenone-lesioned mouse model of Parkinson's disease. Neuroscience letters, 2013, Jun-07, Volume: 544 Topics: Aging; alpha-Synuclein; Animals; Brain; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Parkinsonian Disorders; Rotenone; SUMO-1 Protein; Up-Regulation	2013
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta neuropathologica, 2013, Volume: 125, Issue:6 Topics: alpha-Synuclein; Animals; Brain; Cell Culture Techniques; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred C57BL; Parkinson Disease; Prion Diseases; Prions; Pyrazoles; Pyrimidines; Rotenone	2013
Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease. Neuroscience, 2013, Aug-29, Volume: 246 Topics: Animals; Animals, Genetically Modified; Butyric Acid; Disease Models, Animal; Drosophila; Histone Deacetylase Inhibitors; Motor Activity; Parkinson Disease, Secondary; Pesticides; Rotenone	2013
p38(MAPK)/p53-Mediated Bax induction contributes to neurons degeneration in rotenone-induced cellular and rat models of Parkinson's disease. Neurochemistry international, 2013, Volume: 63, Issue:3 Topics: Animals; bcl-2-Associated X Protein; Disease Models, Animal; Male; Neurons; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; PC12 Cells; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Tumor Suppressor Protein p53; Tyrosine 3-Monooxygenase	2013
PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice. ACS chemical neuroscience, 2013, Sep-18, Volume: 4, Issue:9 Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Calcium Signaling; Cell Line; Cerebral Infarction; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Evaluation, Preclinical; Hippocampus; Memory Disorders; Mice; Molecular Structure; Molecular Targeted Therapy; Naphthyridines; Nerve Tissue Proteins; Neuroprotective Agents; Oligomycins; Oxidative Stress; Phosphorylation; Protein Phosphatase 2; Protein Processing, Post-Translational; Rats; Rotenone; Scopolamine; tau Proteins	2013
bFGF promotes the differentiation and effectiveness of human bone marrow mesenchymal stem cells in a rotenone model for Parkinson's disease. Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:2 Topics: Animals; Behavior, Animal; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Female; Fibroblast Growth Factor 2; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Motor Activity; Neurogenesis; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Time Factors	2013
Inhibition of endoplasmic reticulum stress is involved in the neuroprotective effects of candesartan cilexitil in the rotenone rat model of Parkinson's disease. Neuroscience letters, 2013, Aug-26, Volume: 548 Topics: Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Disease Models, Animal; Dopaminergic Neurons; Endoplasmic Reticulum; Humans; Male; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Inbred Lew; Rotenone; Tetrazoles; Uncoupling Agents	2013
Gastrodin ameliorates Parkinson's disease by downregulating connexin 43. Molecular medicine reports, 2013, Volume: 8, Issue:2 Topics: Animals; Astrocytes; Benzyl Alcohols; Cell Communication; Connexin 43; Disease Models, Animal; Down-Regulation; Gap Junctions; Gene Expression Regulation; Glucosides; Parkinson Disease; Phosphorylation; Rats; Rotenone	2013
Mitochondrial oxidative stress corrupts coronary collateral growth by activating adenosine monophosphate activated kinase-α signaling. Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:8 Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Cells, Cultured; Coronary Vessels; Disease Models, Animal; Endothelial Cells; Humans; Ischemia; Mitochondria; Myocardium; Oxidative Stress; Rats; Rats, Inbred WKY; Rotenone; Signal Transduction; TOR Serine-Threonine Kinases; Uncoupling Agents	2013
Probenecid potentiates MPTP/MPP+ toxicity by interference with cellular energy metabolism. Journal of neurochemistry, 2013, Volume: 127, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopaminergic Neurons; Drug Synergism; Electron Transport Complex I; Energy Metabolism; Mice; Neurotoxins; Parkinson Disease; Probenecid; Rotenone; Uricosuric Agents	2013
Complex I inhibition in the visual pathway induces disorganization of the node of Ranvier. Neurobiology of disease, 2013, Volume: 58 Topics: Animals; Cell Adhesion Molecules; Cell Adhesion Molecules, Neuronal; Cell Count; Contactins; Demyelinating Diseases; Disease Models, Animal; Electron Transport Complex I; Insecticides; Male; Myelin Proteins; Nerve Tissue Proteins; Optic Nerve; Ranvier's Nodes; Rats; Rats, Long-Evans; Reactive Oxygen Species; Rotenone; Time Factors; Visual Pathways	2013
REM sleep deprivation generates cognitive and neurochemical disruptions in the intranigral rotenone model of Parkinson's disease. Journal of neuroscience research, 2013, Volume: 91, Issue:11 Topics: Animals; Behavior, Animal; Cognition; Corpus Striatum; Disease Models, Animal; Injections, Intraventricular; Learning; Male; Memory; Parkinsonian Disorders; Rats; Rats, Wistar; Rotenone; Sleep Deprivation; Uncoupling Agents	2013
Implications of enzyme deficiencies on mitochondrial energy metabolism and reactive oxygen species formation of neurons involved in rotenone-induced Parkinson's disease: a model-based analysis. The FEBS journal, 2013, Volume: 280, Issue:20 Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Electron Transport Complex I; Energy Metabolism; Ketoglutarate Dehydrogenase Complex; Mitochondria; Neurons; Parkinson Disease; Rats; Reactive Oxygen Species; Rotenone	2013
Ameliorative effect of Sida cordifolia in rotenone induced oxidative stress model of Parkinson's disease. Neurotoxicology, 2013, Volume: 39 Topics: Animals; Brain; Catalepsy; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Insecticides; Male; Malvaceae; Neurotransmitter Agents; Oxidative Stress; Parkinson Disease; Phytotherapy; Plant Extracts; Postural Balance; Rats; Rats, Sprague-Dawley; Rotenone; Sensation Disorders; Thiobarbituric Acid Reactive Substances	2013
Sesamol and naringenin reverse the effect of rotenone-induced PD rat model. Neuroscience, 2013, Dec-19, Volume: 254 Topics: Animals; Benzodioxoles; Disease Models, Animal; Flavanones; Male; Parkinson Disease, Secondary; Phenols; Rats; Rats, Wistar; Rotenone	2013
[Effect of lycopene on oxidative stress and behavioral deficits in rotenone induced model of Parkinson's disease]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2013, Volume: 29, Issue:4 Topics: Animals; Behavior, Animal; Brain; Carotenoids; Disease Models, Animal; Dopamine; Lycopene; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neurons; Oxidative Stress; Parkinson Disease; Rotenone; Superoxide Dismutase	2013
Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson's disease. Neurobiology of aging, 2014, Volume: 35, Issue:5 Topics: Animals; Caspase 3; Disease Models, Animal; Dopaminergic Neurons; Inflammation; Lythraceae; Male; Mitochondrial Diseases; Nitric Oxide Synthase Type II; Oxidative Stress; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Tyrosine	2014
Parkinson's disease, lights and melanocytes: looking beyond the retina. Scientific reports, 2014, Jan-29, Volume: 4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Female; Light; Male; Melanocytes; Motor Activity; Oxidopamine; Paraquat; Parkinson Disease; Rats; Rats, Sprague-Dawley; Retina; Rotenone	2014
Do adipose tissue-derived mesenchymal stem cells ameliorate Parkinson's disease in rat model? Human & experimental toxicology, 2014, Volume: 33, Issue:12 Topics: Adipose Tissue; Amino Acids; Animals; Antigens, CD; Brain; Brain-Derived Neurotrophic Factor; Carbidopa; Cell Differentiation; Cells, Cultured; Chemokine CCL2; Disease Models, Animal; Drug Combinations; Female; Gene Expression; Genes, sry; Levodopa; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Ovariectomy; Parkinson Disease; Rats, Sprague-Dawley; Rotenone; Transforming Growth Factor beta; Tyrosine 3-Monooxygenase	2014
Cell therapy using retinal progenitor cells shows therapeutic effect in a chemically-induced rotenone mouse model of Leber hereditary optic neuropathy. European journal of human genetics : EJHG, 2014, Volume: 22, Issue:11 Topics: Animals; Cell- and Tissue-Based Therapy; Cells, Cultured; Dependovirus; Disease Models, Animal; Electron Transport Complex I; Genetic Markers; Magnetic Resonance Imaging; Mice; Mitochondria; Mutation; Optic Atrophy, Hereditary, Leber; Optic Nerve; Retina; Retinal Ganglion Cells; Rotenone; Saccharomyces cerevisiae Proteins; Stem Cell Transplantation; Stem Cells	2014
Neuroprotection by valproic acid in an intrastriatal rotenone model of Parkinson's disease. Neuroscience, 2014, May-16, Volume: 267 Topics: Analysis of Variance; Animals; Disease Models, Animal; Dopaminergic Neurons; Functional Laterality; Insecticides; Male; Neuroprotective Agents; Parkinson Disease; Postural Balance; Rats; Rats, Sprague-Dawley; Rotenone; Sensation Disorders; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Valproic Acid	2014
Inhibition of neuroinflammation and mitochondrial dysfunctions by carbenoxolone in the rotenone model of Parkinson's disease. Molecular neurobiology, 2015, Volume: 51, Issue:1 Topics: Animals; Antioxidants; Astrocytes; Carbenoxolone; Citrulline; Cytokines; Disease Models, Animal; Electron Transport; Enzyme Activation; Glial Fibrillary Acidic Protein; Glutathione; Inflammation; Inflammation Mediators; Male; Mesencephalon; Mitochondria; Nervous System; Nitric Oxide; Nitric Oxide Synthase Type II; Parkinson Disease; Rats, Sprague-Dawley; Rotenone	2015
