rotenone has been researched along with Aging in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.25) | 18.7374 |
| 1990's | 6 (12.50) | 18.2507 |
| 2000's | 14 (29.17) | 29.6817 |
| 2010's | 22 (45.83) | 24.3611 |
| 2020's | 3 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Horibe, I; Ishikawa, Y; Miyazawa, M; Nakatani, S; Sakai, N; Tsukamoto, T; Yoshioka, Y | 1 |
| Azzolin, VF; Barbisan, F; da Cruz, IBM; de Afonso Bonotto, NC; Piccoli, JDCE; Ribeiro, EAM; Teixeira, CF; Turra, BO | 1 |
| Baker, BA; Booth, FW; Childs, TE; Gladden, LB; Kavazis, AN; Mumford, PW; Osburn, SC; Parry, HA; Roberson, PA; Roberts, MD; Romero, MA; Schwartz, TS; Toedebusch, RG | 1 |
| Brunetti, G; Calabrese, EJ; Calabrese, V; Crea, R; Di Rosa, G; Saul, N; Schmitz-Linneweber, C; Scuto, M; Trovato Salinaro, A | 1 |
| Ho, DH; Nam, D; Park, SW; Seo, MK; Seol, W; Son, I | 1 |
| Jagota, A; Mattam, U | 1 |
| Costa, AJ; Erustes, AG; Pereira, GJDS; Sinigaglia-Coimbra, R; Smaili, SS; Ureshino, RP | 1 |
| Abdel-Hamid, AES; Abdel-Rahman, M; Galhom, RA; Mohammed Ali, MH; Nasr El-Din, WA | 1 |
| Hayashi, Y; Meng, J; Nakanishi, H; Ni, J; Peters, C; Qing, H; Stoka, V; Turk, V; Wu, Z | 1 |
| Bush, AI; Chrysostomou, V; Cimdins, K; Cook, MJ; Crowston, JG; Duce, JA; Hill, AF; Johannsen, VA; Lopez Sanchez, MIG; Trounce, IA; Waugh, HS | 1 |
| Gai, WP; Meedeniya, A; Pountney, DL; Rcom-H'cheo-Gauthier, A; Sharry, S; Weetman, J; Wong, MB | 1 |
| Hearon, CM; Henson, GD; LaRocca, TJ; Seals, DR | 1 |
| Lee, D; Podolsky, E; Qi, C; Varga, SJ | 1 |
| Tsukada, H | 1 |
| Gattupalli, NK; Pandey, SK; Saha, G; Singh, AK | 1 |
| Bai, J; Guan, Q; Liu, Z; Wang, M; Wang, X; Yan, Z; Yang, L; Zhang, Y | 1 |
| Croco, E; Lorenzini, A; Maier, AB; Sedivy, JM; Slagboom, PE; Waaijer, ME; Westendorp, RG | 1 |
| Andersen, PM; Birve, A; Forsgren, E; Gilthorpe, JD; Keskin, I; Lange, DJ; Marklund, SL; Synofzik, M; Weber, M | 1 |
| Ho, PW; Ho, SL; Kung, MH; Lam, CS; Leung, GC; Li, L; Liu, HF; Pang, SY; Ramsden, DB | 1 |
| Hayashi, Y; Ide, T; Kang, D; Kanki, T; Nakanishi, H; Ochi-Shindou, M; Sunagawa, K; Tsutsui, H; Wu, Z; Yamato, M; Yoshida, M | 1 |
| Chan, D; Cookson, M; Ferree, A; Ghosh, J; Goldstein, L; Guillily, MD; Hisamoto, N; Hsu, CH; Iwatsubo, T; Kuwahara, T; Lanceta, J; Matsumoto, K; Moore, L; Raghavan, K; Saha, S; Segal, L; Wolozin, B | 1 |
| Blom, J; de Koning-Treurniet, C; Dekker, P; Dirks, RW; Maier, AB; Tanke, HJ; van Heemst, D; Westendorp, RG | 1 |
| Blom, J; de Koning-Treurniet, C; Dekker, P; Dirks, RW; Maier, AB; Noppe, G; Tanke, HJ; van Heemst, D; Westendorp, RG | 1 |
| Brawek, B; Feuerstein, TJ; Huppertz, HJ; Jackisch, R; Löffler, M; Wagner, K; Wendling, AS; Weyerbrock, A | 1 |
| Kristek, F; Kucharská, J; Sumbalová, Z | 1 |
| Hsieh, CC; Papaconstantinou, J | 2 |
| Ago, T; Fu, C; Kuroda, J; Li, H; Pain, J; Sadoshima, J | 1 |
| Arnold, B; Berman, SB; Cassady, SJ; VanLaar, VS | 1 |
