rome and Ventricular-Dysfunction--Left

rome has been researched along with Ventricular-Dysfunction--Left* in 2 studies

Other Studies

2 other study(ies) available for rome and Ventricular-Dysfunction--Left

ArticleYear
Outcomes of Surgery for Severe Aortic Regurgitation with Systolic Left Ventricular Dysfunction.
    The Journal of heart valve disease, 2017, Volume: 26, Issue:4

    Management of patients with aortic regurgitation (AR) and severe impairment of left ventricular (LV) function characterized by an ejection fraction (EF) ≤35% is challenging. Conflicting results regarding perioperative and long-term survival of these patients have been reported. The study aim was to compare in-hospital outcomes and long-term survival of patients with AR and severe LV dysfunction versus moderate dysfunction (35% 70 years and NYHA class III/IV symptoms were predictive of survival.. In-hospital and long-term survival was similar in patients with severe LV dysfunction and with preserved or moderately reduced LV function. Positive reverse LV remodelling and improved LV function was evident at the two-year echocardiographic follow up in these patients, who should not be denied aortic valve surgery.

    Topics: Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Insufficiency; Echocardiography; Female; Heart Valve Prosthesis Implantation; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Recovery of Function; Retrospective Studies; Risk Factors; Rome; Severity of Illness Index; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2017
Advanced Parameters of Cardiac Mechanics in Children with CKD: The 4C Study.
    Clinical journal of the American Society of Nephrology : CJASN, 2015, Aug-07, Volume: 10, Issue:8

    Newer parameters of cardiac mechanics provide additional insights on cardiac dysfunction in adult patients with CKD. The aim of this study was to identify prevalence of subclinical abnormalities in cardiac function through the analysis of novel indices of cardiac mechanics in a large population of children with CKD.. Between 2009 and 2011, the prospective observational Cardiovascular Comorbidity in Children with CKD Study enrolled patients with CKD ages 6-17 years old with eGFR=10-45 ml/min per 1.73 m(2) in 14 European countries. Cardiac morphology and function were assessed through echocardiography. The analysis presented encompasses global radial, longitudinal, and circumferential strains as well as time to peak analysis. Data were compared with 61 healthy children with comparable age and sex.. Data on 272 patients with CKD with complete echocardiographic assessment are reported (age =12.8±3.5 years old; 65% boys). Patients with CKD showed mildly higher office BP values and higher prevalence of left ventricular hypertrophy, but no differences were observed among groups in left ventricular ejection fraction. Strain analysis showed significantly lower global radial strain (29.6%±13.3% versus 35.5%±8.9%) and circumferential strain components (-21.8%±4.8% versus -28.2%±5.0%; both P<0.05) in patients with CKD without significant differences observed in longitudinal strain (-15.9%±3.4% versus -16.2%±3.7%). Lower values of global radial strain were associated with lower circumferential endocardial-to-epicardial gradient (r=0.51; P<0.01). This association remained significant after adjusting for BP, eGFR, and presence of left ventricular hypertrophy. Eventually, patients with CKD also showed higher delay in time to peak cardiac contraction (58±28 versus 37±18 milliseconds; P<0.05).. A significant proportion of children with CKD show impaired systolic mechanics. Impaired systolic function is characterized by lower radial strain, transmural circumferential gradient, and mild cardiac dyssynchrony. This study suggests that analysis of cardiac strain is feasible in a large multicenter study in children with CKD and provides additional information on cardiac pathophysiology of this high-risk population.

    Topics: Adolescent; Age Factors; Biomechanical Phenomena; Case-Control Studies; Child; Female; Humans; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Predictive Value of Tests; Prevalence; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors; Rome; Stress, Mechanical; Stroke Volume; Time Factors; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Function, Left

2015