rolofylline has been researched along with Acute Disease in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 21 (95.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bloomfield, DM; Cleland, JGF; Cotter, G; Davison, B; Dittrich, HC; Givertz, MM; Hillege, HL; Liu, LCY; Metra, M; O'Connor, CM; Ponikowski, P; Postmus, D; Teerlink, JR; Valente, MAE; van der Meer, P; van Veldhuisen, DJ; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Cursack, GC; Davison, BA; Dittrich, HC; Edwards, C; Givertz, MM; Metra, M; Milo, O; O'Connor, CM; Ponikowski, P; Senger, S; Teerlink, JR; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Damman, K; Davison, B; Dittrich, HC; Fiuzat, M; Givertz, MM; Hillege, HL; Massie, BM; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Valente, MA; Van Veldhuisen, DJ; Voors, AA | 1 |
| Bloomfield, DM; Chiswell, K; Cleland, JG; Cotter, G; Davison, BA; Fiuzat, M; Givertz, MM; Grinfeld, L; Lotan, C; Mareev, V; Massie, BM; Mentz, RJ; Metra, M; O'Connor, CM; Ponikowski, P; Ruda, M; Stevens, SR; Teerlink, JR; Voors, AA | 1 |
| Bloomfield, DM; Chiswell, K; Cleland, JG; Cotter, G; Davison, BA; Dittrich, HC; Fiuzat, M; Givertz, MM; Lazzarini, V; Mansoor, GA; Massie, BM; Mentz, RJ; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Voors, AA | 1 |
| Cleland, JGF; Cotter, G; Davison, BA; Dittrich, HC; Edwards, C; Filippatos, G; Givertz, MM; Greenberg, B; Massie, BM; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Voors, AA | 1 |
| Berezikov, E; Bloomfield, DM; Bruno, N; Cleland, JG; Cotter, G; Davison, B; de Boer, RA; Dittrich, HC; Givertz, MM; Hillege, HL; Metra, M; O'Connor, CM; Ovchinnikova, ES; Pinto, YM; Ponikowski, P; Schmitter, D; Teerlink, JR; ter Maaten, JM; Valente, MA; van der Harst, P; van der Meer, P; van Veldhuisen, DJ; Vegter, EL; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Davison, BA; Dittrich, HC; Edwards, C; Givertz, MM; Massie, BM; Metra, M; Milo, O; O'Connor, CM; Ponikowski, P; Senger, S; Teerlink, JR; Voors, AA | 1 |
| Biegus, J; Bloomfield, DM; Cleland, JG; Cotter, G; Davison, BA; Dittrich, HC; Fiuzat, M; Givertz, MM; Hillege, HL; Massie, BM; Metra, M; O'Connor, CM; Ponikowski, P; Postmus, D; Teerlink, JR; Valente, MA; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Damman, K; Davison, B; Gheorghiade, M; Givertz, MM; Hillege, HL; Metra, M; O'Connor, CM; Ponikowski, P; Subacius, H; Teerlink, JR; Ter Maaten, JM; Valente, MA; van der Meer, P; van Veldhuisen, DJ; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Davison, B; Dittrich, HC; Givertz, MM; Hillege, HL; Mentz, RJ; Metra, M; Meyer, S; O'Connor, CM; Ponikowski, P; Teerlink, JR; Tromp, J; van der Meer, P; van Veldhuisen, DJ; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Damman, K; Davison, B; Givertz, MM; Hanberg, JS; Hillege, HL; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Ter Maaten, JM; Testani, JM; van Veldhuisen, DJ; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Davison, BA; Demissei, BG; Dittrich, HC; Edwards, C; Givertz, MM; Hillege, HL; Liu, LCY; Metra, M; O'Connor, CM; Ponikowski, P; Postmus, D; Teerlink, JR; Voors, AA | 1 |
| Berezikov, E; Bloomfield, D; Cleland, JG; Cotter, G; Davison, BA; Givertz, MM; Hagemeijer, Y; Khan, MA; Metra, M; O'Connor, CM; Ovchinnikova, ES; Ponikowski, P; Schmitter, D; Teerlink, JR; van der Harst, P; van der Meer, P; van Veldhuisen, DJ; Vegter, EL; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Damman, K; Davison, B; Dittrich, HC; Givertz, MM; Matsue, Y; Metra, M; O'Connor, CM; Ponikowski, P; Struck, J; Teerlink, JR; Ter Maaten, JM; van der Meer, P; van Veldhuisen, DJ; Voors, AA | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Damman, K; Davison, B; Dittrich, HC; Givertz, MM; Hillege, HL; Jaarsma, T; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Ter Maaten, JM; Tromp, J; van der Meer, P; van der Wal, MH; van Veldhuisen, DJ; Voors, AA | 1 |
