Page last updated: 2024-08-25

rosiglitazone and Obesity

rosiglitazone has been researched along with Obesity in 288 studies

Research

Studies (288)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (3.47)	18.2507
2000's	162 (56.25)	29.6817
2010's	101 (35.07)	24.3611
2020's	15 (5.21)	2.80

Authors

Authors	Studies
Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM	1
Chen, ML; Leng, Y; Shen, JH; Shen, Y; Tang, J; Xu, TF; Ye, YL; Yin, HZ; Zhou, Z; Zou, HJ	1
Abad, MC; Askari, HB; De, D; Gaul, MD; Geisler, JG; Kasturi, J; Kemmerer, M; Kim, AJ; Lenhard, JM; Lin, L; Liu, J; O'Neill, JC; Patch, RJ; Player, MR; Rentzeperis, D; Searle, LL; Zhu, X	1
Chen, J; Chen, L; Huang, L; Lai, H; Liang, X; Liu, J; Ma, L; Pei, H; Peng, A; Ran, Y; Sang, Y; Wei, Y; Xiang, M; Xie, C	1
Fenaux, M; Halcomb, RL; Jones, CT; Romero, FA; Xu, Y	1
Su, Y; Tang, L; Wang, T; Wang, W; Xiao, Q; Xie, M	1
Ali, R; Allison, BA; Baker, C; Jonas, DE; LeBlanc, ES; Middleton, JC; Riley, S; Vander Schaaf, EB; Voisin, CE	1
Kim, K; Roh, HC; So, J; Strobel, O; Taleb, S; Wann, J	1
Blumberg, B; Chang, RC; Joloya, EM; Li, Z; Shioda, T; Shoucri, BM	1
Amri, EZ; Balas, L; Batrow, PL; Bernoud-Hubac, N; Colson, C; Contu, L; Dieckmann, S; Durand, T; Fourmaux, B; Gautier, N; Klingenspor, M; Langin, D; Rochet, N; Roux, CH; Vigor, C	1
Alexopoulos, SJ; Beretta, M; Byrne, FL; Cantley, J; Chen, SY; Garcia, CJ; Hoehn, KL; Larance, M; Olzomer, EM; Philp, A; Salamoun, JM; Santos, WL; Shah, DP; Smith, GC; Turner, N	1
Appendino, G; Calzado, MA; Eugenia Prados, M; Ferreiro-Vera, C; Garrido-Rodriguez, M; Morrugares, R; Muñoz, E; Nadal, X; Palomares, B; Ruiz-Pino, F; Sánchez-Garrido, MA; Tena-Sempere, M; Vazquez, MJ; Velasco, I	1
Duan, C; Hu, Y; Huang, W; Li, Y; Tan, J; Wang, Q	1
Arya, S; Hansen, KR; Wild, RA	1
Jacobs, C; Kumari, M; Lyubetskaya, A; Roh, HC; Rosen, ED; Taleb, S; Tenen, D; Tsai, LT	1
Harashima, H; Hida, K; Hiradate, R; Khalil, IA; Matsuda, A; Sasaki, M	1
Chen, R; Duan, F; Huang, S; Lin, T; Lv, J; Ma, H; Nie, L; Ren, L; Shan, W; Zhang, J	1
Chen, MT; Gao, DD; Huang, JS; Li, YX; Wang, HY	1
Cordoba-Chacon, J; Diaz-Ruiz, A; Kineman, RD; Lee, SM; Liew, CW; McCann, M; Muratalla, J; Remon-Ruiz, P	1
Babin, PJ; Capilla, E; Gutiérrez, J; Lutfi, E; Navarro, I	1
den Hartigh, LJ; Goodspeed, L; Houston, B; Turk, KE; Wang, S	1
Gu, Z; Liu, Q; Qiang, L; Wang, J; Yu, J; Yu, S; Zhang, Y	1
Beaudoin, MS; Foute-Nelong, J; Gaudio, N; Mutch, DM; Reed, JK; Wright, DC	1
Guo, J; Li, L; Li, X; Wang, L; Wang, Y; Zhang, H; Zhong, T	1
Mahboob, T; Tabassum, A	1
Area-Gomez, E; Chan, M; Creusot, RJ; Fan, L; Fu, W; Ji, R; Kon, N; Kraakman, MJ; Larrea, D; Liu, Q; Namwanje, M; Postigo-Fernandez, J; Qiang, L	1
Kuranaga, T; Ono, Y; Sato, Y; Takatsuki, S; Unno, Y; Wakimoto, T; Yamamoto, H; Yazawa, K	1
Chen, J; Deng, S; Essandoh, K; Fan, GC; Gu, H; Holland, J; Huang, K; Jegga, AG; Li, Y; Liu, T; McNamara, RK; Mu, X; Nakamura, T; Peng, J; Peng, T; Perez-Tilve, D; Wang, B; Wang, X; Yates, E	1
He, L; Kalugotla, G; Razani, B; Sauer, M; Schilling, JD; Tycksen, E; Weber, KJ	1
Arteel, GE; Chartoumpekis, DV; Fazzari, M; Freeman, BA; Guimaraes, DA; Khoo, NKH; Li, L; Shiva, S	1
Nemanich, S; Rani, S; Shoghi, K	1
Rimbach, G; Schrader, E; Wein, S; Wolffram, S	1
Chang, CJ; Liu, IM; Tzeng, TF	1
Han, CT; Hartmann, L; Mayr, JA; Meierhofer, D; Sauer, S; Schroeder, FC; Weidner, C	1
Arnould, T; Geeraert, B; Holvoet, P; Hulsmans, M; Tsatsanis, C	1
Eckel, J; Flachs, P; Hensler, M; Horakova, O; Janovska, P; Jilkova, ZM; Kopecky, J; Medrikova, D; Rossmeisl, M; Sell, H	1
Aryal, S; Candeloro, P; Decuzzi, P; Di Mascolo, D; Guindani, M; Hsueh, WA; J Lyon, C; Ramirez, MR; Wang, J	1
Bravard, A; Disse, E; Laville, M; Rieusset, J; Tchernof, A; Veilleux, A; Vidal, H	1
Burcelin, R; Campbell, M; Camps, M; Decaunes, P; Domingo, P; Escoté, X; Fernández-Real, JM; Frühbeck, G; Galitzky, J; Giralt, M; Kolditz, CI; Langin, D; Laville, M; Luche, E; Michalski, MC; Mingrone, G; Moreno-Navarrete, JM; Ortega, F; Pardo, G; Ricart, W; Rodriguez-Hermosa, JI; Sabater, M; Salvador, J; Serino, M; Vendrell, J; Vidal, H; Vidal-Puig, A; Viguerie, N; Villarroya, F; Waget, A; Xifra, G; Zorzano, A	1
Burcelin, R; Fernández-Real, JM; Frühbeck, G; Luche, E; Mayas, D; Mingrone, G; Moreno-Navarrete, JM; Ortega, FJ; Ricart, W; Rodriguez-Hermosa, JI; Serino, M; Tinahones, FJ	1
Droog, S; Havekes, LM; Maas, AC; Offerman, EH; Pieterman, EJ; Princen, HM; van den Hoek, AM; van den Hoogen, RM; van der Hoorn, JW; van Nieuwkoop, A	1
Aragonès, G; Beltrán-Debón, R; Camps, J; García-Heredia, A; Geeraert, B; Holvoet, P; Joven, J; Pedro-Botet, J; Rodríguez-Gallego, E; Rull, A	1
Fan, N; Hou, Y; Liu, R; Peng, L; Peng, Y; Shen, W; Sun, H; Wang, Y; Xia, Z; Zhang, L	1
Sun, XD; Yu, YR	1
Cabay, RJ; Castellanos, KJ; Fantuzzi, G; Malecki, EA	1
Narasimhan, S; Weinstock, RS	1
Emmett, N; Leander, M; Li, L; Wang, G; Zhang, Y; Zhao, X	1
Alméras, N; Anand, SS; Dagenais, GR; Després, JP; Gerstein, HC; Hunt, DL; Jung, H; Punthakee, Z; Sharma, AM; Yusuf, S	1
Meierhofer, D; Sauer, S; Weidner, C	1
Ciaraldi, TP; Samad, F; Wang, J	1
Cao, Q; Chai, J; Guo, F; Ma, J; Zhang, M; Zhang, Y; Zhao, R; Zhao, W; Zhou, B	1
Chattipakorn, N; Chattipakorn, SC; Pipatpiboon, N; Sripetchwandee, J	1
Badgeley, MA; Bagalkot, V; Deiuliis, JA; Kampfrath, T; Maiseyeu, A; Rajagopalan, S	1
Beckett, E; Cardoso, RC; Chazenbalk, G; Dumesic, D; Keller, E; Madrigal, V; Moeller, J; Padmanabhan, V; Pease, A; Veiga-Lopez, A	1
Albu, J; Chiu, YL; Christos, P; Donovan, DS; Engelson, ES; Ginsberg, HN; Glesby, MJ; Ham, K; Hammad, H; Kotler, DP; Leung, V; Zhu, YS	1
Pugalendi, KV; Radhiga, T; Sundaresan, A	1
Farokhzad, OC; Langer, R; Xu, X; Xue, Y; Zhang, XQ	1
Guo, DF; Liu, X; Lu, KT; Mukohda, M; Rahmouni, K; Sigmund, CD; Stump, M	1
Gu, H; Hinds, TD; Khuder, SS; Lecka-Czernik, B; Najjar, SM; Qiu, B; Russo, L; Sanchez, ER; Stechschulte, LA; Warrier, M; Xu, Y; Yong, W; Zhang, M	1
Franczyk, MP; Imai, S; Kelly, SC; Moseley, AC; Qi, N; Stromsdorfer, KL; Yamaguchi, S; Yoon, MJ; Yoshino, J	1
Asuncion, F; Boyce, R; Chen, MM; Chinookoswong, N; Dwyer, D; Han, CY; Ke, HZ; Li, X; Liu, B; Niu, QT; Ominsky, MS; Stanislaus, S; Stolina, M; Véniant, MM; Villasenor, K; Wang, J; Wong, P; Xu, J	1
Kleemann, R; Kooistra, T; Liang, W; Morrison, MC; Mulder, P; van Bockel, JH; Verschuren, L; Wielinga, PY	1
Andreu, I; Buchwalder, C; Gray, SL; Häfeli, UO; Leung, D; Nicholson, KE; Saatchi, K; Schmitt, V; Tod, SE	1
Andres, A; Badger, TM; Blackburn, ML; Chen, JR; Frye, RE; Lazarenko, OP; Rose, S; Shankar, K	1
Soni, H	1
Guo, M; Lei, Y; Li, C; Lu, XY; Xu, S; Zhao, D	1
Frank, S; Goren, I; Pfeilschifter, J; Siebert, A	1
Brunt, JJ; Cai, EP; Krishnamurthy, M; Luk, CT; Schroer, SA; Shi, SY; Sivasubramaniyam, T; Winer, DA; Woo, M	1
Benson, KK; Briggs, ER; Chen, ER; Damle, M; Dispirito, JR; Dzeng, RK; Emmett, MJ; Foong, YH; Jolivert, JF; Kissig, M; Lazar, MA; Li, Z; Lim, HW; Medina, CJ; Mullican, SE; Peed, LC; Rajapurkar, SR; Seale, P; Soccio, RE; Steger, DJ; Won, KJ	1
Gottlieb, RA; Taylor, D	1
Burkart, A; Chawla, A; Chouinard, M; Corvera, S; Czech, MP; Konda, S; Lin, C; Nicoloro, SM; Perugini, RA; Puri, V; Ranjit, S; Straubhaar, J	1
Duval, C; Kersten, S; Keshtkar, S; Müller, M; Stienstra, R; van der Laak, J	1
Choi, JW; Kim, AY; Kim, JB; Kim, M; Lee, YS; Masuzaki, H; Park, KS; Son, HJ; Yasue, S	1
Huang, W; Huang, XZ; Yu, RM; Zhu, HL	1
Ecelbarger, CM; Liu, H; Ressom, HW; Song, J; Tiwari, S	1
Burkart, A; Chouinard, M; Corvera, S; Gealekman, O; Nicoloro, SM; Straubhaar, J	1
Chalasani, N; Vuppalanchi, R	1
Brunani, A; Castagna, G; Gondoni, LA; Graci, S; Liuzzi, A; Titon, A; Viberti, GC	1
Behar, A; Charnaux, N; Cohen-Boulakia, F; Cosson, E; Dabiré, H; Léger, G; Lestrade, R; Tarhzaoui, K; Valensi, P	1
Cohen, P	1
Ecelbarger, CM; Hu, J; Hu, X; Riazi, S; Tiwari, S; Wang, X	1
Arroyo, V; Clària, J; Dong, B; Ferré, N; González-Périz, A; Gronert, K; Horrillo, R; López-Parra, M; Martínez-Clemente, M; Morán-Salvador, E; Titos, E	1
Barbosa Aguila, M; de Souza Mendonca, L; Evangelista Carneiro, R; Fernandes-Santos, C; Mandarim-de-Lacerda, CA	1
Berger, JP; Berthiaume, M; Deshaies, Y; Festuccia, WT; Laplante, M; Thieringer, R	1
Cheon, HG; Choi, BH; Do, MS; Kim, YH	1
Rechler, MM; Zappalà, G	1
Gu, J; Li, C; Li, Y; Meng, D; Miao, Z; Wang, B; Wang, CY; Wang, J; Wang, L; Xing, X; Yan, S; Yuan, Y; Zhang, S	1
Annicotte, JS; Chavey, C; Clapé, C; Fajas, L; Guma, A; Hotamisligil, GS; Iankova, I; Jardin-Watelet, B; Lagarrigue, S; Langin, D; Lazennec, G; Mataki, C; Renard, E; Sanches, R; Schmidt, J; Stich, V; Strieter, R; Teyssier, J; Tuthill, A; Vidal-Puig, A; Vitkova, M; Yamamoto, H; Zorzano, A	1
Andres, J; Biedasek, K; Bobbert, T; Clemenz, M; Kintscher, U; Mai, K; Meinus, S; Möhlig, M; Pfeiffer, AF; Reinecke, F; Sabath, M; Spranger, J; Spuler, S; Weicht, J; Weickert, MO	1
Cai, B; Chen, L; Pan, Y; Wang, K; Wang, S; Xu, B; Yu, X; Zhou, S	1
Brûlé, S; Chewchuk, S; Houde, V; Lavigne, C; Liu, Y; Marette, A; Pilon, G; Sweeney, G; Xu, A	1
Ahmed, M; Edelmann, MJ; Karpe, F; Kessler, BM; Neville, MJ	1
Hong, JH; Hwang, EY; Jeong, YJ; Kim, HJ; Lee, IS	1
Cipriani, S; Fiorucci, S; Mencarelli, A; Palladino, G	1
Blüher, M; Catalán, V; Fernández-Real, JM; Frühbeck, G; Gómez-Ambrosi, J; Martínez-Barricarte, R; Moreno-Navarrete, JM; Ortega, FJ; Ricart, W; Rodríguez de Cordoba, S; Sabater, M	1
Bak, EJ; Cha, JH; Kim, JM; Park, HG; Yoo, YJ	1
Calmes, JM; Darimont, C; Gaillard, RC; Giusti, V; Leyvraz, C; Paroz, A; Pralong, FP; Suter, M; Verdumo, C	1
Bahia, LR; Bouskela, E; Domingues, RC; Geloneze, B; Godoy-Matos, AF; Kraemer-Aguiar, LG; Tambascia, M	1
Artis, DR; Bollag, G; Erbe, DV; Gareski, T; Gartrell, K; Harding, K; Ibrahim, PN; Jalenak, M; Kubasiak, D; Lin, JJ; Mansour, TS; Panza, D; Perreault, M; Saiah, E; Tobin, JF; Vlasuk, GP; Wang, S; Will, S; Womack, P	1
Bassaganya-Riera, J; Guri, AJ; Hontecillas, R	1
Benomar, Y; Bouchaert, E; Casteilla, L; Dacquet, C; Dumont, J; Guédin, A; Hennuyer, N; Ktorza, A; Langlois, A; Lefebvre, B; Lefebvre, P; Pattou, F; Pénicaud, L; Staels, B	1
Allen, K; Cali, AM; Caprio, S; Pierpont, BM; Savoye, M; Shaw, MM; Taksali, SE	1
Chaudhuri, A; Dandona, P; Ghanim, H	1
Döbrönte, R; Drimba, L; Németh, J; Pázmány, T; Peitl, B; Sári, R; Szilvássy, Z; Varga, A	1
Auwerx, J; Houtkooper, RH	1
Banks, AS; Blüher, M; Boström, P; Chalmers, MJ; Choi, JH; Estall, JL; Griffin, PR; Kajimura, S; Kamenecka, TM; Laznik, D; Ruas, JL; Spiegelman, BM	1
Bekiari, E; Kaloyianni, M; Koliakos, G; Paletas, K; Sarigianni, M; Topouridou, K; Tsapas, A	1
Chen, YT; Cheng, JT; Chi, TC; Lee, HH; Lo, SH; Yeh, CH	1
Clemenz, M; Foryst-Ludwig, A; Hartge, M; Hess, K; Kintscher, U; Marx, N; Sprang, C; Unger, T	1
Bu, SY; Chen, X; Guo, H; Hannaford, J; Jin, D; Mashek, DG; Zhang, Y	1
Al-Jebawi, AF	1
Liu, Q; Niu, YJ; Tao, RY; Tian, JY; Ye, F; Zhu, HB; Zhu, P	1
Almeida, RL; Almeida, TS; Fedrizzi, D; Fedrizzi, P	1
Kahn, BB; McGraw, TE	1
Baek, MC; Hwang, HH; Kim, JG; Lee, JE; Lee, W; Moon, PG; Ryu, SH	1
Rabøl, R	1
Bandyopadhyay, G; Fan, W; Gayen, JR; Li, P; Lu, M; Mahata, SK; Nalbandian, S; Olefsky, JM; Sarruf, DA; Schwartz, MW; Sharma, S; Talukdar, S; Webster, NJ	1
Choi, WS; Kim, IS; Kim, Y; Lee, JJ; Myung, CS; Zhang, WY	1
Li, D; Li, X; Li, Y; Ming, J; Shi, Y; Xie, Y; Zhang, N	1
Bastacky, S; Bilan, VP; Jones, HB; Mayers, RM; Poucher, SM; Salah, EM; Tofovic, SP; Zinker, B	1
Hu, W; Qiao, J	1
Llorens, S; Mendizábal, Y; Nava, E	1
Fernández-Real, JM; Moreno-Navarrete, JM; Ortega, F; Peral, B; Pérez-Pérez, R; Ricart, W; Sabater, M; Serrano, M; Tinahones, F	1
Banks, AS; Bruning, JB; Busby, SA; Cameron, MD; Chalmers, MJ; Choi, JH; Griffin, PR; He, Y; Jurczak, MJ; Kamenecka, TM; Kumar, N; Kuruvilla, DS; Laznik, D; Marciano, DP; Schürer, SC; Shin, Y; Shulman, GI; Spiegelman, BM; Vidović, D	1
Mohsen, IA	1
Gierman, LM; Huizinga, TW; Kleemann, R; Kloppenburg, M; Kooistra, T; Koudijs, A; Stojanovic-Susulic, V; Stoop, R; van der Ham, F; van Osch, GJ; Wielinga, PY; Zuurmond, AM	1
Bardova, K; Flachs, P; Illig, T; Janovska, P; Jilkova, ZM; Kopecky, J; Kuda, O; Kus, V; Rossmeisl, M; Svobodova, M; Wang-Sattler, R; Yu, Z	1
Guo, XH; Hui, Y; Yuan, GH; Zhang, WY	1
Ailhaud, G; Amri, EZ; Døskeland, SO; Jia, B; Kopperud, R; Kristiansen, K; Ma, T; Madsen, L; Petersen, RK; Techer, N; Wang, J	1
Balguy, I; Benelli, C; Cadoudal, T; Distel, E; Durant, S; Penot, G	1
Chambers, KT; Chen, Z; Colca, JR; Finck, BN; Hall, AM; Kletzien, RF; McDonald, WG; Mitra, MS; Qi, N; Vigueira, PA	1
Jang, JE; Jeon, MJ; Kim, EH; Kim, HS; Kim, M; Ko, MS; Koh, EH; Lee, CH; Lee, KU; Leem, J; Park, HS; Park, IS; Yoo, HJ	1
Brooks, VL; McCully, BH; Zhao, D	1
