rolipram has been researched along with Psychotic Disorders in 3 studies
Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rolipram has antipsychotic properties." | 1.38 | PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis. ( Manahan-Vaughan, D; Wiescholleck, V, 2012) |
| "Rolipram has a pharmacologic profile similar to that of the atypical antipsychotics and has low extrapyramidal symptom liability." | 1.34 | Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme. ( Chapin, DS; Martin, AN; McCarthy, SA; Siuciak, JA, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wiescholleck, V | 1 |
| Manahan-Vaughan, D | 1 |
| Siuciak, JA | 1 |
| Chapin, DS | 1 |
| McCarthy, SA | 1 |
| Martin, AN | 1 |
| Inada, T | 1 |
| Yagi, G | 1 |
1 review available for rolipram and Psychotic Disorders
| Article | Year |
|---|---|
Current topics in tardive dyskinesia in Japan.
Topics: Antipsychotic Agents; Central Nervous System Agents; Ceruletide; Clinical Trials as Topic; Cross-Cul | 1995 |
2 other studies available for rolipram and Psychotic Disorders
| Article | Year |
|---|---|
PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis.
Topics: Animals; Antipsychotic Agents; Cyclic AMP; Disease Models, Animal; Dizocilpine Maleate; Dose-Respons | 2012 |
Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, An | 2007 |