rolipram has been researched along with Muscle Relaxation in 45 studies
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The involvement of cyclic AMP-dependent protein kinase (PKA) and cyclic GMP-dependent protein kinase (PKC) in the effects of cyclic AMP-elevating agents on vascular smooth muscle relaxation, cyclic nucleotide dependent-protein kinase activities and ATP-induced calcium signalling ([Ca2+]i was studied in rat aorta." | 3.69 | Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation. ( Eckly-Michel, A; Lugnier, C; Martin, V, 1997) |
| "Rolipram caused an increase in the frequency of Ca(2+) sparks and the spontaneous transient BK currents (TBKCs), hyperpolarized the cell membrane potential (MP), and decreased the intracellular Ca(2+) levels." | 1.40 | BK channel-mediated relaxation of urinary bladder smooth muscle: a novel paradigm for phosphodiesterase type 4 regulation of bladder function. ( Cheng, Q; Li, N; Petkov, GV; Xin, W, 2014) |
| " CRH with P4 pretreatment caused a 40 +/- 13% (n = 4) reduction in contractility, whereas in matched samples, CRH alone exerted a 26 +/- 6% (n = 4) reduction, with a shift of CRH dose-response curves (P < 0." | 1.35 | Evidence that corticotropin-releasing hormone modulates myometrial contractility during human pregnancy. ( Read, M; Smith, R; Tyson, EK, 2009) |
| "Detrusor smooth muscle relaxation is mainly mediated by the cyclic adenosine monophosphate (cAMP) pathway." | 1.34 | Relaxation of phasic contractile activity of human detrusor strips by cyclic nucleotide phosphodiesterase type 4 inhibition. ( Alexandre, L; Behr-Roussel, D; Denys, P; Giuliano, F; Gorny, D; Lebret, T; Oger, S, 2007) |
| "1% when administered intravenously at 30 microg/kg to the chronically hypoxic rats and had an apparent oral bioavailability of about 19." | 1.31 | 4-(3-Chloro-4-methoxybenzyl)aminophthalazines: synthesis and inhibitory activity toward phosphodiesterase 5. ( Adachi, H; Ishibashi, K; Ishihara, H; Kabasawa, Y; Kakiki, M; Kodama, K; Matsukura, M; Miyazaki, K; Nishino, M; Ozaki, H; Takase, Y; Watanabe, N, 2000) |
| " Among them, 3,4-dipropyl-4,5,7,8-tetrahydro-3H-imidazo[1,2-i]-purin-5-one (1c), which was the most selective and potent PDE IV inhibitor, did not cause emesis in Suncus murinus at a dosage range of 10-100 mg/kg (po), while an imidazole analogue of 1c (4c) and known PDE IV inhibitors such as rolipram and denbufylline caused emesis even at 10 or 30 mg/kg." | 1.30 | Selective inhibitors of cyclic AMP-specific phosphodiesterase: heterocycle-condensed purines. ( Kasugai, S; Miyamoto, K; Ohya, K; Sawanishi, H; Suzuki, H; Suzuki, N; Takagi, K; Waki, Y; Yamamoto, S, 1997) |
| "2." | 1.29 | Possible role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane generation and airways smooth muscle tone. ( Giembycz, MA; Raeburn, D; Scott, LC; Souness, JE; Tomkinson, A; Villamil, ME, 1994) |
