Page last updated: 2024-08-25

rosiglitazone and Weight Gain

rosiglitazone has been researched along with Weight Gain in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	42 (64.62)	29.6817
2010's	21 (32.31)	24.3611
2020's	2 (3.08)	2.80

Authors

Authors	Studies
Berger, JP; Doebber, TW; Forrest, MJ; Jones, AB; Liu, K; Macnaul, KL; Moller, DE; Xu, L; Zhou, G	1
Broderick, CL; Canada, E; Etgen, GJ; Gonzalez, I; Lamar, J; Mantlo, N; Montrose-Rafizadeh, C; Oldham, BA; Osborne, JJ; Shi, Q; Winneroski, LL; Xie, C; Xu, Y; York, J; Yumibe, N; Zink, R	1
Broderick, CL; Etgen, GJ; Gonzalez, IC; Iradier, F; Lamar, J; Mantlo, N; Montrose-Rafizadeh, C; Oldham, BA; Winneroski, LL; Xu, Y; York, J; Yumibe, N; Zink, R	1
Kagechika, K; Kubo, H; Shibata, Y; Usui, H; Yamaguchi, M	1
Chen, Y; Feng, L; Huang, C; Jin, L; Li, Y; Li, YM; Lu, S; Song, K; Xue, H; Zhang, J; Zhao, Y; Zheng, Z	1
Ahsan, W; Alam, MS; Albratty, M; Alhazmi, HA; Azam, F; Haque, A; Meraya, AM; Najmi, A; Taha, MME; Thangavel, N	1
Achenbach, A; Amri, EZ; Atkinson, DL; Boudina, S; Bowman, F; Buffolo, M; Chaurasia, B; Ferhat, M; Franklin, S; Holland, WL; Ilkun, O; Makaju, A; Pires, KM	1
Rimbach, G; Schrader, E; Wein, S; Wolffram, S	1
Chen, R; Jia, Z; Kakizoe, Y; Liu, G; Liu, M; Sun, Y; Yang, B; Yang, KT; Yang, T; Zhou, L; Zhou, S	1
Chang, YG; Hu, SW; Li, ZJ; Tian, YY; Wang, YM; Xue, CH	1
Alam, Y; Batz, F; Fu, Y; Gerasimova, M; Hummler, E; Kuczkowski, A; Ronzaud, C; Sanders, PW; Vallon, V	1
Pugalendi, KV; Radhiga, T; Sundaresan, A	1
Guo, DF; Liu, X; Lu, KT; Mukohda, M; Rahmouni, K; Sigmund, CD; Stump, M	1
Gu, H; Hinds, TD; Khuder, SS; Lecka-Czernik, B; Najjar, SM; Qiu, B; Russo, L; Sanchez, ER; Stechschulte, LA; Warrier, M; Xu, Y; Yong, W; Zhang, M	1
Waksman, JC	1
Benani, A; Carmona, MC; Casteilla, L; Dacquet, C; Flajollet, S; Galinier, A; Jeanson, Y; Ktorza, A; Lefebvre, B; Lefebvre, P; Louche, K; Pénicaud, L	1
Bugaj, V; Cunard, R; Dechenes, G; Hummler, E; Pochynyuk, O; Rieg, T; Rossier, B; Schroth, J; Stockand, J; Vallon, V	1
Barbosa Aguila, M; de Souza Mendonca, L; Evangelista Carneiro, R; Fernandes-Santos, C; Mandarim-de-Lacerda, CA	1
Maldonado-Lutomirsky, M; Niggli, M; Rosenstock, J	1
Feng, CR; He, QJ; Lou, YJ; Wu, HS; Yang, B; Zhou, CX; Zhu, DF	1
Haffner, SM; Herman, WH; Holman, RR; Kahn, SE; Kravitz, BG; Lachin, JM; Paul, G; Viberti, G; Yu, D; Zinman, B	1
Bak, EJ; Cha, JH; Kim, JM; Park, HG; Yoo, YJ	1
Argo, TR; Housel, AK; Waterbury, N	1
Limor, R; Oron, Y; Rosenthal, T; Stern, N; Younis, F; Zangen, S	1
DeFronzo, RA; Glass, LC; Lewis, MS; Maggs, D; Qu, Y; Triplitt, C	1
Chen, YT; Cheng, JT; Chi, TC; Lee, HH; Lo, SH; Yeh, CH	1
Liu, Q; Niu, YJ; Tao, RY; Tian, JY; Ye, F; Zhu, HB; Zhu, P	1
Grayson, BE; Li, B; Matter, EK; Ryan, KK; Seeley, RJ; Woods, SC	1
Bandyopadhyay, G; Fan, W; Gayen, JR; Li, P; Lu, M; Mahata, SK; Nalbandian, S; Olefsky, JM; Sarruf, DA; Schwartz, MW; Sharma, S; Talukdar, S; Webster, NJ	1
Abdullah, SM; Armstead, SI; Ayers, CR; de Lemos, JA; Gore, MO; Khera, A; McGavock, J; McGuire, DK; Narang, N; See, R; Snell, PG; Stream, A	1
Banks, AS; Bruning, JB; Busby, SA; Cameron, MD; Chalmers, MJ; Choi, JH; Griffin, PR; He, Y; Jurczak, MJ; Kamenecka, TM; Kumar, N; Kuruvilla, DS; Laznik, D; Marciano, DP; Schürer, SC; Shin, Y; Shulman, GI; Spiegelman, BM; Vidović, D	1
Bayraktar, N; Berberoglu, Z; Demirag, NG; Yazici, AC	1
Doubova, SV; Flores-Hernández, S; Mino-León, D; Reyes-Morales, H	1
Mohan, V; Vidhya, S	1
German, JB; Leiter, EH; Pan, HJ; Reifsnyder, PR; Watkins, SM	1
Cobitz, AR; Haimbach, RE; Jucker, BM; Mayer, ME; Ohlstein, DH; Sarkar, SK; Schaeffer, TR; Smith, SA	1
Gavish, D; Gavish, E; Leibovitz, E; Leibovitz, Z; Matas, D; Matas, Z; Shargorodsky, M; Wainstein, G; Wainstein, J; Zimlichman, R	1
Papoushek, C	1
Kaposzta, Z; Kaski, JC; Markus, HS; Sidhu, JS	1
Avery, MA; Benson, SC; Chittiboyina, A; Desai, P; Ho, CI; Kurtz, TW; Pershadsingh, HA; Pravenec, M; Qi, N; Wang, J	1
Cappleman, JM; Hale, PM; Kaye, W; Khutoryansky, N; McGill, J; Raskin, P; Saad, MF	1
Akbay, E; Aktürk, M; Arslan, M; Ayvaz, G; Cakir, N; Elbeg, S; Karakoç, A; Sancak, B; Taneri, F; Törüner, F	1
