Page last updated: 2024-09-04

rostafuroxin and Blood Pressure, High

rostafuroxin has been researched along with Blood Pressure, High in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (11.11)	18.2507
2000's	11 (61.11)	29.6817
2010's	5 (27.78)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bianchi, G; Cerri, A; Fedrizzi, G; Ferrari, P; Gobbini, M; Melloni, P; Quadri, L; Sputore, S; Torri, M	1
Rossoni, LV; Wenceslau, CF	1
Bianchi, G; Ferrandi, M; Ferrari, P; Manunta, P; Molinari, I; Rastaldi, MP	1
Ferrari, P	1
Argiolas, G; Bianchi, G; Carpini, SD; Citterio, L; Cusi, D; Ferrandi, M; Ferrari, P; Glorioso, N; Lanzani, C; Macciardi, F; Manunta, P; Messaggio, E; Salvi, E; Staessen, JA; Tripodi, G; Valentini, G	1
Bacchieri, A; Barton, J; Bianchi, G; Citterio, L; de Leeuw, PW; Dłużniewski, M; Espositi, ED; Ferrari, P; Glorioso, N; Januszewicz, A; Kawecka-Jaszcz, K; Lanzani, C; Manunta, P; Milyagin, V; Nikitin, Y; Souček, M; Staessen, JA; Stolarz-Skrzypek, K; Thijs, L; Timio, M; Tykarski, A; Valentini, G	1
Barassi, P; Bianchi, G; Duzzi, L; Ferrandi, M; Ferrari, P; Minotti, E; Molinari, I	1
Caulfield, MJ; Garcia, EA; Munroe, PB; Newhouse, S	1
Acceto, R; Bacchieri, A; Bianchi, G; Brand, E; Burnier, M; Celis, H; Citterio, L; de Leeuw, PW; Ferrari, P; Filipovský, J; Fournier, A; Kawecka-Jaszcz, K; Kuznetsova, T; Manunta, P; Nikitin, Y; O'Brien, ET; Redón, J; Staessen, JA; Thijs, L; Valentini, G	1
Barassi, P; Bianchi, G; Ferrandi, M; Ferrari, P; Minotti, E; Molinari, I; Torielli, L; Tripodi, G	1
Bianchi, G; Ferrandi, M; Ferrari, P; Valentini, G	1
Ferrandi, M; Ferrari, P; Manunta, P; Messaggio, E	1
Iwamoto, T; Kita, S	1
Bianchi, G; Ferrandi, M; Ferrari, P; Manunta, P; Valentini, G	1
Bianchi, G; Ferrandi, M; Ferrari, P; Molinari, I	1
Bianchi, G; Ferrandi, M; Ferrari, P; Melloni, P; Minotti, E; Padoani, G; Torielli, L; Tripodi, G	1
Bianchi, G; Ferrandi, M; Ferrari, P; Torielli, L; Tripodi, G	1
Schoner, W	1

Reviews

9 review(s) available for rostafuroxin and Blood Pressure, High

Article	Year
Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension. Biochimica et biophysica acta, 2010, Volume: 1802, Issue:12 Topics: Androstanols; Animals; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Clinical Trials, Phase II as Topic; Disease Models, Animal; ErbB Receptors; Humans; Hypertension; Kidney; Mutation; Ouabain; Polymorphism, Genetic; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; src-Family Kinases	2010
Genes and hypertension. Current pharmaceutical design, 2003, Volume: 9, Issue:21 Topics: Androstanols; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Carboxypeptidases; Genomics; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Minor Histocompatibility Antigens; Oligonucleotide Array Sequence Analysis; Peptidyl-Dipeptidase A; Pharmacogenetics; Protein Serine-Threonine Kinases; Renin-Angiotensin System; WNK Lysine-Deficient Protein Kinase 1	2003
Ouabain antagonists as antihypertensive agents. Current pharmaceutical design, 2005, Volume: 11, Issue:25 Topics: Androstanols; Animals; Antihypertensive Agents; Humans; Hypertension; Ouabain; Rats; Rats, Inbred SHR; Sodium-Potassium-Exchanging ATPase	2005
Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension. American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 290, Issue:3 Topics: Androstanols; Animals; Antihypertensive Agents; Blood Vessels; Calmodulin-Binding Proteins; Humans; Hypertension; Kidney; Ouabain; Sodium-Potassium-Exchanging ATPase; Treatment Outcome	2006
A new antihypertensive agent that antagonizes the prohypertensive effect of endogenous ouabain and adducin. Cardiovascular & hematological agents in medicinal chemistry, 2006, Volume: 4, Issue:1 Topics: Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Humans; Hypertension; Ouabain; Risk Factors; Sodium Chloride; Sodium-Potassium-Exchanging ATPase	2006
Hypertension, Na+/Ca2+ exchanger, and Na+, K+-ATPase. Kidney international, 2006, Volume: 69, Issue:12 Topics: Androstanols; Aniline Compounds; Animals; Blood Pressure; Calcium; Cardiac Glycosides; Cardiovascular System; Cell Membrane; Humans; Hypertension; Kidney; Muscle, Smooth, Vascular; Ouabain; Phenyl Ethers; Protein Binding; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Vasoconstriction	2006
Ouabain-dependent signaling in caveolae as a novel therapeutic target for hypertension. Cellular and molecular biology (Noisy-le-Grand, France), 2006, Dec-30, Volume: 52, Issue:8 Topics: Androstanols; Animals; Antihypertensive Agents; Calmodulin-Binding Proteins; Caveolae; Humans; Hypertension; Ouabain; Rats; Signal Transduction	2006
PST 2238: a new antihypertensive compound that modulates the Na-K pump 'in vivo' and 'in vitro'. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: Androstanols; Animals; Antihypertensive Agents; Biological Transport; Humans; Hypertension; In Vitro Techniques; Sodium-Potassium-Exchanging ATPase	2000
Endogenous cardiotonic steroids. Cellular and molecular biology (Noisy-le-Grand, France), 2001, Volume: 47, Issue:2 Topics: Androstanols; Animals; Antihypertensive Agents; Bufanolides; Cardenolides; Cardiac Glycosides; Cardiotonic Agents; Enzyme Inhibitors; Heart; Humans; Hypertension; Molecular Structure; Ouabain; Sodium-Potassium-Exchanging ATPase	2001