Adamski, J; Bardova, K; Bunschoten, A; Flachs, P; Hensler, M; Horakova, O; Illig, T; Janovska, P; Keijer, J; Kopecky, J; Kuda, O; Kus, V; Medrikova, D; Prehn, C; Rossmeisl, M; van Schothorst, EM; Wang-Sattler, R	1
Jang, JS; Jeong, JC; Kim, EJ; Lee, SJ; Park, UH; Sung, MR; Um, SJ; Youn, H	1
Bland, JS; Darland, G; Havekes, LM; Konda, V; Romijn, JA; Tripp, ML; van den Berg, SA; van Diepen, JA; van Dijk, KW; Voshol, PJ; Vroegrijk, IO	1
Bigley, AL; Jones, HB; Pemberton, J; Randall, KJ	1
Ensor, J; Esteva, FJ; Gonzalez-Angulo, AM; Green, MC; Hortobagyi, GN; Koenig, KB; Lee, MH; Moulder, SL; Murray, JL; Yeung, SC	1
Cherian-Shaw, M; Hammock, BD; Hye Khan, MA; Imig, JD; Nagasawa, T; Shaw, SM; Walsh, KA	1
Koc, M; Kovácová, Z; Kracmerová, J; Langin, D; Malisová, L; Rossmeislová, L; Siklová-Vítková, M; Stich, V; Tencerová, M; Viquerie, N	1
Berger, J; Dallas-Yang, Q; Doebber, T; Jiang, G; Li, Z; Liu, F; Moller, DE; Shen, X; Szalkowski, D; Wu, M; Zhang, BB; Zhou, G	1
Häring, HU; Stumvoll, M	1
Aleksunes, LM; Reagan, LA; Vergara, CM; Wang, F	1
Banday, AA; Hussain, T; Lokhandwala, MF; Umrani, DN	1
Belz, U; Herling, AW; Juretschke, HP; Kalisch, J; Kleinschmidt, E; Kramer, W; Kuhlmann, J; Neumann-Haefelin, C; Stein, M	1
Anglard, P; Bonnafous, S; Chavey, C; Mari, B; Monthouel, MN; Tartare-Deckert, S; Van Obberghen, E	1
Cobitz, AR; Haimbach, RE; Jucker, BM; Mayer, ME; Ohlstein, DH; Sarkar, SK; Schaeffer, TR; Smith, SA	1
Viberti, GC	1
Fischer, S; Hanefeld, M	1
Jones, NP; Jones, TA; Sautter, M; Van Gaal, LF	1
Birmingham, J; Buckingham, RE; Changani, KK; Hockings, PD; O'Brien, P; Osborne, J; Reid, DG; Saeed, N; Toseland, CN	1
Cawthorne, MA; Converset, V; Heller, M; Hochstrasser, DF; Nolan, A; Sanchez, JC; Schmid, G; Sennitt, MV; Wang, S	1
Kim, HS; Kim, MS; Koh, EH; Lee, KU; Park, HS; Park, JY; Youn, JH; Youn, JY	1
Chilton, RJ; Stolar, MW	1
Beck-Nielsen, H; Henriksen, JE; Hother-Nielsen, O; Poulsen, MK	1
Barnes, GT; Chen, H; Chou, CJ; Nichols, A; Ross, JS; Sole, J; Tan, G; Tartaglia, LA; Xu, H; Yang, D; Yang, Q	1
Marescaux, J; Rubino, F	1
Lokhandwala, M; Marwaha, A; Trivedi, M	1
Haslbeck, M; Jakob, S; Kellerer, M; Linn, T	1
Bains, RK; Fairhall, KM; Flavell, DM; Le Tissier, P; Robinson, IC; Strom, M; Wells, SE	1
Béréziat, V; Burnol, AF; Capitaine, N; Cariou, B; Girard, J; Kergoat, M; Laville, M; Le Marcis, V; Vega, N; Vidal, H	1
Akbay, E; Aktürk, M; Arslan, M; Ayvaz, G; Cakir, N; Elbeg, S; Karakoç, A; Sancak, B; Taneri, F; Törüner, F	1
Péterfy, M; Phan, J; Reue, K	1
Al-Haddad, W; Aljada, A; Dandona, P; Dhindsa, S; Ghanim, H; Hofmeyer, D; Mohanty, P; Syed, T; Tripathy, D	1
Bacon, BR; Brunt, EM; Neuschwander-Tetri, BA; Oliver, D; Wehmeier, KR	1
Febbraio, MA; Hawley, JA; Lau, W; Lessard, SJ; Lo Giudice, SL; Reid, JJ; Turner, N; Watt, MJ	1
Dufour, JF; Oneta, CM	1
Nagamani, M; Sepilian, V	1
Chouinard, M; Chui, PC; Corvera, S; Czech, MP; Lazar, MA; Leszyk, J; Nicoloro, S; Straubhaar, J; Wilson-Fritch, L	1
Füchtenbusch, M; Löbner, K	1
Brunani, A; Caumo, A; Graci, S; Liuzzi, A; Margarini, C; Viberti, GC	1
Banz, WJ; Davis, J; Iqbal, MJ; Peterson, R	1
Hanefeld, M	1
Arch, JR; Augstein, P; Cawthorne, MA; Demuth, HU; Heinke, P; Hoffmann, T; Meyer, A; Sennitt, MV; Stocker, C; Subramanian, A; Wargent, E	1
Chen, YY; Li, CM; Li, GW; Li, H; Liu, KL; Tang, YL; Wang, JP; Xing, XY; Yang, WY	1
Bonen, A; Coort, SL; Coumans, WA; Glatz, JF; Luiken, JJ; van der Vusse, GJ	1
Barkhem, T; Beno, DW; Cherrington, A; Edgerton, DS; Efendic, S; Fey, T; Fung, S; Goos-Nilsson, A; Grynfarb, M; Jacobson, PB; Kym, PR; Lane, BC; Link, JT; Marsh, K; Mika, A; Nga-Nguyen, B; Nguyen, PT; Ohman, L; Opgenorth, TJ; Osterland, M; Tu, N; von Geldern, TW; Wang, J; Wilcox, D; Zinker, B	1
Carvalheira, JB; Carvalho-Filho, MA; Curi, R; de Oliveira, MG; Hirabara, SM; Saad, MJ; Seabra, AB; Ueno, M; Velloso, LA	1
Lokhandwala, MF; Trivedi, M	1
Ecelbarger, CA; Hu, X; Khan, O; Riazi, S; Song, J; Wade, JB	1
Chetty, R; Coppack, S; Harte, A; Katz, J; Kumar, S; McTernan, P; Smith, S	1
Campbell, IW	1
James, AP; Mamo, JC; Watts, GF	1
Raskin, P; Strowig, SM	1
Aljada, A; Dandona, P; Dhindsa, S; Ghanim, H; Ravishankar, S; Sanalkumar, N; Tripathy, D	1
Moreno Sánchez, D	1
Cantürk, Z; Cetinarslan, B; Komsuoglu, B; Sahin, T; Tarkun, I; Türemen, E	1
Graham, TE; Kahn, BB; Kotani, K; Mody, N; Peroni, OD; Preitner, F; Quadro, L; Yang, Q; Zabolotny, JM	1
Abbasi, F; Chu, JW; Kim, SH; Lamendola, C; McLaughlin, TL; Polonsky, KS; Reaven, GM	1
Chen, ZP; Febbraio, MA; Hashem, M; Hawley, JA; Kemp, BE; Lessard, SJ; Reid, JJ; Watt, MJ	1
Déchêne, F; Dodin, S; Forest, JC; Lemay, A; Turcot, L	1
Andrew, R; Livingstone, DE; McInnes, KJ; Walker, BR	1
Kjølhede, P; Nystrom, FH; Sauma, L; Söderström, M; Stenkula, KG; Strålfors, P	1
Leiter, EH; Mistry, J; Pan, HJ; Reifsnyder, PC; Xiao, Q; Zhang, W	1
Bullock, M; Cook, C; Gaillard, T; Kaplow, J; Osei, K; Schuster, D	1
Ardecky, RJ; Boehm, MF; Broderick, CL; Carfagna, MA; Crombie, DL; D'Arrigo, J; Etgen, GJ; Faul, MM; Grese, TA; Havel, H; Hein, NI; Heyman, RA; Jolley, D; Klausing, K; Leibowitz, MD; Liu, S; Mais, DE; Mapes, CM; Marschke, KB; Michellys, PY; Montrose-Rafizadeh, C; Ogilvie, KM; Pascual, B; Reifel-Miller, A; Rungta, D; Tyhonas, JS; Urcan, MS; Wardlow, M; Yumibe, N	1
Hada, Y; Ito, Y; Kadowaki, T; Maki, T; Takekawa, S; Tsuchida, A; Yamauchi, T	1
Adler, S; Banz, WJ; Davis, J; Henry, N; Higginbotham, DA; Hou, Y; Meyers, CY; Oitker, J; Peterson, R; Steinle, JJ; Winters, TA	1
Biller, S; Cap, M; Chen, S; Cheng, PT; Chu, C; Devasthale, P; Farrelly, D; Fenderson, W; Gregg, R; Gu, L; Hariharan, N; Harrity, T; Jeon, Y; Kunselman, L; Mookhtiar, KA; Ponticiello, R; Qu, F; Ren, J; Ryono, D; Seethala, R; Shao, C; Tieman, A; Wang, W; Wetterau, J; Yang, WP; Zhang, H; Zhou, M	1
Blaak, EE; Hesselink, MK; Mensink, M; Moonen-Kornips, E; Russell, AP; Schaart, G; Schrauwen, P; Sels, JP	1
Arslan, M; Ayvaz, G; Bingöl, B; Biri, A; Cakir, N; Karakoç, A; Tiras, B; Törüner, F; Yilmaz, M	1
Rennings, AJ; Smits, P; Stewart, MW; Tack, CJ	1
Orchard, TJ	1
Esposito, K; Giugliano, D	1
Brandlhofer, S; Dorfmeister, B; Fürnsinn, C; Hagerty, BP; Hermann, M; Patsch, W; Schaap, FG; Stangl, H; Strobl, W	1
Andreelli, F; Beauloye, C; Bertrand, L; Foretz, M; Guigas, B; Horman, S; Taleux, N; Viollet, B	1
Houstis, N; Lander, ES; Rosen, ED	1
Aiello, LP; Clermont, A; Della Vecchia, K; King, GL; Kondo, T; Mastumoto, M; Rask-Madsen, C; Sotiropoulos, KB; Takahashi, J; Yasuda, Y	1
Aramori, I; Fujimura, T; Kimura, C; Mutoh, S; Oe, T; Sakuma, H; Takata, Y	1
Kurosaki, E; Maruyama, T; Nakano, R; Shibasaki, M; Shimaya, A; Yokono, M; Yoshida, S	1
Fried, SK; Goldberg, AP; Goldberg, NH; Gong, DW; Horenstein, RB; Hu, H; Hull, K; Lee, MJ; Nicklas, BJ; Pollin, TI; Ryan, AS; Shuldiner, AR; Snitker, S; Yang, RZ	1
Chen, YT; Li, PP; Liu, Q; Lu, XP; Ning, ZQ; Shan, S; Shen, ZF; Sun, SJ; Xie, MZ	1
Ecelbarger, CA; Hu, X; Khan, O; Riazi, S; Tiwari, S	1
Erbe, DV; Gartrell, K; Kirincich, SJ; Perreault, M; Suri, V; Tobin, JF; Wang, S; Will, S; Zhang, YL	1
Bagust, A; Beale, S; Hulme, L; Martin, A; Shearer, AT	1
Bagust, A; Goertz, A; Liebl, A; Schoeffski, O; Shearer, AT	1
Ampudia-Blasco, FJ; Bagust, A; Martínez-Lage Alvarez, B; París, G; Pérez Escolano, I; Shearer, AT	1
Aljada, A; Chaudhuri, A; Dandona, P; Dhindsa, S; Ghanim, H; Viswanathan, P	1
Bandyopadhyay, GK; Ofrecio, J; Olefsky, JM; Yu, JG	1
Ishida, Y; Ito, M; Kakutani, M; Matsushita, M; Nishiu, J; Shibata, T; Shindo, M	1
Bellot-Rojas, P; Caracas-Portilla, N; Cardoso-Saldaña, G; Jurado-Santacruz, F; Posadas-Romero, C; Posadas-Sanchez, R; Zamora-Gonzalez, J	1
Chow, WS; Hoo, RL; Kraegen, EW; Lam, KS; Sweeney, G; Tso, AW; Wang, Y; Wat, NM; Xu, A; Xu, JY; Zhang, J	1
Morin-Papunen, LC; Rautio, K; Ruokonen, A; Tapanainen, JS	1
Franck, N; Kjølhede, P; Nystrom, FH; Paulsson, JF; Sauma, L; Söderström, M; Strålfors, P; Westermark, GT	1
Hu, FB; van Dam, RM	1
Hesselink, MK; Mensink, M; Russell, AP; Schaart, G; Schrauwen, P; Sels, JP	1
Belury, MA; Liu, LF; Purushotham, A; Wendel, AA	1
Andrew, R; Homer, NZ; Karpe, F; Stimson, RH; Tan, GD; Wake, DJ; Walker, BR	1
Adler, S; Banz, W; Cho, KW; Davis, J; Higginbotham, A; Kim, YC; Moustaid-Moussa, N; O'Connor, T; Peterson, R; Shay, N; Tebbe, A	1
Hirosumi, J; Kawamura, I; Kimura, C; Manda, T; Minoura, H; Mutoh, S; Seki, J; Takakura, S; Takeshita, S	1
Brunani, A; Castagna, G; Caumo, A; Graci, S; Liuzzi, A; Viberti, G	1
Beaser, RS; Levy, P	1
Asano, S; Hansen, MK; Higashiyama, H; Mattie, MD; Okamoto, Y; Qiu, Y; Rong, JX; Ryan, TE; Strum, JC; Xie, M; Zhang, V; Zhu, L	1
Alevizos, M; Angelopoulou, N; Iliadis, F; Kadoglou, NP; Liapis, CD; Perrea, D	1
Bernante, P; Bianchi, K; Calcagno, A; Federspil, G; Milan, G; Pagano, C; Pilon, C; Rizzuto, R; Rossato, M; Urbanet, R; Vettor, R	1
Jeon, MJ; Kim, M; Kim, MS; Kim, SW; Kim, SY; Koh, EH; Lee, KU; Park, HS; Park, IS; Park, JY; Ryu, JW; Youn, JH	1
Henry, MJ; Nicholson, GC; Pasco, JA	1
Bohdanowicz-Pawlak, A; Jakubowska, J; Milewicz, A	1
Hart, CM; Holguin, F; Rojas, M	1
Chan, L; Chow, WS; Fong, CH; Hoo, RL; Lam, KS; Tam, S; Tse, HF; Tso, AW; Xu, A; Yau, MH	1
Comarow, A	1
Anhalt, H; Bhangoo, A; Collin, GB; Maclaren, N; Marshall, JD; Naggert, JK; Sinha, SK; Ten, S	1
Bahia, LR; Bottino, DA; Bouskela, E; Kraemer de Aguiar, LG; Nivoit, P; Villela, NR	1
Donaldson, J; Garcia-Puig, J; Hamann, A; Paul, G; Stewart, M	1
Best, JD; Fairley, KF; Farish, S; Kincaid-Smith, P; Proietto, J	1
Briscoe, CP; Buckingham, RE; Clapham, JC; Moore, GB; Pickavance, LC; Wilding, JP	1
Bennett, BD; Minge, CE; Norman, RJ; Robker, RL	1
Abram, SR; Carter, C; Dearman, J; Hester, RL; Xiang, L	1
Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Gravina, A; Maffioli, P; Piccinni, MN; Ragonesi, PD; Salvadeo, SA	1
Atabek, ME	1
Cong, WN; Liu, GT; Tao, RY; Tian, JY; Ye, F	1
Bellmann, K; Centeno-Baez, C; Dallaire, P; Deshaies, Y; Gélinas, S; Lamontagne, J; Laplante, M; Latour, MG; Marette, A; Penfornis, P; Peyot, ML; Prentki, M; Scherer, PE; Trujillo, ME	1
Benavides, S; Romo, A	1
Kadowaki, T; Kubota, N; Takasawa, K; Terauchi, Y	1
Kallen, CB; Lazar, MA	1
Boam, DS; Dickson, AJ; Sidaway, JE; Smith, SA	1
Bischoff, ED; Boehm, MF; Cesario, RM; Crombie, DL; Davies, PJ; Hamann, LG; Heyman, RA; Jow, L; Mondon, CE; Mukherjee, R; Nadzan, AM; Paterniti, JR	1
Akatsuka, H; Arakawa, K; Homma, K; Iijima, I; Inamasu, M; Kawanami, S; Matsumoto, M; Okumura, K; Ozeki, M; Saiga, Y; Watanabe, A; Yasuda, K	1
Al-Barazanji, KA; Bond, B; Buckingham, RE; Clapham, JC; Connor, SC; Slaughter, M; Toseland, CD; Turner, NC; West, A	1
Akanuma, Y; Ide, T; Kadowaki, T; Mochizuki, T; Murakami, K; Ohashi, M; Tobe, K; Yazaki, Y	1
Buckingham, RE; Chattington, PD; Walker, AB; Williams, G	1
Alexandersson, M; Bamberg, K; Bergström, M; Dahllöf, B; Edvardsson, U; Ljung, B	1
Auwerx, J; Rieusset, J; Vidal, H	1
Buckingham, RE; Pickavance, LC; Tadayyon, M; Widdowson, PS; Wilding, JP	1
Arch, JR; Buckingham, RE; Cai, XJ; Lister, CA; Pickavance, L; Wilding, J; Williams, G; Wilson, S	1
Chapman, H; Gould, GW; Lister, CA; Maier, VH; Melvin, DR; Murphy, GJ	1
Cawthorne, MA; Crombie, DL; Heyman, RA; Hislop, DC; Liu, YL; Sennitt, MV	1
Kenyon, CJ; Livingstone, DE; Walker, BR	1
Cawthorne, MA; Emilsson, V; Heyman, R; Liu, YL; O'Dowd, J; Sennitt, M; Wang, S	1
Daubresse, JC	1
Ahima, RS; Bailey, ST; Banerjee, RR; Bhat, S; Brown, EJ; Lazar, MA; Patel, HR; Steppan, CM; Wright, CM	1
Boehm, M; Crombie, DL; Davies, PJ; Depre, C; Heyman, RA; Leibowitz, MD; Liu, S; Nagy, L; Singh Ahuja, H; Tontonoz, P	1
Buckingham, RE; Finegood, DT; Kojwang, D; Leonard, T; McArthur, MD; Thomas, MJ; Topp, BG	1
Jacinto, SM; Ljung, B; Oakes, ND; Thalén, PG	1
Brown, KK; Görgün, CZ; Harrington, WW; Hotamisligil, GS; Kliewer, SA; Oliver, WR; Tong, Q; Uysal, KT; Way, JM; Willson, TM	1
Buckingham, RE; Pickavance, LC; Wilding, JP	1
Atzpodien, E; Bedoucha, M; Boelsterli, UA	1
Akanuma, Y; Ezaki, O; Fukayama, M; Hori, W; Ide, T; Itai, A; Kadowaki, T; Kagechika, H; Kamon, J; Kato, S; Kimura, S; Komeda, K; Kubota, N; Miki, H; Motojima, K; Murakami, K; Nagai, R; Shudo, K; Terauchi, Y; Tobe, K; Tsuboyama-Kasaoka, N; Tsuchida, A; Waki, H; Yamauchi, N; Yamauchi, T	1
Adler, A; Bush, E; Kramer, D; Rondinone, CM; Shapiro, R	1
Brunmair, B; Fürnsinn, C; Gras, F; Nowotny, P; Roden, M; Vierhapper, H; Waldhäusl, W	1
Buckingham, RE; Clarke, K; Cole, MA; Desrois, M; Draper, NJ; Sidell, RJ	1
Arner, P; Dicker, A; Hauner, H; Lönnqvist, F; Näslund, E; Rydén, M; van Harmelen, V	1
Chun, D; Cobitz, AR; Davis, HM; Haimbach, RE; Jucker, BM; Mayer, M; McIntosh, TS; Ohlstein, DH; Sarkar, SK; Schaeffer, TR; Smith, SA	1
Akarca, C; Barton, DM; Baskar, V; Buch, HN; Kamalakannan, D; Singh, BM	1
Anderson, JW; Frederich, RC; Konz, EC; Reynolds, LR	1

