rolipram has been researched along with Muscle Contraction in 47 studies
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to evaluate the effects of selective PDE4 (rolipram, ROL) and PDE7 inhibitors (BRL50481, BRL) on citric acid-induced cough, in vivo and in vitro airway smooth muscle reactivity in both healthy and ovalbumin sensitized guinea pigs." | 7.79 | Effects of selective inhibition of PDE4 and PDE7 on airway reactivity and cough in healthy and ovalbumin-sensitized guinea pigs. ( Christensen, I; Joskova, M; Mokra, D; Mokry, J; Nosalova, G, 2013) |
| " The aim of the present study was to evaluate the effects of selective PDE4 (rolipram, ROL) and PDE7 inhibitors (BRL50481, BRL) on citric acid-induced cough, in vivo and in vitro airway smooth muscle reactivity in both healthy and ovalbumin sensitized guinea pigs." | 3.79 | Effects of selective inhibition of PDE4 and PDE7 on airway reactivity and cough in healthy and ovalbumin-sensitized guinea pigs. ( Christensen, I; Joskova, M; Mokra, D; Mokry, J; Nosalova, G, 2013) |
| "Chronic exposure of human isolated bronchi to beta2-adrenergic agonists, especially fenoterol, potentiates smooth muscle contraction in response to endothelin-1 (ET-1), a peptide implicated in chronic inflammatory airway diseases." | 3.73 | Phosphodiesterase 4 inhibitors modulate beta2-adrenoceptor agonist-induced human airway hyperresponsiveness. ( Advenier, C; Devillier, P; Fagon, JY; Faisy, C; Guerot, E; Naline, E; Risse, PA, 2006) |
| " We have investigated the effects of RP 73401, a novel, potent and highly selective cyclic nucleotide phosphodiesterase (PDE) type IV inhibitor, in guinea-pig and rat models of bronchoconstriction and allergic inflammation." | 3.69 | Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor. ( Battram, CH; Jordan, R; Lewis, SA; Raeburn, D; Sharma, S; Souness, JE; Tomkinson, A; Underwood, SL; Webber, SE; Woodman, VR, 1994) |
| "New therapeutic targets in benign prostatic hyperplasia (BPH) mainly concern phosphodiesterase type 5 (PDE-5) inhibitors." | 1.34 | [Recent progress in basic research concerning the management of benign prostatic hyperplasia]. ( Cornu, JN; Rouprêt, M, 2007) |
| "Pre-treatment with motapizone, RP73401, rolipram or the methylxanthine adenosine receptor antagonist, 8-phenyltheophylline, did not significantly decrease responses to either allergen or LTC(4)." | 1.31 | The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways. ( Branscheid, D; Dent, G; Magnussen, H; Rabe, KF; Rühlmann, E; Schmidt, DT; Watson, N, 2000) |
| "The isoproterenol effects were blocked by the antagonist propranolol." | 1.31 | Systemic and topical drug administration in the pig ureter: effect of phosphodiesterase inhibitors alpha1, beta and beta2-adrenergic receptor agonists and antagonists on the frequency and amplitude of ureteral contractions. ( Abel, D; Danuser, H; Mettler, D; Scholtysik, G; Studer, UE; Walter, B; Weiss, R, 2001) |
