Compounds > rosiglitazone
Page last updated: 2024-08-25

rosiglitazone and Disease Models, Animal

rosiglitazone has been researched along with Disease Models, Animal in 374 studies

*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]

Research

Studies (374)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (0.80)18.2507
2000's143 (38.24)29.6817
2010's198 (52.94)24.3611
2020's30 (8.02)2.80

Authors

AuthorsStudies
Cantello, BC; Cawthorne, MA; Cottam, GP; Duff, PT; Haigh, D; Hindley, RM; Lister, CA; Smith, SA; Thurlby, PL1
Adams, AD; Berger, JP; Doebber, TW; Hu, Z; Jones, AB; MacNaul, KL; Moller, DE; Santini, C; Yuen, W1
Berger, JP; Bergman, JP; Boueres, JK; Doebber, TW; Gratale, DF; Han, W; Heck, JV; Koyama, H; Leung, K; MacNaul, KL; Metzger, EJ; Miller, DJ; Moller, DE; Sahoo, SP; Tolman, RL1
Berger, JP; Bergman, JP; Desai, RC; Doebber, TW; Gratale, DF; Han, W; Heck, JV; Leung, K; MacNaul, KL; Metzger, EJ; Moller, DE; Sahoo, SP1
Chung, SS; Hu, W; Ko, BC; Li, Z; Liao, C; Lu, XP; Ning, ZQ; Pan, D; Shan, S; Shi, L; Tong, EH; Wong, VK; Yin, Z; Zhou, J1
Agejas, J; Alt, CA; Ardecky, R; Briere, DA; Brooks, DA; Brozinick, JT; Dolores Martín-Ortega, M; Ferritto, R; Fraser, JD; González, R; Hawkins, E; Lamas, C; López de Uralde, B; Martín, JA; Misener, EA; Montrose-Rafizadeh, C; Parra, F; Prieto, L; Reifel-Miller, A; Rhodes, GA; Rizzo, JR; Robey, RL; Rojo, I; Torrado, A; Warshawsky, AM; Wendel, SR; Zhang, TY1
Acton, JJ; Berger, J; Black, RM; Colwell, L; Doebber, TW; Jones, AB; Macnaul, KL; Moller, DE; Wood, HB1
Akiyama, T; Berger, JP; Doebber, T; Dropinski, JF; Einstein, M; Habulihaz, B; Meinke, PT; Shi, GQ1
Broderick, CL; Canada, EJ; Clutinger, CK; Etgen, GJ; Irwin, LA; Laurila, ME; Mantlo, N; Montrose-Rafizadeh, C; Oldham, BA; Shi, Q; Wang, M; Warshawsky, AM; Winneroski, LL; Xie, C; Xu, Y; York, JS; Yumibe, NP; Zink, RW1
Bemis, JE; Boss, O; Carney, DP; Choy, W; Disch, JS; Elliott, PJ; Gagne, DJ; Galonek, H; Iffland, A; Israelian, K; Jin, L; Jirousek, MR; Lambert, PD; Lavu, S; Lynch, AV; Medvedik, O; Milne, JC; Ng, PY; Nunes, JJ; Olefsky, JM; Perni, RB; Schenk, S; Sinclair, DA; Smith, JJ; Vu, CB; Westphal, CH; Xie, R; Yang, H1
Auerbach, BJ; Bigge, CF; Casimiro-Garcia, A; Collard, WT; Davis, JA; Fakhoury, SA; Kane, CD; McConnell, P; McGregor, C; Ohren, JF; Padalino, T; Pulaski, J; Royer, LJ; Schaum, RP; Stevens, KA; Zhou, H1
Ahn, BN; Bae, MH; Chong, W; Han, T; Kim, E; Kim, EJ; Kim, JK; Kim, MK; Kim, SH; Lee, CH; Lim, JI; Moon, HS; Park, CS; Shim, HJ; Shin, CY; Shin, YA; Son, MH1
Audinot-Bouchez, V; Boutin, JA; Caignard, DH; Dacquet, C; Guillard, J; Hennuyer, N; Ktorza, A; Parmenon, C; Staels, B; Viaud-Massuard, MC1
Bahekar, R; Giri, S; Jain, M; Makadia, P; Patel, D; Patel, P; Pingali, H; Pola, S; Priyadarshini, P; Shah, M; Shah, SR; Suthar, D; Thube, B; Trivedi, C; Zaware, P1
Chen, J; Chen, L; Chen, T; Chen, Z; Ding, Y; Li, S; Lin, L; Ma, L; Peng, A; Qiu, N; Wang, G; Wei, Y; Xu, Q; Yang, J; Ye, X; Zheng, H1
Guo, S; Jiang, B; Li, J; Shi, D; Su, H; Wang, T1
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Chen, Z; Hu, C; Lu, D; Tang, YB; Tian, JY; Wu, L; Xiao, Z; Yang, Y; Ye, F; Zhang, ZY1
Alam, MM; Alam, MS; Alam, P; Ali, Y; Bano, S; Dhulap, A; Haider, S; Hamid, H; Kharbanda, C; Nazreen, S; Pasha, MA; Pillai, KK; Yar, MS1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E1
Askari, HB; Beauchamp, DA; Cheung, W; Gaul, MD; Geisler, JG; Huang, H; Kasturi, J; Liu, J; Patch, RJ; Patel, S; Player, MR; Rentzeperis, D; Towers, M; Xu, G; Zhao, BP1
Bourne, PC; Dou, X; Duerfeldt, AS; Ma, JX; Nath, D; Nurmemmedov, E; Shin, H1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Gu, YH; Hou, DL; Li, HB; Liu, K; Qi, X; Xu, QL; Zhao, X1
Andy, D; Erhardt, PW; Farris, JT; Heck, B; Heck, BE; Kim, DH; Kress, BJ; Mayo, JR; Sarver, JG; Trendel, JA1
Acherjee, T; Ballabh, P; Cheng, B; Deo, A; Iacobas, DA; Krishna, S; Mamtani, S; Shah, E; Sharma, DR; Stempinski, ES; Thomas, T; Yadav, S; Zhang, J; Zhang, X1
Chen, Z; Cui, L; Cui, S; Feng, Z; Gao, Q; Hu, L; Li, Q; Li, S; Meng, Q; Zhang, H; Zhang, X1
Cao, LL; Chen, QY; Huang, CM; Huang, XB; Li, P; Lin, JX; Lin, M; Liu, LC; Lu, J; Tu, RH; Wang, HG; Wang, JB; Wang, LQ; Xie, JW; Zhao, YJ; Zheng, CH; Zhong, Q1
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Altamirano-Lagos, MJ; Fernández-Fierro, A; Funes, SC; Gómez-Santander, F; Jara, EL; Kalergis, AM; Mackern-Oberti, JP; Pulgar-Sepúlveda, R; Rebolledo-Zelada, D; Ríos, M; Rivera-Perez, D; Roa, JC; Villarroel, A1
Barichello, T; Bogo, M; Burger, H; Constantino, L; Dal-Pizzol, F; de Quevedo, J; Dominguini, D; Gomes, LM; Kist, LW; Manfredini, A; Michels, M; Pinto, MC; Ritter, C; Silva, MC; Simioni, C; Singer, M; Steckert, A; Streck, E1
Dong, E; Li, QQ; Liao, WT; Liu, BR; Luo, H; Shen, YG; Tang, XQ; Wu, N; Yang, HS; Yang, Y; Yue, XZ; Zhang, GM1
Bartolotta, E; da Silveira, WA; Hardiman, G; Paolini, P; Renaud, L; Vazquez-Hidalgo, E1
Cai, XF; Lu, Q; Ma, YL; Zhang, SM1
Chen, N; Liu, J; Liu, Y; Wang, W; Yu, X; Zhang, L; Zhou, F; Zhou, Y; Zhu, Y1
Hang, H; Ren, SY; Song, AJ; Wang, LK; Wu, GF1
Inman, RD; Lin, A; Pritzker, KPH; Streutker, CJ; Tsui, FWL; Tsui, HW; Zhang, Z1
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Chen, N; Chen, SP; Li, DY; Liu, DQ; Sun, J; Tian, YK; Wang, XM; Ye, DW; Zhou, YQ1
Chen, H; Deng, J; Shao, X; Wang, X; Xia, Y; Xiong, C; Zhou, Q; Zou, H1
Chitkara, D; K C, S; Kakoty, V; Marathe, S; Taliyan, R1
Chen, H; Feng, Z; Hu, L; Meng, Q; Zhang, H; Zhang, X1
Cheng, Y; Li, X; Wang, R; Xu, Y; Yang, M1
Christensen-Dalsgaard, M; Eid, J; Grønlund, RV; Hansen, HH; Jelsing, J; Madsen, MR; Madsen, MSA; Mikkelsen, M; Rigbolt, K; Sommer, M; Vrang, N1
Chen, M; Chen, Q; Liu, Q; Min, Q; Yu, X; Zhang, S; Zhuang, L1
Gerzanich, V; Ivanova, S; Keledjian, K; Kim, K; Moyer, M; Negoita, S; Semick, S; Simard, JM; Tsymbalyuk, O1
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Cortez, I; Dineley, KT; Hernandez, CM1
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Luo, X; Wu, G; Wu, J1
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Ding, S; Wang, X; Wen, F; Xu, Z; Yang, J; Zhuge, Q; Zhuge, W1
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Jiao, Y; Ren, S; Tang, Z; Wang, L; Wu, G; Wu, J; Zhou, H1
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Adeyi, OA; Echeverri, J; Farrokhi, K; Ganesh, S; Hamar, M; Kaths, JM; Kollmann, D; Linares, I; Selzner, M; Selzner, N; Urbanellis, P; Yip, P1
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Chen, YX; Sun, R; Wang, WD1
Chen, J; Liu, H; Zhang, X1
Cui, X; Guo, J; Li, S; Li, Y; Ma, X; Nie, S; Zhi, H1
Cui, MM; Dai, CX; Ding, X; Fu, YY; Guo, MY; Li, M; Li, ZL; Qi, DS; Song, YJ; Wang, CL; Wang, YL; Wen, XR; Zhao, XF1
Alvarez, L; Corcionivoschi, N; Friedmacher, F; Gosemann, JH; Hofmann, A; Kuebler, JF; Lacher, M; Puri, P; Rittinghausen, S; Suttkus, A; Zimmer, J1
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Haeberle, HA; Henes, J; Husung, S; König, T; Mirakaj, V; Mutz, C; Nöldge-Schomburg, G; Rosenberger, P; Vagts, D1
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Chaudhary, T; Kumar, A; Mishra, J1
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An, JY; Cheng, MF; Li, DD; Luo, XH; Song, JN; Sun, P; Zhao, YL1
Li, X; Wang, Y; Wei, L; Xu, B1
Deng, YQ; Jin, DC; Song, JZ; Sun, J1
Ahn, S; Aryal, DK; Cawley, NX; Cheng, Y; Lecka-Czernik, B; Loh, YP; Murthy, SR; Rodriguiz, RM; Senatorov, V; Thouennon, E; Wetsel, WC1
Abdel-Rahman, E; Ahuja, M; Amin, AT; Amin, RH; Bagasrawala, I; Dhanasekaran, M; Kariharan, T; Nanayakkara, G; Parameshwaran, K; Suppiramaniam, V1
Czechowska, G; Dudka, J; Korolczuk, A; Maciejewski, M; Smolen, A; Widelska, I1
Dong, S; Duan, J; Fan, D; Lei, L; Li, J; Liang, Q; Liu, J; Zhang, J1
Fan, YZ; Guo, ZG; Lai, WY; Li, C; Liu, TR; Tu, Y; Xie, D; Zhong, JK1
Feng, W; Han, D; Li, MX; Li, SJ; Liu, L; Liu, Y; Lu, JM; Sun, XZ; Wang, GZ; Wu, YY; Xie, XM; Xu, J; Zhang, DX; Zhang, YH; Zhu, YT1
Liu, ZJ; Shao, ZQ1
Chen, M; Feng, T; Han, X; Li, N; Li, Y; Liu, C; Liu, P; Si, S; Wang, X; Xu, Y; Zhu, N1
Ennis, WJ; Fang, MM; Koh, TJ; Mirza, RE; Novak, ML; Sui, A; Urao, N1
Han, D; Hou, G; Kang, J; Wang, QY; Yin, Y1
Carta, AR; Casu, MA; Diana, A; Lecca, D; Mulas, G; Nevin, DK; Rossi, D; Sacchetti, G1
Jiao, Y; Wang, F; Wang, L; Wu, G; Wu, J; Zhang, Y1
Wu, J; Yang, X; Yu, XQ; Zhang, YF; Zou, XL1
Abduljawad, SH; El-Brairy, AI; El-Naa, MM; El-Readi, MZ; El-Refaei, MF; Nasif, WA1
Deng, J; Yu, J1
Ji, K; Wang, H; Wang, R; Wu, X; Yan, Z; Zang, B1
Abadie, KV; Bader, DA; Bajaj, M; Chan, L; Hamilton, MP; Hartig, SM; Long, W; Mancini, MA; McGuire, SE; Moore, DD; Motamed, M; Mueller, M; Trauner, M; Wagner, M; York, B1
Cui, Y; Deng, M; Qi, ZG; Shang, X; Wang, XL; Xie, ML; Xue, J; Zhang, Y; Zhao, X1
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Changotra, H; Mehta, V; Patel, SS; Udayabanu, M1
Beckett, E; Cardoso, RC; Chazenbalk, G; Dumesic, D; Keller, E; Madrigal, V; Moeller, J; Padmanabhan, V; Pease, A; Veiga-Lopez, A1
Arenas-Hernandez, M; Bhatti, G; Drewlo, S; Gomez-Lopez, N; Hassan, SS; Mi, QS; Milovic, T; Panaitescu, B; Plazyo, O; Romero, R; St Louis, D; Tarca, AL; Xu, Y; Xu, Z1
Kang, JY; Kim, YK; Kwon, SS; Lee, HY; Lee, SY; Park, CK; Rhee, CK; Yoon, HK1
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Drewlo, S; Garcia-Flores, V; Gomez-Lopez, N; Hassan, SS; Kadam, L; Mial, TN; Miller, D; Plazyo, O; Romero, R; Tarca, AL; Xu, Y; Xu, Z1
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Chandrasekaran, S; Khan, AA; Krishnan, UM; Kulkarni, NM; Mahat, MY; Malampati, S; Narayanan, S; Raghul, J1
Bhoi, B; Gatne, MM; Giri, SR; Jain, MR1
Burns, A; Cardoso, RC; Moeller, J; Padmanabhan, V; Skinner, DC1
Brunt, JJ; Cai, EP; Krishnamurthy, M; Luk, CT; Schroer, SA; Shi, SY; Sivasubramaniyam, T; Winer, DA; Woo, M1
Darrah, L; Ondrey, FG; Wudel, J; Wuertz, BR1
Chernichovski, T; Filip, I; Ingbir, M; Levin-Iaina, N; Levo, Y; Reshef, R; Rozovski, U; Schwartz, D; Schwartz, IF; Shtabsky, A1
Abe, M; Ichimaru, S; Kaji, S; Takiguchi, Y; Tsuchiya, K; Wada, K1
Jeon, EJ; Kim, DH; Lee, SK; Park, CS; Park, YS; Yum, JH1
Gaikwad, AB; Pathan, AR; Ramarao, P; Viswanad, B1
Hirschberg, DL; Huang, M; Li, Z; Nestorova, G; Quertermous, T; Tsao, P; Wagner, R; Wilson, KD; Wu, JC; Yock, PG; Yue, P1
Brosius, FC; Byun, J; Feldman, EL; Kennedy, RT; Kretzler, M; Lorenz, M; Pennathur, S; Saha, J; Schin, M; Zhang, H1
Aguila, MB; D'Oliveira Silva, G; de Carvalho, JJ; Mandarim-De-Lacerda, CA; Torres, TS1
Hennig, B; MacDonald, R; Oesterling, E; Shen, H; Stromberg, A; Toborek, M1
Chen, HS; Juan, CC; Lin, HD; Wu, TE1
Chen, HH; Duquette, PM; Harper, ME; Lewandowski, AJ; Qin, Z; Rai, PS; Schock, SC; Seifert, EL; Thompson, CS; Xu, J1
Distrutti, E; Fiorucci, S; Mencarelli, A; Renga, B1
Aronowski, J; Gonzales, N; Grotta, J; Zhao, X1
Gonzalez, FJ; Jia, Z; Symons, JD; Wang, N; Yang, T; Zhang, H1
Hong, TP; Liu, GQ; Liu, Z; Wang, HN; Wang, YR; Wei, XL; Wu, PX1
Aprahamian, T; Bonegio, RG; Chiang, LK; Richez, C; Rifkin, IR; Sato, K; Walsh, K; Yasuda, K1
Behar, A; Charnaux, N; Cohen-Boulakia, F; Cosson, E; Dabiré, H; Léger, G; Lestrade, R; Tarhzaoui, K; Valensi, P1
Averbukh, Z; Berman, S; Chachashvili, A; Cohen, N; Efrati, S; Siman-Tov, Y; Weissgarten, J1
Ecelbarger, CM; Hu, J; Hu, X; Riazi, S; Tiwari, S; Wang, X1
Glover, PH; Jones, AV; Maric, C; McLemore, GR; Racusen, LC; Reckelhoff, JF; Ryan, MJ; Sartori-Valinotti, JC; Venegas-Pont, M1
Cho, HJ; Hur, J; Kang, HJ; Kim, HS; Kim, SH; Kim, TY; Kwon, YW; Lee, CS; Park, KW; Park, YB; Yang, HM1
Berger, JP; Berthiaume, M; Deshaies, Y; Festuccia, WT; Laplante, M; Thieringer, R1
Chen, K; Chen, Y; Li, XC; Wang, YX; Yao, XM; Ye, SD; Zai, ZM1
Chen, C; Chen, XY; Ding, YM; Wang, B; Wang, WX; Xu, S; Yu, KH1
Caboni, P; Carboni, E; Carta, AR; Frau, L; Garau, A; Ibba, M; Schintu, N1
Allahtavakoli, M; Arababadi, MK; Javanmardi, K; Moloudi, R; Shamsizadeh, A1
Gu, J; Li, C; Li, Y; Meng, D; Miao, Z; Wang, B; Wang, CY; Wang, J; Wang, L; Xing, X; Yan, S; Yuan, Y; Zhang, S1
Debiais, F1
Jaggi, AS; Jain, V; Singh, N1
Bajwa, PJ; Lee, JW; Lytle, C; Straus, DS1
Gou, W; Ji, Y; Liu, J; Liu, N; Wang, Z1
Chae, YN; Choi, SH; Kim, HS; Kim, JG; Kim, JK; Kim, MK; Kim, SH; Lee, CH; Lim, JI; Moon, HS; Park, SK; Shin, CY; Shin, YA; Son, MH1
Akabori, H; Endo, Y; Maeda, K; Shimizu, T; Shimomura, I; Tani, T; Tsuchihashi, H; Uji, Y; Yamamoto, H1
Armstrong, M; de Langhe, S; Dill, E; Gelfand, EW; Irwin, D; Klemm, D; Koster, M; Majka, SM; Nozik-Grayck, E; Okamoto, M; Reisdorf, N; Stenmark, KR; Takeda, K; West, J; Wilder, J1
Cockerill, GW; Deb, R; Dunkley, M; Gaze, D; Gnaneswaran, Y; Howe, F; Jones, A; Loftus, IM; Nasr, H; Thompson, MM; Torsney, E1
Bland, JM; Hart, CM; Kleinhenz, DJ; Mitchell, PO; Nisbet, RE; Sutliff, RL; Walp, ER1
Bowsman, M; Chen, M; Cordover, D; Fordstrom, P; Hale, C; Helmering, J; Kaufman, SA; Lloyd, DJ; Véniant, MM; Wang, M; Zhou, M1
Brûlé, S; Chewchuk, S; Houde, V; Lavigne, C; Liu, Y; Marette, A; Pilon, G; Sweeney, G; Xu, A1
Ding, X; He, C; Noor, R; Pegg, C; Shuaib, A; Wang, CX1
Chen, C; Feng, JR; Hao, SX; Wang, WX; Yan, H1
Inestrosa, NC; Toledo, EM1
Chae, HJ; Choe, YH; Kim, SR; Lee, KS; Lee, YC; Min, KH; Moon, H; Park, SJ; Yoo, WH1
Chapman, AC; Cipolla, MJ; Roberts, TJ1
Ihm, SH; Kang, JG; Kim, SW; Lee, WY; Oh, KW; Park, CY; Park, H; Park, SW; Rhee, EJ; Won, JC; Yoo, HJ1
Hong, JH; Hwang, EY; Jeong, YJ; Kim, HJ; Lee, IS1
Al-Rasheed, NM; Eissa Ahmed, AA1
Chan, JY; Chan, SH; Chang, AY; Ho, YH; Wu, CA; Wu, KL1
Cheng, L; Han, X; Shi, Y1
Cipriani, S; Fiorucci, S; Mencarelli, A; Palladino, G1
Finck, BN; Gropler, RJ; Herrero, P; Schechtman, KB; Sharp, T; Shoghi, KI; Welch, MJ1
Aksakal, O; Gungor, T; Inan, I; Kalyoncu, S; Mollamahmutoglu, L; Sirvan, L; Sut, N; Yilmaz, B1
Cheng, Y; Liang, H; Sun, GM; Sun, L; Xu, YW1
Abdel-Aleem, OS; Badr, MZ; Donahue, RR; McNamara, KC; Morgenweck, J; Taylor, BK1
Baek, SH; Chang, K; Ihm, SH; Kim, HY; Kim, JH; Seung, KB; Youn, HJ1
Chen, HO; Fu, A; Xie, YT1
Amiri, F; Ebrahimian, T; Iglarz, M; Javeshgani, D; Lemarié, CA; Paradis, P; Savoia, C; Schiffrin, EL1
Li, LJ; Xu, RL1
Sigmund, CD1
Bae, EH; Kim, IJ; Kim, SW; Ma, SK1
Barrett, KE; Dennis, EA; Dong, H; Dumlao, DS; Glass, CK; Harmon, GS; Ng, DT1
Hu, Z; Lin, Y; Perez-Polo, JR; Ye, Y; Zhang, C1
Gulbins, E1
Arora, MK; Balakumar, P; Reddy, K1
Kaur, T; Pal Singh, A; Singh Bedi, PM; Singh, N; SinghDahiya, R1
Chan, JY; Chan, SH; Kung, PS; Wu, KL1
Ghabaei, M; Nategh, M; Parviz, M; Sadr, SSh; Shabanzadeh, AP; Shaveisi, K1
Khanduja, KL; Malhotra, S; Pandhi, P; Sidhu, S; Vaiphei, K1
Guo, X; Karathanasis, SK; Kassab, GS; Lu, X; Onyia, JE; Peterson, RG; Zimmerman, KM1
Dai, B; Fu, L; Hua, Z; Liu, Y; Mei, C; Shen, X; Xiong, X; Zhang, Y1
Huang, Y; Tian, J; Tian, XY; Wang, N; Wong, WT; Zhang, P1
Fatehi-Hassanabad, Z; Tasker, RA1
Kim, EK; Lee, JH; Lee, SD; Lee, YS; Oh, YM1
Chan, LY; Cheng, AS; Lai, KN; Lan, HY; Leung, JC; Tang, SC1
Chang, CH; Chang, SL; Cheng, JT; Lee, YC; Lin, JG; Pai, HC; Tzeng, CY1
Choi, JE; Choi, JM; Kim, DH; Kim, SW; Lee, WJ; Park, JS; Yoon, SY1
Alessi, A; Baroncini, LA; Brofman, PR; França Neto, OR; Noronha, Ld; Précoma, DB; Prim, C; Silva, RF1
Blankenship, DA; Gamboa, J; Hilow, E; Karl, M; Landreth, GE; Niemi, JP; Sundararajan, S1
Denner, L; Dineley, KT; Rodriguez-Rivera, J1
Kaplan, FS; Pignolo, RJ; Shore, EM1
Byun, K; Choi, JH; Hwang, IK; Kim, YM; Lee, B; Lee, CH; Park, OK; Won, MH; Yoo, KY1
Clemenz, M; Foryst-Ludwig, A; Hartge, M; Hess, K; Kintscher, U; Marx, N; Sprang, C; Unger, T1
Bruin, JE; Gerstein, HC; Holloway, AC; Hyslop, JR; Petrik, JJ; Raha, S; Tarnopolsky, MA1
Chen, Q; Liu, B; Liu, S; Wu, HJ; Wu, JP; Zhang, ZQ; Zhu, L1
Liu, Q; Niu, YJ; Tao, RY; Tian, JY; Ye, F; Zhu, HB; Zhu, P1
Huang, C; Shi, Q; Tang, T; Yang, H; Zhang, Q1
Li, Y; Liu, N; Ren, L; Sheng, Z; Tang, R; Zhi, H1
Braconi, S; Cannella, N; Ciccocioppo, R; Cippitelli, A; Demopulos, G; Gaitanaris, G; Heilig, M; Kallupi, M; Massi, M; Ruggeri, B; Somaini, L; Stopponi, S1
Bok, SM; Chung, MJ; Han, YM; Jin, GY; Kim, SR; Lee, YC; Yoon, KH1
Abassi, Z; Diblasio-Smith, EA; Feuerstein, GZ; Goltsman, I; Hoffman, A; Lavallie, ER; Ovcharenko, E; Wang, X; Winaver, J1
Cheng, HL; Huang, RQ; Shi, JX; Tang, K; Wu, Y; Yin, HX; Zhuang, Z1
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Lynch, M; O'Reilly, JA1
Li, J; Morrison, A; Tong, C; Yan, X1
Bastacky, S; Bilan, VP; Jones, HB; Mayers, RM; Poucher, SM; Salah, EM; Tofovic, SP; Zinker, B1
Barañao, RI; Bilotas, M; Meresman, G; Olivares, C; Ricci, A1
Minhu, C; Yao, J; Zhi, M1
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Llorens, S; Mendizábal, Y; Nava, E1
Fang, CQ; Gao, CY; Gao, D; Li, JC; Wang, JZ; Wang, YJ; Xiang, J; Yao, GE; Zhang, LL1
Banks, AS; Bruning, JB; Busby, SA; Cameron, MD; Chalmers, MJ; Choi, JH; Griffin, PR; He, Y; Jurczak, MJ; Kamenecka, TM; Kumar, N; Kuruvilla, DS; Laznik, D; Marciano, DP; Schürer, SC; Shin, Y; Shulman, GI; Spiegelman, BM; Vidović, D1
Chern, Y; Chiang, MC; Huang, RN1
GuiLian, Z; HaiQin, W; Hong, S; HuQing, W; Li, Y; Ru, Z; ShuQin, Z; Xin, Y; Yun, D1
Aroeira, LS; González-Mateo, GT; López-Cabrera, M; Ortiz, A; Ruiz-Ortega, M; Selgas, R1
Abbasi, A; Lee, WN; Rehan, VK; Sakurai, R; Torday, JS; Truong, NC1
Karbalay-Doust, S; Noorafshan, A; Omidi, A; Shariat, K1
Wang, X1
Cho, HJ; Choi, YE; Kim, BK; Kim, HS; Kwon, YW; Lee, HC; Lee, SW; Muller, DN; Park, JB; Park, KW; Yang, HM; Youn, SW1
Alves, CF; Carregaro, V; Cheraim, AB; Cunha, FQ; da Silva, CA; de Oliveira, JR; Farnesi-de-Assunção, TS; Napimoga, MH1
Gao, W; Jusko, WJ1
Martin, HL; Mounsey, RB; Mustafa, S; Sathe, K; Teismann, P1
Dai, W; Gao, X; Jin, H; Liu, S; Mei, C; Yan, S; Zhang, W; Zhang, Y1
Araújo, CV; Bozza, PT; Castro-Faria-Neto, HC; Estato, V; Silva, AR; Tibiriçá, E1
Gupta-Rajoria, R; Jadhav, R; Pal, T; Subramanian, RC1
Li, D; Liu, JH; Wang, GL; Wang, L; Wu, LN; Zhu, DZ1
Bi, F; Huang, B; Huang, C; Tong, J; Wu, Q; Xia, XG; Zhou, H1
Koh, HC; Lee, EY; Lee, JE; Park, JH; Shin, IC1
Bhandari, S; Semple, DJ; Seymour, AM1
Jang, KY; Jeon, SY; Kim, HS; Kwak, JY; Lee, NR; Park, HS; Rho, HW; Sohn, MH; Song, EK; Song, MY; Yhim, HY; Yim, CY; Yim, JM; Yim, JY; Yim, SK1
Akbari, O; Kwong, K; Liu, J; Lombardi, V; Naeem, E; Rehan, VK; Tian, J; Torday, JS1
Chan, PH; Jung, JE; Kim, GS; Maier, CM; Narasimhan, P; Okami, N; Sakata, H; Yoshioka, H1
Fan, B; Li, G; Liang, S; Liu, S; Peng, H; Qin, S; Qiu, S; Tu, G; Xu, H; Xu, W; Yu, S; Zheng, C; Zhu, Q; Zhu, S1
Belgorosky, D; Eiján, AM; Langle, Y; Lodillinsky, C; Sandes, EO1
Brookes, ZL; Huang, L; Nauli, SM; Ong, AC; Prasad, S; Ruff, L; Solanky, T; Upadhyay, VS1
Christensen, LP; Kristiansen, K; Rimbach, G; Schrader, E; Wein, S; Wolffram, S1
Jyothi Kumari, P; Lakshmi, BS; Sangeetha, KN; Shilpa, K1
Albertz, J; Duan, W; Guo, Z; Jin, J; Peng, Q; Ross, CA; Rudow, G; Troncoso, JC1
Gao, XQ; Gao, Y; Li, HW; Ling, X; Qiu, YH; Zhang, Y1
Celinski, K; Dworzanski, T; Fornal, R; Korolczuk, A; Madro, A; Slomka, M1
Banday, AA; Hussain, T; Lokhandwala, MF; Umrani, DN1
Aburatani, H; Blumberg, RS; Kadowaki, T; Matsuhashi, N; Nagai, R; Nakajima, A; Saubermann, LJ; Terauchi, Y; Wada, K; Zhao, S1
Kazdová, L; Kren, V; Krenová, D; Seda, O1
Anglard, P; Bonnafous, S; Chavey, C; Mari, B; Monthouel, MN; Tartare-Deckert, S; Van Obberghen, E1
Ida, M; Kurosaki, E; Nakano, R; Shibasaki, M; Shikama, H; Shimaya, A; Suzuki, T; Yoshida, S1
Auwerx, J; Capron, M; Dombrowicz, D; Honda, K; Loyens, M; Papin, JP; Staels, B; Woerly, G1
Barringhaus, KG; Chen, M; Czarnik, AC; Hesselbacher, S; Ley, K; Nadler, J; Phillips, JW; Sanders, JM; Sarembock, IJ; Yang, Z1
Bagi, Z; Kaley, G; Koller, A1
Bosco, AA; Lerario, AC; Santos, RF; Wajchenberg, BL1
Batinic-Haberle, I; Christopher, TA; Gao, E; Liu, HR; Lopez, BL; Ma, XL; Ohlstein, EH; Tao, L; Teng, ZP; Willette, RN; Yue, TL1
Marescaux, J; Rubino, F1
Angeli, V; de Heer, HJ; Hammad, H; Hoogsteden, HC; Lambrecht, BN; Soullié, T; Trottein, F1
Desouza, CV; Diez, J; Dunne, B; Fonseca, VA; Matta, AS; McNamara, DB; Murthy, SN1
Baker, DL; Balazs, L; Bittman, R; Byun, HS; Johnson, LR; Makarova, N; Marathe, GK; McIntyre, TM; Prestwich, GD; Tigyi, G; Xu, Y; Yasuda, S; Zhang, C1
Béréziat, V; Burnol, AF; Capitaine, N; Cariou, B; Girard, J; Kergoat, M; Laville, M; Le Marcis, V; Vega, N; Vidal, H1
Adeli, K; Leung, N; Lewis, GF; Naples, M; Szeto, L; Uffelman, K1
Belvisi, MG; Birrell, MA; Leonard, T; McCluskie, K; Patel, HJ; Wong, S; Yacoub, MH1
Flynn, ER; Pedersen, WA1
Gavrilova, O; Haluzik, M; Kim, H; LeRoith, D; Pajvani, UB; Portas, J; Scherer, PE; Sun, H; Yakar, S1
Atkinson, RD; Lee, JW; Lytle, C; Straus, DS; Tod, TJ; Vo, KT1
Chai, OH; Hwang, PH; Kim, JS; Lee, KS; Lee, MK; Lee, YC; Park, SJ; Song, CH; Yi, HK1
Kang, KP; Kim, DH; Kim, HJ; Kim, W; Lee, S; Moon, SO; Park, SK; Sung, MJ1
Leiter, EH; Pan, HJ; Reifsnyder, P; Vance, DE; Xiao, Q1
Fiévet, C; Fruchart, JC; Hennuyer, N; Mezdour, H; Staels, B; Tailleux, A; Torpier, G1
Allen, TJ; Calkin, AC; Cooper, ME; Forbes, JM; Jandeleit-Dahm, KA; Lassila, M; Smith, CM1
Boscá, L; Cárdenas, A; Castillo, J; Dávalos, A; Hurtado, O; Lizasoain, I; Lorenzo, P; Moro, MA; Pereira, MP; Serena, J; Vivancos, J1
Graham, TE; Kahn, BB; Kotani, K; Mody, N; Peroni, OD; Preitner, F; Quadro, L; Yang, Q; Zabolotny, JM1
Hunt, MJ; Morton, AJ1
Jin, SM; Kim, SR; Lee, KS; Lee, YC; Min, KH; Park, HS; Park, SJ1
Leiter, EH; Mistry, J; Pan, HJ; Reifsnyder, PC; Xiao, Q; Zhang, W1
Bonacci, JV; Fernandes, DJ; Quan, L; Stewart, AG; Taylor, CC; Ward, JE1
Adler, S; Banz, WJ; Davis, J; Henry, N; Higginbotham, DA; Hou, Y; Meyers, CY; Oitker, J; Peterson, R; Steinle, JJ; Winters, TA1
Aytan, H; Aytan, P; Caliskan, AC; Demirturk, F; Koseoglu, DR2
Laverty, R; Ledingham, JM1
Averbukh, Z; Berman, S; Efrati, S; Feldman, L; Rapoport, M; Weissgarten, J1
Craft, S; Haynatzki, GR; Kulstad, JJ; Leverenz, JB; McMillan, PJ; Pedersen, WA1
Chen, J; Graham, SH; Hong, Z; Luo, Y; Signore, AP; Wang, S; Yin, W; Zhang, F1
Cuzzocrea, S1
Kurosaki, E; Maruyama, T; Nakano, R; Shibasaki, M; Shimaya, A; Yokono, M; Yoshida, S1
Allen, TJ; Calkin, AC; Cooper, ME; Giunti, S; Jandeleit-Dahm, KA; Thomas, MC1
Landreth, G1
Chen, YE; Leiter, EH; Lin, Y; Pan, HJ; Vance, DE1
Chen, YT; Li, PP; Liu, Q; Lu, XP; Ning, ZQ; Shan, S; Shen, ZF; Sun, SJ; Xie, MZ1
Chen, WK; Wang, T; Zhang, DM; Zhang, GY; Zhong, HJ1
Aytan, H; Aytan, P; Caliskan, A; Demirturk, F; Koseoglu, D; Yener, T; Yenisehirli, A1
Franck, N; Kjølhede, P; Nystrom, FH; Paulsson, JF; Sauma, L; Söderström, M; Strålfors, P; Westermark, GT1
Fernández, PL1
Avni, I; Grossman, E; Kamari, Y; Oron-Herman, M; Peleg, E; Shabtay, Z; Shamiss, A; Sharabi, Y1
Belury, MA; Liu, LF; Purushotham, A; Wendel, AA1
Hansmann, G; Perez, VA; Rabinovitch, M; Schellong, S; Sheikh, AY; Stewart, DJ; Suen, RS; Urashima, T; Wagner, RA; Wang, L1
Gaikwad, AB; Ramarao, P; Viswanad, B1
Bowen, KK; Feinstein, DL; Kapadia, R; Liang, J; Satriotomo, I; Tureyen, K; Vemuganti, R1
Caelles, C; Díaz-Delfín, J; Morales, M1
Asano, S; Hansen, MK; Higashiyama, H; Kinoshita, M; McVey, MJ; Okamoto, Y; Rong, JX1
Avsar, E; Celikel, C; Emekli, E; Eren, F; Haklar, G; Imeryuz, N; Tahan, V; Tozun, N; Uzun, H; Yavuz, D; Yuksel, M1
Bonen, A; Chen, ZP; Febbraio, MA; Hawley, JA; Kemp, BE; Lessard, SJ; Reeder, DW; Rivas, DA; Yaspelkis, BB1
Asano, S; Hansen, MK; Higashiyama, H; Mattie, MD; Okamoto, Y; Qiu, Y; Rong, JX; Ryan, TE; Strum, JC; Xie, M; Zhang, V; Zhu, L1
Cho, BP; Chung, CH; Koh, JH; Lee, BJ; Lee, EY; Lee, MY; Shin, JY; Shin, YG; Won, CS1
Ahn, KO; Choi, BS; Ito, S; Kim, J; Kim, YS; Li, C; Lim, SW; Sugawara, A; Yang, CW; Yang, HJ1
Mensink, RP; Plat, J; Ramakers, JD; Te Velde, AA; Thuijls, G; Verstege, MI1
Balakumar, P; Rose, M; Singh, M1
Arhancet, GB; Blanner, PM; Bolten, CW; Chott, RC; Colca, JR; Ghosh, S; Gulve, EA; Hromockyj, AE; McDonald, WG; Payne, MA; Staten, NR; Sullivan, PM1
Hart, CM; Holguin, F; Rojas, M1
Chan, L; Chow, WS; Fong, CH; Hoo, RL; Lam, KS; Tam, S; Tse, HF; Tso, AW; Xu, A; Yau, MH1
Avsar, E; Celikel, C; Imeryuz, N; Tahan, V; Tozun, N1
den Ouden, K; Goldschmeding, R; Joles, JA; Nguyen, TQ; Verhaar, MC; Westerweel, PE1
Chin-Dusting, J; Cooper, ME; Jandeleit-Dahm, KA; Kling, D; Mizrahi, J; Murphy, A; Sebokova, E; Sheehy, K; Tikellis, C; Woollard, KJ1
Baik, SH; Bak, YT; Byun, KS; Choi, KM; Jo, NY; Kim, A; Kim, JH; Kim, JS; Lee, CH; Park, JJ; Seo, YS; Yeon, JE1
Chicco, A; Greyson, CR; Lu, L; Reiter, MJ; Schwartz, GG; Xu, Y1
Deng, YC; Huang, YG; Li, YN; Shao, XG; Sun, H; Yang, J; Yu, X1
Abram, SR; Carter, C; Dearman, J; Hester, RL; Xiang, L1
Christopher, TA; Gao, F; Guo, W; Ji, Q; Li, J; Li, R; Lopez, BL; Ma, H; Ma, X; Wang, H; Zhang, H; Zhang, Q1
Berger, JP; Chang, CH; Doebber, TW; McCann, ME; McNamara, LA; Meinke, PT; Muise, ES; Tan, Y; Thompson, JR; Wood, HB; Wu, MS1
Cong, WN; Liu, GT; Tao, RY; Tian, JY; Ye, F1
Li, ZJ; Song, LY; Wang, WH; Zhang, BL; Zhang, X1
Chen, H; He, YW; Liu, WQ; Zhang, JH1
Hyong, A; Jadhav, V; Lee, S; Rowe, J; Tang, J; Tong, W; Zhang, JH1
Cawthorne, MA; Coyle, PJ; Holder, JC; Holman, GD; Kirkham, DM; Kozka, IJ; Lister, CA; Smith, SA; Young, PW1
Buckingham, RE; Pickavance, LC; Tadayyon, M; Widdowson, PS; Wilding, JP1
Arioglu, E; Chao, L; Gavrilova, O; Marcus-Samuels, B; Mason, MM; Moitra, J; Reitman, ML; Vinson, C1
Collins, AR; Hsueh, WA; Kawano, Y; Nicholas, SB; Wakino, S1
Boehm, M; Crombie, DL; Davies, PJ; Depre, C; Heyman, RA; Leibowitz, MD; Liu, S; Nagy, L; Singh Ahuja, H; Tontonoz, P1
Blumberg, RS; Nakajima, A; Wada, K1
Asakawa, M; Hasegawa, H; Kadowaki, T; Komuro, I; Kubota, N; Masuda, Y; Nagai, T; Saito, T; Takano, H; Uozumi, H1
Chun, D; Cobitz, AR; Davis, HM; Haimbach, RE; Jucker, BM; Mayer, M; McIntosh, TS; Ohlstein, DH; Sarkar, SK; Schaeffer, TR; Smith, SA1