Reviews

21 review(s) available for rosiglitazone and Obesity

Article	Year
The PPARs: from orphan receptors to drug discovery. Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4 Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors	2000
The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease. Journal of medicinal chemistry, 2020, 05-28, Volume: 63, Issue:10 Topics: Animals; Anticholesteremic Agents; Drug Delivery Systems; Drug Development; Humans; Hypoglycemic Agents; Lipid Metabolism; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Obesity; PPAR gamma; Protein Structure, Tertiary	2020
Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA, 2022, 09-13, Volume: 328, Issue:10 Topics: Adolescent; Advisory Committees; Child; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Mass Screening; Metformin; Obesity; Prediabetic State; Preventive Health Services; Randomized Controlled Trials as Topic; Rosiglitazone	2022
Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management. Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:1 Topics: Bariatric Surgery; Biomarkers; Biopsy; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Dyslipidemias; Exercise; Fatty Liver; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Cirrhosis; Liver Diseases; Metabolic Syndrome; Metformin; Obesity; Oxidative Stress; Pioglitazone; Randomized Controlled Trials as Topic; Rosiglitazone; Thiazolidinediones; Weight Loss	2009
Mitochondrial function in skeletal muscle in type 2 diabetes. Danish medical bulletin, 2011, Volume: 58, Issue:4 Topics: Diabetes Mellitus, Type 2; Electron Transport; Humans; Hyperglycemia; Hypoglycemic Agents; Life Style; Mitochondria; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Oxidative Stress; Oxygen Consumption; Rosiglitazone; Saponins; Thiazolidinediones	2011
Glitazones: clinical effects and molecular mechanisms. Annals of medicine, 2002, Volume: 34, Issue:3 Topics: Adipose Tissue; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors	2002
Management of rosiglitazone-induced edema: two case reports and a review of the literature. Diabetes technology & therapeutics, 2002, Volume: 4, Issue:4 Topics: Body Weight; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diuresis; Edema; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Middle Aged; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones	2002
Rosiglitazone: potential beneficial impact on cardiovascular disease. International journal of clinical practice, 2003, Volume: 57, Issue:2 Topics: Albuminuria; Arteriosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hyperglycemia; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Insulin Resistance; Obesity; Risk Factors; Rosiglitazone; Thiazoles; Thiazolidinediones	2003
Addition of rosiglitazone to metformin is most effective in obese, insulin-resistant patients with type 2 diabetes. Diabetes, obesity & metabolism, 2003, Volume: 5, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Male; Metformin; Middle Aged; Obesity; Randomized Controlled Trials as Topic; Rosiglitazone; Thiazoles; Thiazolidinediones	2003
Type 2 diabetes, cardiovascular risk, and the link to insulin resistance. Clinical therapeutics, 2003, Volume: 25 Suppl B Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hemodynamics; Humans; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Obesity; Pioglitazone; Risk Factors; Rosiglitazone; Thiazolidinediones	2003
[Continuation 50. Type 2 diabetes: possibilities and limitations of pharmacological therapy]. MMW Fortschritte der Medizin, 2003, Dec-18, Volume: 145, Issue:51-52 Topics: 1-Deoxynojirimycin; Acarbose; Aged; Blood Glucose; Carbamates; Contraindications; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Fasting; Follow-Up Studies; Germany; Glucosamine; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemia; Hypoglycemic Agents; Imino Pyranoses; Insulin; Metformin; Middle Aged; Nateglinide; Obesity; Patient Compliance; Phenylalanine; Pioglitazone; Piperidines; Practice Guidelines as Topic; Risk Factors; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Time Factors	2003
[Alcoholic and non-alcoholic steatohepatitis]. Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:8 Topics: Alcoholism; Biopsy; Cholagogues and Choleretics; Diagnosis, Differential; Fatty Liver; Fatty Liver, Alcoholic; Gemfibrozil; Hepatitis; Hepatitis, Alcoholic; Humans; Hypolipidemic Agents; Insulin Resistance; Liver; Liver Transplantation; Middle Aged; Obesity; Pilot Projects; Randomized Controlled Trials as Topic; Rosiglitazone; Thiazolidinediones; Ultrasonography; Ursodeoxycholic Acid; Weight Loss	2004
[Inflammation and diabetes]. MMW Fortschritte der Medizin, 2004, Sep-02, Volume: 146, Issue:35-36 Topics: Adiponectin; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Blood Glucose; Body Weight; C-Reactive Protein; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exercise; Humans; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Inflammation; Inflammation Mediators; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Metabolic Syndrome; Obesity; Research; Risk Factors; Rosiglitazone; Thiazolidinediones	2004
[Glucose-independent impact of the glitazones on the cardiovascular outcome]. MMW Fortschritte der Medizin, 2005, Jan-13, Volume: 147, Issue:1-2 Topics: Body Mass Index; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Insulin Resistance; Longitudinal Studies; Middle Aged; Obesity; Pioglitazone; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Rosiglitazone; Thiazolidinediones	2005
The Clinical Significance of PPAR Gamma Agonism. Current molecular medicine, 2005, Volume: 5, Issue:3 Topics: Animals; Blood Glucose; Blood Pressure; Cardiovascular System; Coagulants; Cytokines; Diabetes Mellitus, Type 2; Female; Humans; Inflammation; Insulin Resistance; Islets of Langerhans; Male; Models, Biological; Models, Chemical; Obesity; Phenotype; Pioglitazone; PPAR gamma; Prognosis; Risk Factors; Rosiglitazone; Thiazolidinediones; Time Factors; Triglycerides	2005
[Medical management of primary nonalcoholic fatty liver disease]. Medicina clinica, 2005, Jun-18, Volume: 125, Issue:3 Topics: Anti-Obesity Agents; Anticholesteremic Agents; Atorvastatin; Chromans; Diabetes Mellitus, Type 2; Fatty Liver; Heptanoic Acids; Humans; Hypoglycemic Agents; Insulin Resistance; Lactones; Metabolic Syndrome; Metformin; Obesity; Orlistat; Prevalence; Pyrroles; Rosiglitazone; Thiazolidinediones; Troglitazone	2005
[Regulation of energy metabolism by AMPK: a novel therapeutic approach for the treatment of metabolic and cardiovascular diseases]. Medecine sciences : M/S, 2006, Volume: 22, Issue:4 Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adipogenesis; Allosteric Regulation; AMP-Activated Protein Kinases; Animals; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; Drug Design; Energy Intake; Energy Metabolism; Enzyme Activation; Fatty Acids; Glucose; Homeostasis; Humans; Hypothalamus; Lipogenesis; Mammals; Metformin; Models, Biological; Multienzyme Complexes; Myocardium; Obesity; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Subunits; Rosiglitazone; Thiazolidinediones	2006
Cost-effectiveness of rosiglitazone combination therapy for the treatment of type 2 diabetes mellitus in the UK. PharmacoEconomics, 2006, Volume: 24 Suppl 1 Topics: Combined Modality Therapy; Cost-Benefit Analysis; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Economics, Pharmaceutical; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Models, Economic; Obesity; Quality-Adjusted Life Years; Rosiglitazone; Thiazolidinediones; United Kingdom	2006
Cost-effectiveness of rosiglitazone oral combination for the treatment of type 2 diabetes in Germany. PharmacoEconomics, 2006, Volume: 24 Suppl 1 Topics: Administration, Oral; Adult; Aged; Cost-Benefit Analysis; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Economics, Pharmaceutical; Female; Germany; Glycated Hemoglobin; Hospitalization; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Models, Economic; Obesity; Quality-Adjusted Life Years; Rosiglitazone; Thiazolidinediones	2006
Lifetime health consequences and cost-effectiveness of rosiglitazone in combination with metformin for the treatment of type 2 diabetes in Spain. PharmacoEconomics, 2006, Volume: 24 Suppl 1 Topics: Adult; Cost-Benefit Analysis; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Economics, Pharmaceutical; Female; Hospitalization; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Obesity; Quality-Adjusted Life Years; Rosiglitazone; Spain; Thiazolidinediones	2006
[The importance of syndrome X in daily practice]. Revue medicale de Bruxelles, 2000, Volume: 21, Issue:6 Topics: Anthropometry; Cardiovascular Diseases; Diet, Reducing; Exercise; Humans; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Lipoproteins, HDL; Lipoproteins, LDL; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones	2000

Trials

33 trial(s) available for rosiglitazone and Obesity

Article	Year
Comparing the individual effects of metformin and rosiglitazone and their combination in obese women with polycystic ovary syndrome: a randomized controlled trial. Fertility and sterility, 2020, Volume: 113, Issue:1 Topics: Adult; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Rosiglitazone; Treatment Outcome; Waist Circumference; Young Adult	2020
Youth-onset type 2 diabetes mellitus: lessons learned from the TODAY study. Mayo Clinic proceedings, 2014, Volume: 89, Issue:6 Topics: Adolescent; Blood Glucose; Child; Combined Modality Therapy; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Obesity; Risk Reduction Behavior; Rosiglitazone; Thiazolidinediones; Treatment Outcome	2014
Impact of rosiglitazone on body composition, hepatic fat, fatty acids, adipokines and glucose in persons with impaired fasting glucose or impaired glucose tolerance: a sub-study of the DREAM trial. Diabetic medicine : a journal of the British Diabetic Association, 2014, Volume: 31, Issue:9 Topics: Absorptiometry, Photon; Adipokines; Adult; Blood Glucose; Body Composition; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Acids, Nonesterified; Female; Glucose; Humans; Intra-Abdominal Fat; Liver; Male; Obesity; Rosiglitazone; Thiazolidinediones; Tomography, X-Ray Computed; Treatment Outcome	2014
Tissue factor expression in obese type 2 diabetic subjects and its regulation by antidiabetic agents. Journal of obesity, 2015, Volume: 2015 Topics: Adult; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Gene Expression Regulation; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones; Thromboplastin	2015
Effect of Recombinant Human Growth Hormone and Rosiglitazone for HIV-Associated Abdominal Fat Accumulation on Adiponectin and other Markers of Inflammation. HIV clinical trials, 2016, Volume: 17, Issue:2 Topics: Abdominal Fat; Adiponectin; Adult; Aged; Biomarkers; Blood Glucose; C-Reactive Protein; Drug Therapy, Combination; Female; HIV Infections; Human Growth Hormone; Humans; Hypoglycemic Agents; Interleukin-6; Male; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones; Young Adult	2016
[Effects of rosiglitazone on inflammatory reaction and insulin resistance in obese patients with newly diagnosed type 2 diabetes]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008, Volume: 28, Issue:6 Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Inflammation; Insulin Resistance; Interleukin-1beta; Interleukin-6; Male; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha	2008
Rosiglitazone improves glucose metabolism in obese adolescents with impaired glucose tolerance: a pilot study. Obesity (Silver Spring, Md.), 2011, Volume: 19, Issue:1 Topics: Adolescent; Body Composition; Body Weight; Double-Blind Method; Female; Glucose; Glucose Intolerance; Humans; Hypoglycemic Agents; Male; Obesity; Patient Compliance; Pilot Projects; Placebos; Rosiglitazone; Thiazolidinediones; Treatment Outcome	2011
Effects of metformin and rosiglitazone on peripheral insulin resistance and β-cell function in obesity: a double-blind, randomized, controlled study. The Journal of international medical research, 2011, Volume: 39, Issue:2 Topics: Administration, Oral; Adult; Anthropometry; Asian People; Body Composition; China; Diabetes Mellitus, Type 2; Double-Blind Method; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Metformin; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones; Young Adult	2011
A randomized controlled trial of the effect of rosiglitazone and clomiphene citrate versus clomiphene citrate alone in overweight/obese women with polycystic ovary syndrome. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:4 Topics: Adult; Blood Glucose; Clomiphene; Drug Therapy, Combination; Female; Fertility Agents, Female; Humans; Hypoglycemic Agents; Infertility, Female; Insulin; Insulin Resistance; Obesity; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Young Adult	2012
[Investigation of amylin level changes among obese patients at different glucose metabolic states and effects of rosiglitazone intervention]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2011, Dec-18, Volume: 43, Issue:6 Topics: Adult; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones	2011
Phase I trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor-positive metastatic breast cancer. Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:1 Topics: Administration, Oral; Aged; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Metformin; Middle Aged; Obesity; Overweight; Postmenopause; Rosiglitazone; Thiazolidinediones; Time Factors	2013
The combined effect of triple therapy with rosiglitazone, metformin, and insulin aspart in type 2 diabetic patients. Diabetes care, 2003, Volume: 26, Issue:12 Topics: Aged; Blood Glucose; Blood Pressure; C-Peptide; Circadian Rhythm; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucose Clamp Technique; Glycated Hemoglobin; Glycolysis; Humans; Hypoglycemic Agents; Insulin; Insulin Aspart; Male; Metformin; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones	2003
Evidence for a potent antiinflammatory effect of rosiglitazone. The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:6 Topics: Adult; Aged; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Chemokine CCL2; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; I-kappa B Proteins; Insulin; Insulin Resistance; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Male; Middle Aged; NF-kappa B; Obesity; Rosiglitazone; Solubility; Thiazolidinediones; Transcription Factor RelA; Tumor Necrosis Factor-alpha	2004
Nonalcoholic steatohepatitis: histologic features and clinical correlations with 30 blinded biopsy specimens. Human pathology, 2004, Volume: 35, Issue:9 Topics: Biopsy; Blood Glucose; Fatty Liver; Female; Fibrosis; Humans; Hypoglycemic Agents; Insulin Resistance; Liver; Liver Function Tests; Male; Middle Aged; Obesity; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Tomography, X-Ray Computed; Transcription Factors	2004
[Anti-hypertensive effect of rosiglitazone in non-diabetic essential hypertension]. Zhonghua nei ke za zhi, 2004, Volume: 43, Issue:12 Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Female; Humans; Hypertension; Insulin Resistance; Male; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones	2004
The effect of metformin and rosiglitazone on postprandial lipid metabolism in obese insulin-resistant subjects. Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:4 Topics: Adult; Apolipoproteins B; Biomarkers; Blood Glucose; Fatty Acids, Nonesterified; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Lipids; Male; Metformin; Middle Aged; Obesity; Postprandial Period; Rosiglitazone; Thiazolidinediones; Triglycerides	2005
The effect of rosiglitazone on overweight subjects with type 1 diabetes. Diabetes care, 2005, Volume: 28, Issue:7 Topics: Adult; Blood Glucose; Body Mass Index; Body Size; C-Peptide; Diabetes Mellitus, Type 1; Double-Blind Method; Ethnicity; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Obesity; Placebos; Rosiglitazone; Thiazolidinediones; Weight Gain	2005
Effect of rosiglitazone on insulin resistance, C-reactive protein and endothelial function in non-obese young women with polycystic ovary syndrome. European journal of endocrinology, 2005, Volume: 153, Issue:1 Topics: Adult; Biomarkers; Body Weight; C-Reactive Protein; Endothelium, Vascular; Female; Hormones; Humans; Hypoglycemic Agents; Insulin Resistance; Muscle, Smooth, Vascular; Obesity; Polycystic Ovary Syndrome; Rosiglitazone; Thiazolidinediones; Vasculitis	2005
Rosiglitazone and ethinyl estradiol/cyproterone acetate as single and combined treatment of overweight women with polycystic ovary syndrome and insulin resistance. Human reproduction (Oxford, England), 2006, Volume: 21, Issue:1 Topics: Adolescent; Adult; Androgens; Blood Glucose; Cholesterol, HDL; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Hirsutism; Humans; Insulin; Insulin Resistance; Middle Aged; Obesity; Polycystic Ovary Syndrome; Rosiglitazone; Thiazolidinediones	2006
Discrepancies in the regulation of plasma adiponectin and TNF-alpha levels and adipose tissue gene expression in obese African Americans with glucose intolerance: a pilot study using rosiglitazone. Ethnicity & disease, 2005,Autumn, Volume: 15, Issue:4 Topics: Adiponectin; Adipose Tissue; Adult; Black or African American; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Gene Expression; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Longitudinal Studies; Male; Middle Aged; Obesity; Pilot Projects; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha	2005
Fluid retention and vascular effects of rosiglitazone in obese, insulin-resistant, nondiabetic subjects. Diabetes care, 2006, Volume: 29, Issue:3 Topics: Adult; Blood Pressure; Capillary Permeability; Edema; Female; Forearm; Humans; Insulin; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Obesity; omega-N-Methylarginine; Plasma Volume; Regional Blood Flow; Rosiglitazone; Thiazolidinediones; Vasodilation	2006
Comparison of metformin versus rosiglitazone in patients with Acanthosis nigricans: a pilot study. Journal of drugs in dermatology : JDD, 2006, Volume: 5, Issue:9 Topics: Acanthosis Nigricans; Administration, Oral; Adult; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Obesity; Pilot Projects; Rosiglitazone; Thiazolidinediones; Treatment Outcome	2006
Rosiglitazone treatment alleviates inflammation and improves liver function in overweight women with polycystic ovary syndrome: a randomized placebo-controlled study. Fertility and sterility, 2007, Volume: 87, Issue:1 Topics: Adolescent; Adult; Female; Humans; Hypoglycemic Agents; Inflammation; Liver Diseases; Obesity; Polycystic Ovary Syndrome; Rosiglitazone; Thiazolidinediones; Treatment Outcome	2007
Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus. International journal of obesity (2005), 2007, Volume: 31, Issue:8 Topics: Biopsy; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Gene Expression Regulation; Heat-Shock Proteins; Humans; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Skeletal; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR-beta; Rosiglitazone; Thiazolidinediones; Transcription Factors	2007
Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men. The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:5 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adult; Aged; Cortisone; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Fenofibrate; Gas Chromatography-Mass Spectrometry; Hormone Antagonists; Humans; Hydrocortisone; Hypolipidemic Agents; Insulin Resistance; Kinetics; Liver; Male; Metyrapone; Microdialysis; Middle Aged; Mifepristone; Obesity; PPAR alpha; PPAR gamma; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones	2007
Rosiglitazone is more effective than metformin in improving fasting indexes of glucose metabolism in severely obese, non-diabetic patients. Diabetes, obesity & metabolism, 2008, Volume: 10, Issue:6 Topics: Adipose Tissue; Adolescent; Adult; Aged; B-Lymphocytes; Blood Glucose; Body Composition; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Male; Metformin; Middle Aged; Obesity; Obesity, Morbid; Rosiglitazone; Thiazolidinediones; Weight Loss	2008
Beneficial effects of combined treatment with rosiglitazone and exercise on cardiovascular risk factors in patients with type 2 diabetes. Diabetes care, 2007, Volume: 30, Issue:9 Topics: Aged; Cardiovascular Diseases; Combined Modality Therapy; Diabetes Mellitus, Type 2; Exercise Therapy; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Obesity; Risk Factors; Rosiglitazone; Thiazolidinediones	2007
[The effect of rosiglitazone on plasma adiponectin and resistin levels in obese PCO woman--preliminary report]. Przeglad lekarski, 2007, Volume: 64, Issue:2 Topics: Adiponectin; Adolescent; Adult; Body Mass Index; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Middle Aged; Obesity; Polycystic Ovary Syndrome; Resistin; Rosiglitazone; Thiazolidinediones; Triglycerides	2007
Adiponectin mediates the suppressive effect of rosiglitazone on plasminogen activator inhibitor-1 production. Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:12 Topics: 3T3-L1 Cells; Adenoviridae; Adipocytes; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Fibrinolytic Agents; Genetic Vectors; Humans; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Plasminogen Activator Inhibitor 1; PPAR gamma; Recombinant Proteins; RNA, Messenger; Rosiglitazone; Serpin E2; Serpins; Sulfonylurea Compounds; Thiazolidinediones; Transduction, Genetic; Treatment Outcome	2007
Comparison of fixed-dose rosiglitazone/metformin combination therapy with sulphonylurea plus metformin in overweight individuals with Type 2 diabetes inadequately controlled on metformin alone. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2008, Volume: 116, Issue:1 Topics: Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Lipids; Male; Metformin; Obesity; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones	2008
Reduction of proteinuria by rosiglitazone in non-diabetic renal disease. Nephrology (Carlton, Vic.), 2008, Volume: 13, Issue:1 Topics: Adult; Aged; Biomarkers; Blood Glucose; Body Mass Index; Cross-Over Studies; Diabetes Mellitus; Disease Progression; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Obesity; PPAR gamma; Proteinuria; Retrospective Studies; Rosiglitazone; Thiazolidinediones; Treatment Outcome	2008
Rosiglitazone therapy improves insulin resistance parameters in overweight and obese diabetic patients intolerant to metformin. Archives of medical research, 2008, Volume: 39, Issue:4 Topics: Adiponectin; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Italy; Leptin; Male; Metformin; Middle Aged; Obesity; Overweight; Resistin; Rosiglitazone; Single-Blind Method; Thiazolidinediones; Tumor Necrosis Factor-alpha	2008
Rosiglitazone amplifies the benefits of lifestyle intervention measures in long-standing type 2 diabetes mellitus. Diabetes, obesity & metabolism, 2002, Volume: 4, Issue:4 Topics: Biomarkers; Blood Pressure; Body Constitution; Body Mass Index; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Life Style; Obesity; Placebos; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides; Weight Loss	2002