Millettia pachycarpa exhibits anti-inflammatory activity through the suppression of LPS-induced NO/iNOS expression. The American journal of Chinese medicine, 2014, Volume: 42, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cells, Cultured; Depression, Chemical; Disease Models, Animal; Edema; Flavones; Flavonoids; Lipopolysaccharides; Macrophages; Male; Mice, Inbred ICR; Millettia; Nitric Oxide; Nitric Oxide Synthase Type II; Phytotherapy; Rotenone; Seeds	2014
The mitochondrial complex I inhibitor rotenone induces endoplasmic reticulum stress and activation of GSK-3β in cultured rat retinal cells. Investigative ophthalmology & visual science, 2014, Jul-31, Volume: 55, Issue:9 Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum Stress; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunohistochemistry; In Situ Nick-End Labeling; Rats; Reactive Oxygen Species; Retinal Neurons; Rotenone; Uncoupling Agents	2014
A new Drosophila model to study the interaction between genetic and environmental factors in Parkinson's disease. Brain research, 2014, Oct-02, Volume: 1583 Topics: Aging; alpha-Synuclein; Animals; Animals, Genetically Modified; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Gene-Environment Interaction; Humans; Image Processing, Computer-Assisted; Larva; Motor Activity; Mutation; Olfactory Perception; Parkinson Disease; Rotenone; Software; Video Recording	2014
Potential efficacy of dopamine loaded-PVP/PAA nanogel in experimental models of Parkinsonism: possible disease modifying activity. Journal of biomedical materials research. Part A, 2015, Volume: 103, Issue:5 Topics: Acrylic Resins; Animals; Catalepsy; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Male; Nanogels; Parkinsonian Disorders; Polyethylene Glycols; Polyethyleneimine; Povidone; Rats, Wistar; Rotenone; Spectroscopy, Fourier Transform Infrared; Treatment Outcome	2015
Methods to characterize spontaneous and startle-induced locomotion in a rotenone-induced Parkinson's disease model of Drosophila. Journal of visualized experiments : JoVE, 2014, Aug-17, Issue:90 Topics: Animals; Disease Models, Animal; Drosophila; Locomotion; Male; Parkinson Disease; Reflex, Startle; Rotenone	2014
Putative role of monoamines in the antidepressant-like mechanism induced by striatal MT2 blockade. Behavioural brain research, 2014, Dec-15, Volume: 275 Topics: Animals; Biogenic Monoamines; Corpus Striatum; Depression; Disease Models, Animal; Insecticides; Male; Rats; Rats, Wistar; Receptors, Melatonin; Rotenone; Sleep Deprivation; Statistics as Topic; Swimming; Tetrahydronaphthalenes	2014
Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism. Experimental neurology, 2015, Volume: 263 Topics: Aldehyde Dehydrogenase; Animals; Benzamides; Benzodioxoles; Cell Line; Disease Models, Animal; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Microscopy, Confocal; MPTP Poisoning; Neurons; Parkinsonian Disorders; Rats; Reactive Oxygen Species; Rotenone; Uncoupling Agents	2015
A viral peptide that targets mitochondria protects against neuronal degeneration in models of Parkinson's disease. Nature communications, 2014, Oct-21, Volume: 5 Topics: Animals; Axons; Disease Models, Animal; Female; HEK293 Cells; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Microfluidics; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria; Neurodegenerative Diseases; Neurons; Parkinson Disease; Peptides; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rotenone; Viral Nonstructural Proteins	2014
Daily rhythms of serotonin metabolism and the expression of clock genes in suprachiasmatic nucleus of rotenone-induced Parkinson's disease male Wistar rat model and effect of melatonin administration. Biogerontology, 2015, Volume: 16, Issue:1 Topics: Animals; ARNTL Transcription Factors; Circadian Rhythm; CLOCK Proteins; Cryptochromes; Disease Models, Animal; Gene Expression; Male; Melatonin; Parkinson Disease, Secondary; Period Circadian Proteins; Rats; Rats, Wistar; Rotenone; Serotonin; Suprachiasmatic Nucleus; Time Factors	2015
Saxagliptin: a novel antiparkinsonian approach. Neuropharmacology, 2015, Volume: 89 Topics: Adamantane; Animals; Antiparkinson Agents; Body Weight; Brain; Cathepsin C; Cyclic AMP; Dipeptides; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Gene Expression Regulation; Insecticides; Lipid Peroxidation; Male; Nerve Tissue Proteins; NF-E2-Related Factor 2; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Tyrosine 3-Monooxygenase	2015
The rotenone-induced rat model of Parkinson's disease: behavioral and electrophysiological findings. Behavioural brain research, 2015, Feb-15, Volume: 279 Topics: Animals; Beta Rhythm; Disease Models, Animal; Male; Motor Activity; Motor Cortex; Neostriatum; Neurons; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Rotenone; Substantia Nigra; Subthalamic Nucleus; Tyrosine 3-Monooxygenase	2015
Long-term evaluation of Leber's hereditary optic neuropathy-like symptoms in rotenone administered rats. Neuroscience letters, 2015, Jan-12, Volume: 585 Topics: Animals; Disease Models, Animal; Electroretinography; Evoked Potentials, Visual; Humans; Microspheres; Optic Atrophy, Hereditary, Leber; Rats; Rotenone; Superior Colliculi; Tomography, Optical Coherence	2015
Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson's Disease: Modulation of Mitochondrial Perturbations. Molecular neurobiology, 2016, Volume: 53, Issue:2 Topics: Adenosine Triphosphate; Animals; Apoptosis; Behavior, Animal; Caspases; Disease Models, Animal; Dopamine; Gene Expression Regulation; Male; Mitochondria; Neostriatum; Neurons; Parkinson Disease; Rats, Wistar; RNA, Messenger; Rotenone; Ursodeoxycholic Acid	2016
Targeting metabolic plasticity in breast cancer cells via mitochondrial complex I modulation. Breast cancer research and treatment, 2015, Volume: 150, Issue:1 Topics: Adaptation, Physiological; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Electron Transport Complex I; Female; Heterografts; Humans; Metabolic Networks and Pathways; Mice; Mitochondria; Oxidation-Reduction; Proteome; Proteomics; Rotenone; Signal Transduction; Tumor Burden; Uncoupling Agents	2015
Combined oral supplementation of fish oil and quercetin enhances neuroprotection in a chronic rotenone rat model: relevance to Parkinson's disease. Neurochemical research, 2015, Volume: 40, Issue:5 Topics: Administration, Oral; Animals; Disease Models, Animal; Drug Therapy, Combination; Fish Oils; Hand Strength; Male; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Quercetin; Rats; Rats, Wistar; Rotenone	2015
N-acetylcysteine prevents rotenone-induced Parkinson's disease in rat: An investigation into the interaction of parkin and Drp1 proteins. Brain research bulletin, 2015, Volume: 113 Topics: Acetylcysteine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Drug Interactions; Dynamins; Male; Oxidative Stress; Parkinsonian Disorders; Protein Binding; Random Allocation; Rats; Rats, Wistar; Rotarod Performance Test; Rotenone; Substantia Nigra; Ubiquitin-Protein Ligases	2015
LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. Free radical research, 2015, Volume: 49, Issue:5 Topics: Animals; Arachidonic Acid; Biomarkers; Cardiolipins; Chromatography, High Pressure Liquid; Disease Models, Animal; Docosahexaenoic Acids; Linoleic Acid; Male; Mass Spectrometry; Mitochondria; Oxidation-Reduction; Parkinsonian Disorders; Rats, Inbred Lew; Rotenone; Substantia Nigra; Time Factors	2015
[Modification of experimental rotenone model of Parkinson's disease]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2015, Volume: 61, Issue:1 Topics: Animals; Behavior, Animal; Cell Count; Disease Models, Animal; Dopaminergic Neurons; Injections, Intraventricular; Male; Maze Learning; Microscopy, Electron; Mitochondria; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotenone; Stereotaxic Techniques; Substantia Nigra; Tyrosine 3-Monooxygenase; Uncoupling Agents	2015
shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model. The Journal of clinical investigation, 2015, Jul-01, Volume: 125, Issue:7 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Gene Knockdown Techniques; Male; Nerve Degeneration; Parkinsonian Disorders; Rats; Rats, Inbred Lew; Rats, Transgenic; RNA, Messenger; RNA, Small Interfering; Rotenone; Substantia Nigra	2015
Aging-related rotenone-induced neurochemical and behavioral deficits: role of SIRT2 and redox imbalance, and neuroprotection by AK-7. Drug design, development and therapy, 2015, Volume: 9 Topics: Aging; Animals; Benzamides; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Male; Neuroprotective Agents; Oxidation-Reduction; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Sirtuin 2; Substantia Nigra; Sulfonamides	2015
PPARβ/δ Agonist Provides Neuroprotection by Suppression of IRE1α-Caspase-12-Mediated Endoplasmic Reticulum Stress Pathway in the Rotenone Rat Model of Parkinson's Disease. Molecular neurobiology, 2016, Volume: 53, Issue:6 Topics: Animals; Apoptosis; Caspase 12; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Endoplasmic Reticulum Stress; Endoribonucleases; Fluorescent Antibody Technique; Male; Motor Activity; Multienzyme Complexes; Neostriatum; Neuroprotection; Parkinson Disease; PPAR delta; PPAR-beta; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; Rotenone; Signal Transduction; Thiazoles	2016
