Page last updated: 2024-08-17

rotenone and Benign Neoplasms

rotenone has been researched along with Benign Neoplasms in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's0 (0.00)18.2507
2000's5 (21.74)29.6817
2010's14 (60.87)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Datta, S; Jekabsons, MB; Li, J; Mahdi, F; Nagle, DG; Zhou, YD1
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L1
Lin, ZY; Wu, L; Yao, TZ; Yun, QZ; Zhang, TW1
Abdulmonem, WA; Alhumaydhi, FA; Chaddha, M; Elasbali, AM; Hassan, MI; Jairajpuri, DS; Mohammad, T; Sharaf, SE; Xue, B; Zhu, Z1
Bridge, G; Chelala, C; Cucchi, D; Freitas, MO; Gay, L; Martin, SA; McDonald, SAC; Rashid, S; Silver, A; Suraweera, N; Szabadkai, G; Wang, J; Williams, M; Yao, Z1
Aggarwal, D; Aggarwal, V; Bishayee, A; Kaur, G; Kumar, M; Loka, M; Masurkar, A; Mittal, S; Sak, K; Sethi, G; Tuli, HS; Varol, M1
Li, W; Ma, C; Wang, G; Xie, S; Xu, F; Xu, J; Xu, S; Yao, H; Zhu, Z1
Bhave, AS; Goh, BC; Kumar, AP; Lam, WS; Lee, SC; Lobie, PE; Marican, AABH; Sethi, G; Syn, NL; Varughese, RS; Viganeshwari, SH; Wang, J; Wang, L; Wong, AL1
Higuchi, M; Kim, A; Prior, S; Takeuchi, T; Tobita, S; Yoshihara, T1
Bilecová-Rabajdová, M; Birková, A; Durovcová, E; Gregová, K; Mareková, M; Urban, P1
Chen, M; Fan, H; Hu, Y; Lan, X; Liao, Z; Linghu, L; Yang, P; Zou, Y1
Jia, Z; Ke, Y; Li, JZ; Li, YR; Misra, HP; Trush, MA; Zhu, H1
Bhatelia, K; Chumakov, PM; Poteryakhina, A; Prajapati, P; Singh, AK; Singh, K; Singh, R; Sripada, L; Tomar, D; Zheltukhin, A1
Calderon, PB; Diepart, C; Feron, O; Gallez, B; Jordan, BF; Verrax, J1
Fogal, V; Karmali, PP; Richardson, AD; Ruoslahti, E; Scheffler, IE; Smith, JW1
Lemasters, JJ; Maldonado, EN; Mullins, MR; Patnaik, J1
Choi, Y; Lee, JH1
DAWE, CJ; SCHWARTZ, FJ; STANTON, MF1
Bottoni, P; Giardina, B; Martorana, GE; Scatena, R1
Hong, SS; Hong, WK; Jin, Q; Kim, KW; Kim, WY; Lee, HY; Myers, JN; Oh, SH; Park, HJ; Suh, YG; Woo, JK; Yazici, YD1
Hong, WK; Jeong, JW; Jin, Q; Kang, HJ; Kim, KW; Lee, HY; Oh, SH; Woo, JK1
Gosálvez Gosálvez, M1

Reviews

6 review(s) available for rotenone and Benign Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction

2015
Pharmacological basis and new insights of deguelin concerning its anticancer effects.
    Pharmacological research, 2021, Volume: 174

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Cycle; Humans; Neoplasm Metastasis; Neoplasms; Nucleophosmin; Rotenone

2021
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies.
    Pharmacological research, 2021, Volume: 166

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogenesis; Cell Proliferation; Humans; Neoplasms; Rotenone; Signal Transduction

2021
Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential.
    Cancer, 2019, 06-01, Volume: 125, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Development; Humans; Neoplasms; Rotenone

2019
Naturally occurring substances and their role in chemo-protective effects.
    Central European journal of public health, 2013, Volume: 21, Issue:4

    Topics: Biological Products; Calcitriol; Estrogen Receptor Modulators; Humans; Neoplasms; Polyphenols; Protective Agents; Retinoids; Rotenone; Sulfur Compounds; Terpenes

2013
Mitochondrial dysfunction by synthetic ligands of peroxisome proliferator activated receptors (PPARs).
    IUBMB life, 2004, Volume: 56, Issue:8

    Topics: Animals; Humans; Hypoglycemic Agents; Ligands; Lipid Metabolism; Liver; Mitochondria; Mitochondrial Diseases; Models, Biological; Neoplasms; PPAR alpha; PPAR gamma; Protein Binding; Rotenone; Thiazolidinediones

2004

Other Studies

17 other study(ies) available for rotenone and Benign Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Glycolysis inhibitor screening identifies the bis-geranylacylphloroglucinol protonophore moronone from Moronobea coccinea.
    Journal of natural products, 2012, Dec-28, Volume: 75, Issue:12

    Topics: Cell Survival; Clusiaceae; Female; Glucose; Glycolysis; Humans; Molecular Structure; Neoplasms; Phloroglucinol; Rotenone

2012
Death-Associated Protein Kinase 3 Inhibitors Identified by Virtual Screening for Drug Discovery in Cancer and Hypertension.
    Omics : a journal of integrative biology, 2022, Volume: 26, Issue:7

    Topics: Death-Associated Protein Kinases; Drug Discovery; Early Detection of Cancer; Humans; Hypertension; Ketanserin; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Protein Kinase Inhibitors; Rotenone

2022
MLH1 deficiency leads to deregulated mitochondrial metabolism.
    Cell death & disease, 2019, 10-22, Volume: 10, Issue:11