Other Studies

234 other study(ies) available for rosiglitazone and Obesity

Article	Year
Discovery of novel dual functional agent as PPARgamma agonist and 11beta-HSD1 inhibitor for the treatment of diabetes. Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Body Weight; Diabetes Mellitus, Experimental; Fats; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Mice; Models, Molecular; Obesity; Phenylpropionates; PPAR gamma; Rats; Rats, Wistar	2009
Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents. Journal of medicinal chemistry, 2011, Feb-10, Volume: 54, Issue:3 Topics: Administration, Oral; Animals; Binding, Competitive; Biological Availability; Crystallography, X-Ray; Diabetes Mellitus; Dogs; ERRalpha Estrogen-Related Receptor; Ethers; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Ligands; Macaca fascicularis; Male; Mice; Mice, Knockout; Models, Molecular; Molecular Structure; Obesity; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Structure-Activity Relationship; Thiazolidinediones; Triglycerides	2011
Synthesis and biological evaluation of 5-benzylidenepyrimidine-2,4,6(1H,3H,5H)-trione derivatives for the treatment of obesity-related nonalcoholic fatty liver disease. Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22 Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Alanine Transaminase; Animals; Barbiturates; Body Weight; Cholesterol; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Female; Glucose; Glucose Tolerance Test; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Leptin; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Piperidines; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tissue Distribution; Triglycerides	2012
Macrophage membrane-camouflaged lipoprotein nanoparticles for effective obesity treatment based on a sustainable self-reinforcement strategy. Acta biomaterialia, 2022, 10-15, Volume: 152 Topics: Animals; Cyclic Nucleotide Phosphodiesterases, Type 5; Hypoglycemic Agents; Lipoproteins; Lipoproteins, HDL; Macrophages; Mice; Mice, Inbred C57BL; Mice, Obese; Nanoparticles; Obesity; Peroxisome Proliferator-Activated Receptors; Rosiglitazone; Sildenafil Citrate; Treatment Outcome	2022
Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibility. Molecular metabolism, 2022, Volume: 66 Topics: Adipocytes, Beige; Chromatin; Cyclic AMP; Humans; Obesity; PPAR gamma; Rosiglitazone; Thermogenesis; Transcriptome	2022
miR-223 Plays a Key Role in Obesogen-Enhanced Adipogenesis in Mesenchymal Stem Cells and in Transgenerational Obesity. Endocrinology, 2023, 03-13, Volume: 164, Issue:5 Topics: Adipogenesis; Animals; Cell Differentiation; Female; Male; Mesenchymal Stem Cells; Mice; MicroRNAs; Obesity; PPAR gamma; Pregnancy; Rosiglitazone	2023
Effects of Fatty Acid Metabolites on Adipocytes Britening: Role of Thromboxane A2. Cells, 2023, 01-30, Volume: 12, Issue:3 Topics: Adipocytes, Brown; Fatty Acids; Humans; Obesity; Prostaglandins I; Rosiglitazone; Thromboxane A2	2023
Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice. Biochimica et biophysica acta. Molecular basis of disease, 2024, Volume: 1870, Issue:1 Topics: Animals; Caloric Restriction; Diabetes Mellitus, Type 2; Ethanolamine; Ethanolamines; Female; Mice; Niclosamide; Non-alcoholic Fatty Liver Disease; Obesity; Rosiglitazone	2024
Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity. Biochemical pharmacology, 2020, Volume: 171 Topics: 3T3-L1 Cells; Adipogenesis; Adiposity; Animals; Anti-Inflammatory Agents; Cells, Cultured; Diet, High-Fat; Dronabinol; Fatty Liver; HEK293 Cells; Humans; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Rosiglitazone	2020
Metformin, rosiglitazone, or both for obese women with polycystic ovary syndrome? Fertility and sterility, 2020, Volume: 113, Issue:1 Topics: Female; Humans; Hypoglycemic Agents; Metformin; Obesity; Polycystic Ovary Syndrome; Rosiglitazone	2020
Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling. Molecular metabolism, 2020, Volume: 42 Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Cell Differentiation; Diet, High-Fat; Humans; Insulin; Insulin Resistance; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; PPAR gamma; Rosiglitazone; Signal Transduction; Smad Proteins; Transforming Growth Factor beta	2020
A novel dual-targeted rosiglitazone-loaded nanoparticle for the prevention of diet-induced obesity via the browning of white adipose tissue. Journal of controlled release : official journal of the Controlled Release Society, 2021, 01-10, Volume: 329 Topics: Adipose Tissue, White; Animals; Diet; Diet, High-Fat; Energy Metabolism; Mice; Mice, Inbred C57BL; Nanoparticles; Obesity; Rosiglitazone	2021
Photoacoustic molecular imaging-escorted adipose photodynamic-browning synergy for fighting obesity with virus-like complexes. Nature nanotechnology, 2021, Volume: 16, Issue:4 Topics: Adipose Tissue, White; Animals; Hepatitis B; Humans; Indoles; Mice; Molecular Imaging; Obesity; Organometallic Compounds; Photoacoustic Techniques; Rosiglitazone; Viral Core Proteins	2021
Combined treatment with FABP4 inhibitor ameliorates rosiglitazone-induced liver steatosis in obese diabetic db/db mice. Basic & clinical pharmacology & toxicology, 2021, Volume: 129, Issue:3 Topics: Animals; Diabetes Mellitus, Type 2; Drug Combinations; Fatty Acid-Binding Proteins; Fatty Liver; Hepatocytes; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Models, Animal; Obesity; Primary Cell Culture; Rosiglitazone; Triglycerides	2021
Rosiglitazone Requires Hepatocyte PPARγ Expression to Promote Steatosis in Male Mice With Diet-Induced Obesity. Endocrinology, 2021, 11-01, Volume: 162, Issue:11 Topics: Animals; Diet, High-Fat; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; PPAR gamma; Rosiglitazone	2021
Caffeic acid and hydroxytyrosol have anti-obesogenic properties in zebrafish and rainbow trout models. PloS one, 2017, Volume: 12, Issue:6 Topics: Animals; Anti-Obesity Agents; Caffeic Acids; Models, Biological; Obesity; Oncorhynchus mykiss; Phenylethyl Alcohol; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones; Zebrafish	2017
Rosiglitazone Improves Insulin Resistance Mediated by 10,12 Conjugated Linoleic Acid in a Male Mouse Model of Metabolic Syndrome. Endocrinology, 2017, 09-01, Volume: 158, Issue:9 Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Body Weight; Disease Models, Animal; Glucose; Insulin Resistance; Linoleic Acids, Conjugated; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Receptors, LDL; Rosiglitazone; Thiazolidinediones	2017
Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment. ACS nano, 2017, 09-26, Volume: 11, Issue:9 Topics: Adipocytes, White; Adipose Tissue, White; Animals; Anti-Obesity Agents; Drug Delivery Systems; Hypoglycemic Agents; Male; Mice, Inbred C57BL; Obesity; Rosiglitazone; Transdermal Patch	2017
Rosiglitazone is superior to resveratrol in inducing the expression of glyceroneogenic genes in adipose tissue from obese participants. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2018, Volume: 43, Issue:3 Topics: Adipose Tissue; Adult; Female; Gene Expression Regulation; Humans; Male; Middle Aged; Obesity; Pregnancy; Resveratrol; Rosiglitazone; Stilbenes; Thiazolidinediones; Tissue Culture Techniques	2018
Identification and expression patterns of adipokine genes during adipocyte differentiation in the Tibetan goat (Capra hircus). Gene, 2018, Feb-15, Volume: 643 Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adipokines; Adipose Tissue; Animals; Apelin; Cell Differentiation; Female; Fibroblast Growth Factors; Goats; Lipid Metabolism; Mice; Nicotinamide Phosphoribosyltransferase; Obesity; Resistin; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones	2018
Role of peroxisome proliferator-activated receptor-gamma activation on visfatin, advanced glycation end products, and renal oxidative stress in obesity-induced type 2 diabetes mellitus. Human & experimental toxicology, 2018, Volume: 37, Issue:11 Topics: Animals; Antioxidants; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Hypoglycemic Agents; Insulin; Kidney; Lipid Peroxidation; Nicotinamide Phosphoribosyltransferase; Obesity; Oxidative Stress; PPAR gamma; Rats, Wistar; Rosiglitazone; Signal Transduction; Streptozocin	2018
PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. The Journal of clinical investigation, 2018, 06-01, Volume: 128, Issue:6 Topics: Acetylation; Adipose Tissue, White; Animals; Body Weight; Energy Metabolism; Female; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Transgenic; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones	2018
Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes. Biochimica et biophysica acta. Molecular and cell biology of lipids, 2018, Volume: 1863, Issue:7 Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adipose Tissue, Brown; Animals; Cell Differentiation; Lactic Acid; Lipid Droplets; Mice; Obesity; Palmitates; Phenotype; Pioglitazone; PPAR gamma; Rosiglitazone	2018
An Hsp20-FBXO4 Axis Regulates Adipocyte Function through Modulating PPARγ Ubiquitination. Cell reports, 2018, 06-19, Volume: 23, Issue:12 Topics: Adipocytes; Adipose Tissue, White; Adiposity; Animals; Cold Temperature; Energy Metabolism; F-Box Proteins; Glucose; HSP20 Heat-Shock Proteins; Inflammation; Insulin Resistance; Lipid Metabolism; Mice, Inbred C57BL; Mice, Knockout; Obesity; PPAR gamma; Protein Stability; RNA, Messenger; Rosiglitazone; Ubiquitination	2018
PPARγ Deficiency Suppresses the Release of IL-1β and IL-1α in Macrophages via a Type 1 IFN-Dependent Mechanism. Journal of immunology (Baltimore, Md. : 1950), 2018, 10-01, Volume: 201, Issue:7 Topics: Animals; Cells, Cultured; Inflammasomes; Inflammation; Interferon Type I; Interleukin-1alpha; Interleukin-1beta; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Obesity; PPAR gamma; Rosiglitazone; Sequence Analysis, RNA	2018
Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis. Redox biology, 2019, Volume: 22 Topics: Adipose Tissue; Animals; Biomarkers; Blood Glucose; Body Weight; Diet, High-Fat; Disease Models, Animal; Glucose Intolerance; Hepatocytes; Lipid Metabolism; Male; Mice; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Obesity; Oleic Acids; Protective Agents; Rosiglitazone; Triglycerides	2019
In vivo multi-tissue efficacy of peroxisome proliferator-activated receptor-γ therapy on glucose and fatty acid metabolism in obese type 2 diabetic rats. Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:12 Topics: Adipose Tissue, Brown; Animals; Diabetes Mellitus, Type 2; Glucose; Hypoglycemic Agents; Insulin; Lipid Metabolism; Liver; Muscle, Skeletal; Obesity; PPAR gamma; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones	2013
Oral green tea catechins transiently lower plasma glucose concentrations in female db/db mice. Journal of medicinal food, 2013, Volume: 16, Issue:4 Topics: Adiponectin; Adipose Tissue; Animals; Anti-Inflammatory Agents; Blood Glucose; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Flavonoids; Hyperglycemia; Hypoglycemic Agents; Inflammation; Intercellular Adhesion Molecule-1; Mice; Mice, Knockout; Mice, Obese; Obesity; Phytotherapy; Plant Extracts; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha; Weight Gain	2013
6-gingerol inhibits rosiglitazone-induced adipogenesis in 3T3-L1 adipocytes. Phytotherapy research : PTR, 2014, Volume: 28, Issue:2 Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Catechols; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Down-Regulation; Fatty Acid Synthases; Fatty Acid-Binding Proteins; Fatty Alcohols; Mice; Obesity; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Triglycerides	2014
Protein sets define disease states and predict in vivo effects of drug treatment. Molecular & cellular proteomics : MCP, 2013, Volume: 12, Issue:7 Topics: Adipose Tissue, White; Animals; Diet, High-Fat; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred C57BL; Myocardium; Obesity; PPAR gamma; Protein Processing, Post-Translational; Proteomics; Rosiglitazone; Salicylates; Thiazolidinediones	2013
PPAR agonist-induced reduction of Mcp1 in atherosclerotic plaques of obese, insulin-resistant mice depends on adiponectin-induced Irak3 expression. PloS one, 2013, Volume: 8, Issue:4 Topics: Adipocytes; Adiponectin; Animals; Chemokine CCL2; Diet, High-Fat; Fenofibrate; Inflammation; Insulin; Insulin Resistance; Interleukin-1 Receptor-Associated Kinases; Leptin; Macrophages; Mice; Mice, Inbred C57BL; Obesity; Peroxisome Proliferator-Activated Receptors; Plaque, Atherosclerotic; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones	2013
Adipose tissue-related proteins locally associated with resolution of inflammation in obese mice. International journal of obesity (2005), 2014, Volume: 38, Issue:2 Topics: Adipocytes; Adipokines; Adipose Tissue, White; Animals; Diet, High-Fat; Dietary Fats; Docosahexaenoic Acids; Energy Metabolism; Enzyme-Linked Immunosorbent Assay; Fatty Acids, Omega-3; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Real-Time Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones	2014
Rosiglitazone-loaded nanospheres for modulating macrophage-specific inflammation in obesity. Journal of controlled release : official journal of the Controlled Release Society, 2013, Sep-28, Volume: 170, Issue:3 Topics: Adipose Tissue, White; Animals; Anti-Inflammatory Agents; Bone Marrow Cells; Cell Line; Cells, Cultured; Gene Expression Regulation; Hepatitis; Hypoglycemic Agents; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nanospheres; Obesity; Polyvinyl Alcohol; Receptors, LDL; Rosiglitazone; Thiazolidinediones	2013
The expression of FTO in human adipose tissue is influenced by fat depot, adiposity, and insulin sensitivity. Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:6 Topics: 3T3-L1 Cells; Adipogenesis; Adipose Tissue; Adiposity; Adult; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Body Mass Index; Cell Differentiation; Diabetes Mellitus, Type 2; Female; Gene Expression; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Middle Aged; Obesity; Omentum; PPAR gamma; Proteins; RNA, Messenger; Rosiglitazone; Thiazolidinediones	2013
A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction. Diabetologia, 2013, Volume: 56, Issue:11 Topics: Acute-Phase Proteins; Adipocytes; Adipose Tissue; Adult; Animals; Carrier Proteins; Humans; In Vitro Techniques; Inflammation; Insulin Resistance; Lipopolysaccharides; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha	2013
Inflammation and insulin resistance exert dual effects on adipose tissue tumor protein 53 expression. International journal of obesity (2005), 2014, Volume: 38, Issue:5 Topics: Adipocytes; Adipogenesis; Adipose Tissue; Analysis of Variance; Animals; Bariatric Surgery; Diet, High-Fat; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Genes, p53; Humans; Inflammation; Insulin Resistance; Male; Metformin; Mice; Mice, Knockout; Obesity; Omentum; Rosiglitazone; Thiazolidinediones	2014
APOE3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome. Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:6* Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Apolipoprotein E3; Atorvastatin; Cholesterol Ester Transfer Proteins; Disease Models, Animal; Fenofibrate; Glucagon-Like Peptide 1; Heptanoic Acids; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Liraglutide; Male; Metabolic Syndrome; Mice, Transgenic; Niacin; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Rosiglitazone; Thiazolidinediones	2014
Rosiglitazone and fenofibrate exacerbate liver steatosis in a mouse model of obesity and hyperlipidemia. A transcriptomic and metabolomic study. Journal of proteome research, 2014, Mar-07, Volume: 13, Issue:3 Topics: Animals; Disease Models, Animal; Fatty Liver; Fenofibrate; Gene Expression Profiling; Gene Expression Regulation; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Metabolome; Mice; Mice, Transgenic; Obesity; Peroxisome Proliferator-Activated Receptors; Protein Interaction Mapping; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcriptome	2014
Midkine, a potential link between obesity and insulin resistance. PloS one, 2014, Volume: 9, Issue:2 Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Cytokines; Female; Glucose Transporter Type 4; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Middle Aged; Midkine; Obesity; Phosphorylation; Rosiglitazone; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Thiazolidinediones; Tumor Necrosis Factor-alpha	2014
[The protective effects of rosiglitazone on kidney in diet-induced obese rats]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2014, Volume: 45, Issue:1 Topics: Animals; Body Weight; Diet, High-Fat; Fatty Acids, Nonesterified; Intra-Abdominal Fat; Kidney Glomerulus; Nitric Oxide; Obesity; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Triglycerides; Vascular Endothelial Growth Factor A; Vasodilation	2014
Therapeutic administration of orlistat, rosiglitazone, or the chemokine receptor antagonist RS102895 fails to improve the severity of acute pancreatitis in obese mice. Pancreas, 2014, Volume: 43, Issue:6 Topics: Acute Disease; Animals; Anti-Obesity Agents; Benzoxazines; Interleukin-12; Interleukin-18; Lactones; Male; Mice, Inbred C57BL; Obesity; Orlistat; Pancreatitis; Piperidines; Receptors, CCR2; Rosiglitazone; Severity of Illness Index; Thiazolidinediones; Treatment Failure; Vasodilator Agents	2014
Altered expression profile of renal α(1D)-adrenergic receptor in diabetes and its modulation by PPAR agonists. Journal of diabetes research, 2014, Volume: 2014 Topics: Animals; Cell Dedifferentiation; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fenofibrate; Gene Expression Profiling; Hypoglycemic Agents; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Obesity; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR gamma; Rats; Rats, Zucker; Receptors, Adrenergic, alpha-1; Rosiglitazone; Thiazolidinediones; Up-Regulation	2014
Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs. Journal of proteome research, 2014, Dec-05, Volume: 13, Issue:12 Topics: Adipose Tissue, White; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Gene Expression Profiling; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Metabolic Networks and Pathways; Metabolomics; Mice, Inbred C57BL; Obesity; Proteomics; Rosiglitazone; Tandem Mass Spectrometry; Thiazolidinediones; Transcriptome	2014
The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation. PloS one, 2015, Volume: 10, Issue:7 Topics: 3T3-L1 Cells; Adenosine; Adipocytes; Adipogenesis; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Biomarkers; Cell Differentiation; DNA Methylation; DNA Modification Methylases; Gene Expression Profiling; Hypoglycemic Agents; Mice; Obesity; PPAR gamma; Proteins; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones	2015
Effects of PPARγ agonist on heart rate variability and cardiac mitochondrial function in obese-insulin resistant rats. International journal of cardiology, 2015, Dec-15, Volume: 201 Topics: Animals; Heart Rate; Insulin Resistance; Male; Mitochondria, Heart; Obesity; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Treatment Outcome	2015
Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals. Journal of controlled release : official journal of the Controlled Release Society, 2015, Nov-10, Volume: 217 Topics: Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Cell Line; Cholesterol; Cytokines; Fluorescein-5-isothiocyanate; Gadolinium; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Nanoparticles; Obesity; Paclitaxel; Phagocytosis; Phosphatidylethanolamines; Phosphatidylserines; Phospholipases A2; Polyethylene Glycols; Polystyrenes; Rosiglitazone; Tamoxifen; Thiazolidinediones	2015
Developmental Programming: Impact of Gestational Steroid and Metabolic Milieus on Adiposity and Insulin Sensitivity in Prenatal Testosterone-Treated Female Sheep. Endocrinology, 2016, Volume: 157, Issue:2 Topics: Adiposity; Animals; Disease Models, Animal; Embryonic Development; Female; Flutamide; Insulin Resistance; Obesity; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Rosiglitazone; Sheep; Testosterone; Thiazolidinediones	2016
