rolipram has been researched along with Pulmonary Fibrosis in 2 studies
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Roflumilast was approximately 10-fold more potent than rolipram." | 1.35 | PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts. ( Ahn, Y; Ertl, RF; Fredriksson, K; Holz, O; Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Magnussen, H; Rennard, SI; Skold, CM; Sugiura, H; Togo, S; Wang, X, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Togo, S | 1 |
| Liu, X | 1 |
| Wang, X | 1 |
| Sugiura, H | 1 |
| Kamio, K | 1 |
| Kawasaki, S | 1 |
| Kobayashi, T | 1 |
| Ertl, RF | 1 |
| Ahn, Y | 1 |
| Holz, O | 1 |
| Magnussen, H | 1 |
| Fredriksson, K | 1 |
| Skold, CM | 1 |
| Rennard, SI | 1 |
| de Visser, YP | 1 |
| Walther, FJ | 1 |
| Laghmani, EH | 1 |
| van Wijngaarden, S | 1 |
| Nieuwland, K | 1 |
| Wagenaar, GT | 1 |
2 other studies available for rolipram and Pulmonary Fibrosis
| Article | Year |
|---|---|
PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts.
Topics: Adult; Aminopyridines; Benzamides; Cells, Cultured; Chemotaxis; Collagen; Cyclic AMP; Cyclic Nucleot | 2009 |
Phosphodiesterase-4 inhibition attenuates pulmonary inflammation in neonatal lung injury.
Topics: Animals; Animals, Newborn; Benzamides; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Ex | 2008 |