Trials

3 trial(s) available for rostafuroxin and Blood Pressure, High

Article	Year
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies. Science translational medicine, 2010, Nov-24, Volume: 2, Issue:59 Topics: Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Female; Genetic Loci; Humans; Hydrochlorothiazide; Hypertension; Intramolecular Transferases; Kidney; Losartan; Male; Middle Aged; Mutant Proteins; Ouabain; Placebos; Polymorphism, Single Nucleotide; Systole; Time Factors; Transfection	2010
Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. Trials, 2011, Jan-14, Volume: 12 Topics: Adult; Aldosterone; Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Cross-Over Studies; Double-Blind Method; Europe; Female; Humans; Hypertension; Male; Middle Aged; Mutation; Ouabain; Renin; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors; Treatment Outcome	2011
OASIS-HT: design of a pharmacogenomic dose-finding study. Pharmacogenomics, 2005, Volume: 6, Issue:7 Topics: Administration, Oral; Adult; Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Molecular Conformation; Ouabain; Risk Factors; Time Factors; Treatment Outcome	2005

Other Studies

6 other study(ies) available for rostafuroxin and Blood Pressure, High

Article	Year
17 beta-(3-furyl)-5 beta-androstane-3 beta, 14 beta, 17 alpha-triol (PST 2238). A very potent antihypertensive agent with a novel mechanism of action. Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11 Topics: Androstanols; Animals; Antihypertensive Agents; Blood Pressure; Enzyme Inhibitors; Hypertension; Kinetics; Molecular Structure; Ouabain; Rats; Rats, Mutant Strains; Sodium-Potassium-Exchanging ATPase	1997
Rostafuroxin ameliorates endothelial dysfunction and oxidative stress in resistance arteries from deoxycorticosterone acetate-salt hypertensive rats: the role of Na+K+-ATPase/ cSRC pathway. Journal of hypertension, 2014, Volume: 32, Issue:3 Topics: Androstanols; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 2; Desoxycorticosterone Acetate; Endothelium, Vascular; Humans; Hypertension; Male; Mesenteric Arteries; NADPH Oxidases; Ouabain; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Vascular Resistance; Vasodilation	2014
Rostafuroxin protects from podocyte injury and proteinuria induced by adducin genetic variants and ouabain. The Journal of pharmacology and experimental therapeutics, 2014, Volume: 351, Issue:2 Topics: Androstanols; Animals; Antihypertensive Agents; Calmodulin-Binding Proteins; Disease Models, Animal; Female; Genetic Variation; Hypertension; Kidney; Male; Mice; Mice, Knockout; Ouabain; Podocytes; Proteinuria; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase	2014
PST 2238: a new antihypertensive compound that modulates renal Na-K pump function without diuretic activity in Milan hypertensive rats. Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:6 Topics: Androstanols; Animals; Blood Pressure; Diuresis; Hydrochlorothiazide; Hypertension; Kidney; Rats; Sodium-Potassium-Exchanging ATPase	2002
Targeting Ouabain- and Adducin-dependent mechanisms of hypertension and cardiovascular remodeling as a novel pharmacological approach. Medical hypotheses, 2007, Volume: 68, Issue:6 Topics: Androstanols; Animals; Antihypertensive Agents; Calmodulin-Binding Proteins; Cardiovascular System; Humans; Hypertension; Models, Cardiovascular; Ouabain; Sodium-Potassium-Exchanging ATPase	2007
PST 2238: A new antihypertensive compound that modulates Na,K-ATPase in genetic hypertension. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3 Topics: Androstanols; Animals; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Heart Rate; Hypertension; Kidney Medulla; Male; Mutation; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Transfection	1999