| "Siguazodan was 100 fold more active than rolipram in pig tissues indicating the type III isoenzyme may be of greater functional significance in this tissue." | 1.29 | Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes. ( Karlsson, JA; Raeburn, D; Tomkinson, A, 1993) |
| ") did not bronchodilate but caused a parallel 7 fold rightward shift in the histamine dose-response curve." | 1.29 | Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor. ( Gozzard, N; Higgs, G; Holbrook, M; Hughes, B; James, T, 1996) |
| "Rolipram was an effective inhibitor of superoxide generation and elastase release (-log IC50 values approximately 8) while SKF94120 and levcromakalim were scarcely effective." | 1.29 | Effects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: comparison with rolipram, SKF94120 and levcromakalim. ( Berto, L; Bonnet, PA; Cortijo, J; Michel, A; Morcillo, EJ; Navarrete, C; Sanz, C; Villagrasa, V, 1996) |
| "When OPC 3911 or milrinone was combined with rolipram more than additive effects on aortic relaxation and cAMP content were obtained." | 1.28 | Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta. ( Andersson, KE; Degerman, E; Lindgren, S; Manganiello, V; Rascón, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 26 (57.78) | 18.2507 |
| 2000's | 13 (28.89) | 29.6817 |
| 2010's | 6 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suzuki, F | 1 |
| Kuroda, T | 1 |
| Kawakita, T | 1 |
| Manabe, H | 1 |
| Kitamura, S | 1 |
| Ohmori, K | 1 |
| Ichimura, M | 1 |
| Kase, H | 1 |
| Ichikawa, S | 1 |
| Sawanishi, H | 1 |
| Suzuki, H | 1 |
| Yamamoto, S | 1 |
| Waki, Y | 1 |
| Kasugai, S | 1 |
| Ohya, K | 1 |
| Suzuki, N | 1 |
| Miyamoto, K | 1 |
| Takagi, K | 1 |
| Watanabe, N | 1 |
| Adachi, H | 1 |
| Takase, Y | 1 |
| Ozaki, H | 1 |
| Matsukura, M | 1 |
| Miyazaki, K | 1 |
| Ishibashi, K | 1 |
| Ishihara, H | 1 |
| Kodama, K | 1 |
| Nishino, M | 1 |
| Kakiki, M | 1 |
| Kabasawa, Y | 1 |
| Kim, E | 1 |
| Chun, HO | 1 |
| Jung, SH | 1 |
| Kim, JH | 1 |
| Lee, JM | 1 |
| Suh, BC | 1 |
| Xiang, MX | 1 |
| Rhee, CK | 1 |
| Agis-Torres, Á | 1 |
| Recio, P | 1 |
| López-Oliva, ME | 1 |
| Martínez, MP | 1 |
| Barahona, MV | 2 |
| Benedito, S | 1 |
| Bustamante, S | 2 |
| Jiménez-Cidre, MÁ | 1 |
| García-Sacristán, A | 2 |
| Prieto, D | 2 |
| Fernandes, VS | 2 |
| Hernández, M | 2 |
| Tsai, CC | 1 |
| Tey, SL | 1 |
| Chang, LC | 1 |
| Su, YT | 1 |
| Lin, KJ | 1 |
| Huang, SC | 1 |
| Linhares, BL | 1 |
| Nascimento, NRF | 1 |
| Gonzaga-Silva, LF | 1 |
| Santos, CF | 1 |
| Moraes, MO | 1 |
| Marinho, LB | 1 |
| Silva, APG | 1 |
| Fonteles, MC | 1 |
| Reges, R | 1 |
| Xin, W | 1 |
| Li, N | 1 |
| Cheng, Q | 1 |
| Petkov, GV | 1 |
| Ribeiro, ASF | 1 |
| Martínez-Sáenz, A | 1 |
| Martínez, P | 1 |
| Orensanz, LM | 1 |
| Blaha, I | 1 |
| Serrano-Margüello, D | 1 |
| Carballido, J | 1 |
| Tyson, EK | 2 |
| Macintyre, DA | 1 |
| Smith, R | 2 |
| Chan, EC | 1 |
| Read, M | 2 |
| Birowo, P | 1 |
| Uckert, S | 2 |
| Kedia, GT | 1 |
| Sonnenberg, JE | 1 |
| Sandner, P | 1 |
| Thon, WF | 1 |
| Scheller, F | 1 |
| Rahardjo, D | 1 |
| Kuczyk, MA | 1 |