| Lu, GQ; Wang, XJ; Wang, Y; Yan, ZQ; Zhang, JD; Zhang, S; Zhao, YX; Zhou, HY | 1 |
| Dekker, P; Dirks, RW; Maier, AB; Slagboom, PE; Tanke, HJ; van Baalen, LM; van Heemst, D; Westendorp, RG | 1 |
| Chaves, RS; D'unhao, AM; Farizatto, KL; Ferrari, MF; Martins, SA; Melo, TQ | 1 |
| Brand, MD; Buckingham, JA; Roebuck, SJ; St-Pierre, J | 1 |
| Andringa, G; Bol, JG; Drukarch, B; Phinney, AL; van Dam, AM; van Muiswinkel, FL; Wolters, ECh | 1 |
| Chan, CS; Guzman, JN; Ilijic, E; Mercer, JN; Meredith, GE; Rick, C; Surmeier, DJ; Tkatch, T | 1 |
| Dlasková, A; Hlavatá, L; Jezek, P | 1 |
| Lemeshko, VV; Shekh, VE | 1 |
| Chang, YF; Pan, X; Rao, VV; Tsai, MJ | 1 |
| Bovina, C; Cometti, GG; Formiggini, G; Genova, ML; Ghelli, A; Lenaz, G; Marchetti, M; Merlo Pich, M; Parenti Castelli, G; Semeraro, S | 1 |
| Biagini, G; Bovina, C; Genova, ML; Gorini, A; Lenaz, G; Marchetti, M; Pallotti, F; Pugnaloni, A; Tietz, C; Villa, RF; Viticchi, C | 1 |
| Bizzozero, OA; Sanchez, P; Tetzloff, SU | 1 |
| Ishii, S; Kobayashi, T; Nagai, H; Sasaki, T; Senda, M; Soga, S | 1 |
| Botta, M; Crescenzo, R; Lionetti, L; Liverini, G; Lossa, S; Mollica, MP | 1 |
| Rasmusson, AG; Svensson, AS | 1 |
| Bovina, C; Formiggini, G; Genova, ML; Lenaz, G; Ventura, B | 1 |
| Abe, H; Furuyama, F; Hagihara, B; Kamada, T; Sato, N; Suematsu, T | 1 |
| McMillin Wood, J | 1 |
| Catani, C; Margreth, A; Salviati, G | 1 |
48 other study(ies) available for rotenone and Aging
| Article | Year |
|---|---|
Comparison of larvicidal, adulticidal and acaricidal activity of two geometrical butylidenephthalide isomers.
Topics: Aging; Angelica; Animals; Chromatography, Gas; DEET; Drosophila; Gas Chromatography-Mass Spectrometry; Insecticides; Isomerism; Larva; Mites; Phthalic Anhydrides; Rotenone; Siphonaptera | 2006 |
Rotenone-exposure as cytofunctional aging model of human dermal fibroblast prior replicative senescence.
Topics: Aging; Cells, Cultured; Cellular Senescence; Collagen; Fibroblasts; Humans; Rotenone | 2023 |
Five months of voluntary wheel running downregulates skeletal muscle LINE-1 gene expression in rats.
Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Caffeine; Chromatin; Chromosomal Proteins, Non-Histone; Cyclophilin A; DNA Methylation; Female; Gene Expression Regulation; Hydroxamic Acids; Long Interspersed Nucleotide Elements; Muscle Fibers, Skeletal; Muscle, Skeletal; Physical Conditioning, Animal; Primary Cell Culture; Rats; Rats, Wistar; Resveratrol; Ribonucleotides; RNA, Messenger; Rotenone; Sedentary Behavior | 2019 |
Healthspan Enhancement by Olive Polyphenols in
Topics: Aging; alpha-Synuclein; Animals; Animals, Genetically Modified; Biomarkers; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Diet, Mediterranean; Disease Models, Animal; Dopaminergic Neurons; Humans; Longevity; Microscopy, Fluorescence; Olea; Olive Oil; Parkinson Disease; Polyphenols; Rotenone | 2020 |
LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells.