Reviews

6 review(s) available for rosiglitazone and Disease Models, Animal

ArticleYear
A systematic literature review of the effect of insulin sensitizers on the cognitive symptoms of Alzheimer's Disease in transgenic mice.
    Behavioural brain research, 2019, 10-17, Volume: 372

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cognition; Cognition Disorders; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Insulin; Insulin Resistance; Metformin; Mice; Mice, Transgenic; Phosphorylation; Pioglitazone; Rosiglitazone; tau Proteins

2019
Modulatory effects of peroxisome proliferator-activated receptor-γ on CXCR3 chemokines.
    Recent patents on inflammation & allergy drug discovery, 2014, Volume: 8, Issue:2

    Topics: Animals; Autoimmune Diseases; Chemokines; Disease Models, Animal; Europe; Humans; Immunity, Cellular; Immunomodulation; Inflammation; Patents as Topic; Pioglitazone; PPAR gamma; Receptors, CXCR3; Rosiglitazone; Th1 Cells; Thiazolidinediones

2014
Endothelial and vascular muscle PPARgamma in arterial pressure regulation: lessons from genetic interference and deficiency.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2

    Topics: Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regulation; Hypertension; Mice; Muscle, Smooth, Vascular; PPAR gamma; Rats; Rats, Zucker; Risk Assessment; Rosiglitazone; Thiazolidinediones

2010
Assessment of cardiac safety for PPARγ agonists in rodent models of heart failure: a translational medicine perspective.
    Current molecular pharmacology, 2012, Volume: 5, Issue:2

    Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Profiling; Heart Failure; Hypoglycemic Agents; Kidney; Myocardial Infarction; PPAR gamma; Rosiglitazone; Thiazolidinediones; Translational Research, Biomedical

2012
Peroxisome proliferator-activated receptors and acute lung injury.
    Current opinion in pharmacology, 2006, Volume: 6, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Humans; Ligands; PPAR alpha; PPAR gamma; Prostaglandin D2; Respiratory Distress Syndrome; Rosiglitazone; Thiazolidinediones

2006
PPARgamma agonists as new therapeutic agents for the treatment of Alzheimer's disease.
    Experimental neurology, 2006, Volume: 199, Issue:2

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; Humans; PPAR gamma; Rosiglitazone; Thiazolidinediones

2006

Trials

2 trial(s) available for rosiglitazone and Disease Models, Animal

ArticleYear
Effect of rosiglitazone on rabbit model of myocardial ischemia-reperfusion injury.
    Asian Pacific journal of tropical medicine, 2013, Volume: 6, Issue:3

    Topics: Animals; C-Reactive Protein; Creatine Kinase; Creatine Kinase, MB Form; Disease Models, Animal; Endothelins; Glutathione Peroxidase; Heart; Hypoglycemic Agents; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Rabbits; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones; Treatment Outcome

2013
Adiponectin mediates the suppressive effect of rosiglitazone on plasminogen activator inhibitor-1 production.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:12

    Topics: 3T3-L1 Cells; Adenoviridae; Adipocytes; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Fibrinolytic Agents; Genetic Vectors; Humans; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Plasminogen Activator Inhibitor 1; PPAR gamma; Recombinant Proteins; RNA, Messenger; Rosiglitazone; Serpin E2; Serpins; Sulfonylurea Compounds; Thiazolidinediones; Transduction, Genetic; Treatment Outcome

2007

Other Studies

366 other study(ies) available for rosiglitazone and Disease Models, Animal

ArticleYear
[[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents.
    Journal of medicinal chemistry, 1994, Nov-11, Volume: 37, Issue:23

    Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Hemoglobins; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Structure-Activity Relationship; Thiazoles

1994
Amphipathic 3-phenyl-7-propylbenzisoxazoles; human pPaR gamma, delta and alpha agonists.
    Bioorganic & medicinal chemistry letters, 2003, Mar-10, Volume: 13, Issue:5

    Topics: Administration, Oral; Animals; Biological Availability; COS Cells; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Isoxazoles; Mice; Mice, Mutant Strains; Nuclear Proteins; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

2003
5-Aryl thiazolidine-2,4-diones as selective PPARgamma agonists.
    Bioorganic & medicinal chemistry letters, 2003, May-19, Volume: 13, Issue:10

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Hypoglycemic Agents; Inhibitory Concentration 50; Mice; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship; Thiazolidinediones; Transcription Factors

2003
5-aryl thiazolidine-2,4-diones: discovery of PPAR dual alpha/gamma agonists as antidiabetic agents.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Administration, Oral; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Hyperglycemia; Hypertriglyceridemia; Hypoglycemic Agents; Mice; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Structure-Activity Relationship; Thiazolidinediones; Transcription Factors

2003
Design, synthesis, and evaluation of a new class of noncyclic 1,3-dicarbonyl compounds as PPARalpha selective activators.
    Bioorganic & medicinal chemistry letters, 2004, Jul-05, Volume: 14, Issue:13

    Topics: Adipose Tissue; Administration, Oral; Aldehydes; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Design; Hypolipidemic Agents; Ketones; Lipid Metabolism; Mice; PPAR alpha; PPAR delta; PPAR gamma; Structure-Activity Relationship

2004
2-Alkoxydihydrocinnamates as PPAR agonists. Activity modulation by the incorporation of phenoxy substituents.
    Bioorganic & medicinal chemistry letters, 2005, Jan-03, Volume: 15, Issue:1

    Topics: Animals; Blood Glucose; Cinnamates; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Peroxisome Proliferator-Activated Receptors; Rats; Rats, Zucker; Structure-Activity Relationship; Triglycerides

2005
Benzoyl 2-methyl indoles as selective PPARgamma modulators.
    Bioorganic & medicinal chemistry letters, 2005, Jan-17, Volume: 15, Issue:2

    Topics: Animals; Benzoates; Diabetes Mellitus; Disease Models, Animal; Humans; Indoles; Inflammation Mediators; Ligands; Molecular Structure; PPAR gamma

2005
Synthesis and biological activities of novel aryl indole-2-carboxylic acid analogs as PPARgamma partial agonists.
    Bioorganic & medicinal chemistry letters, 2005, Nov-15, Volume: 15, Issue:22

    Topics: Animals; Blood Glucose; Carboxylic Acids; Disease Models, Animal; Humans; Indoles; Inhibitory Concentration 50; Male; Mice; Molecular Structure; PPAR gamma; Structure-Activity Relationship; Titrimetry

2005
Design and synthesis of novel and potent amide linked PPARgamma/delta dual agonists.
    Bioorganic & medicinal chemistry letters, 2007, Dec-15, Volume: 17, Issue:24

    Topics: Amides; Animals; Combinatorial Chemistry Techniques; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Design; Indoles; Molecular Structure; PPAR delta; PPAR gamma; Rats

2007
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
    Nature, 2007, Nov-29, Volume: 450, Issue:7170

    Topics: Acetylation; Allosteric Site; Animals; Blood Glucose; Caloric Restriction; Catalytic Domain; Cell Line; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Drosophila melanogaster; Heterocyclic Compounds, 4 or More Rings; Humans; Insulin; Male; Mice; Mitochondria; Rats; Rats, Sprague-Dawley; Rats, Zucker; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes

2007
Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.
    Bioorganic & medicinal chemistry, 2008, May-01, Volume: 16, Issue:9

    Topics: Administration, Oral; Animals; Crystallography, X-Ray; Disease Models, Animal; Male; Mice; Mice, Obese; Models, Molecular; Molecular Structure; Phenylpropionates; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Rats, Zucker; Stereoisomerism; Structure-Activity Relationship

2008
Design, synthesis, and evaluation of novel aryl-tetrahydropyridine PPARalpha/gamma dual agonists.
    Bioorganic & medicinal chemistry letters, 2008, Sep-15, Volume: 18, Issue:18

    Topics: Animals; Combinatorial Chemistry Techniques; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Design; Mice; Molecular Structure; PPAR alpha; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley

2008
4,4-Dimethyl-1,2,3,4-tetrahydroquinoline-based PPARalpha/gamma agonists. Part. II: Synthesis and pharmacological evaluation of oxime and acidic head group structural variations.
    Bioorganic & medicinal chemistry letters, 2009, May-15, Volume: 19, Issue:10

    Topics: Animals; Cell Line; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Mice; Oximes; PPAR alpha; PPAR gamma; Quinolines; Rats; Structure-Activity Relationship

2009
Effect of structurally constrained oxime-ether linker on PPAR subtype selectivity: Discovery of a novel and potent series of PPAR-pan agonists.
    Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2

    Topics: Animals; Cricetinae; Disease Models, Animal; Ether; Hep G2 Cells; Humans; Hypoglycemic Agents; Male; Mice; Mice, Obese; Oximes; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR delta; PPAR gamma; Structure-Activity Relationship; Thiazoles