Autophagy-related protein expression in the substantia nigra and eldepryl intervention in rat models of Parkinson's disease. Brain research, 2015, Nov-02, Volume: 1625 Topics: Animals; Apoptosis Regulatory Proteins; Beclin-1; Disease Models, Animal; Insecticides; Male; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Selegiline; Substantia Nigra; Time Factors	2015
Differential pattern of motor impairments in neurotoxic, environmental and inflammation-driven rat models of Parkinson's disease. Behavioural brain research, 2016, Jan-01, Volume: 296 Topics: Animals; Disease Models, Animal; Lipopolysaccharides; Neostriatum; Neurotoxins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone	2016
Blockade of metabotropic glutamate receptor 5 protects against DNA damage in a rotenone-induced Parkinson's disease model. Free radical biology & medicine, 2015, Volume: 89 Topics: Animals; Blotting, Western; Cell Line; Comet Assay; Disease Models, Animal; DNA Damage; DNA Repair; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Immunohistochemistry; Male; Membrane Potential, Mitochondrial; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Rotenone; Uncoupling Agents	2015
Neuroprotective potential of ferulic acid in the rotenone model of Parkinson's disease. Drug design, development and therapy, 2015, Volume: 9 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Brain; Calcium-Binding Proteins; Coumaric Acids; Cyclooxygenase 2; Cytokines; Cytoprotection; Disease Models, Animal; Dopaminergic Neurons; Glial Fibrillary Acidic Protein; Glutathione; Inflammation Mediators; Lipid Peroxidation; Male; Microfilament Proteins; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress; Parkinsonian Disorders; Rats, Wistar; Reactive Oxygen Species; Rotenone; Time Factors	2015
Tianma Gouteng Yin, a Traditional Chinese Medicine decoction, exerts neuroprotective effects in animal and cellular models of Parkinson's disease. Scientific reports, 2015, Nov-18, Volume: 5 Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Apoptosis; Cell Count; Cell Line, Tumor; Chromatography, Liquid; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Drosophila; Drug Antagonism; Drugs, Chinese Herbal; Humans; Male; Mass Spectrometry; Medicine, Chinese Traditional; Neuroprotective Agents; Parkinson Disease; Rats; Rotenone	2015
Amelioration of apoptotic events in the skeletal muscle of intra-nigrally rotenone-infused Parkinsonian rats by Morinda citrifolia--up-regulation of Bcl-2 and blockage of cytochrome c release. Food & function, 2016, Volume: 7, Issue:2 Topics: Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Creatine Kinase; Cytochromes c; Disease Models, Animal; L-Lactate Dehydrogenase; Male; Mitochondria; Morinda; Muscle, Skeletal; Oxidative Stress; Parkinsonian Disorders; Pars Compacta; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Rotenone; Up-Regulation	2016
Evidence of neuroprotective effects of saffron and crocin in a Drosophila model of parkinsonism. Neurotoxicology, 2016, Volume: 52 Topics: Acetylcholinesterase; Animals; Antioxidants; Biomarkers; Carotenoids; Crocus; Disease Models, Animal; Dopamine; Drosophila melanogaster; Glutathione; Hydrogen Peroxide; Locomotion; Longevity; Mitochondria; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Paraquat; Parkinsonian Disorders; Phytotherapy; Plant Extracts; Protein Carbonylation; Reactive Oxygen Species; Rotenone; Sulfhydryl Compounds	2016
Chronic low-dose melatonin treatment maintains nigrostriatal integrity in an intrastriatal rotenone model of Parkinson's disease. Brain research, 2016, Feb-15, Volume: 1633 Topics: Animals; Antioxidants; Corpus Striatum; Disease Models, Animal; Immunohistochemistry; Male; Melatonin; Parkinsonian Disorders; Random Allocation; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Uncoupling Agents	2016
Inhibition of endoplasmic reticulum stress-activated IRE1α-TRAF2-caspase-12 apoptotic pathway is involved in the neuroprotective effects of telmisartan in the rotenone rat model of Parkinson's disease. European journal of pharmacology, 2016, Apr-05, Volume: 776 Topics: Animals; Apoptosis; Benzimidazoles; Benzoates; Caspase 12; Catalepsy; Disease Models, Animal; Dopamine; Endoplasmic Reticulum Stress; Endoribonucleases; Enzyme Activation; Male; Multienzyme Complexes; Neostriatum; Neuroprotective Agents; Parkinson Disease; Pars Compacta; PPAR delta; PPAR-beta; Protein Serine-Threonine Kinases; Rats; Rotenone; Signal Transduction; Telmisartan; TNF Receptor-Associated Factor 2	2016
Modulatory effects of resveratrol on endoplasmic reticulum stress-associated apoptosis and oxido-inflammatory markers in a rat model of rotenone-induced Parkinson's disease. Chemico-biological interactions, 2016, May-05, Volume: 251 Topics: Animals; Apoptosis; Biomarkers; Caspase 3; Chemically-Induced Disorders; Disease Models, Animal; Endoplasmic Reticulum Stress; Enzyme Activation; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Inflammation; Male; Membrane Proteins; Parkinson Disease; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; Rotenone; Stilbenes; Transcription Factor CHOP	2016
Upregulation of the cannabinoid CB2 receptor in environmental and viral inflammation-driven rat models of Parkinson's disease. Experimental neurology, 2016, Volume: 283, Issue:Pt A Topics: Analysis of Variance; Animals; CD11b Antigen; Chromatography, High Pressure Liquid; Disease Models, Animal; Environment; Functional Laterality; Insecticides; Male; Motor Activity; Parkinson Disease; Poly I-C; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; RNA, Messenger; Rotenone; Tandem Mass Spectrometry; Time Factors; Up-Regulation	2016
[SYNERGISTIC ACTIVITY OF DEGUELIN AND FLUDARABINE IN PRIMARY CELLS FROM CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS (CLL) AND IN A CLL MURINE MODEL]. Anales de la Real Academia Nacional de Medicina, 2014, Volume: 131, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Apoptosis; Disease Models, Animal; Drug Synergism; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Mice; Middle Aged; Primary Cell Culture; Rotenone; Tumor Cells, Cultured; Vidarabine	2014
From the Cover: Alterations in Optineurin Expression and Localization in Pre-clinical Parkinson's Disease Models. Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 153, Issue:2 Topics: alpha-Synuclein; Animals; Autophagy; Cell Cycle Proteins; Corpus Striatum; Disease Models, Animal; Membrane Transport Proteins; Mesencephalon; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Transcription Factor TFIIIA	2016
Tetramethylpyrazine Ameliorates Rotenone-Induced Parkinson's Disease in Rats: Involvement of Its Anti-Inflammatory and Anti-Apoptotic Actions. Molecular neurobiology, 2017, Volume: 54, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain; Cyclooxygenase 2; Disease Models, Animal; Male; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Pyrazines; Rats, Sprague-Dawley; Rotenone; Vasodilator Agents	2017
Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson's Disease. Neurochemical research, 2016, Volume: 41, Issue:11 Topics: Animals; Antioxidants; Curcumin; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Drosophila melanogaster; Oxidative Stress; Rats; Rotenone; Up-Regulation	2016
Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways. Scientific reports, 2016, 08-24, Volume: 6 Topics: Animals; Autophagy; Cell Line; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Humans; Isothiocyanates; Male; Mice, Inbred BALB C; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Parkinson Disease; Rotenone; Sulfoxides; TOR Serine-Threonine Kinases	2016
Interaction between subclinical doses of the Parkinson's disease associated gene, α-synuclein, and the pesticide, rotenone, precipitates motor dysfunction and nigrostriatal neurodegeneration in rats. Behavioural brain research, 2017, 01-01, Volume: 316 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Functional Laterality; Green Fluorescent Proteins; Insecticides; Male; Motor Disorders; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Vibrissae	2017
Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease. PloS one, 2016, Volume: 11, Issue:9 Topics: alpha-Synuclein; Animals; Caspase 3; Disease Models, Animal; Glucosides; Humans; Microtubule-Associated Proteins; Molecular Dynamics Simulation; Parkinson Disease; Phenols; Protein Binding; Rats; Rats, Sprague-Dawley; Rotenone	2016
Aged Lewis rats exposed to low and moderate doses of rotenone are a good model for studying the process of protein aggregation and its effects upon central nervous system cell physiology. Arquivos de neuro-psiquiatria, 2016, Volume: 74, Issue:9 Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Central Nervous System; Disease Models, Animal; Hippocampus; Immunohistochemistry; Locus Coeruleus; Male; Oxidative Stress; Parkinson Disease; Protein Aggregation, Pathological; Protein Carbonylation; Rats, Inbred Lew; Reproducibility of Results; Rotenone; Substantia Nigra	2016