Ursolic acid and rosiglitazone combination improves insulin sensitivity by increasing the skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat diet-fed C57BL/6J mice. Journal of physiology and biochemistry, 2016, Volume: 72, Issue:2 Topics: Animals; Anti-Obesity Agents; Antioxidants; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Therapy, Combination; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Rosiglitazone; Second Messenger Systems; Thiazolidinediones; Triterpenes; Ursolic Acid; Weight Gain	2016
Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles. Proceedings of the National Academy of Sciences of the United States of America, 2016, May-17, Volume: 113, Issue:20 Topics: 16,16-Dimethylprostaglandin E2; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Carbohydrate Metabolism; Diet; Drug Delivery Systems; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Nanomedicine; Nanoparticles; Neovascularization, Physiologic; Obesity; Rosiglitazone; Thiazolidinediones	2016
Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance. Physiological genomics, 2016, 07-01, Volume: 48, Issue:7 Topics: 3T3 Cells; Adipogenesis; Animals; Body Weight; Brain; Cell Line; Diet, High-Fat; Energy Metabolism; Female; HEK293 Cells; Homeostasis; Humans; Leptin; Male; Mice; Neurons; Obesity; PPAR gamma; Pro-Opiomelanocortin; Rosiglitazone; Thiazolidinediones; Weight Gain	2016
FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPARγ Agonist Rosiglitazone. Endocrinology, 2016, Volume: 157, Issue:10 Topics: Adiposity; Animals; Energy Metabolism; Fatty Liver; Glucose Intolerance; Intra-Abdominal Fat; Lipid Metabolism; Lipids; Male; Mice, Knockout; Obesity; PPAR gamma; Rosiglitazone; Tacrolimus Binding Proteins; Thiazolidinediones; Weight Gain	2016
NAMPT-Mediated NAD(+) Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice. Cell reports, 2016, 08-16, Volume: 16, Issue:7 Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Cyclin-Dependent Kinase 5; Cytokines; Fatty Acids, Nonesterified; Female; Gene Expression Regulation; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Mice; Mice, Knockout; Muscle, Skeletal; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Obesity; Phosphorylation; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones	2016
FGF21 Is Not a Major Mediator for Bone Homeostasis or Metabolic Actions of PPARα and PPARγ Agonists. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2017, Volume: 32, Issue:4 Topics: Animals; Bone Density; Dietary Fats; Fibroblast Growth Factors; Gene Expression Regulation; Glucose; Homeostasis; Humans; Insulin; Male; Mice; Mice, Knockout; Obesity; Osteoprotegerin; PPAR alpha; PPAR gamma; RANK Ligand; Rosiglitazone; Thiazolidinediones	2017
Reduction of obesity-associated white adipose tissue inflammation by rosiglitazone is associated with reduced non-alcoholic fatty liver disease in LDLr-deficient mice. Scientific reports, 2016, 08-22, Volume: 6 Topics: Adipose Tissue, White; Animals; Inflammation; Male; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, LDL; Rosiglitazone; Thiazolidinediones	2016
Characterization of alendronic- and undecylenic acid coated magnetic nanoparticles for the targeted delivery of rosiglitazone to subcutaneous adipose tissue. Nanomedicine : nanotechnology, biology, and medicine, 2017, Volume: 13, Issue:2 Topics: Adipose Tissue; Animals; Hypoglycemic Agents; Magnetite Nanoparticles; Mice; Mice, Inbred C57BL; Obesity; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones; Tissue Distribution; Undecylenic Acids	2017
Maternal Obesity Programs Senescence Signaling and Glucose Metabolism in Osteo-Progenitors From Rat and Human. Endocrinology, 2016, Volume: 157, Issue:11 Topics: Adipogenesis; Animals; Cell Proliferation; Cells, Cultured; Cellular Senescence; Female; Glucose; Humans; Insulin Resistance; Male; Mesenchymal Stem Cells; Obesity; Osteogenesis; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Skull; Thiazolidinediones; Thinness	2016
Peptide-based GLP-1/glucagon co-agonists: A double-edged sword to combat diabesity. Medical hypotheses, 2016, Volume: 95 Topics: Animals; Clinical Trials as Topic; Diabetes Complications; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Glucagon-Like Peptide-1 Receptor; Humans; Mice; Mice, Obese; Obesity; Oxyntomodulin; Peptides; Rats; Receptors, Glucagon; Recombinant Proteins; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Venoms	2016
Role of the adipose PPARγ-adiponectin axis in susceptibility to stress and depression/anxiety-related behaviors. Molecular psychiatry, 2017, Volume: 22, Issue:7 Topics: Adipocytes; Adiponectin; Adipose Tissue; Adiposity; Animals; Anxiety; Blood-Brain Barrier; Depression; Female; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; RNA, Messenger; Rosiglitazone; Stress, Psychological; Thiazolidinediones	2017
Anti-Inflammatory Effects of Rosiglitazone in Obesity-Impaired Wound Healing Depend on Adipocyte Differentiation. PloS one, 2016, Volume: 11, Issue:12 Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Inflammatory Agents; Cell Differentiation; Chemokine CXCL2; Cyclooxygenase 2; Fatty Acid-Binding Proteins; Female; Kruppel-Like Transcription Factors; Mice; Mice, Obese; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Wound Healing	2016
FAK signalling controls insulin sensitivity through regulation of adipocyte survival. Nature communications, 2017, 02-06, Volume: 8 Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Adiposity; Adult; Animals; Apoptosis; Cell Survival; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Female; Focal Adhesion Kinase 1; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Middle Aged; Obesity; PPAR gamma; Primary Cell Culture; Rosiglitazone; Signal Transduction; Thiazolidinediones	2017
Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice. The Journal of clinical investigation, 2017, Apr-03, Volume: 127, Issue:4 Topics: Animals; Diet, High-Fat; Epigenesis, Genetic; Hypoglycemic Agents; Intra-Abdominal Fat; Male; Mice, 129 Strain; Mice, Inbred C57BL; Obesity; PPAR gamma; Protein Binding; Regulatory Elements, Transcriptional; Rosiglitazone; Subcutaneous Fat, Abdominal; Thiazolidinediones; Transcriptional Activation; Transcriptome; Uncoupling Protein 1	2017
Parkin-mediated mitophagy is downregulated in browning of white adipose tissue. Obesity (Silver Spring, Md.), 2017, Volume: 25, Issue:4 Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Dioxoles; Down-Regulation; Energy Metabolism; Hypoglycemic Agents; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitophagy; Obesity; Rosiglitazone; Thiazolidinediones; Ubiquitin-Protein Ligases; Uncoupling Protein 1	2017
Cidea is associated with lipid droplets and insulin sensitivity in humans. Proceedings of the National Academy of Sciences of the United States of America, 2008, Jun-03, Volume: 105, Issue:22 Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Amino Acid Sequence; Animals; Apoptosis Regulatory Proteins; Body Mass Index; Carrier Proteins; Humans; Insulin Resistance; Lipolysis; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Obesity; Perilipin-1; Phosphoproteins; PPAR gamma; Proteins; RNA Interference; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Triglycerides	2008
Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue. The Journal of biological chemistry, 2008, Aug-15, Volume: 283, Issue:33 Topics: 3T3 Cells; Adipose Tissue; Animals; Cell Line; Diet, Fat-Restricted; Dietary Fats; Inflammation; Liver; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred Strains; Obesity; PPAR gamma; RNA; Rosiglitazone; Thiazolidinediones; Triglycerides	2008
Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress. Molecular endocrinology (Baltimore, Md.), 2008, Volume: 22, Issue:9 Topics: 3T3-L1 Cells; Acetylcysteine; Adipose Tissue; Animals; Antioxidants; Base Sequence; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Humans; Hypoxia; Kidney; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Oxidative Stress; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha	2008
Chronic rosiglitazone therapy normalizes expression of ACE1, SCD1 and other genes in the kidney of obese Zucker rats as determined by microarray analysis. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2008, Volume: 116, Issue:6 Topics: Animals; Chromosome Mapping; Gene Expression Regulation, Enzymologic; Genome; Kidney; Male; Obesity; Oligonucleotide Array Sequence Analysis; Peptidyl-Dipeptidase A; Rats; Rats, Zucker; Rosiglitazone; Stearoyl-CoA Desaturase; Thiazolidinediones	2008
Enhanced angiogenesis in obesity and in response to PPARgamma activators through adipocyte VEGF and ANGPTL4 production. American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:5 Topics: Adipocytes, White; Adipose Tissue, White; Angiopoietin-Like Protein 4; Angiopoietins; Animals; Antigens, CD; Cadherins; Capillaries; Cells, Cultured; Culture Media, Conditioned; Epididymis; Gene Expression; Humans; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Neovascularization, Physiologic; Obesity; Pioglitazone; PPAR gamma; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor B	2008
Evaluation of rosiglitazone administration on cardiovascular function in severe obesity. Clinical cardiology, 2008, Volume: 31, Issue:12 Topics: Adult; Blood Pressure; Body Weight; Cardiovascular System; Diastole; Echocardiography, Doppler; Female; Humans; Insulin; Insulin Resistance; Male; Obesity; PPAR gamma; Rosiglitazone; Systole; Thiazolidinediones; Ventricular Function, Left	2008
Capillary endothelial but not lymphatic function is restored under rosiglitazone in Zucker diabetic fatty rats. Microvascular research, 2009, Volume: 77, Issue:2 Topics: Albumins; Animals; Capillaries; Capillary Permeability; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium; Lymphatic System; Male; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factor A	2009
Rosiglitazone increases testosterone in hypogonadal type 2 diabetic men. Diabetes & vascular disease research, 2009, Volume: 6, Issue:1 Topics: Adult; Aged; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Hypogonadism; Male; Obesity; Rosiglitazone; Testosterone; Thiazolidinediones; Vasodilator Agents	2009
Regulation of angiotensin II type I receptor (AT1R) protein levels in the obese Zucker rat kidney and urine. Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Hypoglycemic Agents; Kidney; Metabolic Syndrome; Obesity; PPAR gamma; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Rosiglitazone; Sodium Chloride, Dietary; Tetrazoles; Thiazolidinediones; Thinness	2009
Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:6 Topics: Adiponectin; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Chemokine CCL2; Diet; Dietary Fats; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Liver; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Obese; Muscle, Skeletal; Obesity; PPAR gamma; Resistin; Rosiglitazone; Thiazolidinediones	2009
Rosiglitazone aggravates nonalcoholic Fatty pancreatic disease in C57BL/6 mice fed high-fat and high-sucrose diet. Pancreas, 2009, Volume: 38, Issue:3 Topics: Adipose Tissue; Animals; Bezafibrate; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Sucrose; Energy Metabolism; Fenofibrate; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Obesity; Pancreatic Diseases; PPAR alpha; PPAR-beta; Rosiglitazone; Thiazolidinediones; Weight Gain	2009
Additive action of 11beta-HSD1 inhibition and PPAR-gamma agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats. International journal of obesity (2005), 2009, Volume: 33, Issue:5 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiponectin; Animals; Disease Models, Animal; Fatty Liver; Male; Obesity; PPAR gamma; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Rosiglitazone; Thiazolidinediones; Triazoles; Triglycerides	2009
B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation. Experimental & molecular medicine, 2009, Mar-31, Volume: 41, Issue:3 Topics: Adipocytes; Adipokines; Animals; B-Cell Activating Factor; B-Cell Activation Factor Receptor; Cell Differentiation; Hypoglycemic Agents; Inflammation; Mice; Obesity; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha	2009
IGFBP-3, hypoxia and TNF-alpha inhibit adiponectin transcription. Biochemical and biophysical research communications, 2009, May-15, Volume: 382, Issue:4 Topics: 3T3-L1 Cells; Adiponectin; Animals; Cell Hypoxia; Cobalt; Fibroblasts; Genes, Reporter; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 3; Mice; Obesity; PPAR gamma; Retinoid X Receptor alpha; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Tumor Necrosis Factor-alpha	2009
Insulin resistance acts as an independent risk factor exacerbating high-purine diet induced renal injury and knee joint gouty lesions. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2009, Volume: 58, Issue:10 Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Gout; Homeostasis; Hyperuricemia; Hypoglycemic Agents; Insulin Resistance; Knee Joint; Male; Obesity; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Purines; Rats; Rats, Inbred OLETF; Risk Factors; Rosiglitazone; Thiazolidinediones; Uric Acid	2009
CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance. Cell metabolism, 2009, Volume: 9, Issue:4 Topics: Adipose Tissue; Animals; Chemokine CXCL5; Gene Expression Regulation; Humans; Insulin Resistance; Macrophages; Mice; Obesity; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazolidinediones; Tumor Necrosis Factor-alpha	2009
Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21. Diabetes, 2009, Volume: 58, Issue:7 Topics: Cell Line; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Fibroblast Growth Factors; Gene Expression Regulation; Glucose Clamp Technique; Glycerol; Homeostasis; Humans; Hyperinsulinism; Hypoglycemic Agents; Lecithins; Male; Obesity; PPAR alpha; PPAR gamma; Reference Values; RNA, Messenger; Rosiglitazone; Thiazolidinediones	2009
Neferine enhances insulin sensitivity in insulin resistant rats. Journal of ethnopharmacology, 2009, Jul-06, Volume: 124, Issue:1 Topics: Animals; Anti-Obesity Agents; Benzylisoquinolines; Blood Glucose; Female; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Resistance; Nelumbo; Obesity; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Rosiglitazone; Seeds; Thiazolidinediones; Triglycerides; Tumor Necrosis Factor-alpha	2009
Functional significance of skeletal muscle adiponectin production, changes in animal models of obesity and diabetes, and regulation by rosiglitazone treatment. American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:3 Topics: Adiponectin; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Obese; Muscle, Skeletal; Obesity; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones	2009
Proteomic analysis of human adipose tissue after rosiglitazone treatment shows coordinated changes to promote glucose uptake. Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:1 Topics: Adipose Tissue; Adult; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Galectin 1; Gene Expression; Glucose; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Image Processing, Computer-Assisted; Insulin; Male; Mass Spectrometry; Middle Aged; Obesity; Proteome; Proteomics; Regression Analysis; RNA Processing, Post-Transcriptional; RNA, Messenger; Rosiglitazone; Thiazolidinediones	2010
Artemisia capillaris inhibits lipid accumulation in 3T3-L1 adipocytes and obesity in C57BL/6J mice fed a high fat diet. Journal of medicinal food, 2009, Volume: 12, Issue:4 Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Artemisia; Carnitine O-Palmitoyltransferase; Cell Line; Diet; Dietary Fats; Disease Models, Animal; Fatty Acids, Nonesterified; Flavonoids; Glycerolphosphate Dehydrogenase; Hypolipidemic Agents; Leptin; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Obesity; Phenols; Phytotherapy; Plant Extracts; PPAR gamma; Rosiglitazone; Thiazolidinediones; Triglycerides	2009
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats. Journal of lipid research, 2010, Volume: 51, Issue:4 Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Male; Muscle, Skeletal; Obesity; Phosphorylation; Random Allocation; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors	2010
Complement factor H is expressed in adipose tissue in association with insulin resistance. Diabetes, 2010, Volume: 59, Issue:1 Topics: Adipose Tissue; Complement Factor B; Complement Factor H; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Obesity; Omentum; Organ Specificity; Reference Values; Rosiglitazone; Skin; Thiazolidinediones; Weight Loss; White People	2010
Inhibitory effect of evodiamine alone and in combination with rosiglitazone on in vitro adipocyte differentiation and in vivo obesity related to diabetes. International journal of obesity (2005), 2010, Volume: 34, Issue:2 Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Cell Differentiation; Cell Line; Dietary Fats; Drug Therapy, Combination; Hypoglycemic Agents; Insulin; Liver; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Quinazolines; Rosiglitazone; Thiazolidinediones; Weight Gain	2010
Selective effects of PPARgamma agonists and antagonists on human pre-adipocyte differentiation. Diabetes, obesity & metabolism, 2010, Volume: 12, Issue:3 Topics: Adipocytes; Adult; Anilides; Cell Differentiation; Cell Line; Cells, Cultured; Female; Gene Expression; Humans; Obesity; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones	2010
Rosiglitazone decreases intra- to extramyocellular fat ratio in obese non-diabetic adults with metabolic syndrome. Diabetic medicine : a journal of the British Diabetic Association, 2010, Volume: 27, Issue:1 Topics: Adipose Tissue; Adult; Body Mass Index; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Magnetic Resonance Spectroscopy; Male; Metabolic Syndrome; Obesity; Rosiglitazone; Thiazolidinediones; Triglycerides; Waist-Hip Ratio	2010
Modulation of nutrient sensing nuclear hormone receptors promotes weight loss through appetite suppression in mice. Diabetes, obesity & metabolism, 2010, Volume: 12, Issue:3 Topics: Animals; Appetite Depressants; Appetite Regulation; Energy Metabolism; Insulin Resistance; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; PPAR alpha; PPAR delta; PPAR gamma; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Loss	2010
Abscisic acid synergizes with rosiglitazone to improve glucose tolerance and down-modulate macrophage accumulation in adipose tissue: possible action of the cAMP/PKA/PPAR γ axis. Clinical nutrition (Edinburgh, Scotland), 2010, Volume: 29, Issue:5 Topics: Abscisic Acid; Adipose Tissue; Animals; Blood Glucose; Cyclic AMP-Dependent Protein Kinases; Data Collection; Diabetes Mellitus; Glucose Intolerance; Inflammation; Insulin; Macrophages; Mice; Mice, Obese; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones	2010
Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans. The Journal of clinical investigation, 2010, Volume: 120, Issue:5 Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Gene Expression Regulation; Humans; Insulin Resistance; Male; Mice; Mice, Obese; Obesity; PPAR gamma; Proteasome Endopeptidase Complex; Retinoid X Receptor alpha; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Ubiquitin Thiolesterase	2010
Rosiglitazone, thiazolidinediones and atherosclerosis. Atherosclerosis, 2010, Volume: 211, Issue:2 Topics: Anti-Inflammatory Agents; Atherosclerosis; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Inflammation; Insulin Resistance; Leukocytes, Mononuclear; Nitric Oxide; Obesity; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones; Time Factors	2010
Involvement of cholecystokinin in baseline and post-prandial whole body insulin sensitivity in rats. European journal of pharmacology, 2010, Oct-10, Volume: 644, Issue:1-3 Topics: Animals; Cholecystokinin; Gene Expression Regulation; Glucose Clamp Technique; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Obesity; Polymerase Chain Reaction; Postprandial Period; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Rosiglitazone; Thiazolidinediones	2010
Obesity: New life for antidiabetic drugs. Nature, 2010, Jul-22, Volume: 466, Issue:7305 Topics: Adipose Tissue; Animals; Cyclin-Dependent Kinase 5; Diabetes Mellitus, Experimental; Dietary Fats; Humans; Insulin; Ligands; Mice; Obesity; Phosphorylation; PPAR gamma; Rosiglitazone; Thiazolidinediones	2010