2011
Synthesis and biological activity of novel barbituric and thiobarbituric acid derivatives against non-alcoholic fatty liver disease.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adiponectin; Animals; Barbiturates; Cell Differentiation; Disease Models, Animal; Fatty Liver; Leptin; Male; Mice; Molecular Structure; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Thiobarbiturates

2011
Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties.
    Bioorganic & medicinal chemistry letters, 2012, Apr-15, Volume: 22, Issue:8

    Topics: Animals; Bromine; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Hypoglycemic Agents; Inhibitory Concentration 50; Mice; Phenols; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rhodophyta

2012
Synthesis and biological evaluation of 5-benzylidenepyrimidine-2,4,6(1H,3H,5H)-trione derivatives for the treatment of obesity-related nonalcoholic fatty liver disease.
    Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Alanine Transaminase; Animals; Barbiturates; Body Weight; Cholesterol; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Female; Glucose; Glucose Tolerance Test; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Leptin; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Piperidines; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tissue Distribution; Triglycerides

2012
Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors.
    Bioorganic & medicinal chemistry letters, 2013, Apr-15, Volume: 23, Issue:8

    Topics: Animals; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Humans; Insulin; Insulin Resistance; Mice; Models, Molecular; Molecular Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Recombinant Proteins; Structure-Activity Relationship; Sulfathiazoles

2013
Thiazolidine-2,4-diones derivatives as PPAR-γ agonists: synthesis, molecular docking, in vitro and in vivo antidiabetic activity with hepatotoxicity risk evaluation and effect on PPAR-γ gene expression.
    Bioorganic & medicinal chemistry letters, 2014, Jul-15, Volume: 24, Issue:14

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Liver; Molecular Docking Simulation; Molecular Structure; PPAR gamma; Rats; Rats, Wistar; Risk Assessment; Streptozocin; Thiazolidinediones

2014
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship

2017
Indazole-based ligands for estrogen-related receptor α as potential anti-diabetic agents.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; ERRalpha Estrogen-Related Receptor; Hypoglycemic Agents; Indazoles; Ligands; Male; Mice; Mice, Obese; Molecular Structure; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Estrogen; Structure-Activity Relationship

2017
Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Animals; Benzylamines; Capillary Permeability; Cell Line; Diabetic Retinopathy; Disease Models, Animal; Drug Design; Drug Discovery; Humans; PPAR alpha; Rats; Retinal Diseases; Streptozocin

2020
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Design, synthesis, and biological evaluation of a novel dual peroxisome proliferator-activated receptor alpha/delta agonist for the treatment of diabetic kidney disease through anti-inflammatory mechanisms.
    European journal of medicinal chemistry, 2021, Jun-05, Volume: 218

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Humans; Hypoglycemic Agents; Male; Molecular Structure; NF-kappa B; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship

2021
Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis.
    Journal of medicinal chemistry, 2021, 05-27, Volume: 64, Issue:10

    Topics: Animals; Cell Differentiation; Disease Models, Animal; Drug Design; Female; Femur; Humans; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteogenesis; Osteoporosis; PPAR delta; Structure-Activity Relationship; Thiazoles; X-Ray Microtomography

2021
PPAR-γ activation enhances myelination and neurological recovery in premature rabbits with intraventricular hemorrhage.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 09-07, Volume: 118, Issue:36

    Topics: Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Antiporters; Cerebral Intraventricular Hemorrhage; Disease Models, Animal; Hereditary Central Nervous System Demyelinating Diseases; Humans; Infant, Premature; Microglia; Mitochondrial Diseases; Myelin Proteins; Oligodendroglia; PPAR gamma; Psychomotor Disorders; Rabbits; Rosiglitazone; Sequence Analysis, RNA

2021
Rosiglitazone Ameliorates Spinal Cord Injury
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Disease Models, Animal; Humans; Hypoglycemic Agents; Inflammation; Male; Mitophagy; Neural Stem Cells; Rats; Rats, Sprague-Dawley; Rosiglitazone; Spinal Cord Injuries

2022
The peroxisome proliferator-activated receptor agonist rosiglitazone specifically represses tumour metastatic potential in chromatin inaccessibility-mediated FABP4-deficient gastric cancer.
    Theranostics, 2022, Volume: 12, Issue:4

    Topics: Animals; Chromatin; Disease Models, Animal; Fatty Acid-Binding Proteins; Humans; Hypoglycemic Agents; Mice; PPAR gamma; Rosiglitazone; Stomach Neoplasms; Thiazolidinediones

2022
Optimizing the Time Window of Minimally Invasive Stereotactic Surgery for Intracerebral Hemorrhage Evacuation Combined with Rosiglitazone Infusion Therapy in Rabbits.
    World neurosurgery, 2022, Volume: 165

    Topics: Animals; Blood-Brain Barrier; Cerebral Hemorrhage; Disease Models, Animal; Glutamic Acid; Interleukin-1beta; Interleukin-6; Minimally Invasive Surgical Procedures; Nitric Oxide Synthase; PPAR gamma; Rabbits; RNA, Messenger; Rosiglitazone; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Water

2022
Rosiglitazone Ameliorates Cardiac and Skeletal Muscle Dysfunction by Correction of Energetics in Huntington's Disease.
    Cells, 2022, 08-27, Volume: 11, Issue:17

    Topics: Animals; Disease Models, Animal; Huntington Disease; Mice; Mice, Transgenic; Muscle, Skeletal; Neurodegenerative Diseases; PPAR gamma; Rosiglitazone

2022
Tolerogenic dendritic cell transfer ameliorates systemic lupus erythematosus in mice.
    Immunology, 2019, Volume: 158, Issue:4

    Topics: Animals; Antibodies, Antinuclear; Cell Differentiation; Cells, Cultured; Dendritic Cells; Dexamethasone; Disease Models, Animal; Humans; Immune Tolerance; Immunotherapy, Adoptive; Kidney; Lupus Erythematosus, Systemic; Lymphocyte Activation; Mice; Mice, Inbred MRL lpr; Pyrazines; Pyrroles; Rosiglitazone; T-Lymphocytes, Regulatory

2019
Mitochondrial dysfunction is associated with long-term cognitive impairment in an animal sepsis model.
    Clinical science (London, England : 1979), 2019, 09-30, Volume: 133, Issue:18

    Topics: Animals; Autophagy; Brain; Cognitive Dysfunction; Disease Models, Animal; Male; Mitochondria; Mitochondrial Dynamics; Rats, Wistar; Rilmenidine; Rosiglitazone; Sepsis; Sirolimus; Survival Analysis; Up-Regulation

2019
Chronological in vivo imaging reveals endothelial inflammation prior to neutrophils accumulation and lipid deposition in HCD-fed zebrafish.
    Atherosclerosis, 2019, Volume: 290

    Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Atherosclerosis; Cholesterol, Dietary; Disease Models, Animal; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Hypercholesterolemia; Inflammation; Interleukin-1beta; Lipid Metabolism; Microscopy, Confocal; Neutrophil Infiltration; Plaque, Atherosclerotic; PPAR gamma; Rosiglitazone; Time Factors; Tumor Necrosis Factor-alpha; Zebrafish; Zebrafish Proteins

2019
The effects of rosiglitazone on the neonatal rat cardiomyocyte transcriptome: a temporal analysis.
    Pharmacogenomics, 2019, Volume: 20, Issue:16

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Heart Ventricles; Humans; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Rats; Rosiglitazone; Signal Transduction; Transcriptome

2019
Effect of rosiglitazone on myocardial injury in septic rats through NF-κB pathway.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:1

    Topics: Administration, Oral; Animals; Disease Models, Animal; Female; Hypoglycemic Agents; Myocytes, Cardiac; NF-kappa B; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sepsis; Shock, Septic; Signal Transduction; Tumor Necrosis Factor-alpha

2020
Altered Expression of Long Noncoding and Messenger RNAs in Diabetic Nephropathy following Treatment with Rosiglitazone.
    BioMed research international, 2020, Volume: 2020

    Topics: Animals; Computational Biology; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; NF-kappa B; PPAR gamma; RNA, Long Noncoding; RNA, Messenger; Rosiglitazone; Sequence Analysis, RNA; Tumor Necrosis Factor-alpha; Up-Regulation

2020
Activating PPARγ Increases NQO1 and γ-GCS Expression via Nrf2 in Thrombin-activated Microglia.
    Current medical science, 2020, Volume: 40, Issue:1

    Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebral Hemorrhage; Disease Models, Animal; Female; Glutamate-Cysteine Ligase; Isothiocyanates; Male; Microglia; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; PPAR gamma; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sulfoxides; Thrombin; Tretinoin

2020
Lipocalin 2 links inflammation and ankylosis in the clinical overlap of inflammatory bowel disease (IBD) and ankylosing spondylitis (AS).
    Arthritis research & therapy, 2020, 03-18, Volume: 22, Issue:1

    Topics: Animals; Ankylosis; Disease Models, Animal; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Lipocalin-2; Male; Mice, Knockout; PPAR gamma; Rosiglitazone; Spondylitis, Ankylosing; Up-Regulation

2020
The protective effect of PPARγ in sepsis-induced acute lung injury via inhibiting PTEN/β-catenin pathway.
    Bioscience reports, 2020, 05-29, Volume: 40, Issue:5

    Topics: Acute Lung Injury; Anilides; Animals; Apoptosis; beta Catenin; Disease Models, Animal; Lung; Male; Phosphorylation; Pneumonia; PPAR gamma; PTEN Phosphohydrolase; Pulmonary Edema; Rats, Sprague-Dawley; Rosiglitazone; Sepsis; Signal Transduction

2020
PPARγ activation mitigates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of Nrf2/HO-1 signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Analgesics; Animals; Disease Models, Animal; Heme Oxygenase (Decyclizing); Hyperalgesia; Male; Neuralgia; NF-E2-Related Factor 2; Paclitaxel; Pain Perception; Pain Threshold; PPAR gamma; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Spinal Cord; Up-Regulation

2020
Treatment with a PPAR-γ Agonist Protects Against Hyperuricemic Nephropathy in a Rat Model.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Administration, Oral; Animals; Disease Models, Animal; Hyperuricemia; Kidney Diseases; Male; Neuroprotective Agents; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone

2020
Exploring the Neuroprotective Potential of Rosiglitazone Embedded Nanocarrier System on Streptozotocin Induced Mice Model of Alzheimer's Disease.
    Neurotoxicity research, 2021, Volume: 39, Issue:2

    Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Humans; Male; Neuroprotective Agents; Rosiglitazone; Streptozocin

2021
Rosiglitazone ameliorates radiation-induced intestinal inflammation in rats by inhibiting NLRP3 inflammasome and TNF-α production.
    Journal of radiation research, 2020, Nov-16, Volume: 61, Issue:6

    Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypoglycemic Agents; In Vitro Techniques; Inflammasomes; Inflammation; Interleukin-1beta; Intestines; Macrophages; Macrophages, Peritoneal; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Radiation Injuries; Rats; Rats, Sprague-Dawley; Rosiglitazone; Tumor Necrosis Factor-alpha

2020
Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:12

    Topics: A549 Cells; Animals; Cell Death; Cell Line, Tumor; Coenzyme A Ligases; Disease Models, Animal; Epithelial Cells; Ferroptosis; Glutathione; Humans; Lipid Peroxidation; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mitochondria; Phospholipid Hydroperoxide Glutathione Peroxidase; Reperfusion Injury; Rosiglitazone

2020
Characterization of local gut microbiome and intestinal transcriptome responses to rosiglitazone treatment in diabetic db/db mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133

    Topics: Animals; Bacteria; Diabetes Mellitus; Disease Models, Animal; Gastrointestinal Microbiome; Gene Expression Regulation; Host-Pathogen Interactions; Hypoglycemic Agents; Intestines; Male; Mice; PPAR gamma; Rosiglitazone; Signal Transduction; Transcriptome

2021
Rosiglitazone affects the progression of surgically‑induced endometriosis in a rat model.
    Molecular medicine reports, 2021, Volume: 23, Issue:1

    Topics: Animals; Caspase 3; Disease Models, Animal; Disease Progression; Endometriosis; Female; Gene Expression Regulation; Gynecologic Surgical Procedures; Methionine Adenosyltransferase; PPAR gamma; Rats; Rosiglitazone; Treatment Outcome; Vascular Endothelial Growth Factor A

2021
The peroxisome proliferator-activated receptor gamma (PPARγ) agonist, rosiglitazone, ameliorates neurofunctional and neuroinflammatory abnormalities in a rat model of Gulf War Illness.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Animals; Anxiety; Astrocytes; Brain; Cognition; Disease Models, Animal; Female; Hippocampus; Lipopolysaccharides; Male; Persian Gulf Syndrome; PPAR gamma; Pyridostigmine Bromide; Rats; Rats, Wistar; Rosiglitazone; Stress, Psychological

2020
Pathological changes of frozen shoulder in rat model and the therapeutic effect of PPAR-γ agonist.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2021, Volume: 39, Issue:4

    Topics: Animals; Biomechanical Phenomena; Bursitis; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Inflammation; PPAR gamma; Range of Motion, Articular; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Rosiglitazone

2021
Enhancement of select cognitive domains with rosiglitazone implicates dorsal hippocampus circuitry sensitive to PPARγ agonism in an Alzheimer's mouse model.
    Brain and behavior, 2021, Volume: 11, Issue:2

    Topics: Aged; Alzheimer Disease; Animals; Cognition; Diabetes Mellitus, Type 2; Disease Models, Animal; Hippocampus; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; PPAR gamma; Proteomics; Rosiglitazone

2021
Combination therapy with semaglutide and rosiglitazone as a synergistic treatment for diabetic retinopathy in rodent animals.
    Life sciences, 2021, Mar-15, Volume: 269

    Topics: Animals; Antioxidants; Cell Line; Cell Survival; Diabetic Retinopathy; Disease Models, Animal; Drug Therapy, Combination; Ependymoglial Cells; Glial Fibrillary Acidic Protein; Glucagon-Like Peptides; Humans; Inflammation; Male; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; TOR Serine-Threonine Kinases

2021
PPARγ activation suppresses the expression of MMP9 by downregulating NF-κB post intracerebral hemorrhage.
    Neuroscience letters, 2021, 05-01, Volume: 752

    Topics: Anilides; Animals; Cell Line; Cerebral Hemorrhage; Disease Models, Animal; Down-Regulation; Humans; Male; Matrix Metalloproteinase 9; Mice; NF-kappa B; Phenylenediamines; PPAR gamma; Rats; Rosiglitazone

2021
ESE3/EHF, a promising target of rosiglitazone, suppresses pancreatic cancer stemness by downregulating CXCR4.
    Gut, 2022, Volume: 71, Issue:2

    Topics: Animals; Cohort Studies; Disease Models, Animal; Humans; Hypoglycemic Agents; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Pancreatic Neoplasms; Pancreatic Stellate Cells; Receptors, CXCR4; Rosiglitazone; Transcription Factors

2022
The Crucial Role of PPARγ-Egr-1-Pro-Inflammatory Mediators Axis in IgG Immune Complex-Induced Acute Lung Injury.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Cytokines; Disease Models, Animal; Early Growth Response Protein 1; Gene Expression Regulation; HEK293 Cells; Humans; Immunoglobulin G; Inflammation Mediators; Lung; Macrophages; Male; Mice; Mice, Inbred C57BL; PPAR gamma; RAW 264.7 Cells; Rosiglitazone; Signal Transduction

2021
Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging C57BL/6 mice and in vitro studies.
    Scientific reports, 2021, 05-14, Volume: 11, Issue:1

    Topics: Adipogenesis; Aging; Animals; Bone Diseases, Metabolic; Cell Differentiation; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Fatty Acids, Omega-3; Female; Humans; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Primary Cell Culture; RAW 264.7 Cells; Rosiglitazone

2021
Rosiglitazone ameliorated airway inflammation induced by cigarette smoke via inhibiting the M1 macrophage polarization by activating PPARγ and RXRα.
    International immunopharmacology, 2021, Volume: 97

    Topics: Animals; Cigarette Smoking; Disease Models, Animal; Humans; Lung; Macrophage Activation; Macrophages, Alveolar; Male; Nicotiana; Pneumonia; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Rats; Rosiglitazone; Smoke

2021
Preventive effect of rosiglitazone on liver injury in a mouse model of decompression sickness.
    Diving and hyperbaric medicine, 2017, Volume: 47, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Decompression Sickness; Disease Models, Animal; E-Selectin; Erythrocyte Count; Hypoglycemic Agents; L-Lactate Dehydrogenase; Leukocyte Count; Liver; Male; Mice; Mice, Inbred ICR; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Platelet Count; Random Allocation; Rosiglitazone; Thiazolidinediones

2017
Insulin Resistance Disrupts the Interaction Between AKT and the NMDA Receptor and the Inactivation of the CaMKIV/CREB Pathway in Minimal Hepatic Encephalopathy.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, 10-01, Volume: 159, Issue:2

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hepatic Encephalopathy; Hippocampus; Hypoglycemic Agents; Insulin Resistance; Maze Learning; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Receptors, N-Methyl-D-Aspartate; Rosiglitazone; Thiazolidinediones

2017
Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in
    Diabetes, 2017, Volume: 66, Issue:8

    Topics: Animals; Biomarkers; Blood Glucose; Cell Dedifferentiation; Diabetes Mellitus, Type 2; Disease Models, Animal; Eating; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Mice; Phlorhizin; Rosiglitazone; Thiazolidinediones

2017
FAM3A mediates PPARγ's protection in liver ischemia-reperfusion injury by activating Akt survival pathway and repressing inflammation and oxidative stress.
    Oncotarget, 2017, Jul-25, Volume: 8, Issue:30

    Topics: Animals; Apoptosis; Cell Survival; Cytokines; Disease Models, Animal; Disease Progression; Gene Expression; Hepatocytes; Liver Diseases; Liver Function Tests; Male; Mice; Mice, Knockout; Oxidative Stress; PPAR gamma; Protein Transport; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Rosiglitazone; Signal Transduction; Thiazolidinediones

2017
Rosiglitazone Improves Insulin Resistance Mediated by 10,12 Conjugated Linoleic Acid in a Male Mouse Model of Metabolic Syndrome.
    Endocrinology, 2017, 09-01, Volume: 158, Issue:9

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Body Weight; Disease Models, Animal; Glucose; Insulin Resistance; Linoleic Acids, Conjugated; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Receptors, LDL; Rosiglitazone; Thiazolidinediones

2017
Metformin HCl has curative effect on rebuilding of ventricular diastolic functions in high-fat-diet fed rats.
    Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:3(Suppl.)

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Liver; Male; Metformin; Myocardium; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Rosiglitazone; Ventricular Dysfunction, Left; Ventricular Function, Left

2017
Progressive Renal Disease Established by Renin-Coding Adeno-Associated Virus-Driven Hypertension in Diverse Diabetic Models.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:2

    Topics: Animals; Antihypertensive Agents; Creatinine; Dependovirus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Female; Genetic Vectors; Hypertension; Hypoglycemic Agents; Janus Kinases; Lac Operon; Lisinopril; Male; Mice; Nephrectomy; Nitric Oxide Synthase Type III; Renin; Rosiglitazone; Serum Albumin; Severity of Illness Index; Signal Transduction; STAT Transcription Factors

2018
Rosiglitazone Infusion Therapy Following Minimally Invasive Surgery for Intracranial Hemorrhage Evacuation Decreased Perihematomal Glutamate Content and Blood-Brain Barrier Permeability in Rabbits.
    World neurosurgery, 2018, Volume: 111

    Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Disease Models, Animal; Glutamic Acid; Hypoglycemic Agents; Intracranial Hemorrhages; Male; Minimally Invasive Surgical Procedures; PPAR gamma; Rabbits; Random Allocation; Rosiglitazone; Thiazolidinediones

2018
Insulin degrading enzyme contributes to the pathology in a mixed model of Type 2 diabetes and Alzheimer's disease: possible mechanisms of IDE in T2D and AD.
    Bioscience reports, 2018, 02-28, Volume: 38, Issue:1

    Topics: Alzheimer Disease; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Amyloid beta-Peptides; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Gene Expression Regulation; Glucose Tolerance Test; Humans; Insulin; Insulysin; Learning; Mice; Mice, Transgenic; PPAR gamma; Ribonucleotides; Rosiglitazone; Streptozocin; Thiazolidinediones

2018
Evaluation of Uracil, Sodium Ascorbate, and Rosiglitazone as Promoters of Urinary Bladder Transitional Cell Carcinomas in Male Sprague-Dawley Rats.
    Toxicologic pathology, 2018, Volume: 46, Issue:2

    Topics: Animals; Ascorbic Acid; Carcinogens; Carcinoma, Transitional Cell; Disease Models, Animal; Male; Rats; Rats, Sprague-Dawley; Rosiglitazone; Uracil; Urinary Bladder; Urinary Bladder Neoplasms

2018
PPAR-gamma activation is associated with reduced liver ischemia-reperfusion injury and altered tissue-resident macrophages polarization in a mouse model.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Alanine Transaminase; Anilides; Animals; Apoptosis; Aspartate Aminotransferases; Cell Polarity; Cytokines; Disease Models, Animal; Kupffer Cells; Lectins, C-Type; Liver; Male; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred C57BL; Necrosis; Nitric Oxide; PPAR gamma; Receptors, Cell Surface; Reperfusion Injury; Rosiglitazone; Thiazolidinediones

2018
The antidepressant effects of rosiglitazone on rats with depression induced by neuropathic pain.
    Life sciences, 2018, Jun-15, Volume: 203

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Hindlimb Suspension; Hypoglycemic Agents; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Rosiglitazone; Stress, Psychological; Thiazolidinediones

2018
Peroxisome proliferator-activated receptor gamma activation promotes intestinal barrier function by improving mucus and tight junctions in a mouse colitis model.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2018, Volume: 50, Issue:11

    Topics: Animals; Caco-2 Cells; Colitis; Dextran Sulfate; Disease Models, Animal; HT29 Cells; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mucin-2; Mucus; Myosin-Light-Chain Kinase; Permeability; Phosphorylation; PPAR gamma; Rosiglitazone; Signal Transduction; Tight Junctions

2018
Joint contracture is reduced by intra-articular implantation of rosiglitazone-loaded hydrogels in a rabbit model of arthrofibrosis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2018, Volume: 36, Issue:11

    Topics: Animals; Cells, Cultured; Contracture; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fibroblasts; Fibrosis; Humans; Hypoglycemic Agents; Polyesters; Polyethylene Glycols; Rabbits; Rosiglitazone; Tissue Scaffolds

2018
PPARγ agonist rosiglitazone alters the temporal and spatial distribution of inflammation during abdominal aortic aneurysm formation.
    Molecular medicine reports, 2018, Volume: 18, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Disease Models, Animal; Inflammation; Male; Mice; Mice, Knockout; Models, Biological; PPAR gamma; Rosiglitazone; Th2 Cells; Thiazolidinediones; Vasodilator Agents

2018
[Protective effects of rosiglitazone on hepatic ischemia reperfusion injury in rats].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Jul-28, Volume: 43, Issue:7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Disease Models, Animal; Glutathione Peroxidase; L-Lactate Dehydrogenase; Ligation; Liver; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones

2018
Inhibiting role of rosiglitazone in the regulation of inflammatory response and protective effects for severe acute pancreatitis in mice.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:1

    Topics: Animals; Ceruletide; Disease Models, Animal; Early Growth Response Protein 1; Female; Inflammation; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred ICR; Pancreatitis; Protective Agents; RNA, Messenger; Rosiglitazone; Severity of Illness Index; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein

2019
The potential role of HO-1 in regulating the MLK3-MKK7-JNK3 module scaffolded by JIP1 during cerebral ischemia/reperfusion in rats.
    Behavioural brain research, 2019, 02-01, Volume: 359

    Topics: Adaptor Proteins, Signal Transducing; Animals; Brain Ischemia; CA1 Region, Hippocampal; Cell Death; Disease Models, Animal; Down-Regulation; Heme Oxygenase (Decyclizing); Male; MAP Kinase Kinase Kinases; Maze Learning; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase Kinase Kinase 11; Mitogen-Activated Protein Kinases; Neurons; Neuroprotection; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins c-jun; Rats, Sprague-Dawley; Reperfusion Injury; Rosiglitazone

2019
Prenatal treatment with rosiglitazone attenuates vascular remodeling and pulmonary monocyte influx in experimental congenital diaphragmatic hernia.
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Animals; Chemokine CCL2; Disease Models, Animal; Female; Gene Expression; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Macrophages; Monocytes; Phenyl Ethers; Pregnancy; Prenatal Care; Rats; RNA, Messenger; Rosiglitazone; Vascular Remodeling