Bu, S; Chen, XP; Liu, XL; Wang, N; Xiao, JZ; Yang, WY; Zhao, WH	1
De Champlain, J; Wang, R; Wilson, TW; Wu, L	1
Kazim, M; Levin, F; Marcovici, E; Smith, TJ	1
Bross, A; Carmona, MC; Casteilla, L; Dacquet, C; Desbazeille, M; Louche, K; Nibbelink, M; Pénicaud, L; Prunet, B; Renard, P	1
Raskin, P; Strowig, SM	1
Chow, KM; Lam, CW; Leung, CB; Li, PK; Szeto, CC; Wong, TY	1
Taéron, C	1
Aiello, LP; Clermont, A; Della Vecchia, K; King, GL; Kondo, T; Mastumoto, M; Rask-Madsen, C; Sotiropoulos, KB; Takahashi, J; Yasuda, Y	1
Ahn, CW; Cha, BS; Hur, KY; Kang, ES; Kim, HJ; Kim, SH; Lee, HC; Lee, HJ; Shim, WS	1
Berthiaume, M; Deshaies, Y; Festuccia, WT; Gélinas, Y; Laplante, M	1
Johansen, OE; Jørgensen, AP	1
Ishida, Y; Ito, M; Kakutani, M; Matsushita, M; Nishiu, J; Shibata, T; Shindo, M	1
Scherbaum, WA	1
Klinkner, DB; Lim, HJ; Oldham, KT; Sander, TL; Strawn, EY	1
Haffner, SM; Heise, MA; Herman, WH; Holman, RR; Jones, NP; Kahn, SE; Kravitz, BG; Lachin, JM; O'Neill, MC; Viberti, G; Zinman, B	1
Nathan, DM	1
Bianchi, A; Jouzeau, JY; Koufany, M; Moulin, D; Muresan, M; Netter, P; Sebillaud, S; Weryha, G	1
Chen, JL; Escaron, P; Furukawa, N; Learned, RM; Lee, G; Li, Y; Lindstrom, M; Liu, J; Liu, X; Plotnikova, O; Prasad, V; Walker, N; Wang, Z; Weiszmann, J; Xu, H	1
Krische, D	1
Kenyon, CJ; Livingstone, DE; Walker, BR	1
Cawthorne, MA; Emilsson, V; Heyman, R; Liu, YL; O'Dowd, J; Sennitt, M; Wang, S	1
Isley, WL	1
Scheen, AJ	1

Reviews

5 review(s) available for rosiglitazone and Weight Gain

Article	Year
Cardiovascular risk of rosiglitazone: another perspective. The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:12 Topics: Adverse Drug Reaction Reporting Systems; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Monitoring; Edema; Humans; Hypoglycemic Agents; Patient Selection; Risk Factors; Rosiglitazone; Thiazolidinediones; Weight Gain	2008
Can metformin or rosiglitazone reduce metabolic side effects associated with atypical antipsychotics? Issues in mental health nursing, 2009, Volume: 30, Issue:12 Topics: Antipsychotic Agents; Humans; Hypoglycemic Agents; Metabolic Syndrome; Metformin; Randomized Controlled Trials as Topic; Risk Factors; Rosiglitazone; Schizophrenia; Thiazolidinediones; Weight Gain	2009
The "glitazones": rosiglitazone and pioglitazone. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2003, Volume: 25, Issue:10 Topics: Contraindications; Diabetes Mellitus, Type 2; Drug Interactions; Female; Heart Failure; Humans; Hypoglycemic Agents; Lactation; Pioglitazone; Pregnancy; Risk Factors; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Weight Gain	2003
The glitazones: proceed with caution. The Western journal of medicine, 2000, Volume: 173, Issue:1 Topics: Chromans; Diabetes Mellitus, Type 2; Drug Evaluation; Humans; Hypoglycemic Agents; Liver; Pioglitazone; Prognosis; Rosiglitazone; Safety; Thiazoles; Thiazolidinediones; Troglitazone; Weight Gain	2000
[Medication of the month. Rosiglitazone (Avandia)]. Revue medicale de Liege, 2002, Volume: 57, Issue:4 Topics: Administration, Oral; Diabetes Mellitus, Type 2; Heart Failure; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Prognosis; Risk Factors; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain	2002

Trials

10 trial(s) available for rosiglitazone and Weight Gain

Article	Year
Rosiglitazone decreases C-reactive protein to a greater extent relative to glyburide and metformin over 4 years despite greater weight gain: observations from a Diabetes Outcome Progression Trial (ADOPT). Diabetes care, 2010, Volume: 33, Issue:1 Topics: Adult; Aged; C-Reactive Protein; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Rosiglitazone; Thiazolidinediones; Time; Treatment Outcome; Weight Gain	2010
Effects of exenatide plus rosiglitazone on beta-cell function and insulin sensitivity in subjects with type 2 diabetes on metformin. Diabetes care, 2010, Volume: 33, Issue:5 Topics: Aged; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Exenatide; Female; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Peptides; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Venoms; Weight Gain	2010