| Bloomfield, DM; Cotter, G; Dittrich, HC; Massie, BM; Metra, M; O'Connor, CM; Weatherley, BD | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; DeLucca, P; Dittrich, HC; Givertz, MM; Mansoor, GA; Massie, BM; Metra, M; O'Connor, CM; Ponikowski, P; Salerno, CM; Teerlink, JR; Voors, A; Weatherley, BD | 1 |
| Bloomfield, DM; Cleland, JG; Cotter, G; Davison, BA; DeLucca, P; Dittrich, H; Givertz, MM; Jia, G; Mansoor, GA; Massie, B; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Voors, AA | 1 |
| Cleland, JG; Cotter, G; DeLucca, P; Dittrich, HC; Givertz, MM; Mansoor, GA; Massie, BM; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Voors, AA; Weatherley, BD | 1 |
| Bloomfield, D; Cleland, J; Cotter, G; Davison, BA; Delucca, P; Dittrich, HC; Fiuzat, M; Fujita, K; Givertz, MM; Jia, G; Lombardi, C; Mansoor, G; Massie, BM; Metra, M; O'Connor, CM; Ponikowski, P; Teerlink, JR; Voors, AA | 1 |
| Carson, PE; Cleland, JG; Cotter, G; Davison, BA; Delucca, P; Dittrich, H; Givertz, MM; Hauptman, PJ; Iragui, VJ; Lovett, DH; Mansoor, GA; Massie, BM; Metra, M; Miller, AB; Mohr, JP; O'Connor, CM; Piña, IL; Ponikowski, P; Salerno, CM; Teerlink, JR; Thomson, S; Varosy, PD; Voors, AA; Wolko, D; Zile, MR | 1 |
19 trial(s) available for rolofylline and Acute Disease
| Article | Year |
|---|---|
Identifying Subpopulations with Distinct Response to Treatment Using Plasma Biomarkers in Acute Heart Failure: Results from the PROTECT Trial : Differential Response in Acute Heart Failure.
Topics: Acute Disease; Aged; Biomarkers; Diuretics; Female; Heart Failure; Humans; Male; Xanthines | 2017 |
Diuretic response in acute heart failure: clinical characteristics and prognostic significance.
Topics: Acute Disease; Aged; Analysis of Variance; Atherosclerosis; Bumetanide; Diabetes Complications; Diuretics; Dose-Response Relationship, Drug; Drug Resistance; Dyspnea; Female; Furosemide; Heart Failure; Humans; Hypotension; Male; Patient Readmission; Renal Insufficiency; Sulfonamides; Torsemide; Treatment Outcome; Weight Loss; Xanthines | 2014 |
International differences in clinical characteristics, management, and outcomes in acute heart failure patients: better short-term outcomes in patients enrolled in Eastern Europe and Russia in the PROTECT trial.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Aged; Aged, 80 and over; Diuretics; Europe, Eastern; Female; Geography; Heart Failure; Hospitalization; Humans; Internationality; Length of Stay; Male; Middle Aged; Quality of Life; Russia; Xanthines | 2014 |
Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Diuretics; Double-Blind Method; Female; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; Severity of Illness Index; Sodium; Treatment Outcome; Xanthines | 2015 |
Worsening Heart Failure Following Admission for Acute Heart Failure: A Pooled Analysis of the PROTECT and RELAX-AHF Studies.
Topics: Acute Disease; Disease Progression; Diuretics; Double-Blind Method; Female; Heart Failure; Hospitalization; Humans; Male; Prognosis; Relaxin; Treatment Outcome; Xanthines | 2015 |
MicroRNAs relate to early worsening of renal function in patients with acute heart failure.
Topics: Acute Disease; Aged; Biomarkers; Creatinine; Disease Progression; Diuretics; Double-Blind Method; Early Diagnosis; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Gene Expression Regulation; Glomerular Filtration Rate; Heart Failure; Humans; Male; MicroRNAs; Real-Time Polymerase Chain Reaction; Renal Insufficiency; Retrospective Studies; Xanthines | 2016 |
Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure.
Topics: Acute Disease; Aged; Aged, 80 and over; Benzazepines; Biomarkers; Decision Support Techniques; Diuresis; Diuretics; Female; Furosemide; Heart Failure; Hemoglobins; Humans; Kaplan-Meier Estimate; Kidney; Male; Middle Aged; Patient Readmission; Predictive Value of Tests; Reproducibility of Results; Risk Assessment; Risk Factors; Time Factors; Tolvaptan; Treatment Outcome; Xanthines | 2016 |
Acute heart failure in the young: Clinical characteristics and biomarker profiles.