Effect of Oleracein E, a Neuroprotective Tetrahydroisoquinoline, on Rotenone-Induced Parkinson's Disease Cell and Animal Models. ACS chemical neuroscience, 2017, 01-18, Volume: 8, Issue:1 Topics: Alkaloids; Animals; Apoptosis; bcl-2-Associated X Protein; Body Weight; Brain; Cell Line, Tumor; Disease Models, Animal; Exploratory Behavior; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Insecticides; L-Lactate Dehydrogenase; Male; MAP Kinase Signaling System; Mice; Monoamine Oxidase; Neuroblastoma; Neuroprotective Agents; Parkinson Disease, Secondary; Phenols; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Rotenone; Statistics, Nonparametric; Tyrosine 3-Monooxygenase	2017
Parkinson's disease-like motor and non-motor symptoms in rotenone-treated zebrafish. Neurotoxicology, 2017, Volume: 58 Topics: Animals; Anxiety; Dark Adaptation; Disease Models, Animal; Gene Expression Regulation; Insecticides; Locomotion; Male; Neurotransmitter Agents; Olfaction Disorders; Parkinson Disease, Secondary; RNA, Messenger; Rotenone; Zebrafish; Zebrafish Proteins	2017
Morinda citrifolia mitigates rotenone-induced striatal neuronal loss in male Sprague-Dawley rats by preventing mitochondrial pathway of intrinsic apoptosis. Redox report : communications in free radical research, 2017, Volume: 22, Issue:6 Topics: Animals; Apoptosis; Disease Models, Animal; Dopaminergic Neurons; Male; Mitochondria; Morinda; Parkinson Disease; Plant Extracts; Rats; Rats, Sprague-Dawley; Rotenone; Signal Transduction	2017
Synthesis and neuroprotective effects of the complex nanoparticles of iron and sapogenin isolated from the defatted seeds of Camellia oleifera. Pharmaceutical biology, 2017, Volume: 55, Issue:1 Topics: Acetylcholine; Animals; Behavior, Animal; Biomarkers; Biphenyl Compounds; Brain; Camellia; Chlorides; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Compounding; Ferric Compounds; Free Radical Scavengers; Injections, Intravenous; Injections, Subcutaneous; Male; Malondialdehyde; Metal Nanoparticles; Mice; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Picrates; Plants, Medicinal; Rotenone; Sapogenins; Seeds; Superoxide Dismutase; Tyrosine 3-Monooxygenase	2017
Bilateral upregulation of α-synuclein expression in the mouse substantia nigra by intracranial rotenone treatment. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2017, Volume: 69, Issue:2 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Immunohistochemistry; Injections, Intraventricular; Insecticides; Male; Mice; Parkinson Disease; Rotenone; Substantia Nigra; Up-Regulation	2017
Pituitary adenylate cyclase-activating polypeptide (PACAP) has a neuroprotective function in dopamine-based neurodegeneration in rat and snail parkinsonian models. Disease models & mechanisms, 2017, 02-01, Volume: 10, Issue:2 Topics: Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Feeding Behavior; Locomotion; Mass Spectrometry; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Oxidopamine; Parkinson Disease; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Deglycase DJ-1; Proteomics; Rats, Wistar; Rotenone; Serotonin; Snails; Substantia Nigra; Survival Analysis	2017
Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson's disease. Scientific reports, 2017, 01-18, Volume: 7 Topics: Administration, Oral; Aging; Animals; Apoptosis; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Electron Transport Complex I; Gene Knock-In Techniques; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis, Site-Directed; Neurons; Parkinson Disease; Rotenone; Synaptosomes; Vacuolar Proton-Translocating ATPases	2017
Asiaticoside: Attenuation of rotenone induced oxidative burden in a rat model of hemiparkinsonism by maintaining the phosphoinositide-mediated synaptic integrity. Pharmacology, biochemistry, and behavior, 2017, Volume: 155 Topics: Animals; Behavior, Animal; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Male; Maze Learning; Oxidative Stress; Parkinsonian Disorders; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Rotarod Performance Test; Rotenone; Synapses; Triterpenes	2017
Sitagliptin and liraglutide reversed nigrostriatal degeneration of rodent brain in rotenone-induced Parkinson's disease. Inflammopharmacology, 2017, Volume: 25, Issue:3 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Disease Models, Animal; Glial Cell Line-Derived Neurotrophic Factor; Interleukin-1beta; Interleukin-6; Liraglutide; Male; Parkinson Disease; Proto-Oncogene Proteins c-bcl-2; Rats; Rodentia; Rotenone; Sitagliptin Phosphate; Transforming Growth Factor beta1; Tyrosine 3-Monooxygenase	2017
Mechanism of the neuroprotective role of coenzyme Q10 with or without L-dopa in rotenone-induced parkinsonism. Neuropharmacology, 2008, Volume: 55, Issue:8 Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Levodopa; Mitochondria; NAD; Neurons; Parkinsonian Disorders; Proto-Oncogene Proteins c-bcl-2; Psychomotor Performance; Rats; Rotenone; Spectrophotometry; Ubiquinone; Ultrasonography; Vitamins	2008
Modulation of connexin 43 in rotenone-induced model of Parkinson's disease. Neuroscience, 2009, Apr-21, Volume: 160, Issue:1 Topics: Animals; Astrocytes; Blotting, Western; Brain; Cell Communication; Cells, Cultured; Connexin 43; Disease Models, Animal; Fluorescent Antibody Technique; Gap Junctions; Parkinson Disease; Phosphorylation; Random Allocation; Rats; Rats, Inbred Lew; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotenone; Signal Transduction	2009
Vascular pathology in male Lewis rats following short-term, low-dose rotenone administration. Veterinary pathology, 2009, Volume: 46, Issue:4 Topics: Animals; Blood Vessels; Brain; Cerebrovascular Disorders; Disease Models, Animal; Lung; Male; Parkinson Disease, Secondary; Rats; Rats, Inbred Lew; Rotenone	2009
Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease. Neurochemistry international, 2009, Volume: 55, Issue:6 Topics: Animals; Antiparkinson Agents; Cerebellum; Cerebral Cortex; Cytoprotection; Disease Models, Animal; Male; Meclofenoxate; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Uncoupling Agents	2009
Methylene blue provides behavioral and metabolic neuroprotection against optic neuropathy. Neurotoxicity research, 2009, Volume: 15, Issue:3 Topics: Adaptation, Ocular; Analysis of Variance; Animals; Brain; Choice Behavior; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electron Transport Complex I; Insecticides; Male; Methylene Blue; Mitochondria; NADH Dehydrogenase; Neurons; Neuroprotective Agents; Optic Nerve Diseases; Photic Stimulation; Rats; Rats, Long-Evans; Reaction Time; Retina; Rotenone; Visual Pathways	2009
A highly reproducible rotenone model of Parkinson's disease. Neurobiology of disease, 2009, Volume: 34, Issue:2 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Hypokinesia; Injections, Intraperitoneal; Male; Muscle Rigidity; Nerve Degeneration; Neurons; Neurotoxins; Parkinsonian Disorders; Rats; Rats, Inbred Lew; Reproducibility of Results; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase; Ubiquitins; Uncoupling Agents	2009
Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease. Experimental neurology, 2009, Volume: 218, Issue:1 Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Cell Count; Disease Models, Animal; ELAV Proteins; Enteric Nervous System; Gastric Emptying; Gastrointestinal Motility; Isometric Contraction; Male; Motor Activity; Muscle, Smooth; Neurons; Parkinson Disease, Secondary; Rats; Rats, Inbred Lew; Rotenone; Stomach Diseases; Time Factors; Tyrosine 3-Monooxygenase	2009
Pigment epithelium derived factor (PEDF) is neuroprotective in two in vitro models of Parkinson's disease. Neuroscience letters, 2009, Jul-17, Volume: 458, Issue:2 Topics: Adrenergic Agents; Animals; Cell Death; Disease Models, Animal; Embryo, Mammalian; Eye Proteins; Female; Insecticides; Nerve Growth Factors; Neurites; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Pregnancy; Rats; Rats, Sprague-Dawley; Rotenone; Serpins; Tissue Culture Techniques; Tyrosine 3-Monooxygenase	2009
Deleterious versus neuroprotective effect of metabolic inhibition after traumatic spinal cord injury. Spinal cord, 2009, Volume: 47, Issue:10 Topics: Animals; Creatine Kinase; Disease Models, Animal; Electron Transport Chain Complex Proteins; Energy Metabolism; Enzyme Inhibitors; Female; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Neuroprotective Agents; Oxidative Stress; Prospective Studies; Rats; Rats, Long-Evans; Recovery of Function; Rotenone; Sodium Azide; Spinal Cord; Spinal Cord Injuries; Thiamine Pyrophosphate; Treatment Outcome; Uncoupling Agents; Vitamin B Complex	2009
Behavioral and quantitative mitochondrial proteome analyses of the effects of simvastatin: implications for models of neural degeneration. Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:7 Topics: Animals; Disease Models, Animal; Electron Transport Chain Complex Proteins; Free Radicals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mass Spectrometry; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Recovery of Function; Rotenone; Simvastatin; Substantia Nigra; Uncoupling Agents	2009
Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology. Neurobiology of disease, 2009, Volume: 36, Issue:1 Topics: alpha-Synuclein; Animals; Body Weight; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; ELAV Proteins; ELAV-Like Protein 3; Formates; Gastrointestinal Diseases; Gastrointestinal Motility; Insecticides; Male; Neurons; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone; Statistics, Nonparametric	2009