    Topics: Colorectal Neoplasms; DNA Mismatch Repair; Electron Transport Complex I; Endometrial Neoplasms; Female; HCT116 Cells; HT29 Cells; Humans; Male; Mitochondria; Mutation; MutL Protein Homolog 1; Neoplasms; Ovarian Neoplasms; Rotenone; Transfection

2019
Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; HSP90 Heat-Shock Proteins; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Proteasome Endopeptidase Complex; Rotenone; Structure-Activity Relationship

2019
Mitochondrial respiratory function induces endogenous hypoxia.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Biosensing Techniques; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Respiration; Coordination Complexes; Glucose; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Microscopy, Confocal; Mitochondria; Neoplasms; Oxygen; Rotenone

2014
Mirabijalone E: a novel rotenoid from Mirabilis himalaica inhibited A549 cell growth in vitro and in vivo.
    Journal of ethnopharmacology, 2014, Aug-08, Volume: 155, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; HeLa Cells; Hep G2 Cells; Humans; Male; Medicine, Tibetan Traditional; Mice; Mice, Neurologic Mutants; Mirabilis; Neoplasms; Plant Extracts; Plant Roots; Rotenone; S Phase Cell Cycle Checkpoints; Time Factors; Xenograft Model Antitumor Assays

2014
Mechanistic studies of cancer cell mitochondria- and NQO1-mediated redox activation of beta-lapachone, a potentially novel anticancer agent.
    Toxicology and applied pharmacology, 2014, Dec-15, Volume: 281, Issue:3

    Topics: Activation, Metabolic; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Electron Transport Complex I; Enzyme Inhibitors; Humans; Indolequinones; Mice; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Prodrugs; Reactive Oxygen Species; Reverse Transcriptase Inhibitors; Rotenone

2014
NLRX1 acts as tumor suppressor by regulating TNF-α induced apoptosis and metabolism in cancer cells.
    Biochimica et biophysica acta, 2015, Volume: 1853, Issue:5

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Carcinogenesis; Caspase 8; Cell Line, Tumor; Cell Movement; Cell Proliferation; Clone Cells; Electron Transport Chain Complex Proteins; Enzyme Activation; Humans; Mice, Nude; Mitochondria; Mitochondrial Proteins; Neoplasms; Protein Binding; Protein Transport; Reactive Oxygen Species; Rotenone; Tumor Necrosis Factor-alpha; Tumor Suppressor Proteins

2015
Comparison of methods for measuring oxygen consumption in tumor cells in vitro.
    Analytical biochemistry, 2010, Jan-15, Volume: 396, Issue:2

    Topics: Anti-Inflammatory Agents; Electrodes; Electron Spin Resonance Spectroscopy; Humans; Hydrocortisone; K562 Cells; Luminescent Measurements; Neoplasms; Oximetry; Oxygen Consumption; Rotenone; Uncoupling Agents

2010
Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation.
    Molecular and cellular biology, 2010, Volume: 30, Issue:6

    Topics: Animals; Carbon; Carrier Proteins; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Electron Transport Complex I; Gene Knockdown Techniques; Humans; Mass Spectrometry; Mice; Mitochondria; Mitochondrial Proteins; Neoplasm Metastasis; Neoplasms; Oxidative Phosphorylation; Protein Biosynthesis; Protein Stability; Rotenone

2010
Free tubulin modulates mitochondrial membrane potential in cancer cells.
    Cancer research, 2010, Dec-15, Volume: 70, Issue:24

    Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane; Colchicine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Membrane Potentials; Microtubules; Mitochondria, Liver; Neoplasms; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Rhodamines; Rotenone; Tubulin

2010
The combination of tephrosin with 2-deoxy-D-glucose enhances the cytotoxicity via accelerating ATP depletion and blunting autophagy in human cancer cells.
    Cancer biology & therapy, 2011, Dec-01, Volume: 12, Issue:11

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Deoxyglucose; Elongation Factor 2 Kinase; Enzyme Activation; Humans; Intracellular Space; Neoplasms; Rotenone

2011
HEPATIC NEOPLASMS IN NATIVE BOTTOM-FEEDING FISH OF DEEP CREEK LAKE, MARYLAND.
    Cancer research, 1964, Volume: 24

    Topics: Carcinogens; DDT; Eukaryota; Fishes; Hydrocarbons; Lakes; Liver Neoplasms; Maryland; Neoplasms; Neoplasms, Experimental; Pathology; Research; Rotenone

1964
Structural basis for depletion of heat shock protein 90 client proteins by deguelin.
    Journal of the National Cancer Institute, 2007, Jun-20, Volume: 99, Issue:12

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Binding Sites; Binding, Competitive; Cell Growth Processes; Female; Fructose-Bisphosphate Aldolase; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Mice; Mice, Nude; Models, Molecular; Neoplasms; Reactive Oxygen Species; Rotenone; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2007
Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha.
    International journal of cancer, 2008, Jan-01, Volume: 122, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Aorta; Blotting, Western; Cell Hypoxia; Cell Movement; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Culture Media, Conditioned; Cysteine Proteinase Inhibitors; Drug Combinations; Endothelium, Vascular; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Laminin; Leupeptins; Luciferases; Mice; Neoplasms; Neovascularization, Pathologic; Proteasome Endopeptidase Complex; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Tumor Cells, Cultured; Ubiquitin; Vascular Endothelial Growth Factor A; Zebrafish

2008
[Reversion of cancer and mitochondrial filamentation].
    Anales de la Real Academia Nacional de Medicina, 2000, Volume: 117, Issue:4

    Topics: Animals; Antineoplastic Agents; Doxorubicin; Drug Screening Assays, Antitumor; Mitochondria; Neoplasms; Rotenone; Thiazoles; Thiazolidines; Uncoupling Agents

2000