Page last updated: 2024-08-25

rosiglitazone and Aging

rosiglitazone has been researched along with Aging in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.33)18.2507
2000's10 (41.67)29.6817
2010's9 (37.50)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Cao, D; Guo, J; Mo, C; Qin, J; Shen, L; Sun, Y; Wei, H; Xiong, Y; Yue, R; Zhang, X; Zhang, Y; Zhao, C1
Appay, V; Boddaert, J; Cabral-Piccin, MP; Caputo, A; Clave, E; Dubois, M; Dupré, L; Folcher, V; Frere, JJ; Fusaro, M; Gallerani, E; Gavioli, R; Gostick, E; Llewellyn-Lacey, S; Nicoli, F; Papagno, L; Price, DA; Toubert, A; Vallet, H1
Calzone, R; Cugno, C; Halade, GV; Kizhakayil, D; Rahman, MM; Rahman, SM1
Chen, L; Cheng, Q; Evans-Molina, C; Lam, KS; Leung, PS; So, WY; Xu, A1
Bi, B; Chen, L; Guo, Y; Liu, T; Yang, P; Yang, Q; Zeng, J; Zhou, Y; Zhu, J; Zhu, N1
Bing, X; Fei, L; Jun, L; Qian-qian, S; Shuang, W; Yong-Jun, H; Zhang-Min, M1
Amin, R; Dixit, VD; Leff, T; Smith, SR; Yang, H; Youm, YH1
Blau, C; Cowley, TR; Deighan, BF; Jones, R; Kerskens, C; Lynch, MA; O'Sullivan, J; Richardson, JC; Upton, N; Virley, D1
Baxter, JD; Collins, AR; Finegold, MJ; Gupte, AA; Hsueh, WA; Liu, JZ; Lyon, CJ; Minze, LJ; Moore, DD; Pratico, D; Ren, Y; Webb, P; Wiles, JR; Wong, ST1
Fernandes, G; Halade, GV; Lindsey, ML; Williams, PJ1
Czernik, PJ; Huang, S; Krings, A; Lecka-Czernik, B; Lu, Y; Rahman, S1
Barlow, S; Bechara, R; Callaghan, C; Della-Chiesa, A; Hok, V; Irving, E; O'Mara, SM; Tsanov, M; Upton, N; Virley, DJ; Wang, BW1
Bickford, PC; Browning, MD; Coultrap, SJ; Fister, M; Gemma, C; Mesches, MH; Stellwagen, H1
Ali, AA; Jilka, RL; Manolagas, SC; Parfitt, AM; Stewart, SA; Weinstein, RS1
Ecelbarger, CA; Hu, X; Khan, O; Riazi, S; Song, J; Wade, JB1
Alegret, M; Laguna, JC; Roglans, N; Sánchez, RM; Sanguino, E; Vázquez-Carrera, M1
Hogue, WR; Lazarenko, OP; Lecka-Czernik, B; Rzonca, SO; Suva, LJ; Swain, FL1
Fu, WM; Lin, CP; Lin, TH; Tang, CH; Yang, RS1
Goldberg, IJ; Homma, S; Huang, LS; Huggins, LA; Okajima, K; Park, TS; Son, NH; Szabolcs, MJ; Yamashita, H; Yokoyama, M1
Clarke, RM; Deighan, BF; Griffin, RJ; Loane, DJ; Lynch, AM; Lynch, MA1
Connor, SC; Hughes, MG; Lister, CA; Moore, G; Smith, SA1
Andersson, Y; Fruchart, JC; Kosykh, V; Lefebvre, AM; Majd, Z; Martin, G; Najib, J; Sechkin, AV; Staels, B1
Buckingham, RE; Lister, CA; Smith, SA; Toseland, CD1
Buckingham, RE; Finegood, DT; Kojwang, D; Leonard, T; McArthur, MD; Thomas, MJ; Topp, BG1

Other Studies

24 other study(ies) available for rosiglitazone and Aging

ArticleYear
Single-cell transcriptomics of LepR-positive skeletal cells reveals heterogeneous stress-dependent stem and progenitor pools.
    The EMBO journal, 2022, 02-15, Volume: 41, Issue:4

    Topics: Aging; Animals; Antigens, Ly; Bone and Bones; Cell Differentiation; Cell Lineage; Colony-Forming Units Assay; Female; Fractures, Bone; Gene Expression Profiling; Homeodomain Proteins; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Leptin; Rosiglitazone; Single-Cell Analysis; Stem Cells; Stress, Physiological

