rolipram has been researched along with Schizophrenia in 5 studies
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The indirect DA agonist amphetamine has been used to model the auditory sensory processing deficits in schizophrenia." | 3.72 | Phosphodiesterase inhibitors: a novel mechanism for receptor-independent antipsychotic medications. ( Abel, T; Kanes, SJ; Maxwell, CR; Siegel, SJ, 2004) |
| "Rolipram has a pharmacologic profile similar to that of the atypical antipsychotics and has low extrapyramidal symptom liability." | 1.34 | Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme. ( Chapin, DS; Martin, AN; McCarthy, SA; Siuciak, JA, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, NS | 1 |
| Wen, Z | 1 |
| Liu, J | 1 |
| Zhou, Y | 1 |
| Guo, Z | 1 |
| Xu, C | 1 |
| Lin, YT | 1 |
| Yoon, KJ | 1 |
| Park, J | 1 |
| Cho, M | 1 |
| Kim, M | 1 |
| Wang, X | 1 |
| Yu, H | 1 |
| Sakamuru, S | 1 |
| Christian, KM | 1 |
| Hsu, KS | 1 |
| Xia, M | 1 |
| Li, W | 1 |
| Ross, CA | 1 |
| Margolis, RL | 1 |
| Lu, XY | 1 |
| Song, H | 1 |
| Ming, GL | 1 |
| Kuroiwa, M | 1 |
| Snyder, GL | 1 |
| Shuto, T | 1 |
| Fukuda, A | 1 |
| Yanagawa, Y | 1 |
| Benavides, DR | 1 |
| Nairn, AC | 1 |
| Bibb, JA | 1 |
| Greengard, P | 1 |
| Nishi, A | 1 |
| Maxwell, CR | 1 |
| Kanes, SJ | 1 |
| Abel, T | 1 |
| Siegel, SJ | 1 |
| Davis, JA | 1 |
| Gould, TJ | 1 |
| Siuciak, JA | 1 |
| Chapin, DS | 1 |
| McCarthy, SA | 1 |
| Martin, AN | 1 |
5 other studies available for rolipram and Schizophrenia
| Article | Year |
|---|---|
Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Mo | 2021 |
Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dopamin | 2012 |
Phosphodiesterase inhibitors: a novel mechanism for receptor-independent antipsychotic medications.
Topics: Amphetamine; Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine; Dopamine Agents; Evoke | 2004 |
Rolipram attenuates MK-801-induced deficits in latent inhibition.
Topics: Animals; Cyclic AMP; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; | 2005 |
Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, An | 2007 |