Page last updated: 2024-08-17

rotenone and Breast Neoplasms

rotenone has been researched along with Breast Neoplasms in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's3 (11.11)18.2507
2000's8 (29.63)29.6817
2010's9 (33.33)24.3611
2020's6 (22.22)2.80

Authors

AuthorsStudies
Du, L; Jekabsons, MB; Li, J; Mahdi, F; Nagle, DG; Zhou, YD1
Blackburn, BK; Carter, P; Lee, A; Mullins, S; Rodrigues, ML; Wirth, C1
Aali, E; Darzi, S; Elahian, F; Mirzaei, SA; Peymani, A; Pishkhan Dibazar, S; Rahmani, B; Shakeri Chaleshtori, L; Shirian, S1
Audet-Walsh, E; Bourmeau, G; Dufour, CR; Giguère, V; Kuasne, H; Li, X; McGuirk, S; Park, M; Scholtes, C; St-Pierre, J; Vernier, M1
Ann, J; Byun, WS; Kim, JY; Kim, YJ; Lee, J; Lee, S; Nam, G; Nguyen, CT; Park, HJ; Park, S; Sahu, R; Seo, JH1
Syahrani, RA; Wanandi, SI; Yunita, E1
Bai, HW; Bak, DH; Chung, BY; Kang, SH; Park, CH1
Ann, J; Hong Seo, J; Kim, YJ; Lee, J; Min Park, J; Nam, G; Nguyen, CT; Park, HJ; Thanh La, M; Young Kim, J1
Ann, J; Chen, J; Cho, TM; Choi, H; Chul Kim, K; Hoang, VH; Hong, M; Kim, HS; Kim, JY; Kim, KW; Lee, J; Lee, S; Nguyen, CT; Park, HJ; Seo, JH; Sub Byun, W; Suh, YG; Yong Kim, J1
Kabiraj, P; Pal, R; Roy, D1
Biener-Ramanujan, E; Ramanujan, VK; Xu, Q; Yang, W1
Li, LZ; Luo, Q; Sun, N; Xu, HN1
Li, H; Wang, X; Wu, Z; Yi, T1
Hazra, B; Kumar, A; Kumar, B; Mishra, KP; Pandey, BN1
Deng, YT; Huang, HC; Lin, JK1
Mehta, RG; Murillo, G; Peng, X; Torres, KE1
Brown, PH; Rodenberg, JM1
Chu, ZH; Huang, RF; Jiang, JW; Liang, XH; Zhan, Qz; Zhou, XL1
Boo, HJ; Kim, JH; Kim, KW; Lee, HJ; Lee, HY; Lee, SH; Min, HY; Suh, YA; Suh, YG; Sung, MA; Yun, HJ1
Koren, R; Liberman, UA; Ravid, A; Weitsman, GE1
Felty, Q; Roy, D; Singh, KP1
Karna, P; Lee, HY; Liu, X; Moriarty, RM; Naithani, R; O'Regan, RM; Peng, XH; Wood, WC; Yang, L1
Casida, JE; Fang, N1
Casida, JE; Rowlands, JC1
Chandel, NS; Schumacker, PT; Thompson, CB; Vander Heiden, MG1
Díaz-Gil, JJ; Gosálvez, M1
Graidist, P; Srisawat, T; Sritularak, B; Sukrong, S; Tedasen, A1

Other Studies

27 other study(ies) available for rotenone and Breast Neoplasms

ArticleYear
Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos.
    Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7

    Topics: Aegle; Antineoplastic Agents, Phytogenic; Breast; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Cell Survival; Coumarins; Dietary Supplements; Female; Humans; Hypoxia-Inducible Factor 1; Mitochondria; Plant Extracts

2013
Synthesis and beta-lactamase-mediated activation of a cephalosporin-taxol prodrug.
    Chemistry & biology, 1995, Volume: 2, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; beta-Lactamases; Biotransformation; Brain Chemistry; Breast Neoplasms; Cattle; Humans; Hydrolysis; Kinetics; Microtubules; Paclitaxel; Prodrugs; Recombinant Fusion Proteins; Taxoids; Tumor Cells, Cultured

1995
Improvement of cytotoxicity of mitoxantrone and daunorubicin by candidone, tephrosin, and bavachinin.
    Molecular biology reports, 2021, Volume: 48, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Cytotoxins; Daunorubicin; Female; Flavonoids; Humans; MCF-7 Cells; Mitoxantrone; Neoplasm Proteins; Rotenone; Stomach Neoplasms