Topics: Aging; Cellular Senescence; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lysosomes; Neurons; Oxidative Stress; Parkinson Disease; Rotenone | 2021 |
Daily chronomics of proteomic profile in aging and rotenone-induced Parkinson's disease model in male Wistar rat and its modulation by melatonin.
Topics: Age Factors; Aging; Animals; Biomarkers; Brain; Circadian Rhythm; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Male; Melatonin; Nerve Tissue Proteins; Parkinsonian Disorders; Pineal Gland; Proteomics; Rats, Wistar; Rotenone; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substantia Nigra; Suprachiasmatic Nucleus; Time Factors | 2017 |
Effects of Aging in the Striatum and Substantia Nigra of a Parkinson's Disease Animal Model.
Topics: Aging; Animals; Corpus Striatum; Parkinsonian Disorders; Rats; Rats, Wistar; Rotenone; Substantia Nigra; Uncoupling Agents | 2018 |
Therapeutic efficacy of olfactory stem cells in rotenone induced Parkinsonism in adult male albino rats.
Topics: Aging; Animals; Cells, Cultured; Male; Mesencephalon; Motor Activity; Olfactory Bulb; Parkinsonian Disorders; Rats; Rotenone; Stem Cell Transplantation; Stem Cells; Treatment Outcome; Tyrosine 3-Monooxygenase | 2018 |
Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice.
Topics: Aging; Animals; Cathepsin B; Cell Line; Cells, Cultured; Cognitive Dysfunction; Cytosol; DNA-Binding Proteins; High Mobility Group Proteins; Hippocampus; Inflammation; Memory; Mice, Inbred C57BL; Microglia; Mitochondria; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Rotenone; Subcellular Fractions | 2019 |
Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amyloid beta-Protein Precursor; Animals; Cell Line, Tumor; Child; Child, Preschool; Enzyme Activation; Female; Humans; Male; Mice; Middle Aged; Mitochondria; Neurons; Neuroprotection; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Rotenone; Toxicity Tests; Young Adult | 2019 |
Increased SUMO-1 expression in the unilateral rotenone-lesioned mouse model of Parkinson's disease.
Topics: Aging; alpha-Synuclein; Animals; Brain; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Parkinsonian Disorders; Rotenone; SUMO-1 Protein; Up-Regulation | 2013 |
Mitochondrial quality control and age-associated arterial stiffening.
Topics: Age Factors; Aging; Animals; Aorta, Thoracic; Aortic Diseases; Collagen Type I; Male; Mice, Inbred C57BL; Mitochondria; Mitophagy; Oxidation-Reduction; Oxidative Stress; Pulse Wave Analysis; Rotenone; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Superoxides; Tissue Culture Techniques; Trehalose; Vascular Stiffness | 2014 |
A new Drosophila model to study the interaction between genetic and environmental factors in Parkinson's disease.
Topics: Aging; alpha-Synuclein; Animals; Animals, Genetically Modified; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Gene-Environment Interaction; Humans; Image Processing, Computer-Assisted; Larva; Motor Activity; Mutation; Olfactory Perception; Parkinson Disease; Rotenone; Software; Video Recording | 2014 |
The use of ¹⁸F-BCPP-EF as a PET probe for complex I activity in the brain.
Topics: Aging; Amyloid beta-Peptides; Animals; Drug Design; Electron Transport Complex I; Hypoxia-Ischemia, Brain; Macaca fascicularis; Male; Molecular Probes; Positron-Emission Tomography; Pyridazines; Pyridines; Rats, Sprague-Dawley; Rotenone; Stroke | 2014 |
Pyrroloquinoline quinone (PQQ) producing Escherichia coli Nissle 1917 (EcN) alleviates age associated oxidative stress and hyperlipidemia, and improves mitochondrial function in ageing rats.
Topics: Aging; Animals; Antioxidants; Escherichia coli; Glutathione; Hyperlipidemias; Lipid Peroxidation; Male; Mitochondria; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PQQ Cofactor; Rats; Reactive Oxygen Species; Rotenone; Succinate Dehydrogenase; Superoxide Dismutase; Transcription Factors | 2015 |
Aging-related rotenone-induced neurochemical and behavioral deficits: role of SIRT2 and redox imbalance, and neuroprotection by AK-7.