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature, 2010, Jul-22, Volume: 466, Issue:7305 Topics: Adipose Tissue; Amino Acid Sequence; Animals; Cell Line; Cyclin-Dependent Kinase 5; Diabetes Mellitus, Experimental; Dietary Fats; Humans; Insulin; Ligands; Mice; Models, Molecular; Obesity; Phosphorylation; Phosphoserine; PPAR gamma; Protein Conformation; Rosiglitazone; Thiazolidinediones	2010
Effect of glucose and insulin on oxidized low-density lipoprotein phagocytosis by human monocytes: a pilot study. Angiology, 2011, Volume: 62, Issue:2 Topics: Adolescent; Adult; Body Mass Index; Case-Control Studies; Cell Culture Techniques; Female; Glucose; Guanidines; Humans; Hypoglycemic Agents; Insulin; Lipoproteins, LDL; Male; Monocytes; Obesity; Phagocytosis; Pilot Projects; Rosiglitazone; Sulfones; Sweetening Agents; Thiazolidinediones; Young Adult	2011
Effects of metformin on rosiglitazone-induced cardiac hypertrophy in mice. Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:9 Topics: Animals; Body Weight; Cardiomegaly; Drug Therapy, Combination; Eating; Male; Metformin; Mice; Mice, Inbred BALB C; Obesity; Rosiglitazone; Thiazolidinediones; Weight Gain	2010
PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice. Cardiovascular diabetology, 2010, Oct-18, Volume: 9 Topics: Abdominal Fat; Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Benzimidazoles; Benzoates; CD3 Complex; Chemokine CXCL12; Chemotaxis; Dietary Fats; Disease Models, Animal; Inflammation; Insulin Resistance; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Rosiglitazone; T-Lymphocytes; Telmisartan; Thiazolidinediones; Time Factors	2010
Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-gamma activation and function in lipid homeostasis and energy expenditure. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:2 Topics: Acute-Phase Proteins; Adipocytes; Adipose Tissue, Brown; Animals; Dietary Fats; Energy Metabolism; Homeostasis; Hypoglycemic Agents; Lipid Metabolism; Lipocalin-2; Lipocalins; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Oncogene Proteins; PPAR gamma; Rosiglitazone; Thiazolidinediones	2011
Remission of diabetes mellitus type 2 with severe hyperglycemia after Exenatide treatment. Diabetes research and clinical practice, 2010, Volume: 90, Issue:3 Topics: Diabetes Mellitus, Type 2; Exenatide; Female; Humans; Metformin; Middle Aged; Obesity; Peptides; Remission Induction; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Venoms; Weight Loss	2010
Improvement on lipid metabolic disorder by 3'-deoxyadenosine in high-fat-diet-induced fatty mice. The American journal of Chinese medicine, 2010, Volume: 38, Issue:6 Topics: Animals; Area Under Curve; Cordyceps; Deoxyadenosines; Dietary Fats; Disease Models, Animal; Fenofibrate; Glucose; Glucose Clamp Technique; Glucose Intolerance; Insulin; Insulin Resistance; Lipid Metabolism; Lipid Metabolism Disorders; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Phytotherapy; Rosiglitazone; Thiazolidinediones; Weight Gain	2010
Severe HDL-c reduction during rosiglitazone therapy in an obese woman with type 2 diabetes. Arquivos brasileiros de endocrinologia e metabologia, 2010, Volume: 54, Issue:7 Topics: Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones	2010
Rosiglitazone, PPARγ, and type 2 diabetes. The New England journal of medicine, 2010, Dec-30, Volume: 363, Issue:27 Topics: Cyclin-Dependent Kinase 5; Diabetes Mellitus, Type 2; Gene Expression; Hypoglycemic Agents; Obesity; Phosphorylation; PPAR gamma; Rosiglitazone; Thiazolidinediones	2010
Identification of the target proteins of rosiglitazone in 3T3-L1 adipocytes through proteomic analysis of cytosolic and secreted proteins. Molecules and cells, 2011, Volume: 31, Issue:3 Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Cytoplasm; Cytoskeletal Proteins; Diabetes Mellitus, Type 2; Eukaryotic Translation Initiation Factor 5A; Fatty Acid-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Insulin; Mice; Obesity; Peptide Initiation Factors; Proteome; RNA-Binding Proteins; Rosiglitazone; Tandem Mass Spectrometry; Thiazolidinediones	2011
Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nature medicine, 2011, Volume: 17, Issue:5 Topics: Aged; Animals; Brain; Diabetes Mellitus, Type 2; Energy Metabolism; Humans; Hypoglycemic Agents; Insulin Resistance; Mice; Mice, Knockout; Middle Aged; Obesity; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones; Weight Gain	2011
Synergistic improvement in insulin resistance with a combination of fenofibrate and rosiglitazone in obese type 2 diabetic mice. Archives of pharmacal research, 2011, Volume: 34, Issue:4 Topics: Animals; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy, Combination; Fenofibrate; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Rosiglitazone; Thiazolidinediones	2011
Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. The Journal of endocrinology, 2011, Volume: 210, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Diabetic Nephropathies; Disease Models, Animal; Enalapril; Humans; Hypoglycemic Agents; Kidney; Liver; Male; Metabolic Syndrome; Myocardium; Obesity; PPAR gamma; Rats; Rosiglitazone; Thiazolidinediones	2011
Expression and regulation of adipocyte fatty acid binding protein in granulosa cells and its relation with clinical characteristics of polycystic ovary syndrome. Endocrine, 2011, Volume: 40, Issue:2 Topics: Adult; Body Mass Index; C-Reactive Protein; Cells, Cultured; Fatty Acid-Binding Proteins; Female; Gene Expression Regulation; Granulosa Cells; Humans; Hypercholesterolemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Obesity; Polycystic Ovary Syndrome; PPAR gamma; RNA, Messenger; Rosiglitazone; Severity of Illness Index; Testosterone; Thiazolidinediones; Up-Regulation	2011
Reactivity of the aorta and mesenteric resistance arteries from the obese spontaneously hypertensive rat: effects of glitazones. American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:4 Topics: Animals; Aorta; Blood Pressure; Endothelium, Vascular; Hypoglycemic Agents; In Vitro Techniques; Male; Mesenteric Arteries; Microcirculation; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Obesity; Pioglitazone; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rosiglitazone; Superoxides; Thiazolidinediones; Vascular Resistance; Vasoconstrictor Agents	2011
Decreased STAMP2 expression in association with visceral adipose tissue dysfunction. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:11 Topics: Adipocytes; Adult; Aged; Cell Differentiation; Diabetes Mellitus, Type 2; Female; Gene Expression; Humans; Hypoglycemic Agents; Intra-Abdominal Fat; Male; Membrane Proteins; Middle Aged; Obesity; Oxidoreductases; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones; Tumor Necrosis Factor-alpha	2011
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation. Nature, 2011, Sep-04, Volume: 477, Issue:7365 Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Animals; Biphenyl Compounds; Body Fluids; Chlorocebus aethiops; COS Cells; Cyclin-Dependent Kinase 5; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Hypoglycemic Agents; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Models, Molecular; Obesity; Osteogenesis; Phosphorylation; Phosphoserine; PPAR gamma; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Tumor Necrosis Factor-alpha; Weight Gain	2011
Metabolic stress-induced inflammation plays a major role in the development of osteoarthritis in mice. Arthritis and rheumatism, 2012, Volume: 64, Issue:4 Topics: Animals; Body Weight; C-Reactive Protein; Cytokines; Diet, High-Fat; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Inflammation; Insulin; Male; Mice; Mice, Transgenic; Obesity; Osteoarthritis; Pyrimidines; Rosiglitazone; Rosuvastatin Calcium; Sulfonamides; Thiazolidinediones	2012
Unmasking differential effects of rosiglitazone and pioglitazone in the combination treatment with n-3 fatty acids in mice fed a high-fat diet. PloS one, 2011, Volume: 6, Issue:11 Topics: Animals; Blood Glucose; Dietary Fats; Fatty Acids, Omega-3; Homeostasis; Hypoglycemic Agents; Lipids; Male; Metabolomics; Mice; Mice, Inbred C57BL; Obesity; Pioglitazone; Rosiglitazone; Thiazolidinediones	2011
Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells. PloS one, 2012, Volume: 7, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adipose Tissue; Animals; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Epoprostenol; Gene Expression Profiling; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Humans; Insulin; Mesenchymal Stem Cells; Mice; Obesity; Rosiglitazone; Signal Transduction; Thiazolidinediones	2012
Early induction of a brown-like phenotype by rosiglitazone in the epicardial adipose tissue of fatty Zucker rats. Biochimie, 2012, Volume: 94, Issue:8 Topics: Adipose Tissue, Brown; Animals; Fatty Acids; Gene Expression Regulation; Insulin Resistance; Intra-Abdominal Fat; Lipid Metabolism; Mitochondria, Heart; Obesity; Pericardium; Phenotype; PPAR gamma; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones	2012
Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione. The Journal of biological chemistry, 2012, Jul-06, Volume: 287, Issue:28 Topics: 3T3-L1 Cells; Animals; Binding, Competitive; Cells, Cultured; Female; Gene Expression; Glycolysis; Hep G2 Cells; Hepatocytes; Humans; Hypoglycemic Agents; Insulin Resistance; Lipogenesis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Molecular Structure; Obesity; Pioglitazone; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones	2012
Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes. Experimental & molecular medicine, 2012, Sep-30, Volume: 44, Issue:9 Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Adipose Tissue; Animals; Endoplasmic Reticulum Stress; Insulin Resistance; Mice; Mitochondria; Mitochondrial Turnover; Nitric Oxide Synthase Type II; Nuclear Respiratory Factor 1; Obesity; Palmitic Acid; Rosiglitazone; Thiazolidinediones	2012
Rosiglitazone improves insulin sensitivity and baroreflex gain in rats with diet-induced obesity. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:1 Topics: Animals; Baroreflex; Diet, High-Fat; Insulin Resistance; Male; Obesity; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Vasodilator Agents	2012
Preservation of metabolic flexibility in skeletal muscle by a combined use of n-3 PUFA and rosiglitazone in dietary obese mice. PloS one, 2012, Volume: 7, Issue:8 Topics: Animals; Diet, High-Fat; Drug Synergism; Fatty Acids, Omega-3; Gene Expression Regulation; Glycolysis; Male; Metabolomics; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Oxidation-Reduction; Rosiglitazone; Thiazolidinediones	2012
Negative regulation of adipogenesis by kaempferol, a component of Rhizoma Polygonati falcatum in 3T3-L1 cells. Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:9 Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Drugs, Chinese Herbal; Homeostasis; Hypoglycemic Agents; Kaempferols; Lipid Metabolism; Lipolysis; Mice; Microarray Analysis; Obesity; Phytotherapy; Polygonatum; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rhizome; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription Factors; Triglycerides	2012
META060 protects against diet-induced obesity and insulin resistance in a high-fat-diet fed mouse. Nutrition (Burbank, Los Angeles County, Calif.), 2013, Volume: 29, Issue:1 Topics: Animals; Body Composition; Diet, High-Fat; Dietary Supplements; Glucose Tolerance Test; Humulus; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Phytotherapy; Plant Extracts; Rosiglitazone; Thiazolidinediones	2013
Quantitative histopathological assessment of retardation of islets of langerhans degeneration in rosiglitazone-dosed obese ZDF rats using combined insulin and collagens (I and III) immunohistochemistry with automated image analysis and statistical modelin Toxicologic pathology, 2013, Volume: 41, Issue:3 Topics: Algorithms; Animals; Collagen Type I; Collagen Type III; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Image Processing, Computer-Assisted; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Models, Statistical; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones	2013
Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor γ agonist improve vascular function and decrease renal injury in hypertensive obese rats. Experimental biology and medicine (Maywood, N.J.), 2012, Volume: 237, Issue:12 Topics: Albuminuria; Animals; Blood Pressure; Cardiomegaly; Epoxide Hydrolases; Hypertension; Hypoglycemic Agents; Kidney Glomerulus; Macrophages; Male; Obesity; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rosiglitazone; Species Specificity; Syndrome; Thiazolidinediones	2012
Weight loss improves the adipogenic capacity of human preadipocytes and modulates their secretory profile. Diabetes, 2013, Volume: 62, Issue:6 Topics: Adipocytes; Adipogenesis; Adiponectin; Cells, Cultured; Chemokine CCL2; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukin-8; Leptin; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Weight Loss	2013
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists. Diabetes, 2002, Volume: 51, Issue:8 Topics: Adipose Tissue; Animals; Fatty Acids, Nonesterified; Female; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors	2002
Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6 Topics: Animals; Benzazepines; Binding, Competitive; Blood Glucose; Blood Pressure; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Glucose; Hyperinsulinism; Hypoglycemic Agents; Insulin; Kidney; Kidney Tubules, Proximal; Male; Obesity; Rats; Rats, Zucker; Receptors, Dopamine D1; Rosiglitazone; Sodium-Potassium-Exchanging ATPase; Thiazoles; Thiazolidinediones	2002
Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty rats. Diabetes, 2003, Volume: 52, Issue:1 Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Insulin Resistance; Lipid Metabolism; Liver; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Obesity; Organ Size; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors	2003
Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation. The Journal of biological chemistry, 2003, Apr-04, Volume: 278, Issue:14 Topics: Adipocytes; Animals; Blood Vessels; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Diet; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Matrix Metalloproteinases, Membrane-Associated; Matrix Metalloproteinases, Secreted; Metalloendopeptidases; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Obese; Mitosis; Obesity; Phenylalanine; Protease Inhibitors; RNA, Messenger; Rosiglitazone; Stromal Cells; Thiazoles; Thiazolidinediones; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-3	2003
Reduction of intramyocellular lipid following short-term rosiglitazone treatment in Zucker fatty rats: an in vivo nuclear magnetic resonance study. Metabolism: clinical and experimental, 2003, Volume: 52, Issue:2 Topics: Animals; Blood Glucose; Insulin; Lipid Metabolism; Lipids; Magnetic Resonance Spectroscopy; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides; Weight Gain	2003
[Therapy decision based on the glucose triad. Drug treatment of type 2 diabetes]. MMW Fortschritte der Medizin, 2003, Feb-27, Volume: 145, Issue:9 Topics: 1-Deoxynojirimycin; Acarbose; Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Glucosamine; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin Resistance; Insulin Secretion; Metformin; Obesity; Pioglitazone; Risk Factors; Rosiglitazone; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Time Factors	2003
[When HbA1c cannot be pushed down under 7. Don't hesitate to use a 2d antidiabetic agent]. MMW Fortschritte der Medizin, 2003, Mar-06, Volume: 145, Issue:10 Topics: Diabetes Mellitus; Drug Therapy, Combination; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones	2003
Rapid reversal of hepatic steatosis, and reduction of muscle triglyceride, by rosiglitazone: MRI/S studies in Zucker fatty rats. Diabetes, obesity & metabolism, 2003, Volume: 5, Issue:4 Topics: Animals; Fatty Liver; Hepatomegaly; Hypoglycemic Agents; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides	2003
Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice. Proteomics, 2003, Volume: 3, Issue:8 Topics: Animals; Electrophoresis, Gel, Two-Dimensional; Hypoglycemic Agents; Insulin Resistance; Leptin; Mice; Mice, Inbred C57BL; Obesity; Rosiglitazone; Thiazolidinediones	2003
Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation. Diabetes, 2003, Volume: 52, Issue:9 Topics: Adipose Tissue; Animals; Basal Metabolism; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids; Fenofibrate; Glycogen; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Islets of Langerhans; Male; Muscle, Skeletal; Obesity; Rats; Rats, Inbred OLETF; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Viscera	2003
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. The Journal of clinical investigation, 2003, Volume: 112, Issue:12 Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Cells, Cultured; Down-Regulation; Gene Expression Regulation; Giant Cells; Immunohistochemistry; In Situ Hybridization; Inflammation; Insulin Resistance; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Models, Biological; Neutrophils; Obesity; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors; Up-Regulation	2003
Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease. Annals of surgery, 2004, Volume: 239, Issue:1 Topics: Anastomosis, Surgical; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Duodenum; Eating; Follow-Up Studies; Gastric Bypass; Glucose Tolerance Test; Jejunum; Male; Obesity; Probability; Random Allocation; Rats; Rats, Inbred Strains; Reference Values; Rosiglitazone; Thiazolidinediones; Weight Loss	2004
Rosiglitazone restores G-protein coupling, recruitment, and function of renal dopamine D1A receptor in obese Zucker rats. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Blood Glucose; Cell Membrane; Colforsin; Dopamine; Heterotrimeric GTP-Binding Proteins; Insulin; Insulin Resistance; Kidney Tubules, Proximal; Male; Obesity; Protein Transport; Rats; Rats, Zucker; Receptors, Dopamine D1; Rosiglitazone; Sodium; Thiazolidinediones; Urine	2004
[An overweight diabetic does not tolerate metformin. Insulin sensitizer can be prescribed alone, too]. MMW Fortschritte der Medizin, 2003, Dec-04, Volume: 145, Issue:49 Topics: Blood Glucose; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Placebos; Risk Factors; Rosiglitazone; Thiazolidinediones; Time Factors	2003
Visceral obesity without insulin resistance in late-onset obesity rats. Endocrinology, 2004, Volume: 145, Issue:6 Topics: Absorption; Animals; Animals, Genetically Modified; Body Temperature; Diet; Dietary Fats; Disease Susceptibility; Eating; Estradiol; Female; Glucose; Growth Hormone; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Obesity; Ovariectomy; Phenotype; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Time Factors; Viscera	2004
Increased adipose tissue expression of Grb14 in several models of insulin resistance. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:9 Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adipocytes; Adipose Tissue; Animals; Carrier Proteins; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Gene Expression Regulation; Insulin; Insulin Resistance; Liver; Metformin; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscles; Obesity; Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones	2004
Effects of PPARgamma and PPARalpha agonists on serum leptin levels in diet-induced obese rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2004, Volume: 36, Issue:4 Topics: Adipose Tissue; Animals; Dietary Fats; Energy Metabolism; Gemfibrozil; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Leptin; Male; Obesity; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Weight Gain	2004
Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro. The Journal of biological chemistry, 2004, Jul-09, Volume: 279, Issue:28 Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Animals; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Diet; Dietary Fats; Gene Expression Regulation; Hypoglycemic Agents; Lipid Metabolism; Lipodystrophy; Male; Mice; Mice, Inbred BALB C; Nuclear Proteins; Obesity; Phosphatidate Phosphatase; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription Factors	2004
