rolipram has been researched along with Reperfusion Injury in 9 studies
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effect of Rolipram, a phosphodiesterase-4-inhibitor, on renal ischemia-reperfusion injury (IRI) in rats." | 7.78 | Protective effects of phosphodiesterase-4-specific inhibitor rolipram on acute ischemia-reperfusion injury in rat kidney. ( Abat, D; Acikalin, A; Aridogan, IA; Bayazit, Y; Izol, V; Mammadov, E; Tuli, A, 2012) |
| "In lungs from nonventilated, circulation-arrested donors, reperfusion with rolipram reduces the ischemia-reperfusion injury that may be due to intracellular cyclic adenosine monophosphate." | 7.70 | Reduced ischemia-reperfusion injury with rolipram in rat cadaver lung donors: effect of cyclic adenosine monophosphate. ( Becker, RM; Bleiweis, MS; Egan, TM; Hoffmann, SC; Jones, DR, 1999) |
| "Rolipram failed to increase perfusate cAMP alone but dramatically increased perfusate cAMP above ISO alone." | 5.29 | Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor. ( Barnard, JW; Prasad, VR; Seibert, AF; Smart, DA; Strada, SJ; Taylor, AE; Thompson, WJ, 1994) |
| "To investigate the effect of Rolipram, a phosphodiesterase-4-inhibitor, on renal ischemia-reperfusion injury (IRI) in rats." | 3.78 | Protective effects of phosphodiesterase-4-specific inhibitor rolipram on acute ischemia-reperfusion injury in rat kidney. ( Abat, D; Acikalin, A; Aridogan, IA; Bayazit, Y; Izol, V; Mammadov, E; Tuli, A, 2012) |
| "In lungs from nonventilated, circulation-arrested donors, reperfusion with rolipram reduces the ischemia-reperfusion injury that may be due to intracellular cyclic adenosine monophosphate." | 3.70 | Reduced ischemia-reperfusion injury with rolipram in rat cadaver lung donors: effect of cyclic adenosine monophosphate. ( Becker, RM; Bleiweis, MS; Egan, TM; Hoffmann, SC; Jones, DR, 1999) |
| "Rolipram failed to increase perfusate cAMP alone but dramatically increased perfusate cAMP above ISO alone." | 1.29 | Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor. ( Barnard, JW; Prasad, VR; Seibert, AF; Smart, DA; Strada, SJ; Taylor, AE; Thompson, WJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mammadov, E | 1 |
| Aridogan, IA | 1 |
| Izol, V | 1 |
| Acikalin, A | 1 |
| Abat, D | 1 |
| Tuli, A | 1 |
| Bayazit, Y | 1 |
| Schütte, H | 1 |
| Schell, A | 1 |
| Schäfer, C | 1 |
| Ghofrani, A | 1 |
| Theo Schermuly, R | 1 |
| Seeger, W | 1 |
| Grimminger, F | 1 |
| Kyoi, T | 1 |
| Kitazawa, S | 1 |
| Tajima, K | 1 |
| Zhang, X | 1 |
| Ukai, Y | 1 |
| Barnard, JW | 1 |
| Seibert, AF | 1 |
| Prasad, VR | 1 |
| Smart, DA | 1 |
| Strada, SJ | 1 |
| Taylor, AE | 1 |
| Thompson, WJ | 1 |
| Bleiweis, MS | 2 |
| Jones, DR | 2 |
| Hoffmann, SC | 2 |
| Becker, RM | 1 |
| Egan, TM | 2 |
| Featherstone, RL | 1 |
| Chambers, DJ | 1 |
| Kelly, FJ | 1 |
| Okusa, MD | 1 |
| Linden, J | 1 |
| Huang, L | 1 |
| Rosin, DL | 1 |
| Smith, DF | 1 |
| Sullivan, G | 1 |
| Paik, HC | 1 |
| Ciriaco, P | 1 |
| Souza, DG | 1 |
| Cassali, GD | 1 |
| Poole, S | 1 |
| Teixeira, MM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Aminophylline on Preventing Acute Kidney Injury in Pediatric Patients Undergoing Open Heart Surgery[NCT03897335] | Phase 3 | 80 participants (Anticipated) | Interventional | 2019-02-07 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for rolipram and Reperfusion Injury
| Article | Year |
|---|---|
Protective effects of phosphodiesterase-4-specific inhibitor rolipram on acute ischemia-reperfusion injury in rat kidney.
Topics: Animals; Catalase; Kidney Diseases; Lipid Peroxidation; Malondialdehyde; Phosphodiesterase 4 Inhibit | 2012 |
Subthreshold doses of nebulized prostacyclin and rolipram synergistaically protect against lung ischemia-reperfusion.
Topics: Animals; Capillary Permeability; Cyclic AMP; Disease Models, Animal; Drug Synergism; Epoprostenol; F | 2003 |
Phosphodiesterase type IV inhibitors prevent ischemia-reperfusion-induced gastric injury in rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Anti-U | 2004 |
Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenylyl Cyclases; Animals; Capillary Permeability; Co | 1994 |
Reduced ischemia-reperfusion injury with rolipram in rat cadaver lung donors: effect of cyclic adenosine monophosphate.
Topics: Adenine Nucleotides; Animals; Capillary Permeability; Chromatography, High Pressure Liquid; Cyclic A | 1999 |
Comparison of phosphodiesterase inhibitors of differing isoenzyme selectivity added to St. Thomas' hospital cardioplegic solution used for hypothermic preservation of rat lungs.
Topics: Animals; Bicarbonates; Calcium Chloride; Hypothermia, Induced; Lung; Lung Transplantation; Magnesium | 2000 |
Enhanced protection from renal ischemia-reperfusion [correction of ischemia:reperfusion] injury with A(2A)-adenosine receptor activation and PDE 4 inhibition.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acute Kidney Injury; Animals; Cyclic AMP; Cyclic AMP-Dependent | 2001 |
Maintenance of cAMP in non-heart-beating donor lungs reduces ischemia-reperfusion injury.
Topics: Adenine Nucleotides; Adrenergic beta-Agonists; Animals; Blood Pressure; Cadaver; Capillary Permeabil | 2001 |
Effects of inhibition of PDE4 and TNF-alpha on local and remote injuries following ischaemia and reperfusion injury.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Capillary Permeability; Cyclic Nucleotide Phosphodiest | 2001 |