Page last updated: 2024-08-17

rotenone and Carcinoma, Non-Small Cell Lung

rotenone has been researched along with Carcinoma, Non-Small Cell Lung in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (26.67)29.6817
2010's9 (60.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Cui, D; Lu, G; Yao, Y; Zhang, X; Zhou, J1
Gao, F; Li, M; Li, W; Liu, H; Liu, W; Yu, X; Zhou, L1
Dong, X; Gao, F; Li, W; Ma, X; Wang, R; Wang, W1
Chen, Y; Cui, D; Han, W; Liu, X; Zhao, D1
Li, W; Liu, H; Liu, L; Ma, X; Wang, J; Xia, Z; Xie, L; Yang, Y; Yu, X; Zhou, H; Zhou, X1
Li, W; Liu, H; Liu, L; Ma, X; Wang, J; Xia, Z; Xie, L; Yang, Y; Yu, X; Zhou, H1
Bian, JJ; Chen, W; Feng, S; Hua, ZC; Shi, YL; Yin, W1
Choi, H; Hong, HS; Kim, H; Kim, HS; Kim, KC; Kim, KW; Lee, HY; Lee, J; Lee, MY; Lee, SC; Min, HY; Park, HJ; Park, SJ; Seo, JH; Seong, MA; Suh, YG1
Bao, Z; Lu, G; Yan, B; Yao, Y; Zhao, D; Zhou, J1
Chang, DJ; Geo, SY; Han, SH; Hennessy, B; Hong, WK; Kang, HJ; Kim, KW; Kim, WY; Kim, YS; Lee, HY; Mills, G; Park, HJ; Seo, SY; Suh, YG; Yoo, J1
Choi, DS; Gilbert, BE; Hong, WK; Lee, HY; Tran, HT; Woo, JK1
Fang, YC; Li, J; Wang, CY; Wang, XL1
Chung, JG; Hsia, TC; Ji, BC; Ko, YC; Lai, KC; Lai, TY; Lin, JJ; Yang, JS; Yang, ST; Yu, CC1
Hong, WK; Kosmeder, JW; Kurie, JM; Lee, HY; Pezzuto, JM; Suh, YA1
Behrens, C; Bekele, BN; Feng, L; Hong, WK; Jin, Q; Lee, HY; Wistuba, II1

Other Studies

15 other study(ies) available for rotenone and Carcinoma, Non-Small Cell Lung

ArticleYear
Deguelin Attenuates Non-Small-Cell Lung Cancer Cell Metastasis by Upregulating PTEN/KLF4/EMT Signaling Pathway.
    Disease markers, 2022, Volume: 2022

    Topics: A549 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Factor 4; Lung Neoplasms; Mice; Neoplasm Metastasis; PTEN Phosphohydrolase; Rotenone; Signal Transduction

2022
Deguelin suppresses non-small cell lung cancer by inhibiting EGFR signaling and promoting GSK3β/FBW7-mediated Mcl-1 destabilization.
    Cell death & disease, 2020, 02-21, Volume: 11, Issue:2

    Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; F-Box-WD Repeat-Containing Protein 7; Female; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Mice, Nude; Mutation; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Protein Kinase Inhibitors; Protein Stability; Rotenone; Signal Transduction; Tumor Burden; Ubiquitination; Xenograft Model Antitumor Assays

2020
Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis.
    Oncotarget, 2017, May-16, Volume: 8, Issue:20

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Down-Regulation; Glycolysis; Hexokinase; Humans; Lung Neoplasms; Mice; Rotenone

2017
Deguelin inhibits epithelial-to-mesenchymal transition and metastasis of human non-small cell lung cancer cells by regulating NIMA-related kinase 2.
    Thoracic cancer, 2017, Volume: 8, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Metastasis; NIMA-Related Kinases; Rotenone

2017
Deguelin attenuates non-small cell lung cancer cell metastasis through inhibiting the CtsZ/FAK signaling pathway.
    Cellular signalling, 2018, Volume: 50

    Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cathepsin Z; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Metastasis; Rotenone; Signal Transduction

2018
Repression of Noxa by Bmi1 contributes to deguelin-induced apoptosis in non-small cell lung cancer cells.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:12

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Mitogen-Activated Protein Kinase 7; Proto-Oncogene Proteins c-bcl-2; Rotenone; Signal Transduction

2018
Mitochondrial inhibitor sensitizes non-small-cell lung carcinoma cells to TRAIL-induced apoptosis by reactive oxygen species and Bcl-X(L)/p53-mediated amplification mechanisms.
    Cell death & disease, 2014, Dec-18, Volume: 5

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Humans; Lung Neoplasms; Mice; Mitochondria; Proto-Oncogene Proteins; Reactive Oxygen Species; Rotenone; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53

2014
Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90.
    Molecular pharmacology, 2015, Volume: 88, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzopyrans; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Mice; Mice, SCID; Quinolines; Rotenone; Signal Transduction; Xenograft Model Antitumor Assays

2015
Deguelin Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells through Regulating the Expression of Galectin-1.
    International journal of biological sciences, 2016, Volume: 12, Issue:7

    Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Female; Galectin 1; Humans; Immunoblotting; Immunoprecipitation; Lung Neoplasms; Mice; Mice, Inbred BALB C; Real-Time Polymerase Chain Reaction; Rotenone; Signal Transduction

2016
A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chemoprevention; Gene Expression; Humans; Lung Neoplasms; Rotenone; Signal Transduction

2008
Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:4

    Topics: Administration, Intranasal; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatography, High Pressure Liquid; Genes, ras; Humans; Immunohistochemistry; Liposomes; Lung Neoplasms; Mice; Mice, Mutant Strains; Precancerous Conditions; Rotenone; Tissue Distribution

2009
Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells.
    Journal of Asian natural products research, 2010, Volume: 12, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HSP90 Heat-Shock Proteins; Humans; Membrane Potential, Mitochondrial; Microscopy, Confocal; Molecular Structure; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Rotenone

2010
Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells.
    Oncology reports, 2012, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Line, Tumor; Comet Assay; DNA Damage; DNA Modification Methylases; DNA Repair Enzymes; DNA Topoisomerases, Type I; DNA-Activated Protein Kinase; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Electrophoresis, Agar Gel; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Nuclear Proteins; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; RNA, Messenger; Rotenone; Time Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2012
Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-01, Volume: 10, Issue:3

    Topics: Apoptosis; Blotting, Western; Bronchi; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclooxygenase 2; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Immunoblotting; Isoenzymes; Lung Neoplasms; Male; Membrane Proteins; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rotenone; Time Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2004
Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin.
    Cancer research, 2007, Dec-15, Volume: 67, Issue:24

    Topics: AMP-Activated Protein Kinases; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Microtubule-Associated Proteins; Multienzyme Complexes; Neoplasm Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Rotenone; Survivin; Transfection; Uncoupling Agents

2007
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