Rosiglitazone enhances glucose tolerance by mechanisms other than reduction of fatty acid accumulation within skeletal muscle. Endocrinology, 2004, Volume: 145, Issue:12 Topics: Animals; Diglycerides; Fatty Acids; Female; Glucose Intolerance; Hypoglycemic Agents; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones; Triglycerides	2004
Effects of rosiglitazone in obese women with polycystic ovary syndrome and severe insulin resistance. The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:1 Topics: Androgens; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Luteinizing Hormone; Obesity; Ovary; Polycystic Ovary Syndrome; Rosiglitazone; Thiazolidinediones	2005
Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone. The Journal of clinical investigation, 2004, Volume: 114, Issue:9 Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Blood Glucose; Blotting, Northern; Blotting, Western; Chaperonin 60; Fatty Acids; Insulin; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Obese; Mice, Transgenic; Microscopy, Fluorescence; Mitochondria; Obesity; Oligonucleotide Array Sequence Analysis; Oxygen; Palmitic Acid; PPAR gamma; RNA, Complementary; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors; Vasodilator Agents	2004
Revised vs original QUICKI index during diet + rosiglitazone treatment in obese subjects. Diabetes & metabolism, 2004, Volume: 30, Issue:5 Topics: Body Mass Index; Diet, Reducing; Humans; Hypoglycemic Agents; Insulin Resistance; Monitoring, Physiologic; Obesity; Rosiglitazone; Thiazolidinediones; Weight Loss	2004
Gene expression and adiposity are modified by soy protein in male Zucker diabetic fatty rats. Obesity research, 2004, Volume: 12, Issue:12 Topics: Adipose Tissue; Animals; Body Composition; Caseins; Diabetes Mellitus; Diet; Dietary Proteins; Gene Expression; Hypoglycemic Agents; Isoflavones; Lipids; Liver; Male; Obesity; Organ Size; Polymerase Chain Reaction; Rats; Rats, Zucker; RNA, Messenger; Rosiglitazone; Soybean Proteins; Thiazolidinediones	2004
Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone. Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:2 Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Drinking; Drug Therapy, Combination; Drug Tolerance; Eating; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Obesity; Pentanoic Acids; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Time Factors	2005
Divergent effects of rosiglitazone on protein-mediated fatty acid uptake in adipose and in muscle tissues of Zucker rats. Journal of lipid research, 2005, Volume: 46, Issue:6 Topics: Adipocytes; Adipose Tissue; Animals; CD36 Antigens; Cell Membrane; Fatty Acid Transport Proteins; Fatty Acids; Female; Hypoglycemic Agents; Membrane Transport Proteins; Muscle, Skeletal; Muscles; Obesity; Palmitic Acid; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones; Triglycerides	2005
Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1 Topics: 3T3 Cells; Adipocytes; Animals; Biotransformation; Blood Glucose; Cell Differentiation; Cholic Acids; Diabetes Mellitus, Type 2; Dogs; Drug Synergism; Estrone; Glucocorticoids; Glucose; Glutamate-Ammonia Ligase; Hypoglycemic Agents; Liver; Male; Mice; Obesity; Prednisolone; Rats; Rats, Zucker; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Tyrosine Transaminase	2005
S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes, 2005, Volume: 54, Issue:4 Topics: Animals; Glutathione; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred NOD; Muscle, Skeletal; Nitric Oxide; Nitro Compounds; Nitrosation; Obesity; Phosphoproteins; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Insulin; Rosiglitazone; Thiazolidinediones	2005
Rosiglitazone restores renal D1A receptor-Gs protein coupling by reducing receptor hyperphosphorylation in obese rats. American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:2 Topics: Animals; beta-Adrenergic Receptor Kinases; Blood Glucose; Blood Pressure; Body Weight; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; G-Protein-Coupled Receptor Kinase 4; GTP-Binding Protein alpha Subunits, Gs; Immunoprecipitation; Insulin; Insulin Resistance; Kidney Tubules, Proximal; Male; Obesity; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Zucker; Receptors, Dopamine D1; Receptors, G-Protein-Coupled; Rosiglitazone; Thiazolidinediones	2005
Regulation of the renal thiazide-sensitive Na-Cl cotransporter, blood pressure, and natriuresis in obese Zucker rats treated with rosiglitazone. American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:2 Topics: Aging; Animals; Blood Glucose; Blood Pressure; Body Weight; Glucose Tolerance Test; Hypoglycemic Agents; Immunoblotting; Immunoenzyme Techniques; Kidney; Male; Natriuresis; Obesity; PPAR gamma; Proteinuria; Rats; Rats, Zucker; Receptors, Drug; Rosiglitazone; Sodium Chloride; Sodium Chloride Symporters; Solute Carrier Family 12, Member 3; Symporters; Telemetry; Thiazolidinediones; Tissue Distribution	2005
Insulin-mediated upregulation of the renin angiotensin system in human subcutaneous adipocytes is reduced by rosiglitazone. Circulation, 2005, Apr-19, Volume: 111, Issue:15 Topics: Adipocytes; Angiotensin II; Antihypertensive Agents; Cells, Cultured; Drug Antagonism; Humans; Insulin; Obesity; Renin-Angiotensin System; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha; Up-Regulation	2005
Free fatty acid-induced insulin resistance in the obese is not prevented by rosiglitazone treatment. The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:9 Topics: Adult; C-Reactive Protein; Drug Combinations; Emulsions; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Heparin; Humans; Infusion Pumps; Insulin Resistance; Male; Middle Aged; Obesity; Rosiglitazone; Serum Amyloid A Protein; Thiazolidinediones; Triglycerides	2005
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature, 2005, Jul-21, Volume: 436, Issue:7049 Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation; Glucose Transporter Type 4; Hepatocytes; Insulin; Insulin Resistance; Liver; Mice; Mice, Knockout; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Obesity; Oligonucleotide Array Sequence Analysis; Phosphoenolpyruvate Carboxykinase (GTP); Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Rosiglitazone; Signal Transduction; Thiazolidinediones	2005
Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals. Diabetes, 2005, Volume: 54, Issue:8 Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Female; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Male; Metabolic Clearance Rate; Middle Aged; Obesity; Rosiglitazone; Thiazolidinediones	2005
Chronic rosiglitazone treatment restores AMPKalpha2 activity in insulin-resistant rat skeletal muscle. American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:2 Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Female; Hypoglycemic Agents; Insulin Resistance; Multienzyme Complexes; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Protein Serine-Threonine Kinases; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones	2006
Increased A-ring reduction of glucocorticoids in obese Zucker rats: effects of insulin sensitization. Obesity research, 2005, Volume: 13, Issue:9 Topics: Animals; Cholestenone 5 alpha-Reductase; Glucocorticoids; Hypoglycemic Agents; Insulin; Liver; Metformin; Obesity; Oxidoreductases; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones	2005
PPAR-gamma response element activity in intact primary human adipocytes: effects of fatty acids. Nutrition (Burbank, Los Angeles County, Calif.), 2006, Volume: 22, Issue:1 Topics: Adipocytes; Cells, Cultured; Diabetes Mellitus, Type 2; Fatty Acid Transport Proteins; Fatty Acids; Female; Gene Expression Regulation; Humans; Hypoglycemic Agents; Luciferases; Middle Aged; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Transfection	2006
Differential endocrine responses to rosiglitazone therapy in new mouse models of type 2 diabetes. Endocrinology, 2006, Volume: 147, Issue:2 Topics: Adiponectin; Analysis of Variance; Animals; Biomarkers; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Glucose Intolerance; Hypoglycemic Agents; Insulin; Leptin; Male; Mice; Mice, Congenic; Mice, Inbred NOD; Mice, Obese; Obesity; Phenotype; Plasminogen Activator Inhibitor 1; Quantitative Trait, Heritable; Recombination, Genetic; Resistin; Rosiglitazone; Species Specificity; Syndrome; Thiazolidinediones	2006
Biological characterization of a heterodimer-selective retinoid X receptor modulator: potential benefits for the treatment of type 2 diabetes. Endocrinology, 2006, Volume: 147, Issue:2 Topics: Analysis of Variance; Animals; Apolipoprotein A-I; Area Under Curve; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Interactions; Fatty Acids, Unsaturated; Female; Hypoglycemic Agents; Mice; Mice, Transgenic; Obesity; Phenyl Ethers; PPAR gamma; Rats; Rats, Sprague-Dawley; Rats, Zucker; Retinoid X Receptors; Rosiglitazone; Statistics, Nonparametric; Thiazolidinediones; Thyroid Gland; Triglycerides	2006
Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination. Diabetes, 2005, Volume: 54, Issue:12 Topics: Animals; Blood Glucose; Epididymis; Glucose Tolerance Test; Hypoglycemic Agents; Inflammation; Insulin Resistance; Male; Mice; Mice, Inbred Strains; Obesity; Polymerase Chain Reaction; PPAR alpha; PPAR gamma; Pyrimidines; Receptors, Adiponectin; Receptors, Cell Surface; Rosiglitazone; Thiazolidinediones	2005
(+)-Z-Bisdehydrodoisynolic acid ameliorates obesity and the metabolic syndrome in female ZDF rats. Obesity research, 2005, Volume: 13, Issue:11 Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Coronary Vessels; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Gene Expression; Hypoglycemic Agents; Kidney; Liver; Metabolic Syndrome; Obesity; Organ Size; Phenanthrenes; PPAR alpha; PPAR gamma; Random Allocation; Rats; Rats, Zucker; Risk Factors; Rosiglitazone; Selective Estrogen Receptor Modulators; Thiazolidinediones; Triglycerides	2005
Muraglitazar, a novel dual (alpha/gamma) peroxisome proliferator-activated receptor activator, improves diabetes and other metabolic abnormalities and preserves beta-cell function in db/db mice. Diabetes, 2006, Volume: 55, Issue:1 Topics: Adiponectin; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Type 2; Diet; Female; Glycine; Hyperlipidemias; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Liver; Mice; Obesity; Oxazoles; Peroxisome Proliferator-Activated Receptors; Rosiglitazone; Thiazolidinediones	2006
Reduced skeletal muscle uncoupling protein-3 content in prediabetic subjects and type 2 diabetic patients: restoration by rosiglitazone treatment. The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:4 Topics: Aged; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Type 2; Glucose Clamp Technique; Glucose Intolerance; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Ion Channels; Male; Middle Aged; Mitochondrial Proteins; Muscle, Skeletal; Obesity; Prediabetic State; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Uncoupling Protein 3	2006
The effects of rosiglitazone and metformin on insulin resistance and serum androgen levels in obese and lean patients with polycystic ovary syndrome. Journal of endocrinological investigation, 2005, Volume: 28, Issue:11 Topics: Adult; Androgens; Blood Glucose; Body Mass Index; Fasting; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Hirsutism; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Luteinizing Hormone; Menstrual Cycle; Menstruation; Metformin; Obesity; Polycystic Ovary Syndrome; Rosiglitazone; Thiazolidinediones; Thinness	2005
The effect of rosiglitazone on overweight subjects with type 1 diabetes. Diabetes care, 2006, Volume: 29, Issue:3 Topics: Blood Pressure; Diabetes Mellitus, Type 1; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Obesity; Rosiglitazone; Thiazolidinediones; Waist-Hip Ratio	2006
Optimal treatments for the metabolic syndrome. Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:4 Topics: Anti-Obesity Agents; Cardiovascular Diseases; Complementary Therapies; Diabetes Mellitus; Diet; Health Behavior; Humans; Hypoglycemic Agents; Life Style; Metabolic Syndrome; Metformin; Obesity; Piperidines; Pyrazoles; Randomized Controlled Trials as Topic; Rimonabant; Rosiglitazone; Thiazolidinediones	2006
Apolipoprotein AV does not contribute to hypertriglyceridaemia or triglyceride lowering by dietary fish oil and rosiglitazone in obese Zucker rats. Diabetologia, 2006, Volume: 49, Issue:6 Topics: Animals; Apolipoprotein A-V; Apolipoproteins; Base Sequence; Cholesterol; Dietary Fats; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fish Oils; Hypertriglyceridemia; Insulin; Molecular Sequence Data; Obesity; PPAR gamma; Rats; Rats, Zucker; RNA, Messenger; Rosiglitazone; Sequence Alignment; Sequence Homology, Nucleic Acid; Thiazolidinediones; Triglycerides	2006
Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature, 2006, Apr-13, Volume: 440, Issue:7086 Topics: 3T3-L1 Cells; Animals; Antioxidants; Body Weight; Catalase; Glucose Tolerance Test; Insulin Resistance; Male; Metalloporphyrins; Mice; Mice, Obese; Obesity; Oxidation-Reduction; Reactive Oxygen Species; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones; Transgenes	2006
Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:8 Topics: Adipose Tissue; Animals; Capillary Permeability; Diabetes Mellitus; Edema; Enzyme Activation; Enzyme Inhibitors; Hypoglycemic Agents; Indoles; Male; Maleimides; Mice; Mice, Knockout; Obesity; PPAR gamma; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Receptor, Insulin; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factor A; Weight Gain	2006
A selective peroxisome proliferator-activated receptor gamma modulator with distinct fat cell regulation properties. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3T3 Cells; Adipocytes; Animals; Benzimidazoles; Cell Differentiation; Chlorocebus aethiops; Collagen; Cyclic Nucleotide Phosphodiesterases, Type 3; Gels; Gene Expression; Hypoglycemic Agents; Insulin Resistance; Mice; Obesity; Pioglitazone; Plasmids; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Triglycerides	2006
Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo. Biochemical pharmacology, 2006, Jun-28, Volume: 72, Issue:1 Topics: 3T3-L1 Cells; Adipocytes; Anilides; Animals; Binding, Competitive; Body Weight; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Glucose Tolerance Test; Hepatocytes; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones	2006
Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PLoS medicine, 2006, Volume: 3, Issue:6 Topics: Adipocytes; Adipose Tissue; Animals; Biomarkers; Cardiovascular Diseases; Cell Line; Clinical Trials as Topic; Cross-Sectional Studies; Cytokines; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Inflammation; Lipolysis; Male; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; Risk Factors; RNA, Messenger; Rosiglitazone; Serum Amyloid A Protein; Stromal Cells; Thiazolidinediones	2006
The PPARalpha/gamma dual agonist chiglitazar improves insulin resistance and dyslipidemia in MSG obese rats. British journal of pharmacology, 2006, Volume: 148, Issue:5 Topics: Adipose Tissue; Animals; Blood Glucose; Carbazoles; Disease Models, Animal; Dyslipidemias; Gene Expression; Gluconeogenesis; Hypoglycemic Agents; Insulin Resistance; Lipids; Liver; Liver Glycogen; Muscles; Obesity; Pancreas; Pioglitazone; PPAR alpha; PPAR gamma; Propionates; Pyrimidines; Rats; Rats, Wistar; Rosiglitazone; Sodium Glutamate; Thiazolidinediones	2006
Rosiglitazone regulates ENaC and Na-K-2Cl cotransporter (NKCC2) abundance in the obese Zucker rat. American journal of nephrology, 2006, Volume: 26, Issue:3 Topics: Animals; Diabetes Mellitus, Type 2; Epithelial Sodium Channels; Gene Expression Regulation; Kidney; Male; Obesity; Random Allocation; Rats; Rats, Zucker; Rosiglitazone; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Thiazolidinediones; Tissue Distribution	2006
Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists. Vascular pharmacology, 2006, Volume: 45, Issue:3 Topics: 3T3-L1 Cells; Adipogenesis; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Chlorocebus aethiops; Dose-Response Relationship, Drug; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Obese; Obesity; PPAR gamma; Promoter Regions, Genetic; Recombinant Proteins; Rosiglitazone; Structure-Activity Relationship; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transfection	2006
Low-dose rosiglitazone exerts an antiinflammatory effect with an increase in adiponectin independently of free fatty acid fall and insulin sensitization in obese type 2 diabetics. The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:9 Topics: Adiponectin; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Leukocyte Count; Male; Matrix Metalloproteinase 9; Middle Aged; Obesity; Resistin; Rosiglitazone; Serum Amyloid A Protein; Thiazolidinediones	2006
Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. Diabetes, 2006, Volume: 55, Issue:8 Topics: Acetyl-CoA Carboxylase; Acyl Coenzyme A; Adult; AMP-Activated Protein Kinases; Carboxy-Lyases; Diabetes Mellitus, Type 2; Fatty Acid Transport Proteins; Fatty Acids; Female; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Male; Malonyl Coenzyme A; Middle Aged; Mitochondria, Muscle; Multienzyme Complexes; Muscle, Skeletal; Obesity; Oxidation-Reduction; Protein Serine-Threonine Kinases; Rosiglitazone; Thiazolidinediones; Triglycerides	2006
JTP-426467 acts as a selective antagonist for peroxisome proliferator-activated receptor gamma in vitro and in vivo. Diabetes, obesity & metabolism, 2006, Volume: 8, Issue:5 Topics: Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Benzoxazoles; Blood Glucose; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; HeLa Cells; Humans; Hypoglycemic Agents; Leptin; Male; Mice; Obesity; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Weight Gain	2006
Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans. Clinical chemistry, 2007, Volume: 53, Issue:1 Topics: Acute-Phase Proteins; Adult; Age Factors; Aged; Animals; Biomarkers; Body Mass Index; C-Reactive Protein; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hyperglycemia; Inflammation; Insulin Resistance; Lipocalin-2; Lipocalins; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Middle Aged; Obesity; Oncogene Proteins; Polymerase Chain Reaction; PPAR gamma; Proto-Oncogene Proteins; Rosiglitazone; Sex Factors; Thiazolidinediones	2007
Peroxisome proliferator activated receptor gamma activity is low in mature primary human visceral adipocytes. Diabetologia, 2007, Volume: 50, Issue:1 Topics: Adipocytes; Adult; Aged; Aged, 80 and over; Animals; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Intra-Abdominal Fat; Luciferases, Firefly; Male; Mice; Mice, Inbred Strains; Middle Aged; Obesity; PPAR gamma; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones; Transfection	2007
Lipocalins and insulin resistance: etiological role of retinol-binding protein 4 and lipocalin-2? Clinical chemistry, 2007, Volume: 53, Issue:1 Topics: Acute-Phase Proteins; Adipose Tissue; Animals; Body Mass Index; C-Reactive Protein; Humans; Inflammation; Insulin Resistance; Lipocalin-2; Lipocalins; Liver; Mice; Mice, Obese; Obesity; Oncogene Proteins; PPAR gamma; Proto-Oncogene Proteins; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Rosiglitazone; Thiazolidinediones	2007
Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice. American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:6 Topics: Adipocytes; Adiponectin; Adipose Tissue; Adiposity; Animals; Apoptosis; Body Weight; Dietary Fats; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Hypoglycemic Agents; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Leptin; Linoleic Acids, Conjugated; Lipid Metabolism; Lipoproteins, VLDL; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors; Triglycerides	2007
