rolipram and Glioma
rolipram has been researched along with Glioma in 7 studies
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the functional significance of type IV phosphodiesterase (PDEIV) in neurons and glia cells [3H]rolipram binding and phosphodiesterase (PDE) activity were examined in cytosol and membrane fractions of neuroblastoma N18TG-2 and glioma C6Bu-1 cells." | 7.69 | [3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1. ( Hasegawa, H; Murayama, T; Nogiri, S; Nomura, Y; Tohda, M, 1994) |
| "Theophylline was equally potent as an inhibitor of PDE in all cell lines, but the non-xanthine, inhibitor rolipram, was more potent against neuroblastoma than glial cell PDE." | 5.27 | Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells. ( Elfman, L; Fredholm, BB; Lindgren, E; Walum, E, 1984) |
| "To clarify the functional significance of type IV phosphodiesterase (PDEIV) in neurons and glia cells [3H]rolipram binding and phosphodiesterase (PDE) activity were examined in cytosol and membrane fractions of neuroblastoma N18TG-2 and glioma C6Bu-1 cells." | 3.69 | [3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1. ( Hasegawa, H; Murayama, T; Nogiri, S; Nomura, Y; Tohda, M, 1994) |
| "We have demonstrated high affinity diazepam binding sites of the Ro5-4864 benzodiazepine receptor subtype on 108CC15 neuroblastoma X glioma hybrid cells." | 3.67 | Benzodiazepines modulate the A2 adenosine binding sites on 108CC15 neuroblastoma X glioma hybrid cells. ( Snell, CR; Snell, PH, 1984) |
| "Theophylline was equally potent as an inhibitor of PDE in all cell lines, but the non-xanthine, inhibitor rolipram, was more potent against neuroblastoma than glial cell PDE." | 1.27 | Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells. ( Elfman, L; Fredholm, BB; Lindgren, E; Walum, E, 1984) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Liu, J | 1 |
| Ye, W | 1 |
| Xu, JP | 1 |
| Wang, HT | 1 |
| Li, XF | 1 |
| Wang, WY | 1 |
| Zhou, ZZ | 1 |
| Ou, M | 1 |
| Cho, HY | 1 |
| Fu, J | 1 |
| Thein, TZ | 1 |
| Wang, W | 1 |
| Swenson, SD | 1 |
| Minea, RO | 1 |
| Stathopoulos, A | 1 |
| Schönthal, AH | 1 |
| Hofman, FM | 1 |
| Tang, L | 1 |
| Chen, TC | 1 |
| Ramezani, S | 1 |
| Vousooghi, N | 1 |
| Ramezani Kapourchali, F | 1 |
| Yousefzadeh-Chabok, S | 1 |
| Reihanian, Z | 1 |
| Alizadeh, AM | 1 |
| Khodayari, S | 1 |
| Khodayari, H | 1 |
| Leemhuis, J | 1 |
| Boutillier, S | 1 |
| Barth, H | 1 |
| Feuerstein, TJ | 1 |
| Brock, C | 1 |
| Nürnberg, B | 1 |
| Aktories, K | 1 |
| Meyer, DK | 1 |
| Elfman, L | 1 |
| Lindgren, E | 1 |
| Walum, E | 1 |
| Fredholm, BB | 1 |
| Snell, CR | 1 |
| Snell, PH | 1 |
| Tohda, M | 1 |
| Murayama, T | 1 |
| Hasegawa, H | 1 |
| Nogiri, S | 1 |
| Nomura, Y | 1 |
Other Studies
7 other studies available for rolipram and Glioma
| Article | Year |
|---|---|
Discovery of novel trimethoxyphenylbenzo[d]oxazoles as dual tubulin/PDE4 inhibitors capable of inducing apoptosis at G2/M phase arrest in glioma and lung cancer cells.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cyclic Nucleotide Phosphodiesterases, Type 4; | 2021 |
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
Topics: Autophagy; Cell Death; Chloroquine; Glioblastoma; Glioma; Humans; Lysosomes; Monoterpenes; Rolipram; | 2023 |
Rolipram optimizes therapeutic effect of bevacizumab by enhancing proapoptotic, antiproliferative signals in a glioblastoma heterotopic model.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevaciz | 2019 |
Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites.
Topics: Amides; Androstadienes; Animals; Brain; Colforsin; Dendrites; Enzyme Inhibitors; Genes, Reporter; Gl | 2004 |
Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Line; Cells, Cultured; Cyclic | 1984 |
Benzodiazepines modulate the A2 adenosine binding sites on 108CC15 neuroblastoma X glioma hybrid cells.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Cells, Cultured; Clonazepam; Cy | 1984 |
[3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imi | 1994 |