| Usta, C | 2 |
| Sadan, G | 2 |
| Tuncel, B | 1 |
| Lau, LC | 1 |
| Adaikan, PG | 1 |
| Oger, S | 1 |
| Behr-Roussel, D | 1 |
| Gorny, D | 1 |
| Denys, P | 1 |
| Lebret, T | 1 |
| Alexandre, L | 1 |
| Giuliano, F | 1 |
| Santos-Silva, AJ | 1 |
| Cairrão, E | 1 |
| Morgado, M | 1 |
| Alvarez, E | 1 |
| Verde, I | 1 |
| Hu, A | 1 |
| Nino, G | 1 |
| Grunstein, JS | 1 |
| Fatma, S | 1 |
| Grunstein, MM | 1 |
| Fujita, H | 1 |
| Usui, H | 1 |
| Kurahashi, K | 1 |
| Yoshikawa, M | 1 |
| Rabe, KF | 2 |
| Tenor, H | 2 |
| Dent, G | 2 |
| Schudt, C | 2 |
| Nakashima, M | 1 |
| Magnussen, H | 2 |
| Barbier, AJ | 1 |
| Lefebvre, RA | 1 |
| Yu, SM | 1 |
| Kuo, SC | 1 |
| Liebig, S | 1 |
| Foda, HD | 1 |
| Said, SI | 1 |
| Truss, MC | 1 |
| Stief, CG | 2 |
| Schulz-Knappe, P | 2 |
| Hess, R | 1 |
| Forssmann, WG | 2 |
| Jonas, U | 2 |
| Taher, A | 1 |
| Meyer, M | 1 |
| Truss, M | 1 |
| Ellis, JL | 2 |
| Conanan, ND | 1 |
| Fernandes, LB | 1 |
| Undem, BJ | 1 |
| Turner, NC | 1 |
| Lamb, J | 1 |
| Worby, A | 1 |
| Murray, KJ | 1 |
| Souness, JE | 1 |
| Villamil, ME | 1 |
| Scott, LC | 1 |
| Tomkinson, A | 2 |
| Giembycz, MA | 1 |
| Raeburn, D | 2 |
| Ivorra, MD | 1 |
| Lugnier, C | 2 |
| Catret, M | 1 |
| Anselmi, E | 1 |
| Cortes, D | 1 |
| D'Ocon, P | 1 |
| Karlsson, JA | 1 |
| Holbrook, M | 1 |
| Gozzard, N | 1 |
| James, T | 1 |
| Higgs, G | 1 |
| Hughes, B | 1 |
| Planquois, JM | 1 |
| Ruffin-Morin, Y | 1 |
| Lagente, V | 1 |
| Payne, AN | 1 |
| Dahl, SG | 1 |
| Cortijo, J | 1 |
| Villagrasa, V | 1 |
| Navarrete, C | 1 |
| Sanz, C | 1 |
| Berto, L | 1 |
| Michel, A | 1 |
| Bonnet, PA | 1 |
| Morcillo, EJ | 1 |
| Perez-Vallina, JR | 1 |
| Revuelta, MP | 1 |
| Cantabrana, B | 1 |
| Hidalgo, A | 1 |
| Eckly-Michel, A | 1 |
| Martin, V | 1 |
| Thirstrup, S | 1 |
| Dahl, R | 1 |
| Nielsen-Kudsk, F | 1 |
| Wright, KF | 1 |
| Turner, CR | 1 |
| Jayasinghe-Beck, R | 1 |
| Cohen, VL | 1 |
| Cheng, JB | 1 |
| Watson, JW | 1 |
| Méhats, C | 1 |
| Tanguy, G | 1 |
| Paris, B | 1 |
| Robert, B | 1 |
| Pernin, N | 1 |
| Ferré, F | 1 |
| Leroy, MJ | 1 |
| Devillier, P | 1 |
| Corompt, E | 1 |
| Bréant, D | 1 |
| Caron, F | 1 |
| Bessard, G | 1 |
| Jones, OM | 1 |
| Brading, AF | 1 |
| McC Mortensen, NJ | 1 |
| Absood, A | 1 |
| Chen, D | 1 |
| Wang, ZY | 1 |
| Håkanson, R | 1 |
| Lindgren, S | 1 |
| Rascón, A | 1 |
| Andersson, KE | 1 |
| Manganiello, V | 1 |
| Degerman, E | 1 |
| Hall, IP | 1 |
| Hill, SJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Medication Facilitated Ureteral Access Sheath Deployment During Ureteroscopy and Endoscopic-Guided Percutaneous Nephrolithotomy: A Randomized Double-Blind Placebo Controlled Trial of Tadalafil, Tamsulosin and Combination[NCT03229889] | Phase 4 | 220 participants (Anticipated) | Interventional | 2017-06-07 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
45 other studies available for rolipram and Muscle Relaxation
| Article | Year |
|---|---|
New bronchodilators. 3. Imidazo[4,5-c][1,8]naphthyridin-4(5H)-ones.