Assessment of cardiac structure and function in patients without and with peripheral oedema during rosiglitazone treatment. Diabetes & vascular disease research, 2011, Volume: 8, Issue:2 Topics: Aged; Biomarkers; Chi-Square Distribution; Diabetes Mellitus, Type 2; Edema; Exercise Test; Female; Heart Failure; Hematocrit; Humans; Hypoglycemic Agents; Magnetic Resonance Imaging; Male; Middle Aged; Myocardium; Natriuretic Peptide, Brain; Oxygen Consumption; Plasma Volume; Prospective Studies; Rosiglitazone; Serum Albumin; Single-Blind Method; Stroke Volume; Texas; Thiazolidinediones; Time Factors; Ventricular Function; Weight Gain	2011
Rosiglitazone decreases fasting plasma peptide YY3-36 in type 2 diabetic women: a possible role in weight gain? Acta diabetologica, 2012, Volume: 49 Suppl 1 Topics: Adult; Aged; Diabetes Mellitus, Type 2; Down-Regulation; Fasting; Female; Humans; Middle Aged; Peptide YY; Rosiglitazone; Thiazolidinediones; Weight Gain	2012
Treatment with rosiglitazone reduces hyperinsulinemia and improves arterial elasticity in patients with type 2 diabetes mellitus. American journal of hypertension, 2003, Volume: 16, Issue:8 Topics: Adult; Aged; Arteries; Blood Glucose; Blood Pressure; Compliance; Diabetes Mellitus, Type 2; Elasticity; Female; Heart Rate; Humans; Hyperinsulinism; Hypoglycemic Agents; Male; Middle Aged; Risk Factors; Rosiglitazone; Thiazolidinediones; Vascular Resistance; Weight Gain	2003
Effect of rosiglitazone on common carotid intima-media thickness progression in coronary artery disease patients without diabetes mellitus. Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:5 Topics: Adrenergic beta-Antagonists; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Carotid Artery Diseases; Carotid Artery, Common; Cohort Studies; Coronary Artery Disease; Disease Progression; Double-Blind Method; Drug Synergism; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Insulin Resistance; Lipids; Male; Middle Aged; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Ultrasonography; Weight Gain	2004
Combination therapy for type 2 diabetes: repaglinide plus rosiglitazone. Diabetic medicine : a journal of the British Diabetic Association, 2004, Volume: 21, Issue:4 Topics: Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Piperidines; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Weight Gain	2004
The effect of rosiglitazone on overweight subjects with type 1 diabetes. Diabetes care, 2005, Volume: 28, Issue:7 Topics: Adult; Blood Glucose; Body Mass Index; Body Size; C-Peptide; Diabetes Mellitus, Type 1; Double-Blind Method; Ethnicity; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Obesity; Placebos; Rosiglitazone; Thiazolidinediones; Weight Gain	2005
Rosiglitazone reduces insulin requirement and C-reactive protein levels in type 2 diabetic patients receiving peritoneal dialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:4 Topics: Aged; C-Reactive Protein; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Injections, Subcutaneous; Insulin; Insulin Resistance; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Rosiglitazone; Thiazolidinediones; Uremia; Weight Gain	2005
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. The New England journal of medicine, 2006, Dec-07, Volume: 355, Issue:23 Topics: Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Kaplan-Meier Estimate; Male; Metformin; Middle Aged; Proportional Hazards Models; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Waist-Hip Ratio; Weight Gain	2006

Other Studies

50 other study(ies) available for rosiglitazone and Weight Gain

Article	Year
Discovery of a novel series of peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes and dyslipidemia. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: 3T3-L1 Cells; Animals; Blood Glucose; Carrier Proteins; Chlorocebus aethiops; Cholesterol; COS Cells; Diabetes Mellitus, Type 2; Dogs; Fatty Acid-Binding Proteins; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Isoxazoles; Mice; Mice, Obese; PPAR alpha; PPAR gamma; Propionates; Radioligand Assay; RNA, Messenger; Structure-Activity Relationship; Transcriptional Activation; Triglycerides; Weight Gain	2005
