Page last updated: 2024-11-04

rolipram and Heart Failure

rolipram has been researched along with Heart Failure in 5 studies

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"The β-blockers carvedilol and metoprolol provide important therapeutic strategies for heart failure treatment."3.80Carvedilol induces greater control of β2- than β 1-adrenoceptor-mediated inotropic and lusitropic effects by PDE3, while PDE4 has no effect in human failing myocardium. ( Berk, E; Christ, T; Engel, A; Galindo-Tovar, A; Gillette, KT; Kaumann, AJ; Molenaar, P; Ravens, U, 2014)
"Enhanced arginine vasopressin levels are associated with increased mortality during end-stage human heart failure, and cardiac arginine vasopressin type 1A receptor (V1AR) expression becomes increased."3.80β-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling. ( Barr, LA; Carter, RL; Cheung, JY; Coleman, RC; Feldman, AM; Gao, E; Grisanti, LA; Houser, SR; Koch, WJ; Li, X; Makarewich, CA; Myers, VD; Song, J; Tilley, DG; Troupes, CD; Yu, D; Zhu, W, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nomoto, Y1
Takai, H1
Ohno, T1
Nagashima, K1
Yao, K1
Yamada, K1
Kubo, K1
Ichimura, M1
Mihara, A1
Kase, H1
Orstavik, O1
Ata, SH1
Riise, J1
Dahl, CP1
Andersen, GØ1
Levy, FO2
Skomedal, T2
Osnes, JB2
Qvigstad, E1
Molenaar, P1
Christ, T1
Berk, E1
Engel, A1
Gillette, KT1
Galindo-Tovar, A1
Ravens, U1
Kaumann, AJ1
Tilley, DG1
Zhu, W1
Myers, VD1
Barr, LA1
Gao, E1
Li, X1
Song, J1
Carter, RL1
Makarewich, CA1
Yu, D1
Troupes, CD1
Grisanti, LA1
Coleman, RC1
Koch, WJ1
Houser, SR1
Cheung, JY1
Feldman, AM1
Hussain, RI1
Aronsen, JM1
Afzal, F1
Sjaastad, I1
Krobert, KA1

Other Studies

5 other studies available for rolipram and Heart Failure

ArticleYear
Studies of cardiotonic agents. 8. Synthesis and biological activities of optically active 6-(4-(benzylamino)-7-quinazolinyl)-4,5-dihydro-5-methyl-3(2H)- pyridazinone (KF15232).
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Animals; Aorta; Calcium; Cardiotonic Agents; Cattle; Dogs; Guinea Pigs; Heart Failure; In Vitro Tech

1996
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart.
    British journal of pharmacology, 2014, Volume: 171, Issue:23

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Heart; Heart Failure; Humans; Hydraz

2014
Carvedilol induces greater control of β2- than β 1-adrenoceptor-mediated inotropic and lusitropic effects by PDE3, while PDE4 has no effect in human failing myocardium.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Cyclic Nucleotide Phosphodiesterases, Ty

2014
β-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling.
    Circulation, 2014, Nov-11, Volume: 130, Issue:20

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium Signaling; Cardiom

2014
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle.
    Journal of molecular and cellular cardiology, 2013, Volume: 56

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Carbachol; Cardiotonic Agents; GTP-Binding Pro

2013