Topics: Animals; Bronchodilator Agents; Drug Interactions; Guinea Pigs; Imidazoles; Male; Mice; Muscle Relax | 1992 |
Selective inhibitors of cyclic AMP-specific phosphodiesterase: heterocycle-condensed purines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Animals; Cyclic Nucleotide Phosphodiester | 1997 |
4-(3-Chloro-4-methoxybenzyl)aminophthalazines: synthesis and inhibitory activity toward phosphodiesterase 5.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antihypertensive Agents; Biological Availability; Bloo | 2000 |
Improvement of therapeutic index of phosphodiesterase type IV inhibitors as anti-Asthmatics.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Asthmatic Agents; Binding Sites; Brain; Bronchoal | 2003 |
Phosphodiesterase type 4 inhibition enhances nitric oxide- and hydrogen sulfide-mediated bladder neck inhibitory neurotransmission.
Topics: Adult; Aged; Animals; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Hydrogen Sulfide; Male; | 2018 |
Estradiol mediates relaxation of porcine lower esophageal sphincter.
Topics: Animals; Cyclic AMP; Cyclic GMP; Esophageal Sphincter, Lower; Estradiol; Muscle Relaxation; Nitric O | 2018 |
Effect of co-administration of two different phosphodiesterase inhibitors and a β
Topics: Adrenergic beta-3 Receptor Agonists; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; | 2018 |
BK channel-mediated relaxation of urinary bladder smooth muscle: a novel paradigm for phosphodiesterase type 4 regulation of bladder function.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium; Calcium Signaling; Cell Polarity; | 2014 |
Powerful relaxation of phosphodiesterase type 4 inhibitor rolipram in the pig and human bladder neck.
Topics: Adult; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; | 2014 |
Evidence that a protein kinase A substrate, small heat-shock protein 20, modulates myometrial relaxation in human pregnancy.
Topics: Actins; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide | 2008 |
Evidence that corticotropin-releasing hormone modulates myometrial contractility during human pregnancy.
Topics: Adult; Albuterol; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Synergism; | 2009 |
Exposure of human seminal vesicle tissue to phosphodiesterase (PDE) inhibitors antagonizes the contraction induced by norepinephrine and increases production of cyclic nucleotides.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aged; Colforsin; Cyclic AMP; Cyclic GMP; Drug Evalua | 2010 |
The effect of the indomethacin on phosphodiesterase inhibitors mediated responses in isolated trachea preparations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Guinea Pigs; Histamine; In Vitro Techniques; Indom | 2004 |
Effect of sildenafil and rolipram on adrenergic responses in isolated human and monkey corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Antagonists; Animals; Erectile Dysfunction; Hu | 2007 |
Relaxation of phasic contractile activity of human detrusor strips by cyclic nucleotide phosphodiesterase type 4 inhibition.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Rel | 2007 |
PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide | 2008 |
Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Butadienes; Cells, Cultured; Colforsin; Cyclic | 2008 |
Isolation and characterization of ovokinin, a bradykinin B1 agonist peptide derived from ovalbumin.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Bradykinin; Dinoprost; Dogs; Dose-Respons | 1995 |
Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Antihypertensive Agents; Carbachol; Colforsin; Cytosol; Di | 1994 |
Relaxant influence of phosphodiesterase inhibitors in the cat gastric fundus.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Female; Ga | 1995 |
Vasorelaxant effect of isoliquiritigenin, a novel soluble guanylate cyclase activator, in rat aorta.