| "Rolipram was approximately 2600 fold less potent than RP 73401 against pig aortic smooth muscle PDE IV (IC50 = 3162 nM) and about 250 times less potent against eosinophil PDE IV (IC50 = 186 nM)." | 1.29 | Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram. ( Ashton, MJ; Foster, M; Karlsson, JA; Maslen, C; Palfreyman, MN; Raeburn, D; Souness, JE; Webber, S, 1995) |
| "Rolipram was more potent than siguazodan and, in terms of efficacy, it was less active." | 1.29 | Effects of rolipram and siguazodan on the human isolated bronchus and their interaction with isoprenaline and sodium nitroprusside. ( Advenier, C; Karlsson, JA; Naline, E; Qian, Y; Raeburn, D, 1993) |
| "Siguazodan was 100 fold more active than rolipram in pig tissues indicating the type III isoenzyme may be of greater functional significance in this tissue." | 1.29 | Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes. ( Karlsson, JA; Raeburn, D; Tomkinson, A, 1993) |
| ") did not bronchodilate but caused a parallel 7 fold rightward shift in the histamine dose-response curve." | 1.29 | Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor. ( Gozzard, N; Higgs, G; Holbrook, M; Hughes, B; James, T, 1996) |
| "When OPC 3911 or milrinone was combined with rolipram more than additive effects on aortic relaxation and cAMP content were obtained." | 1.28 | Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta. ( Andersson, KE; Degerman, E; Lindgren, S; Manganiello, V; Rascón, A, 1991) |
| "Rolipram was the most potent compound in the three species." | 1.27 | Species differences in behavioural effects of rolipram and other adenosine cyclic 3H, 5H-monophosphate phosphodiesterase inhibitors. ( Wachtel, H, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.51) | 18.7374 |
| 1990's | 19 (40.43) | 18.2507 |
| 2000's | 16 (34.04) | 29.6817 |
| 2010's | 8 (17.02) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Linhares, BL | 1 |
| Nascimento, NRF | 1 |
| Gonzaga-Silva, LF | 1 |
| Santos, CF | 1 |
| Moraes, MO | 1 |
| Marinho, LB | 1 |
| Silva, APG | 1 |
| Fonteles, MC | 1 |
| Reges, R | 1 |
| Ribeiro, ASF | 1 |
| Fernandes, VS | 1 |
| Martínez-Sáenz, A | 1 |
| Martínez, P | 1 |
| Barahona, MV | 2 |
| Orensanz, LM | 2 |
| Blaha, I | 1 |
| Serrano-Margüello, D | 1 |
| Bustamante, S | 1 |
| Carballido, J | 1 |
| García-Sacristán, A | 3 |
| Prieto, D | 3 |
| Hernández, M | 3 |
| Fernández-Martínez, E | 1 |
| Ponce-Monter, H | 1 |
| Soria-Jasso, LE | 1 |
| Ortiz, MI | 1 |
| Arias-Montaño, JA | 1 |
| Barragán-Ramírez, G | 1 |
| Mayén-García, C | 1 |
| Galindo-Tovar, A | 1 |
| Vargas, ML | 1 |
| Escudero, E | 1 |
| Kaumann, AJ | 1 |
| Kaneda, T | 1 |
| Kubota, T | 1 |
| Fujimoto, K | 1 |
| Urakawa, N | 1 |
| Nakajyo, S | 1 |
| Shimizu, K | 1 |
| Shah, AJ | 1 |
| Gilani, AH | 1 |
| Duarte, T | 1 |
| Menezes-Rodrigues, FS | 1 |
| Godinho, RO | 1 |
| Mokry, J | 1 |
| Joskova, M | 1 |
| Mokra, D | 1 |
| Christensen, I | 1 |
| Nosalova, G | 1 |
| Kedia, GT | 1 |
| Ückert, S | 3 |
| Polat, H | 1 |
| Merseburger, AS | 1 |
| Kuczyk, MA | 1 |
| Méhats, C | 1 |
| Jin, SL | 1 |
| Wahlstrom, J | 1 |
| Law, E | 1 |
| Umetsu, DT | 1 |
| Conti, M | 1 |