Topics: Aging; Animals; Benzamides; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Male; Neuroprotective Agents; Oxidation-Reduction; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Sirtuin 2; Substantia Nigra; Sulfonamides | 2015 |
DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cells, Cultured; Cellular Senescence; DNA Damage; Female; Fibroblasts; Humans; Male; Micronuclei, Chromosome-Defective; Middle Aged; Rotenone; Telomere; Time Factors; Tissue Banks; Tumor Suppressor p53-Binding Protein 1; Young Adult | 2016 |
Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients.
Topics: Adenine; Age of Onset; Aging; Amyotrophic Lateral Sclerosis; Autophagy; Bortezomib; C9orf72 Protein; Case-Control Studies; Cells, Cultured; DNA Repeat Expansion; Electron Transport Complex I; Endoplasmic Reticulum Stress; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Genotype; Humans; Mutation; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Aggregation, Pathological; Protein Folding; Proteins; Proteolysis; Rotenone; Solubility; Superoxide Dismutase; Superoxide Dismutase-1 | 2016 |
Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson's disease.
Topics: Administration, Oral; Aging; Animals; Apoptosis; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Electron Transport Complex I; Gene Knock-In Techniques; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis, Site-Directed; Neurons; Parkinson Disease; Rotenone; Synaptosomes; Vacuolar Proton-Translocating ATPases | 2017 |
Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice.
Topics: Aging; Animals; Biological Transport; Brain; DNA Damage; DNA-Binding Proteins; DNA, Mitochondrial; HeLa Cells; Hippocampus; Humans; Intracellular Membranes; Learning; Long-Term Potentiation; Memory; Memory Disorders; Mice; Mice, Transgenic; Microglia; Mitochondrial Diseases; Mitochondrial Proteins; Motor Activity; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Recovery of Function; Rotenone; Transcription Factors; Up-Regulation | 2008 |
LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans.
Topics: Aging; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Dopamine; Gene Knockdown Techniques; Herbicides; Insecticides; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mitochondria; Mortality; Mutation; Neurons; Paraquat; Protein Serine-Threonine Kinases; RNA, Messenger; Rotenone | 2009 |
Stress-induced responses of human skin fibroblasts in vitro reflect human longevity.
Topics: Adult; Aged, 80 and over; Aging; Annexin A5; Apoptosis; beta-Galactosidase; Cellular Senescence; Female; Fibroblasts; Health Status; Humans; Longevity; Male; Oxidative Stress; Rotenone; Siblings; Skin Aging; Skin Physiological Phenomena; Smoking; Stress, Physiological | 2009 |
Rapid flow cytometric method for measuring senescence associated beta-galactosidase activity in human fibroblasts.
Topics: Adult; Age Factors; Aged, 80 and over; Aging; beta-Galactosidase; Cellular Senescence; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Lysosomes; Macrolides; Models, Biological; Rotenone; Skin | 2009 |
Reactive oxygen species (ROS) in the human neocortex: role of aging and cognition.
Topics: Adolescent; Adult; Aged; Aging; Animals; Child; Child, Preschool; Cognition; Electron Transport Complex I; Female; Humans; Infant; Male; Middle Aged; Mitochondria; Neocortex; Rats; Rats, Wistar; Reactive Oxygen Species; Reproducibility of Results; Rotenone; Young Adult | 2010 |
Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats.
Topics: Aging; alpha-Tocopherol; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Brain; Cell Respiration; Electron Transport; Electron Transport Complex IV; Glutamates; Losartan; Mitochondria; Rats; Rats, Inbred SHR; Rats, Wistar; Rotenone; Succinic Acid; Ubiquinone | 2010 |
Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS).
Topics: Acetylcysteine; Activating Transcription Factor 2; Aging; Animals; Antimycin A; Cell Proliferation; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Fibroblasts; Hydrogen Peroxide; Longevity; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Mitochondria; Nitro Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Propionates; Protein Binding; Reactive Oxygen Species; Rotenone; Skin; Thioredoxins | 2009 |
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.