Design and synthesis of dual peroxisome proliferator-activated receptors gamma and delta agonists as novel euglycemic agents with a reduced weight gain profile. Journal of medicinal chemistry, 2006, Sep-21, Volume: 49, Issue:19 Topics: Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Drug Design; Dyslipidemias; Female; Humans; Hypoglycemic Agents; Male; Mice; Phenyl Ethers; Phenylpropionates; PPAR alpha; PPAR delta; PPAR gamma; Radioligand Assay; Stereoisomerism; Transcriptional Activation; Weight Gain	2006
Design and synthesis of a novel class of dual PPARgamma/delta agonists. Bioorganic & medicinal chemistry letters, 2007, Feb-15, Volume: 17, Issue:4 Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Drug Design; Female; Half-Life; Humans; Hypoglycemic Agents; Indicators and Reagents; Insulin; Male; PPAR delta; PPAR gamma; Rats; Rats, Sprague-Dawley; Rats, Zucker; Rosiglitazone; Structure-Activity Relationship; Thiazolidinediones; Weight Gain	2007
Design, synthesis and evaluation of novel zwitterionic compounds as PPARα/γ dual agonists (1). Bioorganic & medicinal chemistry letters, 2012, Dec-01, Volume: 22, Issue:23 Topics: Animals; Blood Glucose; Drug Design; Mice; PPAR alpha; PPAR gamma; Structure-Activity Relationship; Thiazolidinediones; Triglycerides; Weight Gain	2012
Identification of an allosteric hotspot for additive activation of PPARγ in antidiabetic effects. Science bulletin, 2021, 08-15, Volume: 66, Issue:15 Topics: Animals; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Mice; PPAR gamma; Rosiglitazone; Thiazolidinediones; Weight Gain	2021
Synthesis, molecular docking, and in vivo antidiabetic evaluation of new benzylidene-2,4-thiazolidinediones as partial PPAR-γ agonists. Scientific reports, 2023, 11-14, Volume: 13, Issue:1 Topics: Animals; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Ligands; Mice; Molecular Docking Simulation; PPAR gamma; PPAR-gamma Agonists; Rosiglitazone; Thiazolidinediones; Weight Gain	2023
Identification of a Paracrine Signaling Mechanism Linking CD34 Cell reports, 2019, 10-08, Volume: 29, Issue:2 Topics: Adipogenesis; Adipose Tissue, White; Animals; Antigens, CD34; Bone Morphogenetic Protein 4; Fibroblasts; Insulin Resistance; Intra-Abdominal Fat; Male; Mice, Inbred C57BL; Muscle, Smooth; Paracrine Communication; Phenotype; Rosiglitazone; Signal Transduction; Solubility; Stem Cells; Weight Gain	2019
Oral green tea catechins transiently lower plasma glucose concentrations in female db/db mice. Journal of medicinal food, 2013, Volume: 16, Issue:4 Topics: Adiponectin; Adipose Tissue; Animals; Anti-Inflammatory Agents; Blood Glucose; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Flavonoids; Hyperglycemia; Hypoglycemic Agents; Inflammation; Intercellular Adhesion Molecule-1; Mice; Mice, Knockout; Mice, Obese; Obesity; Phytotherapy; Plant Extracts; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha; Weight Gain	2013
Increased susceptibility of db/db mice to rosiglitazone-induced plasma volume expansion: role of dysregulation of renal water transporters. American journal of physiology. Renal physiology, 2013, Nov-15, Volume: 305, Issue:10 Topics: Animals; Aquaporin 2; Aquaporin 3; Biological Transport; Blood Glucose; Body Water; Diabetes Mellitus; Disease Models, Animal; Diuresis; Humans; Hypoglycemic Agents; Kidney; Male; Mice; Natriuresis; Osmolar Concentration; Plasma Volume; PPAR gamma; Rosiglitazone; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Solute Carrier Family 12, Member 1; Thiazolidinediones; Triglycerides; Water-Electrolyte Balance; Water-Electrolyte Imbalance; Weight Gain	2013
Fucosylated chondroitin sulfate from sea cucumber improves glucose metabolism and activates insulin signaling in the liver of insulin-resistant mice. Journal of medicinal food, 2014, Volume: 17, Issue:7 Topics: Adipose Tissue; Animals; Blood Glucose; Carbohydrate Metabolism; Chondroitin Sulfates; Diet, High-Fat; Dietary Sucrose; Drug Synergism; Glycogen; Glycogen Synthase; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Liver; Male; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Rosiglitazone; Sea Cucumbers; Signal Transduction; Thiazolidinediones; Weight Gain	2014