| Usta, C | 2 |
| Sadan, G | 2 |
| Tuncel, B | 1 |
| Faisy, C | 1 |
| Risse, PA | 1 |
| Naline, E | 2 |
| Guerot, E | 1 |
| Fagon, JY | 1 |
| Devillier, P | 2 |
| Advenier, C | 2 |
| Recio, P | 1 |
| Benedito, S | 1 |
| Martínez, AC | 2 |
| Rivera, L | 1 |
| Lau, LC | 1 |
| Adaikan, PG | 1 |
| Cornu, JN | 1 |
| Rouprêt, M | 1 |
| Santos-Silva, AJ | 1 |
| Cairrão, E | 1 |
| Morgado, M | 1 |
| Alvarez, E | 1 |
| Verde, I | 1 |
| Büyüknacar, HS | 1 |
| Kumcu, EK | 1 |
| Göçmen, C | 1 |
| Onder, S | 1 |
| Hu, A | 1 |
| Nino, G | 1 |
| Grunstein, JS | 1 |
| Fatma, S | 1 |
| Grunstein, MM | 1 |
| Sánchez, A | 1 |
| Villalba, N | 1 |
| Gustafsson, LE | 2 |
| Wachtel, H | 1 |
| Gustafsson, L | 1 |
| Fredholm, BB | 1 |
| Hedqvist, P | 2 |
| Wright, IK | 1 |
| Kendall, DA | 1 |
| Wilson, VG | 1 |
| Rabe, KF | 2 |
| Tenor, H | 1 |
| Dent, G | 2 |
| Schudt, C | 1 |
| Nakashima, M | 1 |
| Magnussen, H | 2 |
| Grous, M | 1 |
| Barnette, M | 1 |
| Souness, JE | 2 |
| Maslen, C | 1 |
| Webber, S | 1 |
| Foster, M | 1 |
| Raeburn, D | 4 |
| Palfreyman, MN | 1 |
| Ashton, MJ | 1 |
| Karlsson, JA | 3 |
| Truss, MC | 1 |
| Stief, CG | 2 |
| Schulz-Knappe, P | 2 |
| Hess, R | 1 |
| Forssmann, WG | 2 |
| Jonas, U | 2 |
| Eckly, AE | 1 |
| Lugnier, C | 2 |
| Underwood, SL | 1 |
| Lewis, SA | 1 |
| Woodman, VR | 1 |
| Battram, CH | 1 |
| Tomkinson, A | 2 |
| Sharma, S | 1 |
| Jordan, R | 1 |
| Webber, SE | 1 |
| Ivorra, MD | 1 |
| Catret, M | 1 |
| Anselmi, E | 1 |
| Cortes, D | 1 |
| D'Ocon, P | 1 |
| Qian, Y | 1 |
| Underwood, DC | 1 |
| Osborn, RR | 1 |
| Novak, LB | 1 |
| Matthews, JK | 1 |
| Newsholme, SJ | 1 |
| Undem, BJ | 1 |
| Hand, JM | 1 |
| Torphy, TJ | 1 |
| Taher, A | 1 |
| Truss, M | 1 |
| Becker, AJ | 1 |
| Meyer, M | 1 |
| Holbrook, M | 1 |
| Gozzard, N | 1 |
| James, T | 1 |
| Higgs, G | 1 |
| Hughes, B | 1 |
| Planquois, JM | 1 |
| Ruffin-Morin, Y | 1 |
| Lagente, V | 1 |
| Payne, AN | 1 |
| Dahl, SG | 1 |
| Longhurst, PA | 1 |
| Briscoe, JA | 1 |
| Rosenberg, DJ | 1 |
| Leggett, RE | 1 |
| Thirstrup, S | 1 |
| Dahl, R | 1 |
| Nielsen-Kudsk, F | 1 |
| Manabe, H | 1 |
| Akuta, K | 1 |
| Okamura, K | 1 |
| Ohmori, K | 1 |
| Schmidt, DT | 1 |
| Watson, N | 1 |
| Rühlmann, E | 1 |
| Branscheid, D | 1 |
| Lis-Balchin, M | 1 |
| Hart, S | 1 |
| Simpson, E | 1 |
| Danuser, H | 1 |
| Weiss, R | 1 |
| Abel, D | 1 |
| Walter, B | 1 |
| Scholtysik, G | 1 |
| Mettler, D | 1 |
| Studer, UE | 1 |
| Corompt, E | 1 |
| Bréant, D | 1 |
| Caron, F | 1 |
| Bessard, G | 1 |
| Lindgren, S | 1 |
| Rascón, A | 1 |
| Andersson, KE | 1 |
| Manganiello, V | 1 |
| Degerman, E | 1 |
| Rapoport, RM | 1 |
| Wiklund, NP | 1 |
| Lundin, J | 1 |
47 other studies available for rolipram and Muscle Contraction
| Article | Year |
|---|---|
Effect of co-administration of two different phosphodiesterase inhibitors and a β
Topics: Adrenergic beta-3 Receptor Agonists; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; | 2018 |
Powerful relaxation of phosphodiesterase type 4 inhibitor rolipram in the pig and human bladder neck.