Soy protein and isoflavones influence adiposity and development of metabolic syndrome in the obese male ZDF rat. Annals of nutrition & metabolism, 2007, Volume: 51, Issue:1 Topics: Adiposity; Animals; Blood Glucose; Caseins; Hypoglycemic Agents; Isoflavones; Kidney Diseases; Liver; Male; Metabolic Syndrome; Milk Proteins; Obesity; Proteinuria; Rats; Rats, Inbred Strains; Rosiglitazone; Soybean Proteins; Thiazolidinediones	2007
Mechanism by which a novel non-thiazolidinedione peroxisome proliferator-activated receptor gamma agonist, FK614, ameliorates insulin resistance in Zucker fatty rats. Diabetes, obesity & metabolism, 2007, Volume: 9, Issue:3 Topics: Acyl-CoA Oxidase; Adipocytes, White; Adipose Tissue; Administration, Oral; Animals; Benzimidazoles; Biological Transport; Cell Count; Cell Size; Epididymis; Fatty Acid-Binding Proteins; Gene Expression; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Pioglitazone; PPAR gamma; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones	2007
Metabolic syndrome: a work in progress, but a useful construct. Circulation, 2007, Apr-03, Volume: 115, Issue:13 Topics: Abdominal Fat; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Cohort Studies; Coronary Disease; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin Resistance; Metabolic Syndrome; Models, Biological; Obesity; Prognosis; Risk Factors; Rosiglitazone; Thiazolidinediones	2007
Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone. Diabetes, 2007, Volume: 56, Issue:7 Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Transcription, Genetic	2007
Preventing diabetes, Part II: an action plan. Harvard men's health watch, 2007, Volume: 11, Issue:12 Topics: Diabetes Mellitus; Diet; Exercise; Humans; Hypoglycemic Agents; Life Style; Metformin; Obesity; Rosiglitazone; Smoking; Thiazolidinediones; Weight Loss	2007
The endogenous cannabinoid system stimulates glucose uptake in human fat cells via phosphatidylinositol 3-kinase and calcium-dependent mechanisms. The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:12 Topics: Adipocytes; Adipose Tissue; Adult; Body Mass Index; Calcium; Cannabinoid Receptor Modulators; Cell Differentiation; Female; Glucose; Humans; Hypoglycemic Agents; Male; Microscopy, Confocal; Obesity; Phosphatidylinositol 3-Kinases; PPAR gamma; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; RNA; Rosiglitazone; Thiazolidinediones	2007
Essential role of mitochondrial function in adiponectin synthesis in adipocytes. Diabetes, 2007, Volume: 56, Issue:12 Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Endoplasmic Reticulum; Epididymis; Fatty Acids, Nonesterified; Gene Expression Regulation; Male; Mice; Mice, Obese; Mitochondria; Obesity; Oxygen Consumption; RNA, Messenger; Rosiglitazone; Stress, Physiological; Thiazolidinediones	2007
Weight gain may contribute to increased fracture risk in women treated with rosiglitazone. Diabetic medicine : a journal of the British Diabetic Association, 2007, Volume: 24, Issue:10 Topics: Animals; Diabetes Complications; Female; Fractures, Bone; Humans; Mice; Middle Aged; Obesity; Rats; Rosiglitazone; Thiazolidinediones	2007
The peroxisome proliferator activated receptor gamma (PPARgamma) ligand rosiglitazone modulates bronchoalveolar lavage levels of leptin, adiponectin, and inflammatory cytokines in lean and obese mice. Lung, 2007, Volume: 185, Issue:6 Topics: Adiponectin; Animals; Biomarkers; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hypoglycemic Agents; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Treatment Outcome	2007
Avandia in perspective. U.S. news & world report, 2007, Oct-01, Volume: 143, Issue:11 Topics: Blood Glucose; Diabetes Mellitus; Exercise; Health Behavior; Heart Failure; Humans; Hypoglycemic Agents; Myocardial Infarction; Obesity; Risk-Taking; Rosiglitazone; Thiazolidinediones; United States	2007
Effect of metformin and rosiglitazone in a prepubertal boy with Alström syndrome. Journal of pediatric endocrinology & metabolism : JPEM, 2007, Volume: 20, Issue:9 Topics: Abnormalities, Multiple; Child; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fatty Liver; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Obesity; Rosiglitazone; Syndrome; Thiazolidinediones	2007
[Vascular dysfunction in metabolic disorders: evaluation of some therapeutic interventions]. Bulletin de l'Academie nationale de medecine, 2007, Volume: 191, Issue:3 Topics: Adolescent; Adult; Capillary Permeability; Case-Control Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypoglycemic Agents; Metabolic Syndrome; Metformin; Microcirculation; Microscopic Angioscopy; Obesity; Plethysmography; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Vasodilator Agents	2007
Energy restriction enhances therapeutic efficacy of the PPARgamma agonist, rosiglitazone, through regulation of visceral fat gene expression. Diabetes, obesity & metabolism, 2008, Volume: 10, Issue:3 Topics: Animals; Energy Intake; Gene Expression; Hypoglycemic Agents; Insulin Resistance; Intra-Abdominal Fat; Male; Obesity; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones	2008
Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone reverses the adverse effects of diet-induced obesity on oocyte quality. Endocrinology, 2008, Volume: 149, Issue:5 Topics: Animals; Blastomeres; Cell Differentiation; Cells, Cultured; Cytoprotection; Diet; Diet, Atherogenic; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Gene Expression Regulation; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Obesity; Oocytes; Ovary; Ovulation; PPAR gamma; Rosiglitazone; Thiazolidinediones	2008
Insulin resistance and impaired functional vasodilation in obese Zucker rats. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4 Topics: Animals; Antioxidants; Arachidonic Acid; Arterioles; Blood Glucose; Bridged Bicyclo Compounds, Heterocyclic; Cyclic N-Oxides; Disease Models, Animal; Electric Stimulation; Fatty Acids, Unsaturated; Hydrazines; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Insulin; Insulin Resistance; Kidney Cortex; Male; Muscle, Skeletal; NADPH Oxidases; Obesity; Oxidative Stress; Rats; Rats, Zucker; Receptors, Thromboxane; Rosiglitazone; Spin Labels; Superoxides; Thiazolidinediones; Thromboxanes; Time Factors; Triglycerides; Vasoconstriction; Vasodilation	2008
Re: "Effect of metformin and rosiglitazone in a prepubertal boy with Alström syndrome", Sinha SK et al., JPEM 2007; 20: 1045-1052. Journal of pediatric endocrinology & metabolism : JPEM, 2008, Volume: 21, Issue:1 Topics: Child; Deafness; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Male; Metformin; Nystagmus, Congenital; Obesity; Retinitis Pigmentosa; Rosiglitazone; Syndrome; Thiazolidinediones	2008
The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice. Life sciences, 2008, May-07, Volume: 82, Issue:19-20 Topics: Animals; Dietary Fats; Disease Models, Animal; Fatty Acids; Fatty Liver; Fenofibrate; Gene Expression; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones	2008
Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Diabetes, 2008, Volume: 57, Issue:8 Topics: 3T3-L1 Cells; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Blotting, Western; Body Weight; Dietary Fats; Female; Genotype; Glucose Tolerance Test; Insulin; Insulin Resistance; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Nitric Oxide Synthase Type II; Obesity; Phosphorylation; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones	2008
Treatment options in insulin resistance obesity-related acanthosis nigricans. The Annals of pharmacotherapy, 2008, Volume: 42, Issue:7 Topics: Acanthosis Nigricans; Adolescent; Adult; Calcitriol; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Octreotide; Retinoids; Rosiglitazone; Thiazolidinediones; Vitamin D	2008
Impact of increased PPARgamma activity in adipocytes in vivo on adiposity, insulin sensitivity and the effects of rosiglitazone treatment. Endocrine journal, 2008, Volume: 55, Issue:4 Topics: Adipocytes; Adipose Tissue, White; Animals; Dietary Fats; Insulin Resistance; Male; Mice; Mice, Transgenic; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones	2008
Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes. Proceedings of the National Academy of Sciences of the United States of America, 1996, Jun-11, Volume: 93, Issue:12 Topics: 3T3 Cells; Adipocytes; Animals; Base Sequence; Gene Expression Regulation; Hypoglycemic Agents; Leptin; Mice; Molecular Sequence Data; Obesity; Oligodeoxyribonucleotides; Protein Binding; Proteins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors	1996
Effect of the thiazolidinedione BRL49653 and genetic obesity on hepatic gene expression in the Zucker rat. Biochemical Society transactions, 1995, Volume: 23, Issue:4 Topics: Animals; Cell Line; Gene Expression; Hypoglycemic Agents; Liver; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Zucker; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones	1995
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature, 1997, Mar-27, Volume: 386, Issue:6623 Topics: Animals; Bexarotene; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Resistance; Ligands; Mice; Mice, Inbred C57BL; Mice, Obese; Nicotinic Acids; Obesity; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection	1997
Novel benzoxazole 2,4-thiazolidinediones as potent hypoglycemic agents. Synthesis and structure-activity relationships. Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:12 Topics: Animals; Benzopyrans; Benzoxazoles; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Male; Mice; Obesity; Pioglitazone; Rosiglitazone; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Troglitazone	1997
Peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats. Diabetes, 1998, Volume: 47, Issue:8 Topics: Acetylglucosaminidase; Albuminuria; Animals; Blood Pressure; Body Weight; Histocytochemistry; Hypoglycemic Agents; Immunohistochemistry; Islets of Langerhans; Kidney; Kidney Diseases; Male; Obesity; Pancreas; Pancreatic Diseases; Proteinuria; Rats; Rats, Zucker; Rosiglitazone; Systole; Thiazoles; Thiazolidinediones	1998
A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats. Diabetes, 1998, Volume: 47, Issue:12 Topics: Acyl-CoA Oxidase; Adipose Tissue; Animals; Blood Glucose; Body Weight; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Gene Expression; Hypoglycemic Agents; Insulin; Ligands; Lipid Metabolism; Liver; Male; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Obesity; Organ Size; Oxidoreductases; Radioligand Assay; Rats; Rats, Wistar; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Transcriptional Activation; Triglycerides	1998
The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats. Diabetes, 1999, Volume: 48, Issue:7 Topics: Acetylcholine; Animals; Blood Pressure; Endothelium, Vascular; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Vascular Resistance; Vasodilator Agents	1999
Rosiglitazone (BRL49653), a PPARgamma-selective agonist, causes peroxisome proliferator-like liver effects in obese mice. Journal of lipid research, 1999, Volume: 40, Issue:7 Topics: Animals; Electrophoresis, Gel, Two-Dimensional; Hypoglycemic Agents; Liver; Male; Mice; Mice, Obese; Obesity; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors	1999
Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes. Biochemical and biophysical research communications, 1999, Volume: 265, Issue:1 Topics: Adipocytes; Adipose Tissue; Adult; Aged; DNA-Binding Proteins; Female; Gene Expression Regulation; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Ion Channels; Leptin; Male; Membrane Transport Proteins; Middle Aged; Mitochondrial Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Obesity; Phosphatidylinositol 3-Kinases; Proteins; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness; Transcription Factors; Transcription, Genetic; Uncoupling Protein 2	1999
Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution. British journal of pharmacology, 1999, Volume: 128, Issue:7 Topics: Animals; Body Weight; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Hemodilution; Hemodynamics; Hypoglycemic Agents; Insulin; Leptin; Male; Obesity; Rats; Rats, Wistar; Rosiglitazone; Thiazoles; Thiazolidinediones	1999
Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and zucker diabetic fatty rats and effects of rosiglitazone. Brain research. Molecular brain research, 2000, Apr-14, Volume: 77, Issue:1 Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hyperglycemia; Hypoglycemic Agents; Hypothalamus; Insulin; Intracellular Signaling Peptides and Proteins; Leptin; Neuropeptides; Obesity; Orexins; Protein Precursors; Rats; Rats, Zucker; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness; Transcription, Genetic	2000
v- and t-SNARE protein expression in models of insulin resistance: normalization of glycemia by rosiglitazone treatment corrects overexpression of cellubrevin, vesicle-associated membrane protein-2, and syntaxin 4 in skeletal muscle of Zucker diabetic fat Diabetes, 2000, Volume: 49, Issue:4 Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression; Glucose Transporter Type 4; Hypoglycemic Agents; Immunoblotting; Insulin Resistance; Male; Membrane Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Qa-SNARE Proteins; R-SNARE Proteins; Rats; Rats, Sprague-Dawley; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Vesicle-Associated Membrane Protein 3	2000
Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2000, Volume: 24, Issue:8 Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Eating; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Nicotinic Acids; Obesity; Rats; Rats, Zucker; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors	2000
Mechanisms of dysregulation of 11 beta-hydroxysteroid dehydrogenase type 1 in obese Zucker rats. The Journal of endocrinology, 2000, Volume: 167, Issue:3 Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adipose Tissue; Adrenal Glands; Adrenalectomy; Analysis of Variance; Animals; Blood Glucose; Corticosterone; Eating; Hydroxysteroid Dehydrogenases; Hypertrophy; Hypoglycemic Agents; Insulin; Liver; Male; Metformin; Obesity; Omentum; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain	2000
The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat. Metabolism: clinical and experimental, 2000, Volume: 49, Issue:12 Topics: Adipose Tissue, Brown; Animals; Body Weight; Carrier Proteins; Eating; Ion Channels; Membrane Proteins; Membrane Transport Proteins; Mitochondrial Proteins; Nicotinic Acids; Obesity; Proteins; Rats; Rats, Zucker; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Uncoupling Protein 1; Uncoupling Protein 2; Uncoupling Protein 3; Weight Gain	2000
The hormone resistin links obesity to diabetes. Nature, 2001, Jan-18, Volume: 409, Issue:6818 Topics: 3T3 Cells; Adipocytes; Amino Acid Sequence; Animals; Base Sequence; Chromosomes, Human, Pair 19; Cloning, Molecular; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet; DNA; Female; Gene Expression Regulation; Glucose Intolerance; Hormones; Hormones, Ectopic; Humans; Hypoglycemic Agents; Insulin Antagonists; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nerve Growth Factor; Neutralization Tests; Obesity; Proteins; Resistin; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones	2001
Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents. Molecular pharmacology, 2001, Volume: 59, Issue:4 Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression; Glucose Tolerance Test; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Liver; Male; Muscle, Skeletal; Nicotinic Acids; Obesity; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors	2001
Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death. Diabetes, 2001, Volume: 50, Issue:5 Topics: Aging; Animals; Blood Glucose; Body Weight; Cell Death; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Obesity; Organ Size; Pancreas; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones	2001
Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability. Diabetes, 2001, Volume: 50, Issue:5 Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypertriglyceridemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Kinetics; Lipid Mobilization; Lipoproteins, VLDL; Liver; Male; Metabolic Clearance Rate; Muscle, Skeletal; Obesity; Oxidation-Reduction; Polyethylene Glycols; Postprandial Period; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Triglycerides	2001
Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists. The Journal of biological chemistry, 2001, Jul-13, Volume: 276, Issue:28 Topics: Adipocytes; Animals; Benzophenones; Down-Regulation; Hormones, Ectopic; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine	2001
Insulin-sensitizing action of rosiglitazone is enhanced by preventing hyperphagia. Diabetes, obesity & metabolism, 2001, Volume: 3, Issue:3 Topics: Animals; Body Weight; Carrier Proteins; Eating; Food Deprivation; Hyperphagia; Hypoglycemic Agents; Hypothalamus; Insulin Resistance; Ion Channels; Leptin; Male; Mitochondrial Proteins; Neuropeptide Y; Obesity; Rats; Rats, Wistar; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Uncoupling Protein 3	2001
Diabetic KKAy mice exhibit increased hepatic PPARgamma1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones. Journal of hepatology, 2001, Volume: 35, Issue:1 Topics: Animals; Chromans; Diabetes Mellitus; Fatty Liver; Gene Expression; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Obesity; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation	2001
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes. The Journal of clinical investigation, 2001, Volume: 108, Issue:7 Topics: 3T3 Cells; Adipose Tissue; Animals; Benzhydryl Compounds; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Epoxy Compounds; Fatty Acids; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Leptin; Mice; Mice, Knockout; Nicotinic Acids; Obesity; Receptors, Adrenergic, beta-3; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors	2001
Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats. Metabolism: clinical and experimental, 2001, Volume: 50, Issue:11 Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Administration, Oral; Animals; Blood Glucose; Body Weight; Glucose; Glucose Clamp Technique; Glucose Transporter Type 1; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness	2001
Thiazolidinediones influence plasma steroids of male obese Zucker rats. Endocrinology, 2002, Volume: 143, Issue:1 Topics: Animals; Blood Glucose; Body Weight; Chromans; Glucose; Hormones; Insulin; Male; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone	2002
Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the zucker Fatty rat heart. Diabetes, 2002, Volume: 51, Issue:4 Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Heart; Heart Rate; Hypoglycemic Agents; Insulin Resistance; Myocardial Ischemia; Myocardial Reperfusion; Obesity; Organ Size; Perfusion; Rats; Rats, Zucker; Reference Values; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors	2002
Increased lipolysis and decreased leptin production by human omental as compared with subcutaneous preadipocytes. Diabetes, 2002, Volume: 51, Issue:7 Topics: Adipocytes; Adult; Aged; Body Mass Index; Cell Differentiation; Female; Glycerol; Humans; Hypoglycemic Agents; Leptin; Lipolysis; Male; Middle Aged; Norepinephrine; Obesity; Omentum; RNA, Messenger; Rosiglitazone; Skin; Thiazoles; Thiazolidinediones; Transcription, Genetic; Tumor Necrosis Factor-alpha	2002
Normalization of skeletal muscle glycogen synthesis and glycolysis in rosiglitazone-treated Zucker fatty rats: an in vivo nuclear magnetic resonance study. Diabetes, 2002, Volume: 51, Issue:7 Topics: Animals; Disease Models, Animal; Gluconeogenesis; Glycolysis; Kinetics; Magnetic Resonance Spectroscopy; Models, Biological; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Reference Values; Rosiglitazone; Thiazoles; Thiazolidinediones	2002
Combination of insulin and thiazolidinedione therapy in massively obese patients with Type 2 diabetes. Diabetic medicine : a journal of the British Diabetic Association, 2002, Volume: 19, Issue:7 Topics: Adult; Aged; Body Mass Index; Body Weight; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Edema; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Obesity; Rosiglitazone; Thiazoles; Thiazolidinediones	2002