romurtide has been researched along with Herpes-Simplex* in 2 studies
1 review(s) available for romurtide and Herpes-Simplex
Article | Year |
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Stimulation of host-defense mechanism with synthetic adjuvants and recombinant cytokines against viral infection in mice.
The efficacy of synthetic immunoadjuvants and recombinant cytokines for the potentiation of host-resistance against virus infection was investigated using mouse models infected with Sendai virus and herpes simplex type 1 virus (HSV). The synthetic MDP derivative, MDP-Lys(L18), and recombinant cytokines, IL-1 beta, IFN-gamma, G-CSF and GM-CSF were shown to be effective for the stimulation of nonspecific protection against Sendai virus infection in mice. Both MDP-Lys(L18) and GM-CSF were effective for the protection against HSV infection in cyclophosphamide (CY)-treated mice. B30-MDP was suggested to be useful as an immunoadjuvant for the potentiation of antigenicity of recombinant or component vaccines. Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Amino Acid Sequence; Animals; Cytokines; Herpes Simplex; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Orthohantavirus; Parainfluenza Virus 1, Human; Paramyxoviridae Infections; Viral Envelope Proteins; Virus Diseases | 1992 |
1 other study(ies) available for romurtide and Herpes-Simplex
Article | Year |
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Effect of N alpha-acetylmuramyl-L-alanyl-D-isoglutaminyl-N epsilon-stearoyl- L-lysine on resistance to herpes simplex virus type-1 infection in cyclophosphamide-treated mice.
The restoration of resistance by N alpha-acetylmuramyl-L-alanyl-D-isoglutaminyl-N epsilon-stearoyl-L-lysine [MDP-Lys(L18)] on herpes simplex virus (HSV) type-1 infection was examined in cyclophosphamide (CY)-treated mice. MDP-Lys(L18) was shown to restore the resistance to HSV infection in CY-treated mice when it was injected either subcutaneously, intravenously, or intraperitoneally before infection. Treatment with MDP-Lys(L18) in CY-treated mice restored impaired activity for inhibiting HSV growth in the liver. Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Cell Line; Cyclophosphamide; Drug Resistance; Drug Resistance, Microbial; Herpes Simplex; Liver; Mice; Mice, Inbred BALB C; Simplexvirus; Time Factors | 1989 |