Topics: Adult; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; | 2014 |
Inhibition of Uterine Contractility by Thalidomide Analogs via Phosphodiesterase-4 Inhibition and Calcium Entry Blockade.
Topics: Adolescent; Adult; Calcium; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP; Dose-Response Rel | 2016 |
Ontogenic changes of the control by phosphodiesterase-3 and -4 of 5-HT responses in porcine heart and relevance to human atrial 5-HT(4) receptors.
Topics: Age Factors; Animals; Animals, Newborn; Arrhythmia, Sinus; Atrial Function; Calcium Channels, L-Type | 2009 |
Effects of rolipram on U46619-induced contraction and cyclic nucleotide content in the porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Caffeine; Calciu | 2010 |
Bronchodilatory effect of Acorus calamus (Linn.) is mediated through multiple pathways.
Topics: Acorus; Animals; Atropine; Bronchodilator Agents; Calcium Channel Blockers; Carbachol; Female; Guine | 2010 |
Contribution of the extracellular cAMP-adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle.
Topics: Adenosine; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Clenbuterol; Colf | 2012 |
Effects of selective inhibition of PDE4 and PDE7 on airway reactivity and cough in healthy and ovalbumin-sensitized guinea pigs.
Topics: Acetylcholine; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Citric Ac | 2013 |
Evaluating the significance of cyclic adenosine monophosphate-mediated signaling in human prostate: a functional and biochemical study.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aged; Benzamides; Colforsin; Cyclic AMP; Humans; In | 2012 |
PDE4D plays a critical role in the control of airway smooth muscle contraction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arginine Vasopressin; Bronchoconstrictor Agents; Carba | 2003 |
The effect of the indomethacin on phosphodiesterase inhibitors mediated responses in isolated trachea preparations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Guinea Pigs; Histamine; In Vitro Techniques; Indom | 2004 |
Phosphodiesterase 4 inhibitors modulate beta2-adrenoceptor agonist-induced human airway hyperresponsiveness.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; | 2006 |
Neuronal and smooth muscle receptors involved in the PACAP- and VIP-induced relaxations of the pig urinary bladder neck.
Topics: Adenylyl Cyclases; Animals; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, V | 2006 |
Effect of sildenafil and rolipram on adrenergic responses in isolated human and monkey corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenergic alpha-Antagonists; Animals; Erectile Dysfunction; Hu | 2007 |
[Recent progress in basic research concerning the management of benign prostatic hyperplasia].
Topics: Colforsin; Humans; Male; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Piperazines; Prostatic | 2007 |
PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide | 2008 |
Effect of phosphodiesterase type 4 inhibitor rolipram on cyclophosphamide-induced cystitis in rats.
Topics: Anesthesia; Animals; Antineoplastic Agents, Alkylating; Calcium Channel Blockers; Cyclophosphamide; | 2008 |
Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Butadienes; Cells, Cultured; Colforsin; Cyclic | 2008 |
Mechanisms of the relaxant effect of vardenafil in rat penile arteries.