2021
Estrogen-related receptors are targetable ROS sensors.
    Genes & development, 2020, 04-01, Volume: 34, Issue:7-8

    Topics: Animals; Antineoplastic Agents; Biosensing Techniques; Breast Neoplasms; Drug Resistance, Neoplasm; ERRalpha Estrogen-Related Receptor; Female; Gene Expression Regulation, Neoplastic; Glutamine; Glutathione; Humans; Mice; Oxidative Stress; Paclitaxel; Reactive Oxygen Species; Receptors, Estrogen; Rotenone; Signal Transduction; Tamoxifen

2020
Discovery of novel anti-breast cancer agents derived from deguelin as inhibitors of heat shock protein 90 (HSP90).
    Bioorganic & medicinal chemistry letters, 2020, 09-01, Volume: 30, Issue:17

    Topics: Antineoplastic Agents; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Down-Regulation; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; HSP90 Heat-Shock Proteins; Humans; Molecular Docking Simulation; Rotenone; Structure-Activity Relationship

2020
Suppression of Rotenone-Treated Human Breast Cancer Stem Cell Survival Using Survivin Inhibitor YM155 is Associated to Oxidative Stress Modulation.
    Asian Pacific journal of cancer prevention : APJCP, 2020, Sep-01, Volume: 21, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Insecticides; Naphthoquinones; Neoplastic Stem Cells; Oxidative Stress; Rotenone; Survivin; Tumor Cells, Cultured

2020
A novel radiolytic rotenone derivative, rotenoisin A, displays potent anticarcinogenic activity in breast cancer cells.
    Journal of radiation research, 2021, Mar-10, Volume: 62, Issue:2

    Topics: Antineoplastic Agents; bcl-2-Associated X Protein; Breast Neoplasms; Cell Death; Cell Proliferation; DNA Damage; Female; Humans; MAP Kinase Signaling System; MCF-7 Cells; Mitochondrial Proteins; Phosphorylation; Reactive Oxygen Species; Rotenone

2021
Discovery of a simplified deguelin analog as an HSP90 C-terminal inhibitor for HER2-positive breast cancer.
    Bioorganic & medicinal chemistry letters, 2021, 08-01, Volume: 45

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; HSP90 Heat-Shock Proteins; Humans; Molecular Docking Simulation; Molecular Structure; Rotenone; Structure-Activity Relationship

2021
Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.
    Bioorganic & medicinal chemistry, 2019, 04-01, Volume: 27, Issue:7

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; HSP90 Heat-Shock Proteins; Humans; Models, Molecular; Molecular Structure; Rotenone; Structure-Activity Relationship

2019
EF24 prevents rotenone-induced estrogenic status alteration in breast cancer.
    Cell biology international, 2014, Volume: 38, Issue:4

    Topics: Benzylidene Compounds; Breast Neoplasms; Down-Regulation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; HEK293 Cells; HeLa Cells; Humans; MCF-7 Cells; Microscopy, Confocal; Oxidative Stress; Piperidones; Protein Disulfide-Isomerases; Reactive Oxygen Species; Rotenone; Up-Regulation

2014
Targeting metabolic plasticity in breast cancer cells via mitochondrial complex I modulation.
    Breast cancer research and treatment, 2015, Volume: 150, Issue:1

    Topics: Adaptation, Physiological; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Electron Transport Complex I; Female; Heterografts; Humans; Metabolic Networks and Pathways; Mice; Mitochondria; Oxidation-Reduction; Proteome; Proteomics; Rotenone; Signal Transduction; Tumor Burden; Uncoupling Agents

2015
Potential Indexing of the Invasiveness of Breast Cancer Cells by Mitochondrial Redox Ratios.
    Advances in experimental medicine and biology, 2016, Volume: 923

    Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Movement; Energy Metabolism; Female; Flavin-Adenine Dinucleotide; Humans; MCF-7 Cells; Microscopy, Fluorescence; Mitochondria; NAD; Neoplasm Invasiveness; Oxidation-Reduction; Rotenone; Tumor Microenvironment; Uncoupling Agents

2016
Enhancement radiosensitization of breast cancer cells by deguelin.
    Cancer biotherapy & radiopharmaceuticals, 2008, Volume: 23, Issue:3

    Topics: Apoptosis; Breast Neoplasms; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Radiation-Sensitizing Agents; Rotenone; Survivin

2008
Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells.
    Molecular and cellular biochemistry, 2009, Volume: 320, Issue:1-2

    Topics: Acetylcysteine; Allopurinol; Animals; Antimycin A; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cardiolipins; Cell Line, Tumor; Cyclosporine; Cytochromes c; Female; Free Radical Scavengers; Humans; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Rotenone; Uncoupling Agents; Vitamin K 3

2009
Rotenone induces apoptosis in MCF-7 human breast cancer cell-mediated ROS through JNK and p38 signaling.
    Molecular carcinogenesis, 2010, Volume: 49, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Female; Flow Cytometry; Humans; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Rotenone; Signal Transduction

