rolitetracycline and Postoperative-Complications

The role of antibiotics in the treatment and prevention of postoperative spondylodiscitis is still controversial. In a group of 15 patients operated on account of lumbar discopathy, the authors investigated the penetration of antibiotics into the intervertebral disc, in correlation to serum levels, when antibiotics were administered during operation. Despite high serum levels rolitetracycline was not detected in extirpated material of the disc, gentamycin reached 2-6% serum levels. The authors give an account of views on the role of antibiotics in the prophylaxis of postoperative spondylodiscitis and recommend their administration in particular in risk groups. They recommend antibiotics in case of early diagnosis of postoperative spondylodiscitis, in the later stages of the disease the role of antibiotics is controversial.

Topics: Discitis; Gentamicins; Humans; Intervertebral Disc; Postoperative Complications; Premedication; Rolitetracycline

Gelatine sponge packs (Marbagelan) saturated in rolitetracycline (Reverin) were evaluated. The antimicrobiotic efficacy of the substance was determined in 26 packs before insertion and in 20 packs removed from the external ear meatus after varying periods. High concentrations of rolitetracycline were found independent of saturation grade in the packs before insertion. In the packs removed from the external meatus acceptable antimicrobial activity was found independent of the time the packs remained in the ear. An efficient prophylaxis against infection in ear surgery is guaranteed.

Topics: Ear, Middle; Gelatin; Humans; Infection Control; Postoperative Complications; Rolitetracycline; Tampons, Surgical; Time Factors; Tympanoplasty

Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Appendectomy; Appendicitis; Child; Child, Preschool; Drainage; Female; Humans; Intestinal Obstruction; Intestinal Perforation; Male; Postoperative Complications; Rolitetracycline; Surgical Wound Infection; Therapeutic Irrigation

Topics: Humans; Orthopedics; Postoperative Complications; Rolitetracycline; Surgical Wound Infection

Topics: Adult; Chloramphenicol; Diagnosis, Differential; Female; Gangrene; Humans; Leg Dermatoses; Penicillins; Postoperative Complications; Pyoderma; Rolitetracycline; Skin; Terminology as Topic; Triamcinolone; Varicose Veins

Topics: Female; Follow-Up Studies; Humans; Hydrocortisone; Injections, Intraperitoneal; Pelvis; Postoperative Complications; Pregnancy; Pregnancy, Ectopic; Rolitetracycline; Tissue Adhesions

Topics: Chloramphenicol; Humans; Inflammation; Postoperative Complications; Rolitetracycline; Surgical Wound Infection

Topics: Anti-Bacterial Agents; Humans; Postoperative Complications; Rolitetracycline; Sepsis; Tetracycline; Tooth Extraction

Topics: Cavernous Sinus Thrombosis; Drug Therapy; Erythromycin; Heparin; History; Humans; Hydrocortisone; Penicillins; Postoperative Complications; Prednisolone; Rolitetracycline; Sepsis; Sinus Thrombosis, Intracranial; Tooth Extraction

Topics: Abdomen; Anti-Bacterial Agents; Autopsy; Enterocolitis, Pseudomembranous; Humans; Postoperative Complications; Rolitetracycline

Topics: Appendicitis; Cholangitis; Cholecystitis; Gangrene; Humans; Intestinal Obstruction; Intestinal Perforation; Osteomyelitis; Pancreatitis; Peptic Ulcer Perforation; Peritonitis; Postoperative Complications; Rolitetracycline; Sepsis; Surgical Procedures, Operative

Topics: Diarrhea; Enterocolitis; Humans; Postoperative Complications; Rolitetracycline; Toxicology