2018
Peroxisome Proliferator-Activated Receptor γ Agonist Rosiglitazone Protects Blood-Brain Barrier Integrity Following Diffuse Axonal Injury by Decreasing the Levels of Inflammatory Mediators Through a Caveolin-1-Dependent Pathway.
    Inflammation, 2019, Volume: 42, Issue:3

    Topics: Animals; Blood-Brain Barrier; Caveolin 1; Cells, Cultured; Diffuse Axonal Injury; Disease Models, Animal; Endothelial Cells; Glucose; Humans; Inflammation Mediators; PPAR gamma; Rats; Rosiglitazone; Tight Junction Proteins

2019
Comparison of efficacy of SHENQI compound and rosiglitazone in the treatment of diabetic vasculopathy analyzing multi-factor mediated disease-causing modules.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Animals; Aorta, Abdominal; Cardiovascular Agents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression; Humans; Hypoglycemic Agents; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phytotherapy; Rosiglitazone; Signal Transduction

2018
Peroxisome Proliferator Activated Receptor gamma (PPARγ) Agonist Rosiglitazone Ameliorate Airway Inflammation by Inhibiting Toll-Like Receptor 2 (TLR2)/Nod-Like Receptor with Pyrin Domain Containing 3 (NLRP3) Inflammatory Corpuscle Activation in Asthmatic
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Dec-13, Volume: 24

    Topics: Animals; Asthma; CARD Signaling Adaptor Proteins; Disease Models, Animal; Female; Inflammation; Mice; Mice, Inbred C57BL; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones; Toll-Like Receptor 2

2018
Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats.
    Transplant immunology, 2019, Volume: 54

    Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Graft Rejection; Humans; Kidney; Kidney Transplantation; Macrophages; Male; PPAR gamma; Rats; Rats, Inbred Lew; Rosiglitazone; Signal Transduction; Transforming Growth Factor beta

2019
Beneficial effects of rosiglitazone, a peroxisome proliferator-activated receptor-γ agonist, in a mouse allergic asthma model is not associated with the recruitment or generation of Foxp3-expressing CD4
    European journal of pharmacology, 2019, Apr-05, Volume: 848

    Topics: Animals; Asthma; CD4 Lymphocyte Count; Disease Models, Animal; Forkhead Transcription Factors; Gene Expression; Hypersensitivity; Mice; Mice, Inbred BALB C; Ovalbumin; PPAR gamma; Rosiglitazone; T-Lymphocytes, Regulatory; Treatment Outcome

2019
Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis.
    Redox biology, 2019, Volume: 22

    Topics: Adipose Tissue; Animals; Biomarkers; Blood Glucose; Body Weight; Diet, High-Fat; Disease Models, Animal; Glucose Intolerance; Hepatocytes; Lipid Metabolism; Male; Mice; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Obesity; Oleic Acids; Protective Agents; Rosiglitazone; Triglycerides

2019
PPARγ activation serves as therapeutic strategy against bladder cancer via inhibiting PI3K-Akt signaling pathway.
    BMC cancer, 2019, Mar-07, Volume: 19, Issue:1

    Topics: Animals; Apoptosis; Biomarkers; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Gene Expression Profiling; Humans; Immunohistochemistry; Male; Mice; Models, Biological; Phosphatidylinositol 3-Kinases; PPAR gamma; Prognosis; Proto-Oncogene Proteins c-akt; Rosiglitazone; Signal Transduction; Transcriptome; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2019
Rosiglitazone promotes ENaC-mediated alveolar fluid clearance in acute lung injury through the PPARγ/SGK1 signaling pathway.
    Cellular & molecular biology letters, 2019, Volume: 24

    Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Epithelial Sodium Channels; Inflammation Mediators; Lipopolysaccharides; Lung; Male; Mice, Inbred C57BL; Phosphorylation; PPAR gamma; Protein Serine-Threonine Kinases; Rosiglitazone; Signal Transduction

2019
Rosiglitazone Treatment Prevents Postoperative Fibrosis in a Rabbit Model of Glaucoma Filtration Surgery.
    Investigative ophthalmology & visual science, 2019, 06-03, Volume: 60, Issue:7

    Topics: Actins; Animals; Autophagy; Blotting, Western; Conjunctiva; Connective Tissue Growth Factor; Disease Models, Animal; Fibroblasts; Fibrosis; Glaucoma; Hypoglycemic Agents; Intraocular Pressure; Male; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Polymerase Chain Reaction; Postoperative Complications; Rabbits; Real-Time Polymerase Chain Reaction; Rosiglitazone; Tenon Capsule; Trabeculectomy; Transforming Growth Factor beta1

2019
Peroxisome Proliferator-Activated Receptor-gamma agonists exhibit anti-inflammatory and antiviral effects in an EcoHIV mouse model.
    Scientific reports, 2019, 07-01, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Brain; Cells, Cultured; Disease Models, Animal; HIV Core Protein p24; HIV Infections; HIV-1; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Neuroglia; Nitric Oxide Synthase Type II; Oxidative Stress; Pioglitazone; PPAR gamma; Rosiglitazone; Tumor Necrosis Factor-alpha

2019
Effects of rosiglitazone/PHBV drug delivery system on postoperative fibrosis in rabbit glaucoma filtration surgery model.
    Drug delivery, 2019, Volume: 26, Issue:1

    Topics: Animals; Cicatrix; Conjunctiva; Cornea; Disease Models, Animal; Drug Delivery Systems; Fibrosis; Filtering Surgery; Glaucoma; Intraocular Pressure; Polyesters; Rabbits; Rosiglitazone; Wound Healing

2019
Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease--a historical prospective.
    Lipids in health and disease, 2013, Mar-25, Volume: 12

    Topics: Animals; Bezafibrate; Disease Models, Animal; Fatty Liver; Fructose; Gene Expression; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Non-alcoholic Fatty Liver Disease; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones

2013
Rosiglitazone treatment of type 2 diabetic db/db mice attenuates urinary albumin and angiotensin converting enzyme 2 excretion.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: ADAM Proteins; ADAM17 Protein; Albuminuria; Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Glucose Tolerance Test; Glycosuria; Hyperglycemia; Hypoglycemic Agents; Kidney Diseases; Male; Membrane Proteins; Mice; Peptidyl-Dipeptidase A; Rosiglitazone; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-3; Triglycerides

2013
Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuates inflammatory pain through the induction of heme oxygenase-1 in macrophages.
    Pain, 2013, Volume: 154, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Clodronic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Gene Expression Regulation; Heme Oxygenase-1; Hyperalgesia; Inflammation; Lectins, C-Type; Macrophages, Peritoneal; Male; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Pain; Pain Measurement; Pain Threshold; Receptors, Cell Surface; Rosiglitazone; Thiazolidinediones; Time Factors

2013
High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling.
    Diabetes, 2013, Volume: 62, Issue:11

    Topics: Aging; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fibroblast Growth Factors; Glucose; Islets of Langerhans; Klotho Proteins; Male; Membrane Proteins; Mice; Phosphorylation; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones

2013
[Effects of curcumin on expression of PI3K and p-pI3K in hippocampus of AD mice].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:9

    Topics: Alzheimer Disease; Animals; Curcumin; Disease Models, Animal; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Rosiglitazone; Thiazolidinediones

2013
Rosiglitazone and imidapril alone or in combination alleviate muscle and adipose depletion in a murine cancer cachexia model.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:1

    Topics: Adipose Tissue; Animals; Biomarkers; Body Weight; Cachexia; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Gene Expression Regulation; Imidazolidines; Inflammation Mediators; Insulin; Male; Mice; Muscle Proteins; Muscles; Muscular Atrophy; Neoplasms; Organ Size; Rosiglitazone; SKP Cullin F-Box Protein Ligases; Thiazolidinediones; Tripartite Motif Proteins; Tumor Burden; Ubiquitin-Protein Ligases

2014
Rosiglitazone attenuates casein-induced hepatic endoplasmic reticulum stress in Sprague-Dawley rats: a novel model of endoplasmic reticulum stress.
    Endocrine journal, 2013, Volume: 60, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Body Weight; Caseins; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Endoplasmic Reticulum Stress; Inflammation; Liver; Male; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones

2013
Effects of rosiglitazone on the growth and lymphangiogenesis of human gastric cancer transplanted in nude mice.
    Oncology reports, 2013, Volume: 30, Issue:6

    Topics: Animals; Cell Proliferation; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Lymphangiogenesis; Lymphatic Metastasis; Mice; Mice, Nude; RNA, Messenger; Rosiglitazone; Stomach Neoplasms; Thiazolidinediones; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor Receptor-3

2013
Increased susceptibility of db/db mice to rosiglitazone-induced plasma volume expansion: role of dysregulation of renal water transporters.
    American journal of physiology. Renal physiology, 2013, Nov-15, Volume: 305, Issue:10

    Topics: Animals; Aquaporin 2; Aquaporin 3; Biological Transport; Blood Glucose; Body Water; Diabetes Mellitus; Disease Models, Animal; Diuresis; Humans; Hypoglycemic Agents; Kidney; Male; Mice; Natriuresis; Osmolar Concentration; Plasma Volume; PPAR gamma; Rosiglitazone; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Solute Carrier Family 12, Member 1; Thiazolidinediones; Triglycerides; Water-Electrolyte Balance; Water-Electrolyte Imbalance; Weight Gain

2013
Antidiabetic-drug combination treatment for glucose intolerance in adult female rats treated acutely with olanzapine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Jan-03, Volume: 48

    Topics: Animals; Benzodiazepines; Disease Models, Animal; Drug Therapy, Combination; Fasting; Female; Glucose Intolerance; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; Insulin; Metformin; Olanzapine; Rats; Rats, Sprague-Dawley; Rosiglitazone; Selective Serotonin Reuptake Inhibitors; Thiazolidinediones; Time Factors

2014
Regulation of cigarette smoke-induced toll-like receptor 4 expression by peroxisome proliferator-activated receptor-gamma agonists in bronchial epithelial cells.
    Respirology (Carlton, Vic.), 2013, Volume: 18 Suppl 3

    Topics: Animals; Benzhydryl Compounds; Bronchi; Cell Survival; Cells, Cultured; Disease Models, Animal; Down-Regulation; Epithelial Cells; Epoxy Compounds; In Vitro Techniques; Interleukin-8; Leukotriene B4; Male; NF-kappa B; Pneumonia; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Smoking; Thiazolidinediones; Toll-Like Receptor 4; Up-Regulation

2013
Rosiglitazone induces cardiotoxicity by accelerated apoptosis.
    Cardiovascular toxicology, 2014, Volume: 14, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cell Differentiation; Cell Line; Cell Survival; Diabetes Mellitus; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Heart Diseases; Heme Oxygenase (Decyclizing); Hypoglycemic Agents; Male; Mice; Myocytes, Cardiac; NADPH Oxidases; NF-E2-Related Factor 2; Nitric Oxide Synthase; Oxidative Phosphorylation; Oxidative Stress; Protein Kinase C-delta; Rats; Rosiglitazone; Signal Transduction; Superoxides; Thiazolidinediones; Time Factors

2014
Assessment of pharmacokinetic interaction of spirulina with glitazone in a type 2 diabetes rat model.
    Journal of medicinal food, 2013, Volume: 16, Issue:12

    Topics: Animals; Dexamethasone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Hypoglycemic Agents; Insulin Resistance; Male; Pioglitazone; Rats; Rats, Wistar; Rosiglitazone; Spirulina; Thiazolidinediones

2013
APOE*3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome.
    Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Apolipoprotein E3; Atorvastatin; Cholesterol Ester Transfer Proteins; Disease Models, Animal; Fenofibrate; Glucagon-Like Peptide 1; Heptanoic Acids; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Liraglutide; Male; Metabolic Syndrome; Mice, Transgenic; Niacin; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Rosiglitazone; Thiazolidinediones

2014
Activation of PPAR-γ ameliorates pulmonary arterial hypertension via inducing heme oxygenase-1 and p21(WAF1): an in vivo study in rats.
    Life sciences, 2014, Mar-07, Volume: 98, Issue:1

    Topics: Animals; Blotting, Western; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Gene Expression Regulation; Heme Oxygenase-1; Hypertension, Pulmonary; Hypoglycemic Agents; Immunoblotting; Male; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones

2014
Rosiglitazone and fenofibrate exacerbate liver steatosis in a mouse model of obesity and hyperlipidemia. A transcriptomic and metabolomic study.
    Journal of proteome research, 2014, Mar-07, Volume: 13, Issue:3

    Topics: Animals; Disease Models, Animal; Fatty Liver; Fenofibrate; Gene Expression Profiling; Gene Expression Regulation; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Metabolome; Mice; Mice, Transgenic; Obesity; Peroxisome Proliferator-Activated Receptors; Protein Interaction Mapping; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcriptome

2014
Rosiglitazone dampens pulmonary inflammation in a porcine model of acute lung injury.
    Inflammation, 2014, Volume: 37, Issue:4

    Topics: Acute Lung Injury; Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Bronchoscopy; Catheterization; Disease Models, Animal; Endotoxins; Hemodynamics; Hypoglycemic Agents; Inflammation; Infusions, Intravenous; Lipopolysaccharides; Lung; Peroxidase; Pulmonary Alveoli; Rosiglitazone; Swine; Thiazolidinediones

2014
Insulin sensitization by a novel partial peroxisome proliferator-activated receptor γ agonist with protein tyrosine phosphatase 1B inhibitory activity in experimental osteoporotic rats.
    Journal of pharmacological sciences, 2014, Volume: 124, Issue:2

    Topics: Adipocytes; Animals; Bone Density; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Isoquinolines; Osteoblasts; Osteoporosis, Postmenopausal; Ovariectomy; Oxazoles; PPAR gamma; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Rats, Inbred F344; Receptor, Insulin; Risk; Rosiglitazone; Thiazolidinediones; Triglycerides

2014
Rosiglitazone synergizes the neuroprotective effects of valproic acid against quinolinic acid-induced neurotoxicity in rats: targeting PPARγ and HDAC pathways.
    Neurotoxicity research, 2014, Volume: 26, Issue:2

    Topics: Animals; Body Weight; Brain; Disease Models, Animal; Drug Synergism; Histone Deacetylase Inhibitors; Histone Deacetylases; Huntington Disease; Male; Maze Learning; Motor Activity; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes; PPAR gamma; Quinolinic Acid; Rats, Wistar; Rosiglitazone; Signal Transduction; Thiazolidinediones; Valproic Acid

2014
PPARγ agonists improve survival and neurocognitive outcomes in experimental cerebral malaria and induce neuroprotective pathways in human malaria.
    PLoS pathogens, 2014, Volume: 10, Issue:3

    Topics: Animals; Antimalarials; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Malaria, Cerebral; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; PPAR gamma; Randomized Controlled Trials as Topic; Real-Time Polymerase Chain Reaction; Ribonuclease, Pancreatic; Rosiglitazone; Thiazolidinediones

2014
Exendin-4 shows no effects on the prostatic index in high-fat-diet-fed rat with benign prostatic hyperplasia by improving insulin resistance.
    Andrologia, 2015, Volume: 47, Issue:2

    Topics: Animals; Body Weight; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Exenatide; Glucagon-Like Peptide-1 Receptor; Insulin Resistance; Male; Peptides; Prostate; Prostatic Hyperplasia; Rats; Rats, Wistar; Receptors, Glucagon; Rosiglitazone; Severity of Illness Index; Thiazolidinediones; Venoms

2015
Rosiglitazone modulates pigeon atherosclerotic lipid accumulation and gene expression in vitro.
    Poultry science, 2014, Volume: 93, Issue:6

    Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; Bird Diseases; Cardiotonic Agents; Columbidae; Disease Models, Animal; Gene Expression Regulation; Humans; Lipid Metabolism; Myocytes, Smooth Muscle; PPAR gamma; Proto-Oncogene Proteins c-myc; Rosiglitazone; Thiazolidinediones

2014
Effects of analog P165 of amyloid precursor protein 5-mer peptide on learning, memory and brain insulin receptors in the rat model of cognitive decline.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35, Issue:11

    Topics: Amyloid beta-Protein Precursor; Animals; Brain; Cognition Disorders; Disease Models, Animal; Hypoglycemic Agents; Insulin; Male; Maze Learning; Memory; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Rosiglitazone; Signal Transduction; Streptozocin; Thiazolidinediones

2014
Rosiglitazone reduces body wasting and improves survival in a rat model of cancer cachexia.
    Nutrition (Burbank, Los Angeles County, Calif.), 2014, Volume: 30, Issue:9

    Topics: Adipose Tissue; Animals; Body Composition; Body Fluid Compartments; Cachexia; Cardiac Output; Disease Models, Animal; Heart; Hypoglycemic Agents; Male; Muscle, Skeletal; Neoplasms; Random Allocation; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Ventricular Function, Left; Weight Loss

2014
Rosiglitazone attenuates cerebral vasospasm and provides neuroprotection in an experimental rat model of subarachnoid hemorrhage.
    Neurocritical care, 2014, Volume: 21, Issue:2

    Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Neuroprotective Agents; Random Allocation; Rats; Rosiglitazone; Subarachnoid Hemorrhage; Thiazolidinediones; Vasospasm, Intracranial

2014
Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:4

    Topics: Alzheimer Disease; Animals; Body Weight; Brain; Disease Models, Animal; Exploratory Behavior; Female; Hypoglycemic Agents; Learning Disabilities; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neuroimmunomodulation; Neuroprotective Agents; Nootropic Agents; Phosphorylation; Pioglitazone; Proto-Oncogene Proteins c-akt; Rosiglitazone; Spatial Learning; tau Proteins; Thiazolidinediones

2015
Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease.
    Neurobiology of disease, 2014, Volume: 71

    Topics: Animals; Cell Count; Cell Polarity; Cytokines; Disease Models, Animal; Gene Expression Regulation; Mice; Microglia; MPTP Poisoning; Nerve Degeneration; Neuroprotective Agents; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Tyrosine 3-Monooxygenase

2014
The role of rosiglitazone in the proliferation of vascular smooth muscle cells after experimental subarachnoid hemorrhage.
    Acta neurochirurgica, 2014, Volume: 156, Issue:11

    Topics: Animals; Basilar Artery; Caveolin 1; Cell Proliferation; Disease Models, Animal; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Rosiglitazone; Subarachnoid Hemorrhage; Thiazolidinediones; Up-Regulation; Vasoconstriction; Vasodilator Agents; Vasospasm, Intracranial

2014
Anti-inflammatory effect of peroxisome proliferator-activated receptor-γ (PPAR-γ) on non-obese diabetic mice with Sjogren's syndrome.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Hypoglycemic Agents; Immunohistochemistry; Mice; Mice, Inbred NOD; PPAR gamma; Real-Time Polymerase Chain Reaction; Rosiglitazone; Sjogren's Syndrome; Thiazolidinediones

2014
[Rosiglitazone improves learning and memory impairment of 3 x Tg mice].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Glycosylation; Learning; Memory; Memory Disorders; Mice; Mice, Transgenic; Neurofilament Proteins; Phosphorylation; Rosiglitazone; tau Proteins; Thiazolidinediones

2014
Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone.
    Molecular psychiatry, 2015, Volume: 20, Issue:6

    Topics: Animals; Carboxypeptidase H; Cells, Cultured; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Food Preferences; Hippocampus; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neurogenesis; Neuropeptides; Rosiglitazone; Stress, Psychological; Sucrose; Sweetening Agents; Swimming; Thiazolidinediones; Up-Regulation

2015
Central activation of PPAR-gamma ameliorates diabetes induced cognitive dysfunction and improves BDNF expression.
    Neurobiology of aging, 2015, Volume: 36, Issue:3

    Topics: Administration, Oral; Animals; Brain-Derived Neurotrophic Factor; Cognition Disorders; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression; Hippocampus; Hypoglycemic Agents; Injections, Intraventricular; Insulin Resistance; Male; Memory; Mice, Inbred C57BL; Molecular Targeted Therapy; Neuronal Plasticity; PPAR gamma; Rosiglitazone; Thiazolidinediones

2015
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:6

    Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Kidney; Kidney Diseases; Male; NAD; NADP; PPAR gamma; Prostaglandin D2; Protective Agents; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Urea; Uric Acid

2014
Protective effects of Sparstolonin B, a selective TLR2 and TLR4 antagonist, on mouse endotoxin shock.
    Cytokine, 2015, Volume: 75, Issue:2

    Topics: Animals; Body Temperature; Cell Line; Chemokine CCL2; Disease Models, Animal; Drugs, Chinese Herbal; Female; Heterocyclic Compounds, 4 or More Rings; Inflammation; Interleukin-1beta; Interleukin-6; Lipopeptides; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; PPAR gamma; Rosiglitazone; Sepsis; Shock, Septic; Thiazolidinediones; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2015
Rosiglitazone attenuates atherosclerosis and increases high-density lipoprotein function in atherosclerotic rabbits.
    International journal of molecular medicine, 2015, Volume: 35, Issue:3

    Topics: Animals; Aryldialkylphosphatase; Atherosclerosis; ATP Binding Cassette Transporter 1; Cholesterol; Disease Models, Animal; Enzyme Activation; Gene Expression; Hepatocytes; Hypoglycemic Agents; Lipids; Lipoproteins, HDL; Macrophages, Peritoneal; Male; Peroxidase; Rabbits; Rosiglitazone; Scavenger Receptors, Class B; Thiazolidinediones

2015
The PPARγ agonist, rosiglitazone, attenuates airway inflammation and remodeling via heme oxygenase-1 in murine model of asthma.
    Acta pharmacologica Sinica, 2015, Volume: 36, Issue:2

    Topics: Animals; Asthma; Disease Models, Animal; Female; Heme Oxygenase-1; Inflammation; Lung; Membrane Proteins; Mice; Mice, Inbred BALB C; PPAR gamma; Rosiglitazone; Thiazolidinediones

2015
Neuroinflammation and neuronal autophagic death were suppressed via Rosiglitazone treatment: New evidence on neuroprotection in a rat model of global cerebral ischemia.
    Journal of the neurological sciences, 2015, Feb-15, Volume: 349, Issue:1-2

    Topics: Animals; Autophagy; Brain Edema; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Female; Inflammation; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Rosiglitazone; Thiazolidinediones

2015
Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis.
    Scientific reports, 2015, Apr-01, Volume: 5

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Benzamides; Cell Differentiation; Cyclin-Dependent Kinase 5; Diabetes Mellitus, Experimental; Disease Models, Animal; Hyperglycemia; Indoles; Mice; Osteoblasts; Osteogenesis; Phosphorylation; PPAR gamma; Protein Binding; Rosiglitazone; Thiazolidinediones

2015
Macrophage PPARγ and impaired wound healing in type 2 diabetes.
    The Journal of pathology, 2015, Volume: 236, Issue:4

    Topics: Administration, Cutaneous; Animals; Cells, Cultured; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Humans; Interleukin-1beta; Leg Ulcer; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Phenotype; PPAR gamma; Prostaglandin D2; Receptors, Interleukin-1 Type I; Rosiglitazone; Skin; Thiazolidinediones; Time Factors; Wound Healing

2015
Rosiglitazone attenuates the metalloprotease/anti-metalloprotease imbalance in emphysema induced by cigarette smoke: involvement of extracellular signal-regulated kinase and NFκB signaling.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Administration, Oral; Animals; Apoptosis; Cytoprotection; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; I-kappa B Proteins; Inhalation Exposure; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; PPAR gamma; Pulmonary Emphysema; Rats, Wistar; Rosiglitazone; Signal Transduction; Smoke; Thiazolidinediones; Tobacco Smoke Pollution

2015
Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice.
    Neuroscience, 2015, 08-27, Volume: 302

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Encephalitis; Humans; Hydrogen Peroxide; Hypoglycemic Agents; Lipopolysaccharides; Male; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Neurotoxins; NF-kappa B; Parkinsonian Disorders; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Thiobarbiturates; Tyrosine 3-Monooxygenase

2015
Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood-brain barrier disruption in rabbits.
    BMC neurology, 2015, Mar-17, Volume: 15

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Injuries; Cerebral Hemorrhage; Disease Models, Animal; Hematoma; Hypoglycemic Agents; Infusions, Intraventricular; Male; Matrix Metalloproteinase 9; Minimally Invasive Surgical Procedures; Permeability; PPAR gamma; Rabbits; Random Allocation; Rosiglitazone; Thiazolidinediones

2015
Rosiglitazone, a Peroxisome Proliferator-Activated Receptor (PPAR)-γ Agonist, Attenuates Inflammation Via NF-κB Inhibition in Lipopolysaccharide-Induced Peritonitis.
    Inflammation, 2015, Volume: 38, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; CD40 Antigens; Disease Models, Animal; Gene Expression Regulation; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Interleukin-6; Lipopolysaccharides; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Peritoneum; Peritonitis; Phosphorylation; PPAR gamma; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazolidinediones; Time Factors; Transcription Factor RelA