2010
Deguelin inhibits growth of breast cancer cells by modulating the expression of key members of the Wnt signaling pathway.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:11

    Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Female; Gene Expression Profiling; Humans; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotenone; Signal Transduction; Tumor Cells, Cultured; Wnt Proteins

2009
A novel look into estrogen receptor-negative breast cancer prevention with the natural, multifunctional signal transduction inhibitor deguelin.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:11

    Topics: beta Catenin; Breast Neoplasms; Female; Humans; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Rotenone; Signal Transduction; Wnt Proteins

2009
[Effects of deguelin on proliferation and apoptosis of MCF-7 breast cancer cells by phosphatidylinositol 3-kinase/Akt signaling pathway].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2011, Volume: 9, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rotenone; Signal Transduction

2011
A novel antitumor activity of deguelin targeting the insulin-like growth factor (IGF) receptor pathway via up-regulation of IGF-binding protein-3 expression in breast cancer.
    Cancer letters, 2013, May-10, Volume: 332, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Inhibitor of Apoptosis Proteins; Insulin-Like Growth Factor Binding Protein 3; MCF-7 Cells; Mice; Mice, Nude; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Receptors, Somatomedin; RNA Interference; Rotenone; Signal Transduction; Survivin; Time Factors; Transfection; Tumor Burden; Up-Regulation; Xenograft Model Antitumor Assays

2013
Vitamin D enhances caspase-dependent and -independent TNFalpha-induced breast cancer cell death: The role of reactive oxygen species and mitochondria.
    International journal of cancer, 2003, Aug-20, Volume: 106, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Calcitriol; Calcium Channel Agonists; Caspase 3; Caspase Inhibitors; Caspases; Cell Division; Cytochrome c Group; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Humans; Membrane Potentials; Mitochondria; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Rotenone; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Uncoupling Agents

2003
Estrogen-induced G1/S transition of G0-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling.
    Oncogene, 2005, Jul-21, Volume: 24, Issue:31

    Topics: Base Sequence; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Chloramphenicol; DNA Primers; Estradiol; Ethidium; G1 Phase; Humans; Mitochondria; Oligonucleotide Array Sequence Analysis; Oxidants; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; S Phase; Signal Transduction

2005
Down-regulation of inhibitor of apoptosis proteins by deguelin selectively induces apoptosis in breast cancer cells.
    Molecular pharmacology, 2007, Volume: 71, Issue:1

    Topics: Apoptosis; Breast Neoplasms; Cell Division; Cell Line, Tumor; Colony-Forming Units Assay; DNA Primers; Down-Regulation; Female; Genes, Reporter; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Survivin; X-Linked Inhibitor of Apoptosis Protein

2007
Anticancer action of cubé insecticide: correlation for rotenoid constituents between inhibition of NADH:ubiquinone oxidoreductase and induced ornithine decarboxylase activities.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-31, Volume: 95, Issue:7

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cattle; Cell Division; Electron Transport Complex I; Enzyme Activation; Female; Humans; Insecticides; Mice; NADH, NADPH Oxidoreductases; Ornithine Decarboxylase; Rats; Rotenone; Tumor Cells, Cultured; Uncoupling Agents

1998
NADH: ubiquinone oxidoreductase inhibitors block induction of ornithine decarboxylase activity in MCF-7 human breast cancer cells.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:5

    Topics: Breast Neoplasms; Electron Transport Complex I; Enzyme Induction; Epithelial Cells; Estradiol; Female; Humans; Insulin-Like Growth Factor I; NADH, NADPH Oxidoreductases; Ornithine Decarboxylase; Quinazolines; RNA, Messenger; Rotenone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uncoupling Agents

1998
Redox regulation of p53 during hypoxia.
    Oncogene, 2000, Aug-10, Volume: 19, Issue:34

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylcysteine; Animals; Antioxidants; Breast Neoplasms; Carcinoma; Cell Cycle; Cell Death; Cell Division; Cell Hypoxia; Cells, Cultured; Chick Embryo; Cobalt; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Ditiocarb; Fibroblasts; Fluoresceins; Humans; Hydrogen Peroxide; Mice; Mitochondria; Myocardium; Reactive Oxygen Species; Rotenone; Superoxide Dismutase; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Uncoupling Agents

2000
Rotenone: a possible environmental carcinogen?
    European journal of cancer, 1978, Volume: 14, Issue:12

    Topics: Animals; Breast Neoplasms; Carcinogens, Environmental; Humans; Plants, Edible; Rats; Rotenone

1978
5,7,4'-Trihydroxy-6,8-diprenylisoflavone and lupalbigenin, active components of Derris scandens, induce cell death on breast cancer cell lines.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 81

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Derris; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; Isoflavones; Mice

2016