Topics: Aldehyde Reductase; Animals; Aorta; Chalcone; Chalcones; Cyclic AMP; Cyclic GMP; Dose-Response Relat | 1995 |
Phosphodiesterase isozymes modulating inherent tone in human airways: identification and characterization.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adult; Aged; Bucladesine; C | 1993 |
Nitric oxide and VIP as co-transmitters of neurogenic relaxation of human airways.
Topics: Autonomic Nervous System; Bronchi; Humans; Muscle Relaxation; Nitric Oxide; Phosphodiesterase Inhibi | 1995 |
Porcine detrusor cyclic nucleotide phosphodiesterase isoenzymes: characterization and functional effects of various phosphodiesterase inhibitors in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calmodulin; Carba | 1995 |
Characterization of cyclic nucleotide phosphodiesterase isoenzymes in the human ureter and their functional role in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calmodulin; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic | 1994 |
Modulation of relaxant responses evoked by a nitric oxide donor and by nonadrenergic, noncholinergic stimulation by isozyme-selective phosphodiesterase inhibitors in guinea pig trachea.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Atropine; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Ph | 1995 |
Potentiation of nonadrenergic noncholinergic relaxation of human isolated bronchus by selective inhibitors of phosphodiesterase isozymes.
Topics: Atropine; Bronchi; Colforsin; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Indometh | 1994 |
Relaxation of guinea-pig trachea by cyclic AMP phosphodiesterase inhibitors and their enhancement by sodium nitroprusside.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Dr | 1994 |
Possible role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane generation and airways smooth muscle tone.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic AMP; Eosinophils; Guinea Pigs; In Vitro Techniq | 1994 |
Investigations of the dual contractile/relaxant properties showed by antioquine in rat aorta.
Topics: Alkaloids; Animals; Aorta, Thoracic; Benzylisoquinolines; Caffeine; Calcium; Calcium Channel Blocker | 1993 |
Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes.
Topics: Albuterol; Animals; Bronchi; Cattle; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In V | 1993 |
Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor.
Topics: Analysis of Variance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol | 1996 |
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug S | 1996 |
Effects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: comparison with rolipram, SKF94120 and levcromakalim.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Anti-Inflammatory Agents, | 1996 |
Effect of Rp diastereoisomer of adenosine 3',5' cyclic-monophosphothioate on the cAMP-dependent relaxation of smooth muscle.
Topics: Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Inhibitors; Female; Histamine; Muscle Rela | 1997 |
Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Aorta; Calcium; Cardiotonic Agents; Cycli | 1997 |
Interaction between prostaglandins and selective phosphodiesterase inhibitors in isolated guinea-pig trachea in vitro.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Drug Interactions; Female; Guanidines; | 1997 |
Differential in vivo and in vitro bronchorelaxant activities of CP-80,633, a selective phosphodiesterase 4 inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Antagonists; Animals; Bronchodilator Agents; Ca | 1997 |
Comparison of the effects of selective III, IV and nonselective phosphodiesterase inhibitors on isolated tracheal preparations in streptozotocin-diabetic rats.
Topics: Amrinone; Animals; Carbachol; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dose-Response Rel | 2000 |
Pregnancy induces a modulation of the cAMP phosphodiesterase 4-conformers ratio in human myometrium: consequences for the utero-relaxant effect of PDE4-selective inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Benzamides; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, T | 2000 |
Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Apamin; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Dose-Response | 2001 |
Phosphodiesterase inhibitors cause relaxation of the internal anal sphincter in vitro.
Topics: Adenine; Aged; Aged, 80 and over; Anal Canal; Dipyridamole; Dose-Response Relationship, Drug; Female | 2002 |
Vascular effects of pituitary adenylate cyclase activating peptide: a comparison with vasoactive intestinal peptide.
Topics: Animals; Arteries; Blood Pressure; Cyclic AMP; In Vitro Techniques; Male; Muscle Relaxation; Muscle, | 1992 |
Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Aorta; Cyclic AMP; Cyclic GMP; Drug Interaction | 1991 |
Effects of isozyme selective phosphodiesterase inhibitors on bovine tracheal smooth muscle tone.
Topics: Animals; Bronchodilator Agents; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Isoen | 1992 |