2015
In-vivo antioxidant and anti-inflammatory activity of rosiglitazone, a peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonists in animal model of bronchial asthma.
    The Journal of pharmacy and pharmacology, 2015, Volume: 67, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Catalase; Disease Models, Animal; Glutathione; Guinea Pigs; Immunoglobulin E; Interleukin-5; Male; Ovalbumin; PPAR gamma; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones

2015
[Effects of rosiglitazone on levels of TNFα in septic rats with acute kidney injury].
    Zhonghua yi xue za zhi, 2015, May-19, Volume: 95, Issue:19

    Topics: Acute Kidney Injury; Animals; Cecum; Disease Models, Animal; Inflammation; Kidney; Ligation; Male; Punctures; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sepsis; Thiazolidinediones; Tumor Necrosis Factor-alpha

2015
Rosiglitazone attenuates renal injury caused by hyperlipidemic pancreatitis.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:5

    Topics: Acute Kidney Injury; Animals; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hyperlipidemias; Hypoglycemic Agents; Immunohistochemistry; In Situ Nick-End Labeling; Male; Pancreatitis; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones

2015
Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes.
    Molecular endocrinology (Baltimore, Md.), 2015, Volume: 29, Issue:9

    Topics: Adipocytes, White; Adipose Tissue, Brown; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Metabolism; High-Throughput Screening Assays; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; PPAR gamma; RNA Interference; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; Ubiquitin-Conjugating Enzymes

2015
PPARα/γ agonists and antagonists differently affect hepatic lipid metabolism, oxidative stress and inflammatory cytokine production in steatohepatitic rats.
    Cytokine, 2015, Volume: 75, Issue:1

    Topics: Anilides; Animals; Chemokine CCL2; Cytokines; Disease Models, Animal; Fatty Acids, Nonesterified; Fenofibrate; Gene Expression Regulation; Glutathione; Indoles; Inflammation; Interleukin-6; Interleukin-8; Lipid Metabolism; Liver; Male; Malondialdehyde; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones; Tumor Necrosis Factor-alpha

2015
Rosiglitazone attenuates early brain injury after experimental subarachnoid hemorrhage in rats.
    Brain research, 2015, Oct-22, Volume: 1624

    Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Caspase 3; Cyclin D1; Disease Models, Animal; In Situ Nick-End Labeling; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Rosiglitazone; Subarachnoid Hemorrhage; Thiazolidinediones

2015
Rosiglitazone Promotes White Matter Integrity and Long-Term Functional Recovery After Focal Cerebral Ischemia.
    Stroke, 2015, Volume: 46, Issue:9

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Microglia; Oligodendroglia; PPAR gamma; Recovery of Function; Reperfusion; Rosiglitazone; Thiazolidinediones; White Matter

2015
Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain; Brain Injuries; Caspase 3; Disease Models, Animal; Female; Interleukin-6; Neuroprotective Agents; PPAR gamma; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2015
Padina arborescens Ameliorates Hyperglycemia and Dyslipidemia in C57BL/KsJ-db/db Mice, a Model of Type 2 Diabetes Mellitus.
    Journal of medicinal food, 2015, Volume: 18, Issue:10

    Topics: Adiponectin; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Dyslipidemias; Fasting; Glucose Tolerance Test; Glycated Hemoglobin; Glycogen; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Mice; Mice, Inbred C57BL; Phaeophyceae; Rosiglitazone; Thiazolidinediones

2015
Rosiglitazone activation of PPARγ-dependent signaling is neuroprotective in mutant huntingtin expressing cells.
    Experimental cell research, 2015, Nov-01, Volume: 338, Issue:2

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; DNA-Binding Proteins; Endoplasmic Reticulum Stress; Heat Shock Transcription Factors; Heat-Shock Proteins; Huntingtin Protein; Huntington Disease; Mice; Mitochondria; Nerve Tissue Proteins; Neuroblastoma; Neuroprotective Agents; Nuclear Proteins; PPAR gamma; Proteasome Endopeptidase Complex; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Ubiquitin; Up-Regulation

2015
Rosiglitazone protects rat liver against acute liver injury associated with the NF-κB signaling pathway.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Disease Models, Animal; Inflammation Mediators; Interleukin-6; Male; NF-kappa B; Protective Agents; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Thiazolidinediones; Tumor Necrosis Factor-alpha

2016
Resolution of Inflammation by Resolvin D1 Is Essential for Peroxisome Proliferator-activated Receptor-γ-mediated Analgesia during Postincisional Pain Development in Type 2 Diabetes.
    Anesthesiology, 2015, Volume: 123, Issue:6

    Topics: Analgesia; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Docosahexaenoic Acids; Hypoglycemic Agents; Inflammation; Macrophages; Male; Mice; Pain, Postoperative; PPAR gamma; Rosiglitazone; Thiazolidinediones

2015
A PPARγ AGONIST ENHANCES BACTERIAL CLEARANCE THROUGH NEUTROPHIL EXTRACELLULAR TRAP FORMATION AND IMPROVES SURVIVAL IN SEPSIS.
    Shock (Augusta, Ga.), 2016, Volume: 45, Issue:4

    Topics: Anilides; Animals; Disease Models, Animal; Escherichia coli; Extracellular Traps; Male; Mice; Neutrophils; PPAR gamma; Rosiglitazone; Sepsis; Signal Transduction; Thiazolidinediones

2016
Depression mediates impaired glucose tolerance and cognitive dysfunction: A neuromodulatory role of rosiglitazone.
    Hormones and behavior, 2016, Volume: 78

    Topics: Animals; Behavior, Animal; Blood Glucose; Cognition Disorders; Depression; Disease Models, Animal; Hippocampus; Hypoglycemic Agents; Insulin; Male; Mice; Rosiglitazone; Stress, Psychological; Thiazolidinediones

2016
Developmental Programming: Impact of Gestational Steroid and Metabolic Milieus on Adiposity and Insulin Sensitivity in Prenatal Testosterone-Treated Female Sheep.
    Endocrinology, 2016, Volume: 157, Issue:2

    Topics: Adiposity; Animals; Disease Models, Animal; Embryonic Development; Female; Flutamide; Insulin Resistance; Obesity; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Rosiglitazone; Sheep; Testosterone; Thiazolidinediones

2016
Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone.
    Journal of immunology (Baltimore, Md. : 1950), 2016, Feb-01, Volume: 196, Issue:3

    Topics: Animals; Cytokines; Disease Models, Animal; Female; Fluorescent Antibody Technique; Galactosylceramides; Humans; Hypoglycemic Agents; Immunophenotyping; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Natural Killer T-Cells; PPAR gamma; Pregnancy; Premature Birth; Real-Time Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones

2016
Effect of intranasal rosiglitazone on airway inflammation and remodeling in a murine model of chronic asthma.
    The Korean journal of internal medicine, 2016, Volume: 31, Issue:1

    Topics: Actins; Administration, Inhalation; Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Chronic Disease; Collagen; Disease Models, Animal; Female; Lung; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Pneumonia; PPAR gamma; Pulmonary Eosinophilia; Rosiglitazone; Signal Transduction; Thiazolidinediones; Toll-Like Receptor 4

2016
A PPAR-gamma agonist attenuates pulmonary injury induced by irradiation in a murine model.
    Lung cancer (Amsterdam, Netherlands), 2015, Volume: 90, Issue:3

    Topics: Animals; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Humans; Lung Injury; Mice; PPAR gamma; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiation, Ionizing; Radiotherapy; Rosiglitazone; Thiazolidinediones; Tomography, X-Ray Computed; Xenograft Model Antitumor Assays

2015
Activation of PPARγ Ameliorates Spatial Cognitive Deficits through Restoring Expression of AMPA Receptors in Seipin Knock-Out Mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Jan-27, Volume: 36, Issue:4

    Topics: Animals; Cognition Disorders; CREB-Binding Protein; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; GTP-Binding Protein gamma Subunits; Heterotrimeric GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Maze Learning; Mice; Mice, Knockout; Patch-Clamp Techniques; PPAR gamma; Receptors, AMPA; Rosiglitazone; Spatial Behavior; Swimming; Thiazolidinediones

2016
An M1-like Macrophage Polarization in Decidual Tissue during Spontaneous Preterm Labor That Is Attenuated by Rosiglitazone Treatment.
    Journal of immunology (Baltimore, Md. : 1950), 2016, Mar-15, Volume: 196, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cell Separation; Decidua; Disease Models, Animal; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunophenotyping; Macrophages; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Obstetric Labor, Premature; PPAR gamma; Pregnancy; Real-Time Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones

2016
Concomitant use of rapamycin and rosiglitazone delays the progression of polycystic kidney disease in Han:SPRD rats: a study of the mechanism of action.
    American journal of physiology. Renal physiology, 2018, 05-01, Volume: 314, Issue:5

    Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Epithelial Cells; Fibrosis; G1 Phase Cell Cycle Checkpoints; Humans; Kidney; Lipids; Male; Phosphorylation; Polycystic Kidney, Autosomal Dominant; PPAR gamma; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Renal Agents; Ribosomal Protein S6 Kinases, 70-kDa; Rosiglitazone; Signal Transduction; Sirolimus

2018
Adipose tissue deficiency results in severe hyperlipidemia and atherosclerosis in the low-density lipoprotein receptor knockout mice.
    Biochimica et biophysica acta, 2016, Volume: 1861, Issue:5

    Topics: Adipose Tissue; Adiposity; Animals; Atherosclerosis; Cholesterol; Diet, High-Fat; Disease Models, Animal; Genetic Predisposition to Disease; GTP-Binding Protein gamma Subunits; Heterotrimeric GTP-Binding Proteins; Hyperlipidemias; Hypolipidemic Agents; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Receptors, LDL; Rosiglitazone; Severity of Illness Index; Thiazolidinediones; Time Factors

2016
Short-term treatment with a 2-carba analog of cyclic phosphatidic acid induces lowering of plasma cholesterol levels in ApoE-deficient mice.
    Biochemical and biophysical research communications, 2016, Apr-22, Volume: 473, Issue:1

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Carotid Arteries; Cholesterol, LDL; Disease Models, Animal; Disease Progression; Inflammation; Lipid Metabolism; Macrophages; Mice; Mice, Inbred BALB C; Mice, Knockout; Phosphatidic Acids; PPAR gamma; Real-Time Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Triglycerides

2016
Minimally invasive surgery for ICH evacuation followed by rosiglitazone infusion therapy increased perihematomal PPARγ expression and improved neurological outcomes in rabbits.
    Neurological research, 2016, Volume: 38, Issue:3

    Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Cerebral Hemorrhage; Disease Models, Animal; Fibrinolytic Agents; Gene Expression Regulation; Male; Minimally Invasive Surgical Procedures; Nervous System Diseases; Permeability; PPAR gamma; Rabbits; Rosiglitazone; Thiazolidinediones; Tomography Scanners, X-Ray Computed

2016
Effect of Vanadyl Rosiglitazone, a New Insulin-Mimetic Vanadium Complexes, on Glucose Homeostasis of Diabetic Mice.
    Applied biochemistry and biotechnology, 2016, Volume: 180, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Drinking Behavior; Feeding Behavior; Homeostasis; Insulin; Male; Metformin; Mice; Quercetin; Rosiglitazone; Spectrophotometry, Infrared; Thiazolidinediones; Trehalose; Vanadium

2016
Altered pharmacokinetics of rosiglitazone in a mouse model of non-alcoholic fatty liver disease.
    Drug metabolism and personalized therapy, 2016, 09-01, Volume: 31, Issue:3

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; High Fructose Corn Syrup; Male; Mice; Non-alcoholic Fatty Liver Disease; Rosiglitazone; Thiazolidinediones

2016
Cardioprotective role of peroxisome proliferator-activated receptor-γ agonist, rosiglitazone in a unique murine model of diabetic cardiopathy.
    Life sciences, 2016, Oct-01, Volume: 162

    Topics: Animals; Aorta; Diabetes Complications; Disease Models, Animal; Gene Expression; Heart Failure; Hypoglycemic Agents; Kidney; Mice; Myocardium; PPAR gamma; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones

2016
Developmental Programming: Insulin Sensitizer Prevents the GnRH-Stimulated LH Hypersecretion in a Sheep Model of PCOS.
    Endocrinology, 2016, Volume: 157, Issue:12

    Topics: Androgen Antagonists; Androgens; Animals; Disease Models, Animal; Estrogen Receptor alpha; Female; Flutamide; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Luteinizing Hormone, beta Subunit; Pituitary Gland; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Insulin; Receptors, Androgen; Rosiglitazone; Sheep; Testosterone; Thiazolidinediones

2016
FAK signalling controls insulin sensitivity through regulation of adipocyte survival.
    Nature communications, 2017, 02-06, Volume: 8

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Adiposity; Adult; Animals; Apoptosis; Cell Survival; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Female; Focal Adhesion Kinase 1; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Middle Aged; Obesity; PPAR gamma; Primary Cell Culture; Rosiglitazone; Signal Transduction; Thiazolidinediones

2017
Thiazolidinediones abrogate cervical cancer growth.
    Experimental cell research, 2017, 04-15, Volume: 353, Issue:2

    Topics: Animals; Cell Differentiation; Cell Proliferation; Complement Factor D; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Mice; Papillomaviridae; Pioglitazone; PPAR gamma; Rosiglitazone; Thiazolidinediones; Uterine Cervical Neoplasms

2017
Rosiglitazone improves aortic arginine transport, through inhibition of PKCalpha, in uremic rats.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:2

    Topics: Animals; Aorta; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Disease Models, Animal; Hypoglycemic Agents; Kidney Failure, Chronic; Male; Nitric Oxide; Protein Kinase C-alpha; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Uremia

2008
Different effect of acute treatment with rosiglitazone on rat myocardial ischemia/reperfusion injury by administration method.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: Acetylcysteine; Animals; Antioxidants; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; I-kappa B Proteins; Infusions, Intravenous; Injections, Intravenous; Male; Models, Biological; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Peroxidase; Phosphorylation; PPAR gamma; Protective Agents; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2008
The effects of peroxisome proliferator-activated receptor-gamma agonist on a murine model of experimental allergic rhinitis.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2008, Volume: 139, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Immunoglobulin E; Immunohistochemistry; Mice; Mice, Inbred BALB C; Ovalbumin; PPAR gamma; Rhinitis, Allergic, Perennial; Rosiglitazone; Thiazolidinediones

2008
Rosiglitazone attenuates the cognitive deficits induced by high fat diet feeding in rats.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: Animals; Behavior, Animal; Blood Glucose; Cognition; Dietary Fats; Disease Models, Animal; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Maze Learning; Memory; Motor Activity; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Time Factors

2008
Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality.
    PloS one, 2008, Jul-09, Volume: 3, Issue:7

    Topics: Animals; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Echocardiography; Gene Expression Profiling; Insulin; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Rosiglitazone; Thiazolidinediones

2008
Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:4

    Topics: Albuminuria; Animals; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Hypoglycemic Agents; Male; Mice; Mice, Inbred DBA; Oxidative Stress; Podocytes; Rosiglitazone; Spectrometry, Mass, Electrospray Ionization; Thiazolidinediones; Urine

2008
Effects of rosiglitazone (a peroxysome proliferator-activated receptor gamma agonist) on the blood pressure and aortic structure in metabolically programmed (perinatal low protein) rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:5

    Topics: Animals; Aorta; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Diet, Protein-Restricted; Disease Models, Animal; Elasticity; Female; Hypertension; Hypertrophy; Insulin; Leptin; Male; Nitric Oxide Synthase Type III; PPAR gamma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Rosiglitazone; Thiazolidinediones; Tunica Media

2008
Zinc deficiency induces vascular pro-inflammatory parameters associated with NF-kappaB and PPAR signaling.
    Journal of the American College of Nutrition, 2008, Volume: 27, Issue:5

    Topics: Animals; Atherosclerosis; Caffeic Acids; Cell Adhesion; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Inflammation; Male; Mice; Monocytes; NF-kappa B; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Phenylethyl Alcohol; Receptors, LDL; Rosiglitazone; Thiazolidinediones; Zinc

2008
Myocardial heat shock protein 60 expression in insulin-resistant and diabetic rats.
    The Journal of endocrinology, 2009, Volume: 200, Issue:2

    Topics: Amlodipine; Animals; Antihypertensive Agents; Chaperonin 60; Diabetes Mellitus, Experimental; Disease Models, Animal; Fructose; Gene Expression; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin Resistance; Male; Myocardium; Rats; Rats, Sprague-Dawley; Rosiglitazone; Streptozocin; Thiazolidinediones

2009
Rescue of neurons from ischemic injury by peroxisome proliferator-activated receptor-gamma requires a novel essential cofactor LMO4.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Nov-19, Volume: 28, Issue:47

    Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Embryo, Mammalian; Gene Expression Regulation; Glucose; Homeodomain Proteins; Hypoglycemic Agents; Immunoprecipitation; Infarction, Middle Cerebral Artery; Kainic Acid; LIM Domain Proteins; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Oxygen; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Rosiglitazone; Signal Transduction; Superoxide Dismutase; Thiazolidinediones; Trans-Activators; Transcription Factors

2008
Antiatherosclerotic effect of farnesoid X receptor.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:2

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cardiovascular Agents; CD11b Antigen; CD36 Antigens; Chenodeoxycholic Acid; Disease Models, Animal; DNA-Binding Proteins; Female; Humans; Hyperlipidemias; Interleukin-1beta; Interleukin-6; Ligands; Lipids; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Sterol Regulatory Element Binding Protein 1; Thiazolidinediones; Toll-Like Receptor 4; Transcription Factors; Tumor Necrosis Factor-alpha

2009
Hematoma resolution as a therapeutic target: the role of microglia/macrophages.
    Stroke, 2009, Volume: 40, Issue:3 Suppl

    Topics: Animals; Apoptosis; Catalase; CD36 Antigens; Cerebral Hemorrhage; Disease Models, Animal; Erythrocytes; Hematoma; Humans; Macrophages; Mice; Microglia; Phagocytosis; PPAR gamma; Rosiglitazone; Thiazolidinediones

2009
Distinct functions of vascular endothelial and smooth muscle PPARgamma in regulation of blood pressure and vascular tone.
    Toxicologic pathology, 2009, Volume: 37, Issue:1

    Topics: Animals; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Femoral Artery; Hypertension; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; PPAR gamma; Rosiglitazone; Thiazolidinediones; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2009
Inhibition of hepatic interleukin-18 production by rosiglitazone in a rat model of nonalcoholic fatty liver disease.
    World journal of gastroenterology, 2008, Dec-21, Volume: 14, Issue:47

    Topics: Animals; Caspase 1; Disease Models, Animal; Fatty Liver; Hypoglycemic Agents; Insulin Resistance; Interleukin-18; Liver; Male; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones

2008
The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin.
    Journal of immunology (Baltimore, Md. : 1950), 2009, Jan-01, Volume: 182, Issue:1

    Topics: Adiponectin; Animals; Atherosclerosis; Disease Models, Animal; Female; Inflammation Mediators; Lupus Erythematosus, Systemic; Male; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, Knockout; PPAR gamma; Rosiglitazone; Thiazolidinediones

2009
Capillary endothelial but not lymphatic function is restored under rosiglitazone in Zucker diabetic fatty rats.
    Microvascular research, 2009, Volume: 77, Issue:2

    Topics: Albumins; Animals; Capillaries; Capillary Permeability; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium; Lymphatic System; Male; Obesity; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factor A

2009
Rosiglitazone treatment attenuates renal tissue inflammation generated by urinary tract obstruction.
    Nephrology (Carlton, Vic.), 2009, Volume: 14, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Immunohistochemistry; Interleukin-10; Interleukin-4; Interleukin-6; Kidney; Male; Nitric Oxide; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Transforming Growth Factor beta; Ureteral Obstruction

2009
Regulation of angiotensin II type I receptor (AT1R) protein levels in the obese Zucker rat kidney and urine.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Hypoglycemic Agents; Kidney; Metabolic Syndrome; Obesity; PPAR gamma; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Rosiglitazone; Sodium Chloride, Dietary; Tetrazoles; Thiazolidinediones; Thinness

2009
Rosiglitazone decreases blood pressure and renal injury in a female mouse model of systemic lupus erythematosus.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:4

    Topics: Albuminuria; Animals; Antihypertensive Agents; Blood Pressure; Chemokine CCL2; Disease Models, Animal; Endothelin-1; Female; Hypertension; Kidney; Kidney Diseases; Lupus Erythematosus, Systemic; Macrophages; Mice; Monocytes; Osteopontin; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones

2009
New mechanism of rosiglitazone to reduce neointimal hyperplasia: activation of glycogen synthase kinase-3beta followed by inhibition of MMP-9.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:4

    Topics: Animals; Apoptosis; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Extracellular Signal-Regulated MAP Kinases; Gene Transfer Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperplasia; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; NF-kappa B; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Thiazolidinediones; Tunica Intima

2009
Additive action of 11beta-HSD1 inhibition and PPAR-gamma agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats.
    International journal of obesity (2005), 2009, Volume: 33, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiponectin; Animals; Disease Models, Animal; Fatty Liver; Male; Obesity; PPAR gamma; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Rosiglitazone; Thiazolidinediones; Triazoles; Triglycerides

2009
Rosiglitazone protects diabetic rats against kidney injury through the suppression of renal matrix metalloproteinase-9 expression.
    Diabetes, obesity & metabolism, 2009, Volume: 11, Issue:5

    Topics: Albuminuria; Animals; Case-Control Studies; Diabetes Mellitus, Experimental; Disease Models, Animal; Hypoglycemic Agents; Kidney; Male; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Retinol-Binding Proteins; RNA, Messenger; Rosiglitazone; Thiazolidinediones

2009
Rosiglitazone attenuates the severity of sodium taurocholate-induced acute pancreatitis and pancreatitis-associated lung injury.
    Archives of medical research, 2009, Volume: 40, Issue:2

    Topics: Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Lung Injury; Male; Pancreatitis, Acute Necrotizing; Peroxidase; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Taurocholic Acid; Thiazolidinediones; Tumor Necrosis Factor-alpha

2009
PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease.
    The European journal of neuroscience, 2009, Volume: 29, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catalepsy; CD11b Antigen; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Dopamine; Drug Interactions; Dynorphins; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Globus Pallidus; Locomotion; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; PPAR gamma; Psychomotor Performance; RNA, Messenger; Rosiglitazone; Smell; Tandem Mass Spectrometry; Thiazolidinediones; Tyrosine 3-Monooxygenase

2009
Delayed post ischemic treatment with Rosiglitazone attenuates infarct volume, neurological deficits and neutrophilia after embolic stroke in rat.
    Brain research, 2009, May-19, Volume: 1271

    Topics: Animals; Brain Infarction; Brain Ischemia; Cell Death; Disease Models, Animal; DNA Fragmentation; Encephalitis; Hypoglycemic Agents; Infarction, Middle Cerebral Artery; Leukocyte Count; Male; Neuroprotective Agents; Neutrophils; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Time Factors; Treatment Outcome

2009
Insulin resistance acts as an independent risk factor exacerbating high-purine diet induced renal injury and knee joint gouty lesions.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2009, Volume: 58, Issue:10

    Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Gout; Homeostasis; Hyperuricemia; Hypoglycemic Agents; Insulin Resistance; Knee Joint; Male; Obesity; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Purines; Rats; Rats, Inbred OLETF; Risk Factors; Rosiglitazone; Thiazolidinediones; Uric Acid

2009
Thiazolidinediones: antidiabetic agents with effects on bone.
    Joint bone spine, 2009, Volume: 76, Issue:3

    Topics: Aged; Animals; Bone and Bones; Bone Density; Bone Resorption; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Male; Mice; Osteoporosis; Pioglitazone; Randomized Controlled Trials as Topic; Rats; Rosiglitazone; Thiazolidinediones

2009
Ameliorative potential of rosiglitazone in tibial and sural nerve transection-induced painful neuropathy in rats.
    Pharmacological research, 2009, Volume: 59, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cold Temperature; Disease Models, Animal; Hot Temperature; Oxidative Stress; Pain Measurement; Peroxidase; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Sciatic Neuropathy; Sural Nerve; Thiazolidinediones; Thiobarbituric Acid Reactive Substances; Tibial Nerve

2009
Activation of PPARgamma by rosiglitazone attenuates intestinal Cl- secretion.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:1

    Topics: Administration, Oral; Animals; Calcium; Carbachol; Chlorides; Cholera Toxin; Colforsin; Colon; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Disease Models, Animal; Electric Impedance; Female; Gastrointestinal Agents; HT29 Cells; Humans; Ileum; Intermediate-Conductance Calcium-Activated Potassium Channels; Intestinal Mucosa; Intestinal Secretions; Intestines; Jejunum; KCNQ1 Potassium Channel; Mice; Pioglitazone; PPAR gamma; Rosiglitazone; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Thiazolidinediones; Time Factors

2009
PPARgamma agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway.
    Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:8