PPARγ agonist-induced fluid retention depends on αENaC expression in connecting tubules. Nephron, 2015, Volume: 129, Issue:1 Topics: Animals; Body Fluids; Diet, Sodium-Restricted; Edema; Epithelial Sodium Channels; Gene Knockdown Techniques; Humans; Hypoglycemic Agents; Kidney Tubules, Collecting; Male; Mice; Mice, Knockout; PPAR gamma; Rosiglitazone; Thiazolidinediones; Weight Gain	2015
Ursolic acid and rosiglitazone combination improves insulin sensitivity by increasing the skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat diet-fed C57BL/6J mice. Journal of physiology and biochemistry, 2016, Volume: 72, Issue:2 Topics: Animals; Anti-Obesity Agents; Antioxidants; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Therapy, Combination; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Rosiglitazone; Second Messenger Systems; Thiazolidinediones; Triterpenes; Ursolic Acid; Weight Gain	2016
Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance. Physiological genomics, 2016, 07-01, Volume: 48, Issue:7 Topics: 3T3 Cells; Adipogenesis; Animals; Body Weight; Brain; Cell Line; Diet, High-Fat; Energy Metabolism; Female; HEK293 Cells; Homeostasis; Humans; Leptin; Male; Mice; Neurons; Obesity; PPAR gamma; Pro-Opiomelanocortin; Rosiglitazone; Thiazolidinediones; Weight Gain	2016
FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPARγ Agonist Rosiglitazone. Endocrinology, 2016, Volume: 157, Issue:10 Topics: Adiposity; Animals; Energy Metabolism; Fatty Liver; Glucose Intolerance; Intra-Abdominal Fat; Lipid Metabolism; Lipids; Male; Mice, Knockout; Obesity; PPAR gamma; Rosiglitazone; Tacrolimus Binding Proteins; Thiazolidinediones; Weight Gain	2016
Coadministration of coenzyme Q prevents rosiglitazone-induced adipogenesis in ob/ob mice. International journal of obesity (2005), 2009, Volume: 33, Issue:2 Topics: Adipogenesis; Animals; Drug Therapy, Combination; Energy Metabolism; Glucose Tolerance Test; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Ubiquinone; Weight Gain	2009
Thiazolidinedione-induced fluid retention is independent of collecting duct alphaENaC activity. Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:4 Topics: Animals; Epithelial Sodium Channels; Kidney Medulla; Kidney Tubules, Collecting; Mice; Patch-Clamp Techniques; Pioglitazone; Rosiglitazone; Thiazolidinediones; Weight Gain	2009
Rosiglitazone aggravates nonalcoholic Fatty pancreatic disease in C57BL/6 mice fed high-fat and high-sucrose diet. Pancreas, 2009, Volume: 38, Issue:3 Topics: Adipose Tissue; Animals; Bezafibrate; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Sucrose; Energy Metabolism; Fenofibrate; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Obesity; Pancreatic Diseases; PPAR alpha; PPAR-beta; Rosiglitazone; Thiazolidinediones; Weight Gain	2009
Long-term 2-year safety and efficacy of vildagliptin compared with rosiglitazone in drug-naïve patients with type 2 diabetes mellitus. Diabetes, obesity & metabolism, 2009, Volume: 11, Issue:6 Topics: Adamantane; Adult; Aged; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Edema; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipids; Male; Middle Aged; Nitriles; Pyrrolidines; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Vildagliptin; Weight Gain	2009
Insulin sensitizing activity of ethyl acetate fraction of Acorus calamus L. in vitro and in vivo. Journal of ethnopharmacology, 2009, Jun-22, Volume: 123, Issue:2 Topics: Acetates; Acorus; Administration, Oral; Animals; Diabetes Mellitus, Experimental; Glucose; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Medicine, Traditional; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle Fibers, Skeletal; Plant Extracts; Rosiglitazone; Thiazolidinediones; Weight Gain	2009