Topics: Acute Disease; Biomarkers; Comorbidity; Diuretics; Female; Heart Failure; Hospitalization; Humans; Kidney Function Tests; Long Term Adverse Effects; Male; Medication Therapy Management; Middle Aged; Outcome and Process Assessment, Health Care; Severity of Illness Index; Stroke Volume; Symptom Assessment; Xanthines | 2016 |
Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure.
Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Chlorides; Disease Progression; Diuretics; Down-Regulation; Drug Resistance; Female; Heart Failure; Hospitalization; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Risk Factors; Time Factors; Treatment Outcome; Xanthines | 2016 |
Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure - Post-hoc analysis of the PROTECT trial.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Aged; Diuretics; Double-Blind Method; Female; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Patient Acuity; Protective Agents; Reproducibility of Results; Risk Assessment; Treatment Outcome; Xanthines | 2016 |
Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure.
Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Databases, Factual; Diuretics; Female; Heart Failure; Hospitalization; Humans; Male; MicroRNAs; Middle Aged; Xanthines | 2016 |
Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure.
Topics: Acute Disease; Biomarkers; Enkephalins; Female; Glomerular Filtration Rate; Heart Failure; Humans; Kidney; Male; Middle Aged; Predictive Value of Tests; Prognosis; Protein Precursors; Xanthines | 2017 |
Serum Potassium Levels and Outcome in Acute Heart Failure (Data from the PROTECT and COACH Trials).
Topics: Acute Disease; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Cohort Studies; Diuretics; Female; Heart Failure; Hospitalization; Humans; Kidney; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Reproducibility of Results; Treatment Outcome; Xanthines | 2017 |
The PROTECT pilot study: a randomized, placebo-controlled, dose-finding study of the adenosine A1 receptor antagonist rolofylline in patients with acute heart failure and renal impairment.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Aged; Cardiovascular Agents; Confidence Intervals; Disease Progression; Diuresis; Dyspnea; Female; Heart Failure; Humans; Male; Pilot Projects; Renal Insufficiency; Risk; Risk Factors; Xanthines | 2008 |
Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Aged; Diuretics; Double-Blind Method; Female; Heart Failure; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Male; Odds Ratio; Patient Readmission; Proportional Hazards Models; Risk; Treatment Failure; Xanthines | 2010 |
Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Aged; Aged, 80 and over; Double-Blind Method; Dyspnea; Female; Heart Failure; Humans; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Prospective Studies; Treatment Outcome; Xanthines | 2011 |
Effects of the adenosine A1 receptor antagonist rolofylline on renal function in patients with acute heart failure and renal dysfunction: results from PROTECT (Placebo-Controlled Randomized Study of the Selective Adenosine A1 Receptor Antagonist Rolofylli
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Double-Blind Method; Female; Heart Failure; Hospitalization; Humans; Kidney; Kidney Diseases; Male; Pilot Projects; Stroke Volume; Treatment Outcome; Xanthines | 2011 |
Impact of serial troponin release on outcomes in patients with acute heart failure: analysis from the PROTECT pilot study.
Topics: Acute Disease; Aged; Biomarkers; Double-Blind Method; Female; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Myocardium; Pilot Projects; Predictive Value of Tests; Prognosis; Purinergic P1 Receptor Antagonists; Time Factors; Treatment Outcome; Troponin; Xanthines | 2011 |
The safety of an adenosine A(1)-receptor antagonist, rolofylline, in patients with acute heart failure and renal impairment: findings from PROTECT.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Aged; Aged, 80 and over; Female; Follow-Up Studies; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Renal Insufficiency; Risk Factors; Stroke; Time Factors; Xanthines | 2012 |
3 other study(ies) available for rolofylline and Acute Disease
| Article | Year |
|---|---|
Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion: A Post Hoc Analysis of the PROTECT Data.
Topics: Acute Disease; Aged; Aged, 80 and over; Creatinine; Female; Heart Failure; Hospitalization; Humans; Kidney; Male; Middle Aged; Patient Readmission; Prognosis; Proportional Hazards Models; Xanthines | 2018 |
Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality.
Topics: Acute Disease; Aged; Comorbidity; Diabetes Mellitus; Disease Progression; Diuretics; Edema; Female; Heart Failure; Hospitalization; Humans; Length of Stay; Logistic Models; Male; Middle Aged; Mortality; Multivariate Analysis; Myocardial Ischemia; Odds Ratio; Patient Readmission; Proportional Hazards Models; Randomized Controlled Trials as Topic; Renal Insufficiency; Severity of Illness Index; Xanthines | 2016 |
Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study.
Topics: Acute Disease; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Disease Progression; Diuretics; Female; Heart Failure; Humans; Liver Function Tests; Male; Middle Aged; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Serum Albumin; Xanthines | 2016 |