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cell Survival; Cells, Cultured; Disease Models, Animal; Gene Expression; Gene Silencing; Hypoglycemic Agents; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Rosiglitazone; Signal Transduction; Thiazolidinediones; Toll-Like Receptor 4; Vasculitis

2009
PAR-1622 is a selective peroxisome proliferator-activated receptor gamma partial activator with preserved antidiabetic efficacy and broader safety profile for fluid retention.
    Archives of pharmacal research, 2009, Volume: 32, Issue:5

    Topics: Adipogenesis; Administration, Oral; Animals; Blood Glucose; Blood Volume; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Partial Agonism; Genes, Reporter; Humans; Hypoglycemic Agents; Isoxazoles; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred ICR; PPAR gamma; Propionates; Rosiglitazone; Thiazolidinediones; Thiophenes; Transfection; Water-Electrolyte Balance

2009
Adiponectin deficiency promotes the production of inflammatory mediators while severely exacerbating hepatic injury in mice with polymicrobial sepsis.
    The Journal of surgical research, 2010, Jun-15, Volume: 161, Issue:2

    Topics: Adiponectin; Alanine Transaminase; Animals; Disease Models, Animal; Fibrinolytic Agents; Inflammation; Inflammation Mediators; Interleukin-6; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Punctures; Receptors, CCR2; Rosiglitazone; Sepsis; Shock, Septic; Thiazolidinediones; Tumor Necrosis Factor-alpha

2010
Peroxisome proliferator-activated receptor-g agonist treatment increases septation and angiogenesis and decreases airway hyperresponsiveness in a model of experimental neonatal chronic lung disease.
    Anatomical record (Hoboken, N.J. : 2007), 2009, Volume: 292, Issue:7

    Topics: Animals; Animals, Newborn; Bronchoconstriction; Cell Differentiation; Disease Models, Animal; Fibroblasts; Humans; Hyperoxia; Infant, Newborn; Infant, Newborn, Diseases; Lung; Lung Diseases; Mice; Mice, Inbred C57BL; Muscle, Smooth; Neovascularization, Physiologic; PPAR gamma; Respiratory System; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Vasodilator Agents

2009
Rosiglitazone reduces the development and rupture of experimental aortic aneurysms.
    Circulation, 2009, Jun-23, Volume: 119, Issue:24

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Blood Glucose; Body Weight; Cholesterol; Disease Models, Animal; E-Selectin; Humans; Hypercholesterolemia; Hypoglycemic Agents; Interleukin-6; Mice; Mice, Knockout; PPAR gamma; Receptors, Angiotensin; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2009
Rosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse model.
    American journal of respiratory cell and molecular biology, 2010, Volume: 42, Issue:4

    Topics: Animals; Blood Pressure; Cell Proliferation; Chronic Disease; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Humans; Hypertension, Pulmonary; Hypoxia; Ligands; Male; Mice; NADPH Oxidase 4; NADPH Oxidases; Organ Size; PPAR gamma; PTEN Phosphohydrolase; Receptor, Platelet-Derived Growth Factor beta; Rosiglitazone; Signal Transduction; Superoxides; Thiazolidinediones; Vasodilator Agents

2010
Antidiabetic effects of 11beta-HSD1 inhibition in a mouse model of combined diabetes, dyslipidaemia and atherosclerosis.
    Diabetes, obesity & metabolism, 2009, Volume: 11, Issue:7

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Atherosclerosis; Blood Glucose; Body Composition; Body Weight; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Dyslipidemias; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin; Male; Metabolic Syndrome; Mice; Mice, Knockout; Rosiglitazone; Simvastatin; Thiazolidinediones; Triglycerides

2009
Functional significance of skeletal muscle adiponectin production, changes in animal models of obesity and diabetes, and regulation by rosiglitazone treatment.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:3

    Topics: Adiponectin; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Obese; Muscle, Skeletal; Obesity; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2009
Rosiglitazone alone or in combination with tissue plasminogen activator improves ischemic brain injury in an embolic model in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009, Volume: 29, Issue:10

    Topics: Animals; Brain Ischemia; Collagen Type IV; Disease Models, Animal; Drug Therapy, Combination; Embolism; Hypoglycemic Agents; Matrix Metalloproteinase 9; Middle Cerebral Artery; Neuroprotective Agents; PPAR gamma; Rats; Rosiglitazone; Thiazolidinediones; Tissue Plasminogen Activator; Treatment Outcome

2009
[The effect of rosiglitazone on the activity of STAT1 in rats with severe acute pancreatitis].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2009, Feb-01, Volume: 47, Issue:3

    Topics: Acute Disease; Animals; Disease Models, Animal; Male; Pancreas; Pancreatitis; Random Allocation; Rats; Rats, Wistar; Rosiglitazone; STAT1 Transcription Factor; Thiazolidinediones

2009
Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease.
    Molecular psychiatry, 2010, Volume: 15, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Brain; Disease Models, Animal; Inflammation; Lithium Compounds; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Nerve Degeneration; Nerve Tissue Proteins; Presenilin-1; Rosiglitazone; Signal Transduction; Thiazolidinediones; Wnt Proteins

2010
Peroxisome proliferator-activated receptor gamma agonist down-regulates IL-17 expression in a murine model of allergic airway inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2009, Sep-01, Volume: 183, Issue:5

    Topics: Animals; Asthma; Disease Models, Animal; Down-Regulation; Female; Inflammation Mediators; Interleukin-17; Lung; Mice; Mice, Inbred C57BL; NF-kappa B; Ovalbumin; Pioglitazone; PPAR gamma; Recombinant Proteins; Rosiglitazone; Signal Transduction; Thiazolidinediones

2009
PPAR-gamma agonist rosiglitazone reverses increased cerebral venous hydraulic conductivity during hypertension.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:4

    Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Brain Edema; Capillary Permeability; Cerebral Veins; Cerebrovascular Circulation; Chronic Disease; Cyclic N-Oxides; Disease Models, Animal; Female; Hydrostatic Pressure; Hypertension; NG-Nitroarginine Methyl Ester; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Spin Labels; Thiazolidinediones; Time Factors

2009
Mechanisms of adipose tissue redistribution with rosiglitazone treatment in various adipose depots.
    Metabolism: clinical and experimental, 2010, Volume: 59, Issue:1

    Topics: Adiposity; Animals; Base Sequence; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; DNA Primers; Energy Metabolism; Gene Expression Profiling; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Lipids; Rats; Rats, Long-Evans; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones

2010
Artemisia capillaris inhibits lipid accumulation in 3T3-L1 adipocytes and obesity in C57BL/6J mice fed a high fat diet.
    Journal of medicinal food, 2009, Volume: 12, Issue:4

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Artemisia; Carnitine O-Palmitoyltransferase; Cell Line; Diet; Dietary Fats; Disease Models, Animal; Fatty Acids, Nonesterified; Flavonoids; Glycerolphosphate Dehydrogenase; Hypolipidemic Agents; Leptin; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Obesity; Phenols; Phytotherapy; Plant Extracts; PPAR gamma; Rosiglitazone; Thiazolidinediones; Triglycerides

2009
Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests.
    Behavioural pharmacology, 2009, Volume: 20, Issue:7

    Topics: Anilides; Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Models, Animal; Drug Evaluation, Preclinical; Immobility Response, Tonic; Male; Mice; Motor Activity; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Swimming; Thiazolidinediones

2009
Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension.
    Circulation research, 2009, Oct-23, Volume: 105, Issue:9

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Antioxidants; Blood Pressure; Blood Vessels; Catalase; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Homeostasis; Humans; Hydrogen Peroxide; Hypertension; Imidazoles; Ion Channels; Male; Medulla Oblongata; Microinjections; Mitochondria; Mitochondrial Proteins; NADPH Oxidases; Onium Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Rosiglitazone; Spin Labels; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Sympathetic Nervous System; Thiazolidinediones; Time Factors; Transcription Factors; Transcriptional Activation; Transduction, Genetic; Uncoupling Protein 2; Up-Regulation

2009
A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:6

    Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acetyl Coenzyme A; Animals; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Models, Animal; Hypoglycemic Agents; Lysophosphatidylcholines; Male; Mice; Platelet Activating Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transfection

2009
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats.
    Journal of lipid research, 2010, Volume: 51, Issue:4

    Topics: Animals; Chenodeoxycholic Acid; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Male; Muscle, Skeletal; Obesity; Phosphorylation; Random Allocation; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors

2010
In vivo metabolic phenotyping of myocardial substrate metabolism in rodents: differential efficacy of metformin and rosiglitazone monotherapy.
    Circulation. Cardiovascular imaging, 2009, Volume: 2, Issue:5

    Topics: Animals; Biological Transport; Diabetes Mellitus, Type 2; Disease Models, Animal; Echocardiography; Energy Metabolism; Fatty Acids; Gene Expression Regulation; Glucose; Glucose Transport Proteins, Facilitative; Heart Diseases; Hemodynamics; Hypoglycemic Agents; Male; Metformin; Myocardium; Oxidation-Reduction; Phenotype; Positron-Emission Tomography; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones; Time Factors

2009
A randomised controlled trial on melatonin and rosiglitazone for prevention of adhesion formation in a rat uterine horn model.
    Archives of gynecology and obstetrics, 2010, Volume: 282, Issue:1

    Topics: Administration, Oral; Animals; Antioxidants; Disease Models, Animal; Female; Injections, Intraperitoneal; Melatonin; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Tissue Adhesions; Uterine Diseases; Uterus

2010
12/15-Lipoxygenase inhibitor baicalein suppresses PPAR gamma expression and nuclear translocation induced by cerebral ischemia/reperfusion.
    Brain research, 2010, Jan-11, Volume: 1307

    Topics: Anilides; Animals; Antioxidants; Cell Nucleus; Cerebral Cortex; Cytosol; Disease Models, Animal; Flavanones; Hypoglycemic Agents; Infarction, Middle Cerebral Artery; Male; PPAR gamma; Protein Transport; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rosiglitazone; Thiazolidinediones; Time Factors; Up-Regulation

2010
Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema.
    Neuropharmacology, 2010, Volume: 58, Issue:2

    Topics: Anilides; Animals; Benzhydryl Compounds; Brain; Central Nervous System Agents; Disease Models, Animal; Edema; Epoxy Compounds; Gene Expression; Inflammation; Male; Pain; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rosiglitazone; Spinal Cord; Thiazolidinediones

2010
Peroxisome proliferator-activated receptor-gamma activation attenuates cardiac fibrosis in type 2 diabetic rats: the effect of rosiglitazone on myocardial expression of receptor for advanced glycation end products and of connective tissue growth factor.
    Basic research in cardiology, 2010, Volume: 105, Issue:3

    Topics: Animals; Body Weight; Cardiomyopathies; Connective Tissue Growth Factor; Diabetes Mellitus, Type 2; Disease Models, Animal; Echocardiography; Fibrosis; Glucose Tolerance Test; Male; Myocardium; PPAR gamma; Rats; Rats, Inbred OLETF; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Rosiglitazone; Thiazolidinediones

2010
[Study on the protective effect and related mechanisms of Rosiglitazone on acute hepatic failure in mice].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:7

    Topics: Acute Disease; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2009
Countervailing vascular effects of rosiglitazone in high cardiovascular risk mice: role of oxidative stress and PRMT-1.
    Clinical science (London, England : 1979), 2010, Feb-09, Volume: 118, Issue:9

    Topics: Animals; Carotid Artery, Internal; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Female; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Nitrites; Oxidative Stress; Protein-Arginine N-Methyltransferases; Rosiglitazone; Superoxides; Thiazolidinediones

2010
[The effect of Rosiglitazone, a PPARgamma receptor agonist, on the NF-kappaB signaling pathway in acute hepatic injury induced by LPS].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:12

    Topics: Acute Disease; Animals; Blotting, Western; Disease Models, Animal; I-kappa B Proteins; Injections, Intraperitoneal; Lipopolysaccharides; Liver; Liver Diseases; Male; Mice; NF-kappa B; NF-kappa B p50 Subunit; PPAR gamma; Random Allocation; Rosiglitazone; Signal Transduction; Thiazolidinediones

2009
Rosiglitazone prevents the progression of renal injury in DOCA-salt hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:3

    Topics: Animals; Cyclooxygenase 2; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Glomerulonephritis; HSP27 Heat-Shock Proteins; Hypertension; Kidney; Male; Nephritis, Interstitial; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Transforming Growth Factor beta1

2010
Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.
    Nature medicine, 2010, Volume: 16, Issue:3

    Topics: Animals; Bicarbonates; Carbonic Anhydrase II; Carbonic Anhydrase IV; Colon; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Disease Models, Animal; Female; Gene Expression; Hypoglycemic Agents; Male; Mice; Mice, Inbred CFTR; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones

2010
Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury.
    Cardiovascular research, 2010, Aug-01, Volume: 87, Issue:3

    Topics: Anilides; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Northern; Blotting, Western; Caspase 3; Cell Line; Cell Survival; Disease Models, Animal; Down-Regulation; Gene Expression Profiling; Mice; MicroRNAs; Myeloid Cell Leukemia Sequence 1 Protein; Myocardial Reperfusion Injury; Myocardium; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Phosphorylation; Pioglitazone; PPAR gamma; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rosiglitazone; Thiazolidinediones; Time Factors; Transfection

2010
Lipids control mucus production in cystic fibrosis.
    Nature medicine, 2010, Volume: 16, Issue:3

    Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase IV; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Disease Models, Animal; Humans; Hypoglycemic Agents; Mice; Mice, Inbred CFTR; Mucus; PPAR gamma; Rosiglitazone; Thiazolidinediones

2010
The low dose combination of fenofibrate and rosiglitazone halts the progression of diabetes-induced experimental nephropathy.
    European journal of pharmacology, 2010, Jun-25, Volume: 636, Issue:1-3

    Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Creatinine; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Drug Interactions; Fenofibrate; Kidney; Lipids; Oxidative Stress; PPAR alpha; PPAR gamma; Proteinuria; Rats; Rosiglitazone; Thiazolidinediones

2010
Ameliorative role of rosiglitazone in hyperhomocysteinemia-induced experimental cardiac hypertrophy.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:1

    Topics: Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Homocysteine; Hyperhomocysteinemia; Hypertrophy, Left Ventricular; Male; Methionine; Oxidative Stress; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2010
Oral intake of rosiglitazone promotes a central antihypertensive effect via upregulation of peroxisome proliferator-activated receptor-gamma and alleviation of oxidative stress in rostral ventrolateral medulla of spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:6

    Topics: Administration, Oral; Amlodipine; Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Heart Rate; Hypertension; Kidney Medulla; Male; Oxidative Stress; PPAR gamma; Probability; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Up-Regulation; Vasodilator Agents

2010
Systemic hyperthermia masks the neuroprotective effects of MK-801, but not rosiglitazone in brain ischaemia.
    Basic & clinical pharmacology & toxicology, 2010, Volume: 107, Issue:3

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Fever; Male; Neuroprotective Agents; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2010
Rosiglitazone promotes pancreatic regeneration in experimental model of acute pancreatitis.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:2

    Topics: Acute Disease; Animals; Arginine; Disease Models, Animal; DNA; Female; Male; Pancreatitis; PPAR gamma; Rats; Rats, Wistar; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Severity of Illness Index; Sincalide; Thiazolidinediones; Time Factors

2011
Rosiglitazone reverses endothelial dysfunction but not remodeling of femoral artery in Zucker diabetic fatty rats.
    Cardiovascular diabetology, 2010, May-19, Volume: 9

    Topics: Adiposity; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Femoral Artery; Hypoglycemic Agents; Matrix Metalloproteinase 9; Myography; Nitric Oxide Synthase Type III; Pancreatic Elastase; Rats; Rats, Zucker; Receptors, Adrenergic, alpha; Rosiglitazone; Thiazolidinediones; Time Factors; Triglycerides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2010
Rosiglitazone attenuates development of polycystic kidney disease and prolongs survival in Han:SPRD rats.
    Clinical science (London, England : 1979), 2010, Jul-09, Volume: 119, Issue:8

    Topics: Animals; Chemokine CCL2; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Drug Evaluation, Preclinical; Hypoglycemic Agents; Male; Polycystic Kidney Diseases; PPAR gamma; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Survival Analysis; Thiazolidinediones; Transforming Growth Factor beta1

2010
Rosiglitazone attenuates endothelin-1-induced vasoconstriction by upregulating endothelial expression of endothelin B receptor.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:1

    Topics: Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Chromatin Immunoprecipitation; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Humans; Hypoglycemic Agents; Immunohistochemistry; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Receptor, Endothelin B; Reverse Transcriptase Polymerase Chain Reaction; RNA; Rosiglitazone; Thiazolidinediones; Vasoconstriction; Vasodilator Agents

2010
Peroxisome proliferator-activated receptor-γ (PPAR-γ) activation confers functional neuroprotection in global ischemia.
    Neurotoxicity research, 2011, Volume: 19, Issue:3

    Topics: Animals; Disease Models, Animal; Hydrogen Peroxide; Ischemic Attack, Transient; Male; Mice; Neuroprotective Agents; Oxidative Stress; PPAR gamma; Rosiglitazone; Thiazolidinediones

2011
Rosiglitazone attenuates hypoxia-induced pulmonary arterial hypertension in rats.
    Respirology (Carlton, Vic.), 2010, Volume: 15, Issue:4

    Topics: Animals; Disease Models, Animal; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Male; PPAR gamma; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factors

2010
Renoprotection by rosiglitazone in accelerated type 2 diabetic nephropathy: Role of STAT1 inhibition and nephrin restoration.
    American journal of nephrology, 2010, Volume: 32, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Kidney; Kidney Glomerulus; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Nephrectomy; Protective Agents; Rosiglitazone; STAT1 Transcription Factor; Thiazolidinediones

2010
Increase in plasma glucose lowering action of rosiglitazone by electroacupuncture at bilateral Zusanli acupoints (ST.36) in rats.
    Journal of acupuncture and meridian studies, 2009, Volume: 2, Issue:2

    Topics: Acupuncture Points; Animals; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Disease Models, Animal; Electroacupuncture; Humans; Hypoglycemic Agents; Male; Random Allocation; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2009
Rosiglitazone reduces tau phosphorylation via JNK inhibition in the hippocampus of rats with type 2 diabetes and tau transfected SH-SY5Y cells.
    Neurobiology of disease, 2010, Volume: 40, Issue:2

    Topics: Animals; Blotting, Western; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Hypoglycemic Agents; Infant; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Neurons; Phosphorylation; Polymerase Chain Reaction; PPAR gamma; Rats; Rats, Inbred OLETF; Rosiglitazone; tau Proteins; Thiazolidinediones; Transfection; Treatment Outcome

2010
Rosiglitazone and vascular injury in hypercholesterolemic rabbits: neointimal formation assessment.
    Arquivos brasileiros de cardiologia, 2010, Volume: 95, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Disease Models, Animal; Hypercholesterolemia; Iliac Artery; Male; Neointima; Rabbits; Random Allocation; Rosiglitazone; Thiazolidinediones

2010
Extension of the neuroprotective time window for thiazolidinediones in ischemic stroke is dependent on time of reperfusion.
    Neuroscience, 2010, Oct-27, Volume: 170, Issue:3

    Topics: Animals; Behavior, Animal; Blood Pressure; Brain; Brain Ischemia; Cell Adhesion Molecules; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Infarction, Middle Cerebral Artery; Leukocytes; Male; Neuroprotective Agents; Pioglitazone; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Rosiglitazone; Stroke; Thiazolidinediones

2010
Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status.
    Behavioural brain research, 2011, Jan-01, Volume: 216, Issue:1

    Topics: Alzheimer Disease; Analysis of Variance; Animals; Area Under Curve; Association Learning; Blood Glucose; Cognition; Disease Models, Animal; Hyperinsulinism; Hypoglycemic Agents; Insulin; Memory; Mice; Mice, Transgenic; Rosiglitazone; Thiazolidinediones

2011
Viewing FOP through rosi-colored glasses.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010, Volume: 25, Issue:11

    Topics: Animals; Disease Models, Animal; Female; Humans; Middle Aged; Myositis Ossificans; Prednisone; Rosiglitazone; Thiazolidinediones

2010
The role of peroxisome proliferator-activated receptor γ, and effects of its agonist, rosiglitazone, on transient cerebral ischemic damage.
    Journal of the neurological sciences, 2011, Jan-15, Volume: 300, Issue:1-2

    Topics: Animals; Astrocytes; CA1 Region, Hippocampal; Cell Death; Disease Models, Animal; Gerbillinae; Interleukin-13; Interleukin-4; Ischemic Attack, Transient; Male; Microglia; Nerve Degeneration; Neuroprotective Agents; PPAR gamma; Reperfusion; Rosiglitazone; Thiazolidinediones

2011
PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice.
    Cardiovascular diabetology, 2010, Oct-18, Volume: 9

    Topics: Abdominal Fat; Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Benzimidazoles; Benzoates; CD3 Complex; Chemokine CXCL12; Chemotaxis; Dietary Fats; Disease Models, Animal; Inflammation; Insulin Resistance; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Rosiglitazone; T-Lymphocytes; Telmisartan; Thiazolidinediones; Time Factors

2010
Rosiglitazone improves pancreatic mitochondrial function in an animal model of dysglycemia: role of the insulin-like growth factor axis.
    Endocrine, 2010, Volume: 37, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 2; Diabetes, Gestational; Disease Models, Animal; Female; Glucose Intolerance; Hypoglycemic Agents; Insulin-Like Growth Factor I; Insulin-Secreting Cells; Mitochondria; Nicotine; Pregnancy; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2010
The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Adiponectin; Adipose Tissue; Animals; Body Weight; Dietary Fats; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2011
Improvement on lipid metabolic disorder by 3'-deoxyadenosine in high-fat-diet-induced fatty mice.
    The American journal of Chinese medicine, 2010, Volume: 38, Issue:6

    Topics: Animals; Area Under Curve; Cordyceps; Deoxyadenosines; Dietary Fats; Disease Models, Animal; Fenofibrate; Glucose; Glucose Clamp Technique; Glucose Intolerance; Insulin; Insulin Resistance; Lipid Metabolism; Lipid Metabolism Disorders; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Phytotherapy; Rosiglitazone; Thiazolidinediones; Weight Gain

2010
Comparative neuroprotective effects of methylprednisolone and rosiglitazone, a peroxisome proliferator-activated receptor-γ following spinal cord injury.
    Neurosciences (Riyadh, Saudi Arabia), 2011, Volume: 16, Issue:1

    Topics: Analysis of Variance; Animals; bcl-2-Associated X Protein; Disease Models, Animal; Gene Expression Regulation; HSP72 Heat-Shock Proteins; In Situ Nick-End Labeling; Interleukin-1beta; Male; Methylprednisolone; Motor Activity; Neuroprotective Agents; PPAR gamma; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Rosiglitazone; Spinal Cord Injuries; Thiazolidinediones; Time Factors; Tumor Necrosis Factor-alpha

2011
Vasculoprotective effects of rosiglitazone through modulating renin-angiotensin system in vivo and vitro.
    Cardiovascular diabetology, 2011, Jan-26, Volume: 10

    Topics: Angiotensin II; Animals; Aortic Diseases; Atherosclerosis; Blotting, Western; Cardiovascular Agents; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Hypercholesterolemia; Immunohistochemistry; Lipids; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Radioimmunoassay; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors

2011
Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking.
    Biological psychiatry, 2011, Apr-01, Volume: 69, Issue:7

    Topics: Adrenergic alpha-2 Receptor Antagonists; Alcohol Drinking; Alcohols; Analysis of Variance; Anilides; Animals; Behavior, Animal; Blood Glucose; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Food Preferences; Gene Expression Regulation; Hypoglycemic Agents; Male; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Self Administration; Substance Withdrawal Syndrome; Thiazolidinediones; Yohimbine

2011
Effectiveness of rosiglitazone on bleomycin-induced lung fibrosis: Assessed by micro-computed tomography and pathologic scores.
    European journal of radiology, 2012, Volume: 81, Issue:8

    Topics: Animals; Bleomycin; Disease Models, Animal; Feasibility Studies; Female; Humans; Mice; Mice, Inbred C57BL; Prognosis; Pulmonary Fibrosis; Reproducibility of Results; Rosiglitazone; Sensitivity and Specificity; Thiazolidinediones; Tomography, X-Ray Computed; Treatment Outcome

2012
Effects of chronic rosiglitazone treatment on renal handling of salt and water in rats with volume-overload congestive heart failure.
    Circulation. Heart failure, 2011, Volume: 4, Issue:3

    Topics: Animals; Disease Models, Animal; Heart Failure; Kidney Function Tests; Male; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sodium Chloride; Thiazolidinediones; Water; Water-Electrolyte Balance; Water-Electrolyte Imbalance

2011
Therapeutic potential of peroxisome proliferator-activated receptor γ agonist rosiglitazone in cerebral vasospasm after a rat experimental subarachnoid hemorrhage model.
    Journal of the neurological sciences, 2011, Jun-15, Volume: 305, Issue:1-2

