Page last updated: 2024-11-04

rolipram and Subarachnoid Hemorrhage

rolipram has been researched along with Subarachnoid Hemorrhage in 3 studies

Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.

Research Excerpts

ExcerptRelevanceReference
"Rolipram treatment remarkably promoted the expression of Sirtuin 1 (SIRT1) while inhibited NF-κB activation."5.48Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway. ( Chen, G; Chen, T; Fan, L; He, P; Jin, J; Li, J; Peng, Y; Ruan, W; Xu, H, 2018)
"Rolipram treatment remarkably promoted the expression of Sirtuin 1 (SIRT1) while inhibited NF-κB activation."1.48Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway. ( Chen, G; Chen, T; Fan, L; He, P; Jin, J; Li, J; Peng, Y; Ruan, W; Xu, H, 2018)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peng, Y2
Jin, J1
Fan, L2
Xu, H2
He, P2
Li, J2
Chen, T2
Ruan, W2
Chen, G2
Li, Q1
Cao, S1
Willette, RN1
Shiloh, AO1
Sauermelch, CF1
Sulpizio, A1
Michell, MP1
Cieslinski, LB1
Torphy, TJ1
Ohlstein, EH1

Other Studies

3 other studies available for rolipram and Subarachnoid Hemorrhage

ArticleYear
Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway.
    Neurochemical research, 2018, Volume: 43, Issue:4

    Topics: Animals; Brain Injuries; Injections, Intraperitoneal; Male; Neuroprotective Agents; NF-kappa B; Phos

2018
Phosphodiesterase-4 inhibition confers a neuroprotective efficacy against early brain injury following experimental subarachnoid hemorrhage in rats by attenuating neuronal apoptosis through the SIRT1/Akt pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Animals; Apoptosis; Benzamides; Brain Edema; Brain Injuries; Cyclic Nucleotide Phosphodiesterases, T

2018
Identification, characterization, and functional role of phosphodiesterase type IV in cerebral vessels: effects of selective phosphodiesterase inhibitors.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-AMP Phosphodiestera

1997