2022
Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8
    Journal of immunology (Baltimore, Md. : 1950), 2022, 02-01, Volume: 208, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Apoptosis; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Division; COVID-19; Female; Fenofibrate; Glucose; HLA-A2 Antigen; Humans; Hypolipidemic Agents; Immunocompetence; Influenza, Human; Lipid Metabolism; Lymphocyte Activation; Male; MART-1 Antigen; Middle Aged; Neoplasms; Peptide Fragments; Rosiglitazone; Single-Blind Method; Vaccination; Viral Vaccines; Young Adult

2022
Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging C57BL/6 mice and in vitro studies.
    Scientific reports, 2021, 05-14, Volume: 11, Issue:1

    Topics: Adipogenesis; Aging; Animals; Bone Diseases, Metabolic; Cell Differentiation; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Fatty Acids, Omega-3; Female; Humans; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Primary Cell Culture; RAW 264.7 Cells; Rosiglitazone

2021
High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling.
    Diabetes, 2013, Volume: 62, Issue:11

    Topics: Aging; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fibroblast Growth Factors; Glucose; Islets of Langerhans; Klotho Proteins; Male; Membrane Proteins; Mice; Phosphorylation; PPAR gamma; Rosiglitazone; Signal Transduction; Thiazolidinediones

2013
Rosiglitazone ameliorates senescence-like phenotypes in a cellular photoaging model.
    Journal of dermatological science, 2015, Volume: 77, Issue:3

    Topics: Aging; Animals; beta-Galactosidase; Catalase; Cell Cycle Checkpoints; Cell Survival; Cells, Cultured; Collagen Type I; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; Hypoglycemic Agents; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Models, Biological; Phenotype; PPAR gamma; Reactive Oxygen Species; Rosiglitazone; Skin Aging; Thiazolidinediones; Tumor Suppressor Protein p53; Ultraviolet Rays

2015
Rosiglitazone Attenuates Memory Impairment in Aged Rat with Diabetes by Inhibiting NF-kappa B Signal Pathway Activation.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2015, Volume: 123, Issue:9

    Topics: Aging; Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Memory Disorders; NF-kappa B; Rats; Rats, Wistar; Rosiglitazone; Signal Transduction; Thiazolidinediones

2015
Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution.
    Aging cell, 2010, Volume: 9, Issue:4

    Topics: Adipogenesis; Adiposity; Aging; Animals; Bone Marrow; Immunologic Memory; Ligands; Mice; Mice, Transgenic; PPAR gamma; Receptors, Antigen, T-Cell; Rosiglitazone; Thiazolidinediones; Thymus Gland

2010
Rosiglitazone attenuates the age-related changes in astrocytosis and the deficit in LTP.
    Neurobiology of aging, 2012, Volume: 33, Issue:1

    Topics: Aging; Animals; Astrocytes; Cells, Cultured; Endothelial Cells; Hippocampus; Hypoglycemic Agents; Inflammation Mediators; Long-Term Potentiation; Magnetic Resonance Imaging; Male; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2012
Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:6

    Topics: Aging; Animals; Antioxidants; Dietary Fats; Fatty Liver; Gene Expression; Hepatitis; Liver; Male; Metabolic Syndrome; Mice; Mice, Knockout; Mitochondria, Liver; Oxidative Stress; PPAR gamma; Receptors, LDL; Rosiglitazone; Thiazolidinediones

2010
Fish oil decreases inflammation and reduces cardiac remodeling in rosiglitazone treated aging mice.
    Pharmacological research, 2011, Volume: 63, Issue:4

    Topics: Aging; Animals; Collagen; Corn Oil; Diet; Female; Fish Oils; Heart; Hyperglycemia; Hypertrophy, Left Ventricular; Hypoglycemic Agents; Inflammation; Insulin Resistance; Mice; Mice, Inbred C57BL; Rosiglitazone; Thiazolidinediones; Ultrasonography

2011
Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes.
    Bone, 2012, Volume: 50, Issue:2

    Topics: Adipocytes; Adipose Tissue, Brown; Adiposity; Aging; Animals; Biomarkers; Bone and Bones; Bone Marrow; Cell Count; Diabetes Mellitus; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Phenotype; Rosiglitazone; Thiazolidinediones; Tibia

2012
Rosiglitazone enhances learning, place cell activity, and synaptic plasticity in middle-aged rats.
    Neurobiology of aging, 2012, Volume: 33, Issue:4

    Topics: Aging; Analysis of Variance; Animals; Biophysics; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glucose Transporter Type 3; Hippocampus; Hypoglycemic Agents; Long-Term Potentiation; Male; Maze Learning; Memory Disorders; Neurons; Rats; Rats, Wistar; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors

2012
Rosiglitazone improves contextual fear conditioning in aged rats.
    Neuroreport, 2004, Oct-05, Volume: 15, Issue:14

    Topics: Aging; Animals; Conditioning, Psychological; Fear; Male; Rats; Rats, Inbred F344; Rosiglitazone; Thiazolidinediones

2004
Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation.
    Endocrinology, 2005, Volume: 146, Issue:3

    Topics: Adipocytes; Aging; Animals; Bone and Bones; Cell Differentiation; Densitometry; Fatty Acids; Gene Expression Regulation; Hypoglycemic Agents; Ligands; Mesoderm; Mice; Osteoblasts; Osteoporosis; PPAR gamma; Rosiglitazone; Sp7 Transcription Factor; Stem Cells; Thiazolidinediones; Time Factors; Transcription Factors

2005
Regulation of the renal thiazide-sensitive Na-Cl cotransporter, blood pressure, and natriuresis in obese Zucker rats treated with rosiglitazone.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:2

    Topics: Aging; Animals; Blood Glucose; Blood Pressure; Body Weight; Glucose Tolerance Test; Hypoglycemic Agents; Immunoblotting; Immunoenzyme Techniques; Kidney; Male; Natriuresis; Obesity; PPAR gamma; Proteinuria; Rats; Rats, Zucker; Receptors, Drug; Rosiglitazone; Sodium Chloride; Sodium Chloride Symporters; Solute Carrier Family 12, Member 3; Symporters; Telemetry; Thiazolidinediones; Tissue Distribution

2005
Different response of senescent female Sprague-Dawley rats to gemfibrozil and rosiglitazone administration.
    Experimental gerontology, 2005, Volume: 40, Issue:7

    Topics: Adipose Tissue; Aging; Animals; Blood Glucose; Body Weight; Cholesterol; Diet; DNA-Binding Proteins; Fatty Acids, Nonesterified; Female; Gemfibrozil; Hepatocyte Nuclear Factor 4; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Leptin; Liver; Liver X Receptors; Orphan Nuclear Receptors; PPAR alpha; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Triglycerides

2005
Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone.
    Endocrinology, 2007, Volume: 148, Issue:6

    Topics: Aging; Animals; Bone and Bones; Bone Density; Bone Resorption; Cell Differentiation; Compressive Strength; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis; Rosiglitazone; Thiazolidinediones; Tomography, X-Ray Computed

2007
PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats.
    Bone, 2007, Volume: 41, Issue:4

    Topics: Aging; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Down-Regulation; Gene Expression Regulation, Enzymologic; Ligands; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoblasts; Osteogenesis; PPAR gamma; Prostaglandin D2; Rats; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors; Transforming Growth Factor beta

2007
Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:10

    Topics: Aging; Animals; Cardiomyopathy, Dilated; Fatty Acids; Gene Expression; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Glycogen; Heart; Lipid Metabolism; Mice; Mice, Transgenic; PPAR gamma; Promoter Regions, Genetic; Rosiglitazone; Thiazolidinediones; Ventricular Myosins

2007
Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain.
    Neurobiology of aging, 2009, Volume: 30, Issue:6

    Topics: Aging; Animals; Hippocampus; Interleukin-1beta; Interleukin-4; Male; Neuroprotective Agents; Nitric Oxide; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones

2009
Antidiabetic efficacy of BRL 49653, a potent orally active insulin sensitizing agent, assessed in the C57BL/KsJ db/db diabetic mouse by non-invasive 1H NMR studies of urine.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:3

    Topics: Administration, Oral; Aging; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycosuria; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Protons; Rosiglitazone; Thiazoles; Thiazolidinediones

1997
Developmental and pharmacological regulation of apolipoprotein C-II gene expression. Comparison with apo C-I and apo C-III gene regulation.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:1

    Topics: Aging; Animals; Apolipoprotein C-I; Apolipoprotein C-II; Apolipoprotein C-III; Apolipoproteins C; Fenofibrate; Gene Expression Regulation; Gene Expression Regulation, Developmental; Humans; Hypolipidemic Agents; Kinetics; Liver; Male; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides

1999
Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat.
    Diabetes, obesity & metabolism, 2000, Volume: 2, Issue:6

    Topics: Aging; Animals; Cataract; Diabetes Mellitus, Type 2; Glucagon; Hyperglycemia; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Pancreas; Proteinuria; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness; Thirst; Time Factors

2000
Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death.
    Diabetes, 2001, Volume: 50, Issue:5

    Topics: Aging; Animals; Blood Glucose; Body Weight; Cell Death; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Obesity; Organ Size; Pancreas; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones

2001