Effects of glutamate and alpha2-noradrenergic receptor antagonists on the development of neurotoxicity produced by chronic rotenone in rats. Toxicology and applied pharmacology, 2009, Oct-15, Volume: 240, Issue:2 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Basal Ganglia; Behavior, Animal; Catalepsy; Cyclopentanes; Disease Models, Animal; Dopamine; Excitatory Amino Acid Antagonists; Hypokinesia; Idazoxan; Male; Motor Activity; Muscle Rigidity; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinsonian Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Adrenergic, alpha-2; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Rotenone; Serotonin; Substantia Nigra; Time Factors	2009
Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein. Neurotoxicity research, 2010, Volume: 17, Issue:2 Topics: alpha-Synuclein; Analysis of Variance; Animals; Brain; Cell Death; Chromatography, High Pressure Liquid; Disease Models, Animal; DNA Fragmentation; Dopamine; Drug Administration Schedule; Gene Expression Regulation; Histone Deacetylases; Immunoprecipitation; Insecticides; Male; Molecular Weight; Neuroprotective Agents; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotenone; Valproic Acid	2010
Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model. Journal of neuroscience research, 2010, Feb-01, Volume: 88, Issue:2 Topics: Animals; Body Weight; Cell Count; Cell Death; Corpus Striatum; Disease Models, Animal; Dopamine; Melatonin; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Random Allocation; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Survival Analysis; Tyrosine 3-Monooxygenase	2010
Neuroprotective efficacy of Bacopa monnieri against rotenone induced oxidative stress and neurotoxicity in Drosophila melanogaster. Neurotoxicology, 2009, Volume: 30, Issue:6 Topics: Acetylcholinesterase; Analysis of Variance; Animals; Bacopa; Butyrylcholinesterase; Catalase; Disease Models, Animal; Drosophila melanogaster; Glutathione Transferase; Insecticides; Lipid Peroxides; Male; Malondialdehyde; Neurotoxicity Syndromes; Oxidative Stress; Plant Extracts; Protein Carbonylation; Rotenone; Superoxide Dismutase; Time Factors	2009
Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease. Free radical biology & medicine, 2010, Feb-01, Volume: 48, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; alpha-Synuclein; Alternative Splicing; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Dopamine Agents; Humans; Immunoblotting; Immunoenzyme Techniques; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Oxidants; Oxidopamine; Parkinson Disease; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase; Uncoupling Agents	2010
Gene therapy using lactoferrin-modified nanoparticles in a rotenone-induced chronic Parkinson model. Journal of the neurological sciences, 2010, Mar-15, Volume: 290, Issue:1-2 Topics: Animals; Chronic Disease; Disease Models, Animal; Gene Expression Regulation; Gene Transfer Techniques; Genes, Reporter; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Green Fluorescent Proteins; Lactoferrin; Male; Nanoparticles; Neurotoxins; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Treatment Outcome; Uncoupling Agents	2010
Stereotaxical infusion of rotenone: a reliable rodent model for Parkinson's disease. PloS one, 2009, Nov-18, Volume: 4, Issue:11 Topics: alpha-Synuclein; Animals; Behavior, Animal; Disease Models, Animal; Dopamine; Electron Transport Complex I; Female; Humans; Lewy Bodies; Neurons; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Serotonin	2009
Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models. Aging cell, 2010, Volume: 9, Issue:2 Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Cell Line; Cell Line, Tumor; Disease Models, Animal; Humans; Hydrogen Sulfide; Lipid Metabolism; Male; MAP Kinase Signaling System; NADPH Oxidases; Neuroprotective Agents; NF-kappa B; Oxidation-Reduction; Oxidopamine; Oxygen Consumption; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone	2010
Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice. PloS one, 2010, Jan-19, Volume: 5, Issue:1 Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Enteric Nervous System; Mice; Mice, Inbred BALB C; Parkinson Disease; Rotenone; Stomach	2010
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circulation research, 2010, Apr-16, Volume: 106, Issue:7 Topics: Aconitate Hydratase; Aging; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Cells, Cultured; Cysteine; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Genotype; Humans; Mice; Mice, Transgenic; Mitochondria, Heart; Myocytes, Cardiac; NADH Dehydrogenase; NADPH Oxidase 4; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Oxidative Stress; Phenotype; Rats; Rats, Wistar; Rotenone; Superoxides; Transfection; Uncoupling Agents; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Function, Left	2010
Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease. Neurobiology of disease, 2010, Volume: 40, Issue:1 Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Dopamine; Drosophila melanogaster; Humans; Models, Genetic; Nerve Degeneration; Parkinson Disease; Rotenone	2010
Phenothiazines interfere with dopaminergic neurodegeneration in Caenorhabditis elegans models of Parkinson's disease. Neurobiology of disease, 2010, Volume: 40, Issue:1 Topics: Animals; Animals, Genetically Modified; Antipsychotic Agents; Caenorhabditis elegans; Disease Models, Animal; Dopamine; Humans; Insecticides; Models, Genetic; Nerve Degeneration; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Phenothiazines; Rotenone	2010
α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment. Journal of molecular neuroscience : MN, 2010, Volume: 42, Issue:2 Topics: alpha-Synuclein; Animals; Disease Models, Animal; Humans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Oncogene Proteins; Parkinsonian Disorders; Peroxiredoxins; Protein Deglycase DJ-1; Protein Kinases; Rotenone; Ubiquitin-Protein Ligases; Uncoupling Agents; Up-Regulation	2010
Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine. Progress in neuro-psychopharmacology & biological psychiatry, 2010, Aug-16, Volume: 34, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Behavior, Animal; Depression; Disease Models, Animal; Dopamine; Hippocampus; Lipopolysaccharides; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Random Allocation; Rats; Rats, Wistar; Rotenone; Serotonin	2010
Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle. Brain research, 2010, Nov-11, Volume: 1360 Topics: alpha-Synuclein; Animals; Apoptosis; Astrocytes; Calcium-Binding Proteins; Caspase 3; Cell Count; Densitometry; Disease Models, Animal; Dopamine; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Medial Forebrain Bundle; Microfilament Proteins; Microglia; Neurons; Oxidative Stress; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Superoxide Dismutase; Synapses; Synaptophysin; Tyrosine 3-Monooxygenase; Uncoupling Agents	2010
Dopamine D₁ and D₂ receptor subtypes functional regulation in corpus striatum of unilateral rotenone lesioned Parkinson's rat model: effect of serotonin, dopamine and norepinephrine. Neurological research, 2010, Volume: 32, Issue:9 Topics: Animals; Benzamides; Benzazepines; Catecholamines; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Interactions; Functional Laterality; Male; Norepinephrine; Parkinsonian Disorders; Protein Binding; Radionuclide Imaging; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotarod Performance Test; Rotenone; Serotonin; Tritium	2010
Oral administration of rotenone using a gavage and image analysis of alpha-synuclein inclusions in the enteric nervous system. Journal of visualized experiments : JoVE, 2010, Oct-26, Issue:44 Topics: Administration, Oral; alpha-Synuclein; Animals; Disease Models, Animal; Enteric Nervous System; Image Processing, Computer-Assisted; Intubation, Gastrointestinal; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Parkinsonian Disorders; Rotenone	2010
Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease. Cell death & disease, 2010, Volume: 1 Topics: 1-Methyl-4-phenylpyridinium; 14-3-3 Proteins; alpha-Synuclein; Animals; Caenorhabditis elegans; Cell Line, Tumor; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Parkinson Disease; Protein Isoforms; Proteins; RNA Interference; RNA, Small Interfering; Rotenone	2010
Characterisation of a novel model of Parkinson's disease by intra-striatal infusion of the pesticide rotenone. Neuroscience, 2011, May-05, Volume: 181 Topics: Animals; Corpus Striatum; Disease Models, Animal; Male; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Uncoupling Agents	2011
Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. The Journal of cell biology, 2011, Mar-07, Volume: 192, Issue:5 Topics: 1-Methyl-4-phenylpyridinium; Animals; Cytoplasm; Disease Models, Animal; Dopamine; Electron Transport Complex I; Mice; Microtubules; NAD; Nerve Degeneration; Parkinson Disease; Reactive Oxygen Species; Rotenone; Substantia Nigra; Vesicular Monoamine Transport Proteins	2011
Protective effect of lycopene on oxidative stress and cognitive decline in rotenone induced model of Parkinson's disease. Neurochemical research, 2011, Volume: 36, Issue:8 Topics: Acetylcholinesterase; Animals; Antioxidants; Carotenoids; Cognition; Cytochromes c; Disease Models, Animal; Humans; Lycopene; Male; NADH Dehydrogenase; Neuropsychological Tests; Oxidative Stress; Parkinson Disease, Secondary; Random Allocation; Rats; Rats, Wistar; Rotenone; Uncoupling Agents	2011