Inhibitory effect of evodiamine alone and in combination with rosiglitazone on in vitro adipocyte differentiation and in vivo obesity related to diabetes. International journal of obesity (2005), 2010, Volume: 34, Issue:2 Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Cell Differentiation; Cell Line; Dietary Fats; Drug Therapy, Combination; Hypoglycemic Agents; Insulin; Liver; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Quinazolines; Rosiglitazone; Thiazolidinediones; Weight Gain	2010
Telmisartan ameliorates hyperglycemia and metabolic profile in nonobese Cohen-Rosenthal diabetic hypertensive rats via peroxisome proliferator activator receptor-gamma activation. Metabolism: clinical and experimental, 2010, Volume: 59, Issue:8 Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Humans; Hyperglycemia; Hypertension; Insulin; Insulin Resistance; Leptin; PPAR gamma; Rats; Rats, Inbred SHR; Rosiglitazone; Telmisartan; Thiazolidinediones; Tumor Necrosis Factor-alpha; Weight Gain	2010
Effects of metformin on rosiglitazone-induced cardiac hypertrophy in mice. Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:9 Topics: Animals; Body Weight; Cardiomegaly; Drug Therapy, Combination; Eating; Male; Metformin; Mice; Mice, Inbred BALB C; Obesity; Rosiglitazone; Thiazolidinediones; Weight Gain	2010
Improvement on lipid metabolic disorder by 3'-deoxyadenosine in high-fat-diet-induced fatty mice. The American journal of Chinese medicine, 2010, Volume: 38, Issue:6 Topics: Animals; Area Under Curve; Cordyceps; Deoxyadenosines; Dietary Fats; Disease Models, Animal; Fenofibrate; Glucose; Glucose Clamp Technique; Glucose Intolerance; Insulin; Insulin Resistance; Lipid Metabolism; Lipid Metabolism Disorders; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Phytotherapy; Rosiglitazone; Thiazolidinediones; Weight Gain	2010
A role for central nervous system PPAR-γ in the regulation of energy balance. Nature medicine, 2011, Volume: 17, Issue:5 Topics: Animals; Blood-Brain Barrier; Central Nervous System; Energy Metabolism; Gene Expression; Humans; Hypoglycemic Agents; Hypothalamus; Male; PPAR gamma; Rats; Rats, Long-Evans; Recombinant Fusion Proteins; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; Weight Gain	2011
Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nature medicine, 2011, Volume: 17, Issue:5 Topics: Aged; Animals; Brain; Diabetes Mellitus, Type 2; Energy Metabolism; Humans; Hypoglycemic Agents; Insulin Resistance; Mice; Mice, Knockout; Middle Aged; Obesity; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones; Weight Gain	2011
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation. Nature, 2011, Sep-04, Volume: 477, Issue:7365 Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Animals; Biphenyl Compounds; Body Fluids; Chlorocebus aethiops; COS Cells; Cyclin-Dependent Kinase 5; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Hypoglycemic Agents; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Models, Molecular; Obesity; Osteogenesis; Phosphorylation; Phosphoserine; PPAR gamma; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Tumor Necrosis Factor-alpha; Weight Gain	2011
Postmarketing pharmacovigilance of adverse drug reactions: the case of rosiglitazone in Mexico. International journal of clinical pharmacology and therapeutics, 2012, Volume: 50, Issue:1 Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Drug Combinations; Edema; Female; Follow-Up Studies; Glyburide; Humans; Hypoglycemic Agents; Male; Medication Adherence; Metformin; Mexico; Middle Aged; Pharmacovigilance; Prospective Studies; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain	2012
Rosiglitazone--useful drug but has side effects. The Journal of the Association of Physicians of India, 2002, Volume: 50 Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Lipids; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain	2002
Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone. Journal of lipid research, 2002, Volume: 43, Issue:11 Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Gene Expression; Heart; Lipid Metabolism; Lipids; Liver; Male; Mice; Mice, Obese; Myocardium; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Weight Gain	2002