Topics: Aconitate Hydratase; Aging; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Cells, Cultured; Cysteine; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Genotype; Humans; Mice; Mice, Transgenic; Mitochondria, Heart; Myocytes, Cardiac; NADH Dehydrogenase; NADPH Oxidase 4; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Oxidative Stress; Phenotype; Rats; Rats, Wistar; Rotenone; Superoxides; Transfection; Uncoupling Agents; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Function, Left | 2010 |
Integrating multiple aspects of mitochondrial dynamics in neurons: age-related differences and dynamic changes in a chronic rotenone model.
Topics: Aging; Animals; Cells, Cultured; Chronic Disease; Mitochondria; Mitochondrial Diseases; Models, Biological; Neurons; Parkinson Disease; Rats; Rotenone; Substantia Nigra; Uncoupling Agents | 2011 |
Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging, superoxide, NADPH oxidase, and p38 MAPK.
Topics: Aging; Animals; Antibodies, Blocking; Antigens, CD; Cell Culture Techniques; Cells, Cultured; Dopamine; Gene Expression; Intercellular Adhesion Molecule-1; Iron; Mesencephalon; Microglia; NADPH Oxidases; Neurons; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Rotenone; Superoxides | 2011 |
Chronic inhibition of the respiratory chain in human fibroblast cultures: differential responses related to subject chronological and biological age.
Topics: Age Factors; Aged, 80 and over; Aging; beta-Galactosidase; Biopsy; Cells, Cultured; Electron Transport; Female; Fibroblasts; Flow Cytometry; Humans; Linear Models; Male; Netherlands; Reactive Oxygen Species; Rotenone; Telomere Shortening | 2012 |
Rotenone-dependent changes of anterograde motor protein expression and mitochondrial mobility in brain areas related to neurodegenerative diseases.
Topics: Aging; Animals; Body Weight; Brain; Gene Expression Regulation; Kinesins; Mitochondria; Molecular Motor Proteins; Motor Activity; Neurodegenerative Diseases; Organ Specificity; Protein Transport; Rats; Rats, Inbred Lew; RNA, Messenger; Rotenone | 2013 |
Topology of superoxide production from different sites in the mitochondrial electron transport chain.
Topics: Aging; Animals; Antimycin A; Columbidae; Electron Transport; Enzyme Inhibitors; Female; Hydrogen Peroxide; Liver; Malates; Methacrylates; Mitochondria, Liver; Mitochondria, Muscle; Muscle, Skeletal; Myocardium; Oligomycins; Oxidants; Palmitoylcarnitine; Pyruvic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Reference Standards; Rotenone; Succinic Acid; Superoxide Dismutase; Superoxides; Thiazoles; Uncoupling Agents | 2002 |
Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice.
Topics: Aging; Animals; Catalytic Domain; Cell Line; Enzyme Activation; Gene Expression Regulation, Enzymologic; Heterozygote; Liver; Longevity; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; Mice; Mice, Inbred Strains; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Rotenone; Thioredoxins | 2006 |
Enhanced sensitivity of dopaminergic neurons to rotenone-induced toxicity with aging.
Topics: Aging; alpha-Synuclein; Animals; Astrocytes; Cell Count; Dopamine; Immunohistochemistry; Insecticides; Male; Microglia; Neostriatum; Neurons; Neurotransmitter Agents; Presynaptic Terminals; Rats; Rats, Inbred Lew; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase | 2006 |
'Rejuvenation' protects neurons in mouse models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Antiparkinson Agents; Calcium; Calcium Channels, L-Type; Dendrites; Disease Models, Animal; Disease Progression; Dopamine; Electric Conductivity; Gene Deletion; Male; Mice; Mice, Inbred C57BL; Mitochondria; Models, Neurological; Neurons; Parkinson Disease; Rotenone; Substantia Nigra | 2007 |
Oxidative stress caused by blocking of mitochondrial complex I H(+) pumping as a link in aging/disease vicious cycle.
Topics: Aging; Cell Line, Tumor; Disease; DNA, Mitochondrial; Electron Transport; Electron Transport Complex I; Fluorescent Dyes; Glucose; Humans; Intracellular Space; Membrane Potential, Mitochondrial; Microscopy, Confocal; Mitochondria; Mutation; Oxidative Stress; Phosphorylation; Rotenone; Superoxides; Uncoupling Agents | 2008 |
Hypotonic fragility of outer membrane and activation of external pathway of NADH oxidation in rat liver mitochondria are increased with age.