Dl-3-n-butylphthalide, a natural antioxidant, protects dopamine neurons in rotenone models for Parkinson's disease. Neurobiology of aging, 2012, Volume: 33, Issue:8 Topics: Animals; Antioxidants; Antiparkinson Agents; Benzofurans; Cell Line; Cell Survival; Disease Models, Animal; Dopaminergic Neurons; Humans; Neuroprotective Agents; Parkinsonian Disorders; Rats; Rotenone; Treatment Outcome	2012
Effects of pioglitazone and retinoic acid in a rotenone model of Parkinson's disease. Brain research bulletin, 2011, Jul-15, Volume: 85, Issue:6 Topics: Animals; Antineoplastic Agents; Antioxidants; Disease Models, Animal; Hypoglycemic Agents; Male; Motor Activity; Neuroprotective Agents; Parkinson Disease, Secondary; Pioglitazone; Rats; Rats, Wistar; Rotenone; Thiazolidinediones; Tretinoin	2011
An effective novel delivery strategy of rasagiline for Parkinson's disease. International journal of pharmaceutics, 2011, Oct-31, Volume: 419, Issue:1-2 Topics: Animals; Antiparkinson Agents; Brain; Delayed-Action Preparations; Disease Models, Animal; Fluorodeoxyglucose F18; Indans; Injections, Intraperitoneal; Lactic Acid; Male; Microspheres; Multimodal Imaging; Parkinsonian Disorders; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Positron-Emission Tomography; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Tomography, X-Ray Computed	2011
Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity. Neuroscience research, 2011, Volume: 71, Issue:4 Topics: Animals; Antiparkinson Agents; Apoptosis; Disease Models, Animal; Levodopa; Mitochondria; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rotenone; Thioctic Acid; Uncoupling Agents	2011
Myocardial uptake of 7'-(Z)-[(123)I]iodorotenone during vasodilator stress in dogs with critical coronary stenoses. Circulation. Cardiovascular imaging, 2011, Volume: 4, Issue:6 Topics: Adenosine A2 Receptor Agonists; Animals; Coronary Circulation; Coronary Stenosis; Critical Illness; Disease Models, Animal; Dogs; Echocardiography, Stress; Hemodynamics; Image Enhancement; Iodine Radioisotopes; Male; Random Allocation; Rotenone; Sensitivity and Specificity; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon	2011
Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: a new approach for an old neurotoxin. Neurotoxicity research, 2012, Volume: 21, Issue:3 Topics: Animals; Avoidance Learning; Disease Models, Animal; Dopaminergic Neurons; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Microinjections; Motor Activity; Nerve Degeneration; Parkinsonian Disorders; Rats; Rats, Wistar; Rotenone; Serotonergic Neurons; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase; Uncoupling Agents	2012
Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. Journal of pharmacological sciences, 2011, Volume: 117, Issue:3 Topics: Animals; Behavior, Animal; Benzamides; Benzodioxoles; CD11b Antigen; Cell Line, Tumor; Disease Models, Animal; Dopaminergic Neurons; Gene Knockdown Techniques; Glial Fibrillary Acidic Protein; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neuroprotective Agents; Neurotoxins; Oncogene Proteins; Oxidation-Reduction; Oxidative Stress; Oxidopamine; Parkinson Disease; Protein Deglycase DJ-1; Rats; Rats, Wistar; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2011
Mitochondria-derived superoxide and voltage-gated sodium channels in baroreceptor neurons from chronic heart-failure rats. Journal of neurophysiology, 2012, Volume: 107, Issue:2 Topics: Action Potentials; Animals; Antimycin A; Biophysics; Bridged Bicyclo Compounds, Heterocyclic; Chronic Disease; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Gene Expression Regulation; Heart Failure; Hemodynamics; Humans; Lectins; Male; Mitochondria; Multienzyme Complexes; NADH Dehydrogenase; NAV1.7 Voltage-Gated Sodium Channel; Nodose Ganglion; Patch-Clamp Techniques; Phenanthridines; Pressoreceptors; Rats; Rats, Sprague-Dawley; Rotenone; Sodium Channel Blockers; Sodium Channels; Spectrophotometry; Succinate Dehydrogenase; Superoxide Dismutase; Tetrodotoxin; Transfection	2012
Development and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenone. Neuroscience, 2012, Feb-17, Volume: 203 Topics: alpha-Synuclein; Animals; Behavior, Animal; Dependovirus; Disease Models, Animal; Male; Neurons; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2012
Circadian dysfunction in a rotenone-induced parkinsonian rodent model. Chronobiology international, 2012, Volume: 29, Issue:2 Topics: Animals; Behavior, Animal; Biological Clocks; Body Temperature; Circadian Rhythm; Disease Models, Animal; Humans; Insecticides; Motor Activity; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone	2012
Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system. Neurotoxicology, 2012, Volume: 33, Issue:3 Topics: Animals; Astrocytes; Basal Ganglia; Blood-Brain Barrier; C-Reactive Protein; Carrageenan; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Encephalitis; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Male; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Rotenone; Striatonigral Degeneration; Substantia Nigra; Time Factors; Tumor Necrosis Factor-alpha	2012
Administration of rotenone enhanced voluntary alcohol drinking behavior in C57BL/6J mice. Legal medicine (Tokyo, Japan), 2012, Volume: 14, Issue:5 Topics: Alcohol Drinking; Animals; Biogenic Monoamines; Brain Chemistry; Disease Models, Animal; Dopamine; Insecticides; Male; Mice; Mice, Inbred C57BL; Rotenone	2012
Regenerative effects of umbilical cord matrix cells (UCMCs) in a rodent model of rotenone neurotoxicity. Environmental toxicology and pharmacology, 2012, Volume: 34, Issue:2 Topics: Animals; Behavior, Animal; Catalepsy; Cell Transplantation; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Neurons; Neurotoxicity Syndromes; Parkinson Disease; Pesticides; Rotenone; Substantia Nigra; Tremor; Tyrosine 3-Monooxygenase; Umbilical Cord	2012
Selective protection of nigral dopaminergic neurons by echinacoside in a rat model of Parkinson disease induced by rotenone. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2012, Volume: 10, Issue:7 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Glycosides; Male; Neuroprotective Agents; Parkinson Disease; Random Allocation; Rats; Rats, Sprague-Dawley; Rotenone	2012
Controlled release of rasagiline mesylate promotes neuroprotection in a rotenone-induced advanced model of Parkinson's disease. International journal of pharmaceutics, 2012, Nov-15, Volume: 438, Issue:1-2 Topics: Animals; Apoptosis; Behavior, Animal; Cell Line, Tumor; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Humans; Indans; Lactic Acid; Male; Microspheres; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Parkinson Disease; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Rotenone	2012
Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy. PloS one, 2012, Volume: 7, Issue:9 Topics: Administration, Oral; Animals; Antioxidants; Cell Line; Cell Survival; Disease Models, Animal; Drug Administration Schedule; Electron Transport Complex I; Humans; Intravitreal Injections; Male; Mice; Mitochondria; Mutation; Optic Atrophy, Hereditary, Leber; Retinal Ganglion Cells; Rotenone; Ubiquinone; Visual Acuity	2012
Rotenone-induced neurotoxicity in rat brain areas: a study on neuronal and neuronal supportive cells. Neuroscience, 2013, Jan-29, Volume: 230 Topics: Analysis of Variance; Animals; Brain; Calcium-Binding Proteins; Caspase 3; CD11b Antigen; CD11c Antigen; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Insecticides; Male; Microfilament Proteins; Neuroglia; Neurons; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rotenone; Tyrosine 3-Monooxygenase	2013
Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment. Experimental neurology, 2013, Volume: 240 Topics: alpha-Synuclein; Animals; Chromosomes, Artificial, Bacterial; Disease Models, Animal; Female; Humans; Male; Mitochondria; Parkinsonian Disorders; Pregnancy; Rats; Rats, Transgenic; Rotenone	2013
Colchicine protects dopaminergic neurons in a rat model of Parkinson's disease. CNS & neurological disorders drug targets, 2012, Nov-01, Volume: 11, Issue:7 Topics: Animals; Antiparkinson Agents; Behavior, Animal; Catalepsy; Colchicine; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Dyskinesias; Injections, Intraperitoneal; Locomotion; Nerve Tissue Proteins; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Tremor; Tubulin Modulators; Tyrosine 3-Monooxygenase	2012
The behavioural and neuropathological impact of intranigral AAV-α-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats. Behavioural brain research, 2013, Apr-15, Volume: 243 Topics: alpha-Synuclein; Animals; Behavior, Animal; Disease Models, Animal; Gene-Environment Interaction; Genetic Vectors; Infusion Pumps, Implantable; Insecticides; Male; Neuropsychological Tests; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Weight Loss	2013
Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats. Neuroscience, 2013, Apr-16, Volume: 236 Topics: Animals; Antioxidants; Apoptosis; Disease Models, Animal; Electron Transport Complex I; Immunohistochemistry; In Situ Nick-End Labeling; Neuroprotective Agents; Parkinsonian Disorders; Quercetin; Rats; Rats, Sprague-Dawley; Rotenone; Uncoupling Agents; Up-Regulation	2013
