Page last updated: 2024-11-04

ropinirole and Pituitary Neoplasms

ropinirole has been researched along with Pituitary Neoplasms in 2 studies

Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.

Research Excerpts

ExcerptRelevanceReference
" The first patient, a 46-year-old man, was treated with ropinirole for restless legs syndrome and had lost huge amounts of money in the context of internet-based poker game."3.77[Pathological gambling induced by dopamine agonists]. ( Connemann, BJ; Gahr, M; Schönfeldt-Lecuona, CJ, 2011)
"7 h and exhibited a half-life of 5."2.90Pharmacokinetics and pharmacodynamics of ropinirole in patients with prolactinomas. ( Bies, R; Cremers, S; Hu, C; Liu, S; Page-Wilson, G; Peters, J; Tsang, A, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, S1
Hu, C1
Peters, J1
Tsang, A1
Cremers, S1
Bies, R1
Page-Wilson, G1
Gahr, M1
Connemann, BJ1
Schönfeldt-Lecuona, CJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Hyperprolactinemia With the Non-ergoline Dopamine Agonist Ropinirole: A Dose Escalation Study of Efficacy and Tolerability[NCT03038308]Phase 1/Phase 216 participants (Actual)Interventional2016-09-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Subjects With Unchanged Tumor Size

Radiologic assessment of tumor size before and after treatment will be made by MRI. (NCT03038308)
Timeframe: 6-12 months

InterventionParticipants (Count of Participants)
ROP Intervention7

Percentage of Subjects That Achieved Stable PRL Normalization

Serum prolactin concentrations (PRL levels) were measured in patients at baseline and at follow-up. (NCT03038308)
Timeframe: 6-12 months

Interventionpercentage of participants (Number)
ROP Intervention50

Trials

1 trial available for ropinirole and Pituitary Neoplasms

ArticleYear
Pharmacokinetics and pharmacodynamics of ropinirole in patients with prolactinomas.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:2

    Topics: Adult; Aged; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Indoles

2019

Other Studies

1 other study available for ropinirole and Pituitary Neoplasms

ArticleYear
[Pathological gambling induced by dopamine agonists].
    Fortschritte der Neurologie-Psychiatrie, 2011, Volume: 79, Issue:8

    Topics: Antiparkinson Agents; Cabergoline; Dopamine Agonists; Ergolines; Gambling; Humans; Indoles; Internat

2011