Topics: Aging; Animals; Female; Hypotonic Solutions; Intracellular Membranes; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Rats; Rats, Wistar; Rotenone; Sex Characteristics | 1993 |
L-pipecolic acid oxidation in rat: subcellular localization and developmental study.
Topics: Aging; Animals; Antimycin A; Brain; Diethylhexyl Phthalate; Enzyme Induction; Glucagon; Liver; Male; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Sprague-Dawley; Rotenone; Subcellular Fractions | 1993 |
Inhibitor sensitivity of respiratory complex I in human platelets: a possible biomarker of ageing.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Blood Platelets; Electron Transport Complex I; Enzyme Inhibitors; Female; Humans; Mitochondria; NADH, NADPH Oxidoreductases; Rotenone | 1996 |
Decrease of rotenone inhibition is a sensitive parameter of complex I damage in brain non-synaptic mitochondria of aged rats.
Topics: Aging; Animals; Cerebral Cortex; DNA, Mitochondrial; Enzyme Inhibitors; Male; Mitochondria; Multienzyme Complexes; NAD; NAD(P)H Dehydrogenase (Quinone); NADH, NADPH Oxidoreductases; Neuroglia; Neurons; Rats; Rats, Wistar; Rotenone; Synapses | 1997 |
Effect of ATP depletion on the palmitoylation of myelin proteolipid protein in young and adult rats.
Topics: Acylation; Adenosine Triphosphate; Aging; Animals; Brain; Cycloheximide; Female; Kinetics; Male; Mitochondria; Myelin Proteolipid Protein; Oligomycins; Palmitic Acid; Peptide Mapping; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Rotenone | 1999 |
Visualization of mitochondrial oxygen fixation in brain slices by gas-tissue autoradiography.
Topics: Aging; Animals; Autoradiography; Brain; Electron Transport; Energy Metabolism; In Vitro Techniques; Male; Mitochondria; Oxygen; Oxygen Consumption; Oxygen Radioisotopes; Rats; Rats, Wistar; Reactive Oxygen Species; Rotenone; Tomography, Emission-Computed | 1999 |
Mitochondrial respiration and triiodothyronine concentration in liver from postpubertal and adult rats.
Topics: Adenosine Triphosphate; Aging; Animals; Cell Respiration; Cytochrome c Group; Electron Transport Complex III; Electron Transport Complex IV; Hydroquinones; Liver; Male; Mitochondria; Rats; Rats, Wistar; Rotenone; Succinate Dehydrogenase; Succinic Acid; Triiodothyronine; Uncoupling Agents | 2001 |
Light-dependent gene expression for proteins in the respiratory chain of potato leaves.
Topics: Aging; Blotting, Western; Circadian Rhythm; Darkness; Electron Transport; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genes, Plant; Light; Mitochondria; NAD; NADH Dehydrogenase; NADP; Oxidation-Reduction; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Plant; Rotenone; Solanum tuberosum | 2001 |
Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging.
Topics: Age Factors; Aging; Animals; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Enzyme Inhibitors; Male; Mitochondria, Liver; NAD; NADH, NADPH Oxidoreductases; Oxidative Phosphorylation; Oxidoreductases; Oxygen Consumption; Rats; Rats, Wistar; Rotenone | 2002 |
Cadmium toxicity and liver mitochondria. II. Protective effect of hepatic soluble fraction against cadmium-induced mitochondrial dysfunction.
Topics: Adenosine Diphosphate; Aging; Animals; Cadmium; Cytochromes; Cytosol; Liver; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rotenone; Spironolactone; Succinates | 1978 |
Carnitine palymityltransferase in neonatal and adult heart and liver mitochondria. Effect of phospholipase C treatment.
Topics: Acyltransferases; Aging; Animals; Animals, Newborn; Carnitine; Cytochrome Reductases; Kinetics; Liver; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; Oxygen Consumption; Palmitic Acids; Phospholipases; Rats; Rotenone | 1975 |
Electron transport in sarcoplasmic reticulum of fast and slow muscles.
Topics: Aging; Animals; Animals, Newborn; Chickens; Chlorine; Cytochromes; Electron Transport; Endoplasmic Reticulum; Ferricyanides; Indophenol; Microsomes; Muscles; NAD; NADP; Oxidoreductases; Polarography; Rabbits; Rats; Rotenone; Spectrophotometry | 1971 |