Topics: Animals; Arteries; Calcium Channel Blockers; Cyclic GMP; Dose-Response Relationship, Drug; Endotheli | 2008 |
Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Atropine; Choline; Electric Stimulation; Guine | 1984 |
Species differences in behavioural effects of rolipram and other adenosine cyclic 3H, 5H-monophosphate phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Behavior, Anim | 1983 |
Theophylline interferes with the modulatory role of endogenous adenosine on cholinergic neurotransmission in guinea pig ileum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cholin | 1981 |
Alpha 2-adrenoceptor mediated inhibition of forskolin-stimulated cyclic AMP accumulation in isolated porcine palmar lateral veins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonist | 1995 |
Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Antihypertensive Agents; Carbachol; Colforsin; Cytosol; Di | 1994 |
Prevention by phosphodiesterase inhibitors of antigen-induced contraction of guinea-pig colonic smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterase | 1994 |
Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Base Sequence; Benzamides; Blood Proteins; Catt | 1995 |
Porcine detrusor cyclic nucleotide phosphodiesterase isoenzymes: characterization and functional effects of various phosphodiesterase inhibitors in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calmodulin; Carba | 1995 |
Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta, Thoracic; Cardiotonic Agents; Cyclic AMP; Cycli | 1994 |
Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor.
Topics: Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bronchial Hyperreactivity; | 1994 |
Investigations of the dual contractile/relaxant properties showed by antioquine in rat aorta.
Topics: Alkaloids; Animals; Aorta, Thoracic; Benzylisoquinolines; Caffeine; Calcium; Calcium Channel Blocker | 1993 |
Effects of rolipram and siguazodan on the human isolated bronchus and their interaction with isoprenaline and sodium nitroprusside.
Topics: Albuterol; Bronchi; Guanidines; Humans; In Vitro Techniques; Isoproterenol; Muscle Contraction; Musc | 1993 |
Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram.
Topics: Anesthesia; Animals; Antigens; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Consciousness; Cyc | 1993 |
Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing beta-adrenoceptor subtypes.
Topics: Albuterol; Animals; Bronchi; Cattle; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In V | 1993 |
Phosphodiesterase isoenzymes in human ureteral smooth muscle: identification, characterization, and functional effects of various phosphodiesterase inhibitors in vitro.
Topics: Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydr | 1995 |
Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor.
Topics: Analysis of Variance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol | 1996 |
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug S | 1996 |
The role of cyclic nucleotides in guinea-pig bladder contractility.
Topics: Animals; Carbachol; Colforsin; Cyclic AMP; Electric Stimulation; Female; Guinea Pigs; In Vitro Techn | 1997 |
Interaction between prostaglandins and selective phosphodiesterase inhibitors in isolated guinea-pig trachea in vitro.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Drug Interactions; Female; Guanidines; | 1997 |
KF19514, a phosphodieterase 4 and 1 inhibitor, inhibits PAF-induced lung inflammatory responses by inhaled administration in guinea pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; As | 1997 |
Comparison of the effects of selective III, IV and nonselective phosphodiesterase inhibitors on isolated tracheal preparations in streptozotocin-diabetic rats.
Topics: Amrinone; Animals; Carbachol; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dose-Response Rel | 2000 |
The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Antigens, Dermatophagoides; Benzam | 2000 |
Buchu (Agathosma betulina and A. crenulata, Rutaceae) essential oils: their pharmacological action on guinea-pig ileum and antimicrobial activity on microorganisms.
Topics: Animals; Calcium Channels; Culture Techniques; Cyclic AMP; Dose-Response Relationship, Drug; Enteroc | 2001 |
Systemic and topical drug administration in the pig ureter: effect of phosphodiesterase inhibitors alpha1, beta and beta2-adrenergic receptor agonists and antagonists on the frequency and amplitude of ureteral contractions.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Ag | 2001 |
Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Apamin; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Dose-Response | 2001 |
Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Aorta; Cyclic AMP; Cyclic GMP; Drug Interaction | 1991 |
Inhibitory effects of cyclic AMP-elevating agents on norepinephrine-induced phosphatidylinositide hydrolysis and contraction in rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Buclades | 1991 |
Characterization of pre- and post-junctional adenosine receptors in guinea-pig ileum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cholinergic Fibers; Colfor | 1985 |