Reduction of intramyocellular lipid following short-term rosiglitazone treatment in Zucker fatty rats: an in vivo nuclear magnetic resonance study. Metabolism: clinical and experimental, 2003, Volume: 52, Issue:2 Topics: Animals; Blood Glucose; Insulin; Lipid Metabolism; Lipids; Magnetic Resonance Spectroscopy; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides; Weight Gain	2003
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5 Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Cell Differentiation; Cells, Cultured; Chlorocebus aethiops; Drug Evaluation, Preclinical; Gene Expression Regulation; Imidazoles; Insulin; Irbesartan; Losartan; Male; Mice; Models, Molecular; Myoblasts; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Structure-Activity Relationship; Telmisartan; Tetrazoles; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Triglycerides; Valine; Valsartan; Weight Gain	2004
Effects of PPARgamma and PPARalpha agonists on serum leptin levels in diet-induced obese rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2004, Volume: 36, Issue:4 Topics: Adipose Tissue; Animals; Dietary Fats; Energy Metabolism; Gemfibrozil; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Leptin; Male; Obesity; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Weight Gain	2004
[Effects of rosiglitazone and metformin on insulin resistance in high-fat diet rats]. Zhonghua nei ke za zhi, 2004, Volume: 43, Issue:4 Topics: Animals; Blood Glucose; Dietary Fats; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Random Allocation; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Weight Gain	2004
Beneficial and deleterious effects of rosiglitazone on hypertension development in spontaneously hypertensive rats. American journal of hypertension, 2004, Volume: 17, Issue:9 Topics: Animals; Antihypertensive Agents; Hypertension; Hypertrophy, Left Ventricular; Kidney; Male; Myocardium; Organ Size; Peroxisome Proliferators; PPAR alpha; PPAR gamma; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rosiglitazone; Tachycardia; Thiazolidinediones; Weight Gain	2004
Rosiglitazone-induced proptosis. Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:1 Topics: Diabetes Mellitus, Type 2; Exophthalmos; Eye; Female; Humans; Hypoglycemic Agents; Middle Aged; Rosiglitazone; Thiazolidinediones; Thyroid Function Tests; Tomography, X-Ray Computed; Weight Gain	2005
Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice. International journal of obesity (2005), 2005, Volume: 29, Issue:7 Topics: Animals; Body Composition; Depression, Chemical; Drug Therapy, Combination; Fatty Acids; Fenofibrate; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones; Triglycerides; Weight Gain	2005
[Rosiglitazone]. Revue de l'infirmiere, 2006, Issue:118 Topics: Diabetes Mellitus, Type 1; Drug Monitoring; Humans; Hypoglycemic Agents; Nurse's Role; Patient Education as Topic; Rosiglitazone; Thiazolidinediones; Weight Gain	2006
Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:8 Topics: Adipose Tissue; Animals; Capillary Permeability; Diabetes Mellitus; Edema; Enzyme Activation; Enzyme Inhibitors; Hypoglycemic Agents; Indoles; Male; Maleimides; Mice; Mice, Knockout; Obesity; PPAR gamma; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Receptor, Insulin; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factor A; Weight Gain	2006
The 11482G >A polymorphism in the perilipin gene is associated with weight gain with rosiglitazone treatment in type 2 diabetes. Diabetes care, 2006, Volume: 29, Issue:6 Topics: Carrier Proteins; Diabetes Mellitus, Type 2; DNA Primers; Genetic Variation; Humans; Hypoglycemic Agents; Middle Aged; Perilipin-1; Phosphoproteins; Polymorphism, Single Nucleotide; Rosiglitazone; Thiazolidinediones; Weight Gain	2006
PPARgamma agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control. Diabetologia, 2006, Volume: 49, Issue:10 Topics: Adipose Tissue; Animals; Bucladesine; Energy Intake; Fatty Acid-Binding Proteins; Fatty Acids, Nonesterified; Lipase; Lipolysis; Male; PPAR gamma; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Weight Gain	2006
