rome and Hypercalcemia

rome has been researched along with Hypercalcemia* in 1 studies

Other Studies

1 other study(ies) available for rome and Hypercalcemia

ArticleYear
Chronic constipation in hypercalcemic patients with primary hyperparathyroidism.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:7

    Chronic constipation (C), among gastrointestinal symptoms, is commonly associated with primary hyperparathyroidism (PHPT) and probably attributable to hypercalcemia.. To evaluate in patients affected with PHPT the prevalence of C utilizing a validated questionnaire and the current prevalence of C compared to that observed in the past and to evaluate the relationship between C and the severity of PHPT.. 55 outpatients affected with PHPT, admitted to our Department of Internal Medicine and Medical Specialities in the years (2006-2009) were studied (group 1: 50 postmenopausal women and 5 men, mean age 61.9 +/- 9.4 years), together with 55 sex and age matched controls (group 2). Also considered were a group of PHPT patients observed, in the same ambulatory, during the years '70-'80 (group 3). A questionnaire, Rome II criteria, was administered and used to define C, whereas only anamneses were used to define C in group 3.. The prevalence of C in patients with PHPT was 21.8% in group 1 vs 12.7% in group 2 (n.s.) and 32.7% in group 3. There is a decreasing trend in the prevalence of C in patients with PHPT as observed from 1970-89 to 2006-2009 (p < 0.05). The reduction of C was associated together with a significant reduction in the serum calcium level (p < 0.001). The presence of C vs its absence in patients with PHPT is characterized by higher values of calcemia (p < 0.001), ionized calcium (p < 0.001), and parathyroid hormone (p = 0.019).. The actual prevalence of C in patients with PHPT is not significantly different from that found in the control group and is decreasing with respect to the past years. Moreover, C seems to be associated with the severity of the disease rather than with the diagnosis of PHPT per se.

    Topics: Aged; Case-Control Studies; Chi-Square Distribution; Chronic Disease; Constipation; Female; Humans; Hypercalcemia; Hyperparathyroidism, Primary; Male; Middle Aged; Prevalence; Risk Assessment; Risk Factors; Rome; Severity of Illness Index; Surveys and Questionnaires; Time Factors

2012