Role of L-thyroxin in counteracting rotenone induced neurotoxicity in rats. Environmental toxicology and pharmacology, 2013, Volume: 35, Issue:2 Topics: Animals; Catalepsy; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Microglia; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Thyroxine; Tremor; Tyrosine 3-Monooxygenase	2013
Oxygen metabolites and hypoxic renal injury: effect of mitochondrial electron transport blockade. Renal failure, 2002, Volume: 24, Issue:3 Topics: Amitrole; Animals; Catalase; Cell Membrane; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport; Enzyme Inhibitors; Epithelial Cells; Hypoxia; Kidney Diseases; Loop of Henle; Mitochondria; Oxygen; Rats; Rotenone; Uncoupling Agents	2002
Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation. Experimental neurology, 2003, Volume: 179, Issue:1 Topics: alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Infusion Pumps, Implantable; Injections, Subcutaneous; Insecticides; Male; Nerve Tissue Proteins; Neural Pathways; Neurodegenerative Diseases; Neurons; Parkinsonian Disorders; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Synucleins; Time; Tyrosine 3-Monooxygenase	2003
Rotenone neurotoxicity: a new window on environmental causes of Parkinson's disease and related brain amyloidoses. Experimental neurology, 2003, Volume: 179, Issue:1 Topics: Amyloidosis; Animals; Brain; Disease Models, Animal; Environmental Exposure; Humans; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurotoxins; Parkinson Disease; Rats; Rotenone; Synucleins	2003
Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats. Journal of neurochemistry, 2003, Volume: 84, Issue:3 Topics: Animals; Behavior, Animal; Cell Count; Choline O-Acetyltransferase; Chronic Disease; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Drug Administration Schedule; Electron Transport Complex I; Enzyme Inhibitors; Inclusion Bodies; Infusions, Intravenous; Locus Coeruleus; Male; Mesencephalon; Motor Activity; Movement Disorders; NADH, NADPH Oxidoreductases; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroglia; Neurons; Pesticides; Phosphoproteins; Rats; Rats, Inbred Lew; Rotenone; Serotonin; Substantia Nigra; Time; Tyrosine 3-Monooxygenase	2003
Selective microglial activation in the rat rotenone model of Parkinson's disease. Neuroscience letters, 2003, May-01, Volume: 341, Issue:2 Topics: Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Astrocytes; Avian Proteins; Basigin; Blood Proteins; Corpus Striatum; Disease Models, Animal; Environmental Exposure; Glial Fibrillary Acidic Protein; Immunohistochemistry; Insecticides; Male; Membrane Glycoproteins; Microglia; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase	2003
The rotenone model of Parkinson's disease. Trends in neurosciences, 2003, Volume: 26, Issue:7 Topics: Animals; Disease Models, Animal; Insecticides; Mitochondria; Parkinson Disease; Rats; Rotenone; Uncoupling Agents	2003
Mechanism of toxicity in rotenone models of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Nov-26, Volume: 23, Issue:34 Topics: Adenosine Triphosphate; Animals; Antioxidants; Cell Death; Cell Line; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electron Transport Complex I; Enzyme Inhibitors; Humans; In Vitro Techniques; Mesencephalon; Neuroblastoma; Neurons; Neuroprotective Agents; Olfactory Bulb; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Inbred Lew; Rotenone; Time	2003
Rotenone induces non-specific central nervous system and systemic toxicity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:6 Topics: Animals; Brain; Disease Models, Animal; Dopamine; Motor Activity; Neurodegenerative Diseases; Neurons; Parkinson Disease, Secondary; Rats; Rotenone	2004
Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons. Brain research, 2004, Jul-23, Volume: 1015, Issue:1-2 Topics: Animals; Antimycin A; Calcium Channel Blockers; Calcium Channels; Cell Death; Disease Models, Animal; Drug Synergism; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Malonates; Mitochondria; Motor Neurons; Neurotoxins; Rats; Rats, Wistar; Receptors, Glutamate; Rotenone; Spinal Cord	2004
The effect of rotenone on the urinary ethanol cycle in rats fed ethanol intragastrically. Experimental and molecular pathology, 2004, Volume: 77, Issue:3 Topics: Administration, Oral; Alanine Transaminase; Animals; Disease Models, Animal; Drug Antagonism; Drug Therapy, Combination; Ethanol; Liver; Liver Diseases, Alcoholic; Male; NAD; NADH Dehydrogenase; Organ Size; Periodicity; Rats; Rats, Wistar; Rotenone; Uncoupling Agents	2004
Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease. Chemical research in toxicology, 2004, Volume: 17, Issue:11 Topics: Animals; Brain Chemistry; Cells, Cultured; Chromatography, High Pressure Liquid; Corpus Striatum; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Infusion Pumps, Implantable; Injections, Subcutaneous; Insecticides; Liver; Male; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Substantia Nigra; Uncoupling Agents	2004
Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease. Physiology & behavior, 2004, Dec-15, Volume: 83, Issue:3 Topics: Adenosine Triphosphate; Adrenal Glands; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Insecticides; Male; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Testis; Testosterone; Time Factors	2004
Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats. Journal of neuroscience research, 2005, May-01, Volume: 80, Issue:3 Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Basal Ganglia; Brain; Brain Chemistry; Catalepsy; Diazoxide; Disease Models, Animal; Dopamine; Down-Regulation; Drug Administration Schedule; Male; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parkinsonian Disorders; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Propylamines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rotenone; Uncoupling Agents	2005
Sleep disturbances in the rotenone animal model of Parkinson disease. Brain research, 2005, May-03, Volume: 1042, Issue:2 Topics: Animals; Disease Models, Animal; Male; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone; Sleep Wake Disorders	2005
Increased myocardial N-myristoyltransferase activity in rotenone model of Parkinsonism. International journal of molecular medicine, 2005, Volume: 15, Issue:6 Topics: Acyl Coenzyme A; Aminophylline; Animals; Atropine; Disease Models, Animal; Drug Combinations; Humans; Male; Nitroglycerin; Papaverine; Parkinson Disease; Phenobarbital; Rats; Rats, Inbred Lew; Rotenone	2005
Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats. The international journal of neuropsychopharmacology, 2006, Volume: 9, Issue:1 Topics: Animals; Antiparkinson Agents; Basal Ganglia; Catalepsy; Decanoic Acids; Diazoxide; Disease Models, Animal; Dopamine; Hydroxy Acids; Levodopa; Male; Motor Activity; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Parkinsonian Disorders; Potassium Channel Blockers; Potassium Channels; Propylamines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rotenone; Substantia Nigra	2006
A delivery strategy for rotenone microspheres in an animal model of Parkinson's disease. Biomaterials, 2006, Volume: 27, Issue:6 Topics: Animals; Body Weight; Calorimetry, Differential Scanning; Catalepsy; Chemical Phenomena; Chemistry, Physical; Disease Models, Animal; Drug Delivery Systems; Immunohistochemistry; Microscopy, Electron, Scanning; Microspheres; Parkinson Disease; Particle Size; Rats; Rats, Sprague-Dawley; Rotenone; Tyrosine 3-Monooxygenase; X-Ray Diffraction	2006
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans. The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52 Topics: 3-Hydroxybutyric Acid; alpha-Synuclein; Amino Acid Sequence; Animals; Animals, Genetically Modified; Antioxidants; Apoptosis; Benzoates; Benzothiazoles; Bile Acids and Salts; Caenorhabditis elegans; Cholagogues and Choleretics; Copper; Disease Models, Animal; Electron Transport Complex I; Gene Deletion; Gene Expression Regulation; Gene Library; Genetic Techniques; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Ions; Iron; Mitochondria; Molecular Sequence Data; Mutagenesis; Mutation; Neurons; Oncogene Proteins; Oxygen Consumption; Paraquat; Parkinson Disease; Polyenes; Probucol; Protein Deglycase DJ-1; Pyrazoles; Pyridazines; RNA, Small Interfering; Rotenone; Sequence Homology, Amino Acid; Sodium Azide; Taurochenodeoxycholic Acid; Thiazoles; Time Factors; Transgenes; Ubiquitin-Protein Ligases	2005
Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication. The Journal of biological chemistry, 2005, Dec-23, Volume: 280, Issue:51 Topics: Animals; Brain; Disease Models, Animal; Male; Mitochondria; Parkinson Disease; Rats; Rats, Inbred Lew; Rotenone	2005
Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:12 Topics: Adenoma; Administration, Oral; Animals; Benzo(a)pyrene; Disease Models, Animal; Lung Neoplasms; Mice; Mice, Inbred A; Rotenone; Silybin; Silybum marianum; Silymarin	2005
Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiology of disease, 2006, Volume: 22, Issue:2 Topics: alpha-Synuclein; Animals; Cell Line, Tumor; Disease Models, Animal; Electron Transport Complex I; Energy Metabolism; Humans; Insecticides; Male; Mitochondria; Nerve Degeneration; Neurons; Oncogene Proteins; Oxidative Stress; Parkinsonian Disorders; Peroxiredoxins; Proteasome Endopeptidase Complex; Protein Deglycase DJ-1; Rats; Rats, Inbred Lew; Rotenone; Signal Transduction; Substantia Nigra; Ubiquitin	2006