    Topics: Animals; Disease Models, Animal; Male; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Subarachnoid Hemorrhage; Thiazolidinediones; Toll-Like Receptor 4; Vasodilator Agents; Vasospasm, Intracranial

2011
PPAR-gamma agonist rosiglitazone attenuates the inflammation caused by carrageenan in the mouse model of pleurisy.
    Inflammation, 2012, Volume: 35, Issue:1

    Topics: Adenosine Deaminase; Animals; Carrageenan; Cell Movement; Disease Models, Animal; Inflammation; Inflammation Mediators; Interleukin-17; Interleukin-1beta; Leukocytes, Mononuclear; Mice; Peroxidase; Pleurisy; PPAR gamma; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2012
Rosiglitazone improves spatial memory and decreases insoluble Aβ(1-42) in APP/PS1 mice.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2012, Volume: 7, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Female; Maze Learning; Memory; Mice; Neuroprotective Agents; Rosiglitazone; Thiazolidinediones

2012
Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: AMP-Activated Protein Kinases; Anilides; Animals; Cardiotonic Agents; Disease Models, Animal; Drug Administration Schedule; Enzyme Activation; Injections, Intravenous; JNK Mitogen-Activated Protein Kinases; Male; Mice; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phosphorylation; PPAR gamma; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Rosiglitazone; Signal Transduction; Thiazolidinediones; Time Factors; Ventricular Function, Left; Ventricular Pressure

2011
Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats.
    The Journal of endocrinology, 2011, Volume: 210, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Diabetic Nephropathies; Disease Models, Animal; Enalapril; Humans; Hypoglycemic Agents; Kidney; Liver; Male; Metabolic Syndrome; Myocardium; Obesity; PPAR gamma; Rats; Rosiglitazone; Thiazolidinediones

2011
The inhibitory effect of celecoxib and rosiglitazone on experimental endometriosis.
    Fertility and sterility, 2011, Volume: 96, Issue:2

    Topics: Analysis of Variance; Animals; Antigens, CD34; Apoptosis; Celecoxib; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Endometriosis; Female; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; PPAR gamma; Proliferating Cell Nuclear Antigen; Pyrazoles; Rosiglitazone; Sulfonamides; Thiazolidinediones; Time Factors; Uterus

2011
Effect of silybin on high-fat-induced fatty liver in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2011, Volume: 44, Issue:7

    Topics: Animals; Antioxidants; Dietary Fats; Disease Models, Animal; Drug Evaluation, Preclinical; Fatty Liver; Homeostasis; Hypoglycemic Agents; Insulin Resistance; Lipid Peroxidation; Lipids; Liver; Male; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Rosiglitazone; Silybin; Silymarin; Thiazolidinediones

2011
Pharmacological investigations on potential of peroxisome proliferator-activated receptor-gamma agonists in hyperhomocysteinemia-induced vascular dementia in rats.
    Neuroscience, 2011, Sep-29, Volume: 192

    Topics: Animals; Dementia, Vascular; Disease Models, Animal; Hyperhomocysteinemia; Hypoglycemic Agents; Male; Maze Learning; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2011
Rosiglitazone decreases peroxisome proliferator receptor-γ levels in microglia and inhibits TNF-α production: new evidences on neuroprotection in a progressive Parkinson's disease model.
    Neuroscience, 2011, Oct-27, Volume: 194

    Topics: Animals; Disease Models, Animal; Disease Progression; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Parkinsonian Disorders; PPAR gamma; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2011
Effects of pioglitazone and rosiglitazone on vascular function of mesenteric resistance arteries in rat genetic hypertension.
    Pharmacology, 2011, Volume: 88, Issue:1-2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Epinephrine; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Hypoglycemic Agents; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rosiglitazone; Thiazolidinediones; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

2011
PPARγ attenuates intimal hyperplasia by inhibiting TLR4-mediated inflammation in vascular smooth muscle cells.
    Cardiovascular research, 2011, Dec-01, Volume: 92, Issue:3

    Topics: Animals; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Cells, Cultured; Disaccharides; Disease Models, Animal; Hyperplasia; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; PPAR gamma; RNA Interference; Rosiglitazone; Sugar Phosphates; Thiazolidinediones; Toll-Like Receptor 4; Transfection; Tunica Intima

2011
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation.
    Nature, 2011, Sep-04, Volume: 477, Issue:7365

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Animals; Biphenyl Compounds; Body Fluids; Chlorocebus aethiops; COS Cells; Cyclin-Dependent Kinase 5; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Hypoglycemic Agents; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Models, Molecular; Obesity; Osteogenesis; Phosphorylation; Phosphoserine; PPAR gamma; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Tumor Necrosis Factor-alpha; Weight Gain

2011
PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease.
    Neurobiology of disease, 2012, Volume: 45, Issue:1

    Topics: Animals; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Energy Metabolism; Huntington Disease; Male; Mice; Mice, Transgenic; Mitochondria; PPAR gamma; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones; Trinucleotide Repeat Expansion

2012
The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:3

    Topics: Analysis of Variance; Animals; Astrocytes; Benzamides; Cell Count; Cognition Disorders; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutathione; Glutathione Disulfide; Hippocampus; Lithium Chloride; Male; Maze Learning; Oxidative Stress; Pilocarpine; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley; Rosiglitazone; Status Epilepticus; Systole; Thiazolidinediones

2012
Pharmacological modulation of peritoneal injury induced by dialysis fluids: is it an option?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:2

    Topics: Animals; Celecoxib; Dialysis Solutions; Disease Models, Animal; Enalapril; Female; Humans; Male; Mice; Peritoneal Dialysis; Peritoneal Diseases; Peritoneum; Pharmaceutical Preparations; Prospective Studies; Pyrazoles; Rats; Rosiglitazone; Sensitivity and Specificity; Sulfonamides; Thiazolidinediones

2012
Postnatal rosiglitazone administration to neonatal rat pups does not alter the young adult metabolic phenotype.
    Neonatology, 2012, Volume: 101, Issue:3

    Topics: Animals; Animals, Newborn; Biomarkers; Clinical Chemistry Tests; Disease Models, Animal; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Resistance; Lung; Metabolic Networks and Pathways; Phenotype; PPAR gamma; Rats; Rosiglitazone; Thiazolidinediones

2012
Rosiglitazone ameliorates the histological parameters of the dorsal root ganglion and functional assessment after sciatic nerve injury in the rat.
    Acta neurochirurgica, 2012, Volume: 154, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sciatic Neuropathy; Thiazolidinediones

2012
Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Animals; Catheterization; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Infusions, Intra-Arterial; Lipoproteins; Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; Muscle, Smooth, Vascular; Paclitaxel; Phosphorylation; PPAR gamma; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Sirolimus; Thiazolidinediones; Thromboplastin; Umbilical Arteries

2011
PPAR-γ agonists, mainly 15d-PGJ(2), reduce eosinophil recruitment following allergen challenge.
    Cellular immunology, 2012, Volume: 273, Issue:1

    Topics: Allergens; Animals; Cell Movement; Cell Proliferation; Disease Models, Animal; Eosinophilia; Eosinophils; Flow Cytometry; Immunoglobulin E; Inflammation; Interleukins; Leukocyte Count; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones

2012
Modeling disease progression and rosiglitazone intervention in type 2 diabetic Goto-Kakizaki rats.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:3

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Glucose Tolerance Test; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Male; Random Allocation; Rats; Rosiglitazone; Thiazolidinediones

2012
Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson's disease.
    Experimental neurology, 2012, Volume: 235, Issue:2

    Topics: Anilides; Animals; Antioxidants; Cell Line, Tumor; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; PPAR gamma; Rosiglitazone; Thiazolidinediones

2012
Metabonomic investigation on the protective effects of rosiglitazone and caloric restriction for renal senescence in a rat model.
    Aging clinical and experimental research, 2012, Volume: 24, Issue:5

    Topics: Animals; Antioxidants; beta-Galactosidase; Biomarkers; Caloric Restriction; Cellular Senescence; Disease Models, Animal; Hypoglycemic Agents; Kidney; Least-Squares Analysis; Lipid Metabolism; Male; Metabolomics; Multivariate Analysis; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Time Factors

2012
PPAR gamma activation protects the brain against microvascular dysfunction in sepsis.
    Microvascular research, 2012, Volume: 84, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Brain; Cecum; Cerebrovascular Circulation; Cerebrovascular Disorders; Cytoprotection; Disease Models, Animal; Leukocyte Rolling; Ligation; Male; Mice; Microcirculation; Microvessels; Neutrophil Infiltration; PPAR gamma; Punctures; Rosiglitazone; Sepsis; Thiazolidinediones

2012
Design, synthesis and in-vivo hypoglycemic evaluation of novel non - TZD'S in a type - 2 diabetic model.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2013, Volume: 9, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Design; Hypoglycemic Agents; Ligands; Models, Molecular; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones

2013
[Effects of ursolic acid in ameliorating insulin resistance in liver of KKAy mice via peroxisome proliferator-activated receptors α and γ].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2012, Volume: 10, Issue:7

    Topics: Adiponectin; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Hypoglycemic Agents; Insulin Resistance; Liver; Mice; Mice, Inbred C57BL; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid

2012
Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats.
    Human molecular genetics, 2012, Nov-01, Volume: 21, Issue:21

    Topics: Animals; Dendritic Spines; Disease Models, Animal; DNA-Binding Proteins; Entorhinal Cortex; Frontotemporal Lobar Degeneration; Gene Expression Regulation; Golgi Apparatus; Humans; Memory Disorders; Mitochondria; Mutation; PPAR gamma; Prosencephalon; Rats; Rats, Transgenic; RNA-Binding Protein FUS; Rosiglitazone; Thiazolidinediones; Ubiquitin

2012
Rosiglitazone, a PPAR-γ agonist, protects against striatal dopaminergic neurodegeneration induced by 6-OHDA lesions in the substantia nigra of rats.
    Toxicology letters, 2012, Sep-18, Volume: 213, Issue:3

    Topics: Animals; Basal Ganglia; Calcium-Binding Proteins; Cyclooxygenase 2; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Glial Fibrillary Acidic Protein; Injections, Intraperitoneal; Male; Microfilament Proteins; Nerve Degeneration; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Substantia Nigra; Thiazolidinediones; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2012
Uremic cardiomyopathy is characterized by loss of the cardioprotective effects of insulin.
    American journal of physiology. Renal physiology, 2012, Nov-01, Volume: 303, Issue:9

    Topics: Animals; Cardiomyopathies; Cardiotonic Agents; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rosiglitazone; Thiazolidinediones; Uremia

2012
Rosiglitazone prevents graft-versus-host disease (GVHD).
    Transplant immunology, 2012, Volume: 27, Issue:2-3

    Topics: Animals; Antigens, CD; Cells, Cultured; Cytokines; Disease Models, Animal; Gene Expression Regulation; Graft vs Host Disease; Histocompatibility; Humans; Immunophenotyping; Isoantigens; Lymphocyte Culture Test, Mixed; Lymphocyte Subsets; Lymphocytes; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-kappa B; PPAR gamma; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Neurokinin-1; Rosiglitazone; Thiazolidinediones

2012
Sex-specific perinatal nicotine-induced asthma in rat offspring.
    American journal of respiratory cell and molecular biology, 2013, Volume: 48, Issue:1

    Topics: Airway Resistance; Animals; Animals, Newborn; Asthma; Disease Models, Animal; Female; Lung Compliance; Male; Muscle, Smooth; Nicotine; PPAR gamma; Pregnancy; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sex Characteristics; Smoking; Thiazolidinediones; Trachea

2013
Prevention of JNK phosphorylation as a mechanism for rosiglitazone in neuroprotection after transient cerebral ischemia: activation of dual specificity phosphatase.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:1

    Topics: Animals; Blotting, Western; Cell Death; Disease Models, Animal; Dual-Specificity Phosphatases; Enzyme Activation; Glucose; Ischemic Attack, Transient; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Oxygen; Phosphorylation; PPAR gamma; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones

2013
Effects of neferine on CCL5 and CCR5 expression in SCG of type 2 diabetic rats.
    Brain research bulletin, 2013, Volume: 90

    Topics: Analysis of Variance; Animals; Benzylisoquinolines; Blood Glucose; Blood Pressure; Chemokine CCL5; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Female; Gene Expression Regulation; Heart Rate; Hypoglycemic Agents; Insulin; Lipid Metabolism; Lipoproteins, HDL; Male; Neural Conduction; Rats; Rats, Sprague-Dawley; Receptors, CCR5; RNA, Messenger; Rosiglitazone; Superior Cervical Ganglion; Thiazolidinediones

2013
Role of peroxisome proliferator activated receptor-gamma in bacillus Calmette-Guérin bladder cancer therapy.
    The Journal of urology, 2012, Volume: 188, Issue:6

    Topics: Administration, Intravesical; Analysis of Variance; Animals; Blotting, Western; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Gene Expression Regulation; Humans; Immunohistochemistry; Mice; Mice, Inbred Strains; Mycobacterium bovis; Peroxisomes; PPAR gamma; Reference Values; Rosiglitazone; Sensitivity and Specificity; Thiazolidinediones; Tumor Burden; Urinary Bladder Neoplasms

2012
Pkd2 mesenteric vessels exhibit a primary defect in endothelium-dependent vasodilatation restored by rosiglitazone.
    American journal of physiology. Heart and circulatory physiology, 2013, Jan-01, Volume: 304, Issue:1

    Topics: Animals; Antioxidants; Arterioles; Calcium; Capillary Permeability; Cells, Cultured; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Genotype; Heterozygote; Hypertension; Male; Mesentery; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myography; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Phenotype; Polycystic Kidney, Autosomal Dominant; PPAR gamma; Renal Insufficiency; Reperfusion Injury; Rosiglitazone; Superoxides; Thiazolidinediones; Time Factors; TRPP Cation Channels; Vasodilation; Vasodilator Agents; Venules

2013
Plant extracts of winter savory, purple coneflower, buckwheat and black elder activate PPAR-γ in COS-1 cells but do not lower blood glucose in Db/db mice in vivo.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2012, Volume: 67, Issue:4

    Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Chlorocebus aethiops; Cholesterol; COS Cells; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Echinacea; Fagopyrum; Female; Insulin; Mice; Plant Extracts; PPAR gamma; Rosiglitazone; Sambucus nigra; Satureja; Thiazolidinediones; Triglycerides

2012
Reversal of dexamethasone induced insulin resistance in 3T3L1 adipocytes by 3β-taraxerol of Mangifera indica.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Feb-15, Volume: 20, Issue:3-4

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Biomarkers; Dexamethasone; Disease Models, Animal; Drug Evaluation, Preclinical; Glucose; Glucose Transporter Type 4; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Mangifera; Mice; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Phytotherapy; Plant Extracts; Rosiglitazone; Thiazolidinediones

2013
Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease.
    Journal of neurochemistry, 2013, Volume: 125, Issue:3

    Topics: Adenosine Triphosphate; Anilides; Animals; Brain; Brain-Derived Neurotrophic Factor; Cell Line; Disease Models, Animal; Gene Expression Regulation; Glutamates; Humans; Huntingtin Protein; Huntington Disease; Hyperglycemia; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Male; Mice; Mice, Transgenic; Movement Disorders; Nerve Tissue Proteins; Neurons; Neuropeptides; Neuroprotective Agents; Orexins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; RNA, Messenger; Rosiglitazone; Sirtuins; Thiazolidinediones; Trans-Activators; Transcription Factors; Transfection; Trinucleotide Repeat Expansion

2013
Comparison of the anti-inflammatory and therapeutic actions of PPAR-gamma agonists rosiglitazone and troglitazone in experimental colitis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2012, Volume: 63, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Chromans; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Agents; Inflammation Mediators; Interleukin-10; Interleukin-2; Interleukin-4; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Troglitazone

2012
Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Animals; Benzazepines; Binding, Competitive; Blood Glucose; Blood Pressure; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Glucose; Hyperinsulinism; Hypoglycemic Agents; Insulin; Kidney; Kidney Tubules, Proximal; Male; Obesity; Rats; Rats, Zucker; Receptors, Dopamine D1; Rosiglitazone; Sodium-Potassium-Exchanging ATPase; Thiazoles; Thiazolidinediones

2002
Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis.
    Inflammatory bowel diseases, 2002, Volume: 8, Issue:5

    Topics: Acute Disease; Animals; Antibody Formation; Antioxidants; Chromans; Colitis; Cytokines; Disease Models, Animal; Hypoglycemic Agents; Ligands; Mice; Mice, Inbred C57BL; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Th2 Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

2002
Rosiglitazone improves insulin resistance, lipid profile and promotes adiposity in a genetic model of metabolic syndrome X.
    Folia biologica, 2002, Volume: 48, Issue:6

    Topics: Adipose Tissue; Animals; Disease Models, Animal; Glucose; Glucose Tolerance Test; Glycogen; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Rats; Rats, Inbred Strains; Rosiglitazone; Thiazoles; Thiazolidinediones

2002
Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation.
    The Journal of biological chemistry, 2003, Apr-04, Volume: 278, Issue:14

    Topics: Adipocytes; Animals; Blood Vessels; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Diet; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Matrix Metalloproteinases, Membrane-Associated; Matrix Metalloproteinases, Secreted; Metalloendopeptidases; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Obese; Mitosis; Obesity; Phenylalanine; Protease Inhibitors; RNA, Messenger; Rosiglitazone; Stromal Cells; Thiazoles; Thiazolidinediones; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-3

2003
Differential effects of YM440 a hypoglycemic agent on binding to a peroxisome proliferator-activated receptor gamma and its transactivation.
    Biochemical pharmacology, 2003, Mar-01, Volume: 65, Issue:5

    Topics: 3T3 Cells; Adipose Tissue; Animals; Binding Sites; Biological Transport; Carrier Proteins; Diabetes Mellitus; Disease Models, Animal; Fatty Acid-Binding Proteins; Fish Proteins; Glucokinase; Humans; Hypoglycemic Agents; Ion Channels; Liver; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Oxadiazoles; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Trypsin; Tumor Cells, Cultured; Uncoupling Protein 1

2003
Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation.
    The Journal of experimental medicine, 2003, Aug-04, Volume: 198, Issue:3

    Topics: Anilides; Animals; Asthma; Chemotaxis; Disease Models, Animal; DNA-Binding Proteins; Down-Regulation; Eosinophils; GATA3 Transcription Factor; Humans; Inflammation; Lung; Mice; Mice, Inbred BALB C; Mice, Knockout; Rats; Receptors, Cytoplasmic and Nuclear; Respiratory Hypersensitivity; Rosiglitazone; Thiazoles; Thiazolidinediones; Trans-Activators; Transcription Factors

2003
Rosiglitazone reduces the accelerated neointima formation after arterial injury in a mouse injury model of type 2 diabetes.
    Circulation, 2003, Oct-21, Volume: 108, Issue:16

    Topics: Animals; Blood Glucose; Carotid Arteries; Carotid Artery Injuries; Cells, Cultured; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Female; Homozygote; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Islets of Langerhans; Lipids; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Rosiglitazone; Thiazoles; Thiazolidinediones; Tunica Intima

2003
PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:2

    Topics: Acetylcholine; Adenosine; Animals; Arterioles; Biological Availability; Coronary Vessels; Diabetes Mellitus, Type 2; Disease Models, Animal; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Vasodilation

2004
Effect of thalidomide and rosiglitazone on the prevention of diabetic retinopathy in streptozotocin-induced diabetic rats.
    Diabetologia, 2003, Volume: 46, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Aqueous Humor; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Hypoglycemic Agents; Rats; Rats, Sprague-Dawley; Retinal Vessels; Rosiglitazone; Thalidomide; Thiazolidinediones; Vascular Endothelial Growth Factor A

2003
Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia.
    Circulation, 2003, Dec-02, Volume: 108, Issue:22

    Topics: Animals; Antioxidants; Blood Vessels; Carotid Arteries; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Hypercholesterolemia; In Vitro Techniques; Lipids; Male; Nitrates; Nitric Oxide; Nitrites; Rabbits; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Tyrosine; Vasodilation

2003
Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease.
    Annals of surgery, 2004, Volume: 239, Issue:1

    Topics: Anastomosis, Surgical; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Duodenum; Eating; Follow-Up Studies; Gastric Bypass; Glucose Tolerance Test; Jejunum; Male; Obesity; Probability; Random Allocation; Rats; Rats, Inbred Strains; Reference Values; Rosiglitazone; Thiazolidinediones; Weight Loss

2004
Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma.
    The American journal of pathology, 2004, Volume: 164, Issue:1

    Topics: Anilides; Animals; Asthma; Cell Movement; Cytokines; Dendritic Cells; Disease Models, Animal; Eosinophils; Inflammation; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; T-Lymphocytes; Thiazolidinediones; Transcription Factors; Vasodilator Agents

2004
Differential effects of peroxisome proliferator activator receptor-alpha and gamma ligands on intimal hyperplasia after balloon catheter-induced vascular injury in Zucker rats.
    Journal of cardiovascular pharmacology and therapeutics, 2003, Volume: 8, Issue:4

    Topics: Animals; Biomarkers; Blood Glucose; Body Weight; Catheterization; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Fenofibrate; Hyperplasia; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Ligands; Models, Cardiovascular; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Triglycerides; Tunica Intima

2003
Lysophosphatidic acid induces neointima formation through PPARgamma activation.
    The Journal of experimental medicine, 2004, Mar-15, Volume: 199, Issue:6

    Topics: Analysis of Variance; Anilides; Animals; Arteriosclerosis; Calmodulin-Binding Proteins; Carotid Artery Diseases; CD36 Antigens; Cells, Cultured; Disease Models, Animal; DNA Primers; Growth Substances; Ligands; Lipoproteins, LDL; Lysophospholipids; Male; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Structure-Activity Relationship; Thiazolidinediones; Time Factors; Transcription Factors

2004
Increased adipose tissue expression of Grb14 in several models of insulin resistance.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:9

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adipocytes; Adipose Tissue; Animals; Carrier Proteins; Diabetes Mellitus, Type 2; Disease Models, Animal; Fasting; Gene Expression Regulation; Insulin; Insulin Resistance; Liver; Metformin; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscles; Obesity; Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones

2004
Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster, an animal model of nutritionally-induced insulin resistance.
    Atherosclerosis, 2004, Volume: 174, Issue:2

    Topics: Analysis of Variance; Animals; Blood Glucose; Cricetinae; Dietary Fats; Disease Models, Animal; Glucose Clamp Technique; Hypoglycemic Agents; Insulin Resistance; Intestinal Absorption; Intestinal Mucosa; Lipoproteins; Male; Mesocricetus; Probability; Random Allocation; Rosiglitazone; Sensitivity and Specificity; Thiazolidinediones

2004
PPAR-gamma agonists as therapy for diseases involving airway neutrophilia.
    The European respiratory journal, 2004, Volume: 24, Issue:1

    Topics: Administration, Oral; Airway Resistance; Analysis of Variance; Animals; Bronchial Hyperreactivity; Disease Models, Animal; Inflammation Mediators; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Neutrophils; Peroxisome Proliferator-Activated Receptors; Probability; Reference Values; Rosiglitazone; Sensitivity and Specificity; Thiazolidinediones

2004
Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease.
    Neurobiology of disease, 2004, Volume: 17, Issue:3

    Topics: Alzheimer Disease; Animals; Blood Glucose; Disease Models, Animal; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Reference Values; Rosiglitazone; Stress, Physiological; Thiazolidinediones

2004
Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes.
    Diabetologia, 2004, Volume: 47, Issue:12

    Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Transgenic; PPAR gamma; Rosiglitazone; Thiazolidinediones

2004
The peroxisome proliferator-activated receptor gamma ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency.
    Inflammatory bowel diseases, 2005, Volume: 11, Issue:3

    Topics: Animals; Cytokines; Disease Models, Animal; Disease Progression; Female; Gene Expression Regulation; Hyperplasia; Hypoglycemic Agents; Inflammatory Bowel Diseases; Interleukin-10; Male; Mice; PPAR gamma; Rosiglitazone; Thiazolidinediones

2005
PPAR-gamma modulates allergic inflammation through up-regulation of PTEN.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:8

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Female; Gene Expression; Gene Expression Regulation; Interleukin-13; Interleukin-4; Interleukin-5; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Phosphatidylinositol 3-Kinases; Phosphorylation; Pioglitazone; PPAR gamma; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Trachea; Transfection

2005
Agonist of peroxisome proliferator-activated receptor-gamma, rosiglitazone, reduces renal injury and dysfunction in a murine sepsis model.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Disease Models, Animal; Epithelial Cells; I-kappa B Proteins; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin-1; Kidney Tubules; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; NF-kappa B; NF-KappaB Inhibitor alpha; Rosiglitazone; Sepsis; Thiazolidinediones; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2005
Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes.
    Diabetes, 2005, Volume: 54, Issue:6

    Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Hypoglycemic Agents; Liver; Male; Mice; Mice, Congenic; Pharmacogenetics; Phenotype; Phosphatidylcholines; Rosiglitazone; Thiazolidinediones

2005
PPARalpha, but not PPARgamma, activators decrease macrophage-laden atherosclerotic lesions in a nondiabetic mouse model of mixed dyslipidemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:9

    Topics: Animals; Apolipoprotein E2; Apolipoproteins E; Atherosclerosis; Blood Glucose; Disease Models, Animal; Dyslipidemias; Female; Fenofibrate; Foam Cells; Homeostasis; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Macrophages; Mice; Mice, Mutant Strains; Pioglitazone; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones

2005
Rosiglitazone attenuates atherosclerosis in a model of insulin insufficiency independent of its metabolic effects.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:9

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Oxidative Stress; Rosiglitazone; Thiazolidinediones; Triglycerides; Vasculitis

2005
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Disease Models, Animal; Drug Administration Schedule; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; NF-kappa B; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Oligonucleotide Array Sequence Analysis; PPAR gamma; Prostaglandin D2; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Time Factors

2006
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes.
    Nature, 2005, Jul-21, Volume: 436, Issue:7049

    Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation; Glucose Transporter Type 4; Hepatocytes; Insulin; Insulin Resistance; Liver; Mice; Mice, Knockout; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Obesity; Oligonucleotide Array Sequence Analysis; Phosphoenolpyruvate Carboxykinase (GTP); Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Rosiglitazone; Signal Transduction; Thiazolidinediones

2005
Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's disease is not improved by treatment with hypoglycaemic agents.
    Experimental brain research, 2005, Volume: 166, Issue:2

    Topics: Administration, Oral; Animals; Behavior, Animal; Diabetes Mellitus; Disease Models, Animal; Exocytosis; Glucose Intolerance; Glyburide; Glycosuria; Huntington Disease; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Neurologic Mutants; Mice, Transgenic; Rosiglitazone; Thiazolidinediones

2005
Involvement of IL-10 in peroxisome proliferator-activated receptor gamma-mediated anti-inflammatory response in asthma.
    Molecular pharmacology, 2005, Volume: 68, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Immunoglobulin E; Inflammation; Interleukin-10; Interleukins; Lung; Mice; Pioglitazone; PPAR gamma; Rosiglitazone; Thiazolidinediones

2005
Differential endocrine responses to rosiglitazone therapy in new mouse models of type 2 diabetes.
    Endocrinology, 2006, Volume: 147, Issue:2

    Topics: Adiponectin; Analysis of Variance; Animals; Biomarkers; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Glucose Intolerance; Hypoglycemic Agents; Insulin; Leptin; Male; Mice; Mice, Congenic; Mice, Inbred NOD; Mice, Obese; Obesity; Phenotype; Plasminogen Activator Inhibitor 1; Quantitative Trait, Heritable; Recombination, Genetic; Resistin; Rosiglitazone; Species Specificity; Syndrome; Thiazolidinediones

2006
The PPARgamma ligand, rosiglitazone, reduces airways hyperresponsiveness in a murine model of allergen-induced inflammation.
    Pulmonary pharmacology & therapeutics, 2006, Volume: 19, Issue:1

    Topics: Allergens; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Goblet Cells; Guinea Pigs; Hyperplasia; In Vitro Techniques; Injections, Intraperitoneal; Ligands; Matrix Metalloproteinase 2; Methacholine Chloride; Mice; Mice, Inbred C57BL; Muscle Contraction; Ovalbumin; Pneumonia; PPAR gamma; Respiratory Hypersensitivity; Rosiglitazone; Thiazolidinediones; Time Factors; Trachea; Vasodilator Agents

2006
(+)-Z-Bisdehydrodoisynolic acid ameliorates obesity and the metabolic syndrome in female ZDF rats.
    Obesity research, 2005, Volume: 13, Issue:11

    Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Coronary Vessels; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Gene Expression; Hypoglycemic Agents; Kidney; Liver; Metabolic Syndrome; Obesity; Organ Size; Phenanthrenes; PPAR alpha; PPAR gamma; Random Allocation; Rats; Rats, Zucker; Risk Factors; Rosiglitazone; Selective Estrogen Receptor Modulators; Thiazolidinediones; Triglycerides

2005
Effect of peroxisome proliferator-activated receptor-gamma agonist rosiglitazone on the induction of endometriosis in an experimental rat model.
    Journal of the Society for Gynecologic Investigation, 2006, Volume: 13, Issue:1

    Topics: Animals; Disease Models, Animal; Endometriosis; Endometrium; Female; Hypoglycemic Agents; Inflammation; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2006
Effects of glitazones on blood pressure and vascular structure in mesenteric resistance arteries and basilar artery from genetically hypertensive rats.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:11

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Basilar Artery; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Mesenteric Arteries; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Wistar; Rosiglitazone; Simvastatin; Tetrazoles; Thiazolidinediones; Tunica Media; Valine; Valsartan

2005
Apoptosis and proliferation of cultured mesangial cells isolated from kidneys of rosiglitazone-treated pregnant diabetic rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:5

    Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Diabetes Mellitus; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Glomerular Mesangium; In Situ Nick-End Labeling; PPAR gamma; Pregnancy; Pregnancy, Animal; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Risk Factors; Rosiglitazone; Sensitivity and Specificity; Statistics, Nonparametric; Streptozocin; Thiazolidinediones; Transforming Growth Factor beta

2006
Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice.
    Experimental neurology, 2006, Volume: 199, Issue:2

    Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibrinolytic Agents; In Situ Hybridization; Insulysin; Learning Disabilities; Male; Memory Disorders; Metyrapone; Mice; Mice, Transgenic; Rosiglitazone; Thiazolidinediones

2006
Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.
    Journal of neurochemistry, 2006, Volume: 97, Issue:2

    Topics: Anilides; Animals; Animals, Newborn; Behavior, Animal; Blood Pressure; Body Temperature; Brain Ischemia; Cells, Cultured; Cerebral Infarction; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression; Gene Expression Regulation; Granulocyte Colony-Stimulating Factor; Immunohistochemistry; Infarction, Middle Cerebral Artery; Intercellular Adhesion Molecule-1; Interleukin-3; Lectins; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Peroxidase; PPAR gamma; Psychomotor Performance; Recombinant Fusion Proteins; Recombinant Proteins; Reperfusion; Rosiglitazone; Thiazolidinediones

2006
Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo.
    Biochemical pharmacology, 2006, Jun-28, Volume: 72, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Anilides; Animals; Binding, Competitive; Body Weight; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Glucose Tolerance Test; Hepatocytes; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones

2006
PPAR-alpha and -gamma agonists attenuate diabetic kidney disease in the apolipoprotein E knockout mouse.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:9

    Topics: Animals; Apolipoproteins E; Collagen Type IV; Creatinine; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Gemfibrozil; Hypoglycemic Agents; Hypolipidemic Agents; Male; Mice; Mice, Knockout; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones

2006
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism.
    Vascular pharmacology, 2006, Volume: 45, Issue:1

    Topics: Animals; Cardiolipins; Cardiovascular System; Choline-Phosphate Cytidylyltransferase; Crosses, Genetic; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred NOD; Mice, Obese; Mitochondria, Heart; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; PPAR gamma; Rosiglitazone; Thiazolidinediones

2006
The PPARalpha/gamma dual agonist chiglitazar improves insulin resistance and dyslipidemia in MSG obese rats.
    British journal of pharmacology, 2006, Volume: 148, Issue:5

    Topics: Adipose Tissue; Animals; Blood Glucose; Carbazoles; Disease Models, Animal; Dyslipidemias; Gene Expression; Gluconeogenesis; Hypoglycemic Agents; Insulin Resistance; Lipids; Liver; Liver Glycogen; Muscles; Obesity; Pancreas; Pioglitazone; PPAR alpha; PPAR gamma; Propionates; Pyrimidines; Rats; Rats, Wistar; Rosiglitazone; Sodium Glutamate; Thiazolidinediones

2006
[Therapeutic effects of insulin-sensitizing drugs on nonalcoholic fatty liver disease: experiment with rats].
    Zhonghua yi xue za zhi, 2006, May-16, Volume: 86, Issue:18

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholesterol; Dietary Fats; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; fas Receptor; Fatty Liver; Gene Expression; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Triglycerides; Tumor Necrosis Factor-alpha

2006
The effect of rosiglitazone in the prevention of intra-abdominal adhesion formation in a rat uterine horn model.
    Human reproduction (Oxford, England), 2006, Volume: 21, Issue:11

    Topics: Animals; Disease Models, Animal; Female; Hypoglycemic Agents; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Tissue Adhesions; Uterine Diseases; Uterus

2006
Peroxisome proliferator activated receptor gamma activity is low in mature primary human visceral adipocytes.
    Diabetologia, 2007, Volume: 50, Issue:1

    Topics: Adipocytes; Adult; Aged; Aged, 80 and over; Animals; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Intra-Abdominal Fat; Luciferases, Firefly; Male; Mice; Mice, Inbred Strains; Middle Aged; Obesity; PPAR gamma; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones; Transfection

2007
[Stress and inflammatory bowell disease (I.B.D). Therapeutic strategies].
    Anales de la Real Academia Nacional de Medicina, 2006, Volume: 123, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Translocation; Colitis, Ulcerative; Disease Models, Animal; Humans; Immobilization; Immunoglobulin A; Inflammatory Bowel Diseases; PPAR gamma; Prostaglandin D2; Prostaglandins; Rats; Rosiglitazone; Stress, Psychological; Thiazolidinediones; Time Factors

2006
Effect of PPAR-gamma agonist on adiponectin levels in the metabolic syndrome: lessons from the high fructose fed rat model.
    American journal of hypertension, 2007, Volume: 20, Issue:2

    Topics: Adiponectin; Adipose Tissue; Animals; Blood Pressure; Diet; Disease Models, Animal; Fructose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Male; Metabolic Syndrome; PPAR gamma; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Triglycerides; Up-Regulation

2007
Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:6

    Topics: Adipocytes; Adiponectin; Adipose Tissue; Adiposity; Animals; Apoptosis; Body Weight; Dietary Fats; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Hypoglycemic Agents; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Leptin; Linoleic Acids, Conjugated; Lipid Metabolism; Lipoproteins, VLDL; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors; Triglycerides

2007
Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation.
    Circulation, 2007, Mar-13, Volume: 115, Issue:10

    Topics: Adiponectin; Animals; Apolipoproteins E; Becaplermin; Cell Proliferation; Cells, Cultured; Diet; Disease Models, Animal; Female; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; PPAR gamma; Proto-Oncogene Proteins c-sis; Risk Factors; Rosiglitazone; Sex Factors; Thiazolidinediones

2007
PPAR gamma agonists partially restores hyperglycemia induced aggravation of vascular dysfunction to angiotensin II in thoracic aorta isolated from rats with insulin resistance.
    Pharmacological research, 2007, Volume: 55, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Male; Pioglitazone; PPAR gamma; Prediabetic State; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Rosiglitazone; Streptozocin; Thiazolidinediones; Vasoconstriction; Vasoconstrictor Agents

2007
Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents.
    Journal of neurochemistry, 2007, Volume: 101, Issue:1

    Topics: Anilides; Animals; Cerebral Infarction; Chemotaxis, Leukocyte; Cytokines; Diabetes Mellitus, Type 2; Disease Models, Animal; Encephalitis; Hypertension; Intercellular Adhesion Molecule-1; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neuroprotective Agents; Pioglitazone; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rosiglitazone; Superoxide Dismutase; Superoxide Dismutase-1; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Thiazolidinediones

2007
Hypoglycemic action of thiazolidinediones/peroxisome proliferator-activated receptor gamma by inhibition of the c-Jun NH2-terminal kinase pathway.
    Diabetes, 2007, Volume: 56, Issue:7

    Topics: Adipocytes; Adipose Tissue; Animals; Cells, Cultured; Chromans; Diabetes Mellitus, Type 2; Disease Models, Animal; Hypoglycemic Agents; Insulin-Secreting Cells; JNK Mitogen-Activated Protein Kinases; Liver; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones; Troglitazone

2007
Comparison of mitochondrial and macrophage content between subcutaneous and visceral fat in db/db mice.
    Experimental and molecular pathology, 2007, Volume: 83, Issue:1

    Topics: Adipocytes; Animals; Blood Glucose; Body Weight; Cell Count; Cell Shape; Cell Size; Chaperonin 60; Diabetes Mellitus; Disease Models, Animal; Intra-Abdominal Fat; Ion Channels; Macrophages; Male; Mice; Mitochondria; Mitochondrial Proteins; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones; Uncoupling Protein 1

2007
Rosiglitazone attenuates liver inflammation in a rat model of nonalcoholic steatohepatitis.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:12

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Disease Models, Animal; Disease Progression; Fatty Liver; Hypoglycemic Agents; Immunoenzyme Techniques; Insulin; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Luminescent Measurements; Male; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Tumor Necrosis Factor-alpha

2007
Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance.
    Diabetes, 2007, Volume: 56, Issue:7

    Topics: Animals; Dietary Fats; Disease Models, Animal; Exercise Therapy; Glucose; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones

2007
Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone.
    Diabetes, 2007, Volume: 56, Issue:7

    Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Transcription, Genetic

2007
Beneficial effects of thiazolidinediones on diabetic nephropathy in OLETF rats.
    Yonsei medical journal, 2007, Apr-30, Volume: 48, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Hypoglycemic Agents; Male; Pioglitazone; Rats; Rats, Long-Evans; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factor A

2007
Induction of PPAR gamma mRNA and protein expression by rosiglitazone in chronic cyclosporine nephropathy in the rat.
    Yonsei medical journal, 2007, Apr-30, Volume: 48, Issue:2

    Topics: Animals; Cyclosporine; Disease Models, Animal; Gene Expression Regulation; Kidney Diseases; Male; PPAR gamma; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription, Genetic

2007
The PPARgamma agonist rosiglitazone impairs colonic inflammation in mice with experimental colitis.
    Journal of clinical immunology, 2007, Volume: 27, Issue:3

    Topics: Animals; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Membrane Proteins; Mice; Mice, Inbred C57BL; Peroxidase; Phosphoproteins; PPAR gamma; Rosiglitazone; Serum Amyloid P-Component; Spleen; Thiazolidinediones; Zonula Occludens-1 Protein

2007
Ameliorative effect of combination of fenofibrate and rosiglitazone in pressure overload-induced cardiac hypertrophy in rats.
    Pharmacology, 2007, Volume: 80, Issue:2-3

    Topics: Analysis of Variance; Animals; Aorta, Abdominal; Blood Pressure; Cardiomegaly; Collagen; Constriction, Pathologic; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fenofibrate; Hypoglycemic Agents; Male; Myocardium; Myocytes, Cardiac; Organ Size; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Ventricular Function, Left

2007
Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone reduces the size of experimental endometriosis in the rat model.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2007, Volume: 47, Issue:4

    Topics: Animals; Disease Models, Animal; Endometriosis; Endometrium; Female; Macrophages; PPAR gamma; Rats; Rats, Wistar; Remission Induction; Rosiglitazone; Thiazolidinediones

2007
Thiazolidinediones inhibit the progression of established hypertension in the Dahl salt-sensitive rat.
    Diabetes & vascular disease research, 2007, Volume: 4, Issue:2

    Topics: Adiponectin; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Disease Models, Animal; Disease Progression; Heart Rate; Hypertension; Insulin; Lipids; Male; PPAR gamma; Pyridines; Rats; Rats, Inbred Dahl; Rosiglitazone; Sodium Chloride, Dietary; Thiazolidinediones

2007
The peroxisome proliferator activated receptor gamma (PPARgamma) ligand rosiglitazone modulates bronchoalveolar lavage levels of leptin, adiponectin, and inflammatory cytokines in lean and obese mice.
    Lung, 2007, Volume: 185, Issue:6

    Topics: Adiponectin; Animals; Biomarkers; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hypoglycemic Agents; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Treatment Outcome

2007
Effects of rosiglitazone on methionine-choline deficient diet-induced nonalcoholic steatohepatitis.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Choline; Diet; Disease Models, Animal; Fatty Liver; Liver; Methionine; Mice; Mitochondria, Liver; Rosiglitazone; Thiazolidinediones

2007
Amelioration of anti-Thy1-glomerulonephritis by PPAR-gamma agonism without increase of endothelial progenitor cell homing.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:2

    Topics: Aneurysm; Animals; Blood Pressure; Bone Marrow Transplantation; Cell Movement; Disease Models, Animal; Endothelial Cells; Extracellular Matrix; Fibronectins; Gene Expression; Glomerulonephritis, Membranous; Hypoglycemic Agents; Isoantibodies; Kidney Cortex; Kidney Glomerulus; Male; Membrane Proteins; Plasminogen Activator Inhibitor 1; PPAR gamma; Proteinuria; Rats; Rats, Inbred BN; Rosiglitazone; Stem Cells; Thiazolidinediones; Transforming Growth Factor beta; Urea

2008
Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules.
    Atherosclerosis, 2008, Volume: 199, Issue:1

    Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Cell Adhesion Molecules; Cells, Cultured; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Disease Models, Animal; Down-Regulation; Endothelial Cells; Humans; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Umbilical Veins; Vascular Cell Adhesion Molecule-1; Vasculitis

2008
PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fatty-acid metabolic enzymes.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:1

    Topics: Animals; Disease Models, Animal; Fatty Acids; Fatty Liver; Fenofibrate; Gene Expression Profiling; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; PPAR alpha; PPAR gamma; Rats; Rosiglitazone; Thiazolidinediones

2008
Thiazolidinedione drugs block cardiac KATP channels and may increase propensity for ischaemic ventricular fibrillation in pigs.
    Diabetologia, 2008, Volume: 51, Issue:4

    Topics: Animals; Blood Pressure; Disease Models, Animal; Heart; KATP Channels; Pioglitazone; Rosiglitazone; Swine; Thiazolidinediones; Ventricular Fibrillation

2008
Activation of cerebral peroxisome proliferator-activated receptors gamma exerts neuroprotection by inhibiting oxidative stress following pilocarpine-induced status epilepticus.
    Brain research, 2008, Mar-20, Volume: 1200

    Topics: Animals; Benzamides; Cell Death; Convulsants; Disease Models, Animal; Glutathione; Heme Oxygenase (Decyclizing); Hippocampus; Lipid Peroxidation; Lithium; Male; Muscarinic Agonists; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Pilocarpine; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rosiglitazone; Status Epilepticus; Superoxide Dismutase; Superoxide Dismutase-1; Thiazolidinediones

2008
Insulin resistance and impaired functional vasodilation in obese Zucker rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Animals; Antioxidants; Arachidonic Acid; Arterioles; Blood Glucose; Bridged Bicyclo Compounds, Heterocyclic; Cyclic N-Oxides; Disease Models, Animal; Electric Stimulation; Fatty Acids, Unsaturated; Hydrazines; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Insulin; Insulin Resistance; Kidney Cortex; Male; Muscle, Skeletal; NADPH Oxidases; Obesity; Oxidative Stress; Rats; Rats, Zucker; Receptors, Thromboxane; Rosiglitazone; Spin Labels; Superoxides; Thiazolidinediones; Thromboxanes; Time Factors; Triglycerides; Vasoconstriction; Vasodilation

2008
Reduced cardiotropic response to insulin in spontaneously hypertensive rats: role of peroxisome proliferator-activated receptor-gamma-initiated signaling.
    Journal of hypertension, 2008, Volume: 26, Issue:3

    Topics: Animals; Disease Models, Animal; Gene Expression; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Myocardial Contraction; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; PPAR gamma; Rats; Rats, Inbred WKY; Rosiglitazone; Signal Transduction; Thiazolidinediones; Vasodilator Agents

2008
A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.
    European journal of pharmacology, 2008, Apr-14, Volume: 584, Issue:1

    Topics: 3T3-L1 Cells; Acetates; Adipose Tissue, White; Animals; Cardiomegaly; Cardiovascular Diseases; Chlorocebus aethiops; COS Cells; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Partial Agonism; Gene Expression Profiling; Gene Expression Regulation; Hemodilution; Humans; Hypoglycemic Agents; Indoles; Insulin Resistance; Male; Mice; Mice, Inbred Strains; PPAR alpha; PPAR delta; PPAR gamma; Propionates; Protein Binding; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones; Transcriptional Activation; Transfection; Water-Electrolyte Balance

2008
The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice.
    Life sciences, 2008, May-07, Volume: 82, Issue:19-20

    Topics: Animals; Dietary Fats; Disease Models, Animal; Fatty Acids; Fatty Liver; Fenofibrate; Gene Expression; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones

2008
[Study on renoprotective effect of Xuebijing and Rosiglitazone in rats with focal segmental glomerular fibrosis].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2008, Volume: 20, Issue:5

    Topics: Animals; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Kidney Glomerulus; Male; Random Allocation; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2008
Rosiglitazone prevents murine hepatic fibrosis induced by Schistosoma japonicum.
    World journal of gastroenterology, 2008, May-14, Volume: 14, Issue:18

    Topics: Actins; Animals; Anthelmintics; Collagen Type I; Collagen Type III; Disease Models, Animal; Hypoglycemic Agents; Interleukin-6; Liver; Liver Cirrhosis; Mice; NF-kappa B; PPAR gamma; Praziquantel; RNA, Messenger; Rosiglitazone; Schistosoma japonicum; Schistosomiasis japonica; Thiazolidinediones; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2008
Rosiglitazone, a PPAR gamma agonist, attenuates inflammation after surgical brain injury in rodents.
    Brain research, 2008, Jun-18, Volume: 1215

    Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Disease Models, Animal; Drug Administration Schedule; Inflammation; Intraoperative Complications; Male; Neuroprotective Agents; Neurosurgical Procedures; Peroxidase; Postoperative Complications; PPAR gamma; Random Allocation; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Treatment Outcome

2008
Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes. Association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling.
    Diabetes, 1995, Volume: 44, Issue:9

    Topics: Adipocytes; Adipose Tissue; Affinity Labels; Animals; Azides; Blood Glucose; Cell Membrane; Cholesterol; Diabetes Mellitus, Type 2; Diet; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Epididymis; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance Test; Glucose Transporter Type 4; Glycosides; Hypoglycemic Agents; Insulin; Kinetics; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Monosaccharide Transport Proteins; Muscle Proteins; Propylamines; Rosiglitazone; Thiazoles; Thiazolidinediones; Triglycerides

1995
Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution.
    British journal of pharmacology, 1999, Volume: 128, Issue:7

    Topics: Animals; Body Weight; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Hemodilution; Hemodynamics; Hypoglycemic Agents; Insulin; Leptin; Male; Obesity; Rats; Rats, Wistar; Rosiglitazone; Thiazoles; Thiazolidinediones

1999
Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones.
    The Journal of clinical investigation, 2000, Volume: 106, Issue:10

    Topics: Adipose Tissue; Animals; Blood Glucose; Chromans; Diabetes Mellitus, Lipoatrophic; Disease Models, Animal; Female; Hypoglycemic Agents; Insulin; Ligands; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Cytoplasmic and Nuclear; Respiratory Function Tests; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides; Troglitazone

2000
Expression and function of peroxisome proliferator-activated receptor-gamma in mesangial cells.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Animals; Cell Nucleus; Cells, Cultured; Chromans; Cytoplasm; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Fibrinolysin; Glomerular Mesangium; Matrix Metalloproteinase Inhibitors; Plasminogen Activator Inhibitor 1; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

2001
Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.
    Molecular pharmacology, 2001, Volume: 59, Issue:4

    Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression; Glucose Tolerance Test; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Liver; Male; Muscle, Skeletal; Nicotinic Acids; Obesity; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors

2001
PPARgamma and inflammatory bowel disease: a new therapeutic target for ulcerative colitis and Crohn's disease.
    Trends in molecular medicine, 2001, Volume: 7, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Chromans; Colitis, Ulcerative; Crohn Disease; Disease Models, Animal; Inflammation; Intestines; Ligands; Mice; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

2001
Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo.
    Circulation, 2002, Mar-12, Volume: 105, Issue:10

    Topics: Actins; Angiotensin II; Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Cell Size; Cells, Cultured; Chromans; Disease Models, Animal; Gene Expression; Heart; Heterozygote; Hypoglycemic Agents; Ligands; Mice; Mice, Knockout; Myocardium; Organ Size; Pioglitazone; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

2002
Normalization of skeletal muscle glycogen synthesis and glycolysis in rosiglitazone-treated Zucker fatty rats: an in vivo nuclear magnetic resonance study.
    Diabetes, 2002, Volume: 51, Issue:7

    Topics: Animals; Disease Models, Animal; Gluconeogenesis; Glycolysis; Kinetics; Magnetic Resonance Spectroscopy; Models, Biological; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Reference Values; Rosiglitazone; Thiazoles; Thiazolidinediones

2002