Page last updated: 2024-11-04

rolipram and Pulmonary Hypertension

rolipram has been researched along with Pulmonary Hypertension in 5 studies

Research Excerpts

ExcerptRelevanceReference
"1% when administered intravenously at 30 microg/kg to the chronically hypoxic rats and had an apparent oral bioavailability of about 19."1.314-(3-Chloro-4-methoxybenzyl)aminophthalazines: synthesis and inhibitory activity toward phosphodiesterase 5. ( Adachi, H; Ishibashi, K; Ishihara, H; Kabasawa, Y; Kakiki, M; Kodama, K; Matsukura, M; Miyazaki, K; Nishino, M; Ozaki, H; Takase, Y; Watanabe, N, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watanabe, N1
Adachi, H1
Takase, Y1
Ozaki, H1
Matsukura, M1
Miyazaki, K1
Ishibashi, K1
Ishihara, H1
Kodama, K1
Nishino, M1
Kakiki, M1
Kabasawa, Y1
De Franceschi, L1
Platt, OS1
Malpeli, G1
Janin, A1
Scarpa, A1
Leboeuf, C1
Beuzard, Y1
Payen, E1
Brugnara, C1
Schermuly, RT2
Ghofrani, HA2
Enke, B1
Weissmann, N2
Grimminger, F2
Seeger, W2
Schudt, C2
Walmrath, D2
Roehl, A1
Tenor, H1
Champion, HC1
Bivalacqua, TJ1
Toyoda, K1
Heistad, DD1
Hyman, AL1
Kadowitz, PJ1

Other Studies

5 other studies available for rolipram and Pulmonary Hypertension

ArticleYear
4-(3-Chloro-4-methoxybenzyl)aminophthalazines: synthesis and inhibitory activity toward phosphodiesterase 5.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antihypertensive Agents; Biological Availability; Bloo

2000
Protective effects of phosphodiesterase-4 (PDE-4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Mice; Mice,

2008
Low-dose systemic phosphodiesterase inhibitors amplify the pulmonary vasodilatory response to inhaled prostacyclin in experimental pulmonary hypertension.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:5 Pt 1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Aero

1999
Subthreshold doses of specific phosphodiesterase type 3 and 4 inhibitors enhance the pulmonary vasodilatory response to nebulized prostacyclin with improvement in gas exchange.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aerosols; Animals; Antihypertens

2000
In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse.
    Circulation, 2000, Feb-29, Volume: 101, Issue:8

    Topics: Adenoviridae; Adrenomedullin; Animals; beta-Galactosidase; Calcitonin Gene-Related Peptide; Cyclic A

2000