Methylene blue prevents neurodegeneration caused by rotenone in the retina. Neurotoxicity research, 2006, Volume: 9, Issue:1 Topics: Analysis of Variance; Animals; Brain; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport Complex IV; Enzyme Inhibitors; In Vitro Techniques; Lipid Peroxidation; Male; Methylene Blue; Mice; Mice, Inbred CBA; Models, Biological; Neurons; Oxygen Consumption; Retinal Degeneration; Rotenone; Staining and Labeling	2006
Mitochondrial electron transport in models of neuropathic and inflammatory pain. Pain, 2006, Volume: 121, Issue:1-2 Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Antimycin A; Disease Models, Animal; Drug Interactions; Electron Transport; Enzyme Inhibitors; Hyperalgesia; Male; Mitochondria; Multienzyme Complexes; Neuralgia; Neurogenic Inflammation; Pain Measurement; Pain Threshold; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Rotenone; Streptozocin; Time Factors; Uncoupling Agents; Vincristine; Zalcitabine	2006
L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats. Neurochemistry international, 2006, Volume: 49, Issue:1 Topics: Amphetamine; Animals; Catalase; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electron Transport Complex I; Hydroxyl Radical; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Selegiline; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase; Uncoupling Agents; Up-Regulation	2006
In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease. The Journal of biological chemistry, 2006, May-19, Volume: 281, Issue:20 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dependovirus; Disease Models, Animal; Electron Transport Complex I; Glial Fibrillary Acidic Protein; Mice; NADH Dehydrogenase; Parkinson Disease; Rotenone; Saccharomyces cerevisiae Proteins; Substantia Nigra; Tyrosine 3-Monooxygenase; Uncoupling Agents	2006
Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline. Journal of neurochemistry, 2006, Volume: 97, Issue:4 Topics: Animals; Anti-Bacterial Agents; Apoptosis; Cells, Cultured; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genetic Predisposition to Disease; Immunity, Innate; Male; Mice; Mice, Knockout; Mice, Transgenic; Microglia; Minocycline; NADPH Oxidases; Neurons; Neuroprotective Agents; Parkinson Disease; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase; Ubiquitin-Protein Ligases; Uncoupling Agents	2006
Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na+/K+ ATPase. Neurobiology of disease, 2006, Volume: 23, Issue:1 Topics: Animals; Cell Hypoxia; Disease Models, Animal; Dopamine; Energy Metabolism; Enzyme Inhibitors; Glucose; Membrane Potentials; Mice; Mice, Knockout; Neurons; Oncogene Proteins; Organ Culture Techniques; Ouabain; Parkinson Disease; Patch-Clamp Techniques; Peroxiredoxins; Protein Deglycase DJ-1; Rotenone; Sodium-Potassium-Exchanging ATPase; Substantia Nigra; Uncoupling Agents	2006
Iptakalim alleviates rotenone-induced degeneration of dopaminergic neurons through inhibiting microglia-mediated neuroinflammation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:12 Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Freezing Reaction, Cataleptic; Male; Membrane Potential, Mitochondrial; Microglia; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Propylamines; Rats; Rats, Sprague-Dawley; Rotenone; Tumor Necrosis Factor-alpha	2007
Behavioural and neural deficits induced by rotenone in the pond snail Lymnaea stagnalis. A possible model for Parkinson's disease in an invertebrate. The European journal of neuroscience, 2007, Volume: 25, Issue:7 Topics: Animals; Behavior, Animal; Central Nervous System; Disease Models, Animal; Dopamine; Electrophysiology; Humans; Insecticides; Lymnaea; Neurons; Parkinson Disease; Rotenone; Synaptic Transmission; Tyrosine 3-Monooxygenase	2007
Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone. Journal of neurochemistry, 2007, Volume: 101, Issue:6 Topics: alpha-Synuclein; Animals; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dopamine; Endoplasmic Reticulum; Humans; Male; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Neurons; Oxidative Stress; Parkinsonian Disorders; Phenylbutyrates; Rotenone; Substantia Nigra; Tauopathies	2007
'Rejuvenation' protects neurons in mouse models of Parkinson's disease. Nature, 2007, Jun-28, Volume: 447, Issue:7148 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Antiparkinson Agents; Calcium; Calcium Channels, L-Type; Dendrites; Disease Models, Animal; Disease Progression; Dopamine; Electric Conductivity; Gene Deletion; Male; Mice; Mice, Inbred C57BL; Mitochondria; Models, Neurological; Neurons; Parkinson Disease; Rotenone; Substantia Nigra	2007
Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats. Experimental neurology, 2007, Volume: 208, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Inhalation; Administration, Intranasal; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Herbicides; Insecticides; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neurons; Paraquat; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2007
Deguelin inhibits retinal neovascularization by down-regulation of HIF-1alpha in oxygen-induced retinopathy. Journal of cellular and molecular medicine, 2008, Volume: 12, Issue:6A Topics: Animals; Cells, Cultured; Disease Models, Animal; Down-Regulation; Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Infant, Newborn; Mice; Mice, Inbred C57BL; Oxygen; Retinal Neovascularization; Retinal Vessels; Retinopathy of Prematurity; Rotenone	2008
Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats. Journal of pineal research, 2008, Volume: 44, Issue:2 Topics: Animals; Cell Count; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Melatonin; Parkinsonian Disorders; Rats; Rats, Wistar; Receptors, Dopamine D2; Rotenone; Up-Regulation	2008
Behavioral alterations in rotenone model of Parkinson's disease: attenuation by co-treatment of centrophenoxine. Brain research, 2008, Mar-27, Volume: 1201 Topics: Animals; Antioxidants; Behavior, Animal; Brain; Catalepsy; Disease Models, Animal; Dopamine; Drug Administration Schedule; Drug Interactions; Lipid Peroxidation; Male; Meclofenoxate; Motor Activity; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Treatment Outcome; Uncoupling Agents	2008
Lysosomal changes in an animal model of myocardial ischemia. Treatment with methylprednisolone. Advances in myocardiology, 1980, Volume: 2 Topics: Acetylglucosaminidase; Animals; Coronary Disease; Cytochrome Reductases; Disease Models, Animal; Dogs; Lysosomes; Methylprednisolone; Microsomes; Microspheres; NADH Dehydrogenase; Rotenone	1980
Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons. The EMBO journal, 1999, Feb-15, Volume: 18, Issue:4 Topics: Animals; ATP-Binding Cassette Transporters; Brain; Disease Models, Animal; Dopamine; Gene Expression; Mice; Mice, Neurologic Mutants; Neurons; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotenone; Substantia Nigra; Sulfonylurea Receptors; Tolbutamide	1999
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. Journal of neuroscience research, 1999, Jul-15, Volume: 57, Issue:2 Topics: Animals; Antimetabolites; Apoptosis; Behavior, Animal; Carrier Proteins; Corpus Striatum; Deoxyglucose; Disease Models, Animal; Dopamine; Dopamine Agents; Endoplasmic Reticulum Chaperone BiP; Energy Intake; Ferrous Compounds; Heat-Shock Proteins; Heat-Shock Response; HSP70 Heat-Shock Proteins; Male; Mice; Mice, Inbred C57BL; Mitochondria; Molecular Chaperones; MPTP Poisoning; Nerve Degeneration; Neurons; Parkinson Disease, Secondary; Reactive Oxygen Species; Rotenone; Substantia Nigra; Uncoupling Agents	1999
Pesticide study aids Parkinson research. JAMA, 1999, Dec-15, Volume: 282, Issue:23 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Humans; Insecticides; Parkinson Disease; Rats; Rotenone	1999
Neuroscience. Pesticide causes Parkinson's in rats. Science (New York, N.Y.), 2000, Nov-10, Volume: 290, Issue:5494 Topics: 1-Methyl-4-phenylpyridinium; Animals; Brain; Disease Models, Animal; Dopamine; Electron Transport Complex I; Free Radicals; Humans; Insecticides; Lewy Bodies; Mitochondria; NADH, NADPH Oxidoreductases; Neurons; Parkinson Disease; Parkinsonian Disorders; Rats; Risk Factors; Rotenone; Uncoupling Agents	2000
Increased mitochondrial superoxide generation in neurons from trisomy 16 mice: a model of Down's syndrome. Free radical biology & medicine, 2000, Jan-15, Volume: 28, Issue:2 Topics: Animals; Antimycin A; Cell Death; Cells, Cultured; Chromosome Mapping; Cyanides; Diploidy; Disease Models, Animal; Down Syndrome; Electron Transport Complex I; Electron Transport Complex III; Electron Transport Complex IV; Embryonic and Fetal Development; Hippocampus; Humans; Mice; Mice, Mutant Strains; Mitochondria; NADH, NADPH Oxidoreductases; Neurons; Reactive Oxygen Species; Rotenone; Superoxides; Trisomy	2000
Mouse model of optic neuropathy caused by mitochondrial complex I dysfunction. Neuroscience letters, 2002, Jun-28, Volume: 326, Issue:2 Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Male; Mice; Mice, Inbred CBA; Mitochondria; Mitochondrial Diseases; Optic Nerve Diseases; Pharmaceutical Vehicles; Quinone Reductases; Retinal Ganglion Cells; Rotenone; Time Factors; Uncoupling Agents	2002