rolipram has been researched along with Irritable Bowel Syndrome in 2 studies
Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For roflumilast, ID(50)s were 24." | 1.35 | Inhibition of phosphodiesterase type 4 decreases stress-induced defecation in rats and mice. ( Barone, FC; Barton, ME; Kikkawa, H; Kinoshita, M; Kuratani, K; Legos, JJ; Shimamura, M; White, RF, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, F | 1 |
| Ren, H | 1 |
| Tan, W | 1 |
| Wang, Y | 1 |
| Luo, H | 1 |
| Barone, FC | 1 |
| Barton, ME | 1 |
| White, RF | 1 |
| Legos, JJ | 1 |
| Kikkawa, H | 1 |
| Shimamura, M | 1 |
| Kuratani, K | 1 |
| Kinoshita, M | 1 |
2 other studies available for rolipram and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Effect of phosphodiesterase-4 inhibitor rolipram on colonic hypermotility in water avoidance stress rat model.
Topics: Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Inhibitors; Irritable Bowe | 2022 |
Inhibition of phosphodiesterase type 4 decreases stress-induced defecation in rats and mice.
Topics: Aminopyridines; Animals; Antidiarrheals; Benzamides; Cold Temperature; Cyclopropanes; Defecation; Ga | 2008 |