[Glitazone treatment of type 2 diabetes mellitus]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2006, Aug-10, Volume: 126, Issue:15 Topics: Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Retrospective Studies; Rosiglitazone; Thiazolidinediones; Weight Gain	2006
JTP-426467 acts as a selective antagonist for peroxisome proliferator-activated receptor gamma in vitro and in vivo. Diabetes, obesity & metabolism, 2006, Volume: 8, Issue:5 Topics: Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Benzoxazoles; Blood Glucose; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; HeLa Cells; Humans; Hypoglycemic Agents; Leptin; Male; Mice; Obesity; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Weight Gain	2006
Do patients with type 2 diabetes on peritoneal dialysis need less insulin if they are given rosiglitazone? Nature clinical practice. Nephrology, 2006, Volume: 2, Issue:6 Topics: Aged; C-Reactive Protein; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Injections, Subcutaneous; Insulin; Insulin Resistance; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Rosiglitazone; Thiazolidinediones; Uremia; Weight Gain	2006
An in vivo murine model of rosiglitazone use in pregnancy. Fertility and sterility, 2006, Volume: 86, Issue:4 Suppl Topics: Animals; Animals, Newborn; Blastocyst; Coculture Techniques; Female; Litter Size; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Pregnancy; Pregnancy, Animal; Rosiglitazone; Thiazolidinediones; Tissue Culture Techniques; Weight Gain	2006
Thiazolidinediones for initial treatment of type 2 diabetes? The New England journal of medicine, 2006, Dec-07, Volume: 355, Issue:23 Topics: Algorithms; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Thiazolidinediones; Weight Gain	2006
Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis. Arthritis research & therapy, 2008, Volume: 10, Issue:1 Topics: Adiponectin; Adipose Tissue; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Biomarkers; Bone and Bones; Bone Density; Bone Remodeling; Bone Resorption; Cartilage, Articular; Cytokines; Dose-Response Relationship, Drug; Fever; Fibroblast Growth Factor 2; Hindlimb; Hypoglycemic Agents; Incidence; Male; Pioglitazone; PPAR gamma; Rats; Rats, Inbred Lew; RNA, Messenger; Rosiglitazone; Synovial Membrane; Synovitis; Thiazolidinediones; Weight Gain	2008
T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties. The Journal of biological chemistry, 2008, Apr-04, Volume: 283, Issue:14 Topics: Adipocytes; Adipogenesis; Animals; Benzothiazoles; Binding Sites; Cells, Cultured; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Glucose; Homeostasis; Humans; Hypoglycemic Agents; Ligands; Mice; Models, Molecular; PPAR gamma; Rosiglitazone; Sulfonamides; Thiazolidinediones; Weight Gain	2008
Mechanisms of dysregulation of 11 beta-hydroxysteroid dehydrogenase type 1 in obese Zucker rats. The Journal of endocrinology, 2000, Volume: 167, Issue:3 Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adipose Tissue; Adrenal Glands; Adrenalectomy; Analysis of Variance; Animals; Blood Glucose; Corticosterone; Eating; Hydroxysteroid Dehydrogenases; Hypertrophy; Hypoglycemic Agents; Insulin; Liver; Male; Metformin; Obesity; Omentum; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain	2000
The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat. Metabolism: clinical and experimental, 2000, Volume: 49, Issue:12 Topics: Adipose Tissue, Brown; Animals; Body Weight; Carrier Proteins; Eating; Ion Channels; Membrane Proteins; Membrane Transport Proteins; Mitochondrial Proteins; Nicotinic Acids; Obesity; Proteins; Rats; Rats, Zucker; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Uncoupling Protein 1; Uncoupling Protein 2; Uncoupling Protein 3; Weight Gain	2000
Glitazones, glycemia, and global health status. Diabetes care, 2001, Volume: 24, Issue:12 Topics: Blood Glucose; Health Status; Humans; Hypoglycemic Agents; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain	2001