Page last updated: 2024-11-04

rolipram and Glioma

rolipram has been researched along with Glioma in 7 studies

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"To clarify the functional significance of type IV phosphodiesterase (PDEIV) in neurons and glia cells [3H]rolipram binding and phosphodiesterase (PDE) activity were examined in cytosol and membrane fractions of neuroblastoma N18TG-2 and glioma C6Bu-1 cells."7.69[3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1. ( Hasegawa, H; Murayama, T; Nogiri, S; Nomura, Y; Tohda, M, 1994)
"Theophylline was equally potent as an inhibitor of PDE in all cell lines, but the non-xanthine, inhibitor rolipram, was more potent against neuroblastoma than glial cell PDE."5.27Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells. ( Elfman, L; Fredholm, BB; Lindgren, E; Walum, E, 1984)
"To clarify the functional significance of type IV phosphodiesterase (PDEIV) in neurons and glia cells [3H]rolipram binding and phosphodiesterase (PDE) activity were examined in cytosol and membrane fractions of neuroblastoma N18TG-2 and glioma C6Bu-1 cells."3.69[3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1. ( Hasegawa, H; Murayama, T; Nogiri, S; Nomura, Y; Tohda, M, 1994)
"We have demonstrated high affinity diazepam binding sites of the Ro5-4864 benzodiazepine receptor subtype on 108CC15 neuroblastoma X glioma hybrid cells."3.67Benzodiazepines modulate the A2 adenosine binding sites on 108CC15 neuroblastoma X glioma hybrid cells. ( Snell, CR; Snell, PH, 1984)
"Theophylline was equally potent as an inhibitor of PDE in all cell lines, but the non-xanthine, inhibitor rolipram, was more potent against neuroblastoma than glial cell PDE."1.27Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells. ( Elfman, L; Fredholm, BB; Lindgren, E; Walum, E, 1984)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Liu, J1
Ye, W1
Xu, JP1
Wang, HT1
Li, XF1
Wang, WY1
Zhou, ZZ1
Ou, M1
Cho, HY1
Fu, J1
Thein, TZ1
Wang, W1
Swenson, SD1
Minea, RO1
Stathopoulos, A1
Schönthal, AH1
Hofman, FM1
Tang, L1
Chen, TC1
Ramezani, S1
Vousooghi, N1
Ramezani Kapourchali, F1
Yousefzadeh-Chabok, S1
Reihanian, Z1
Alizadeh, AM1
Khodayari, S1
Khodayari, H1
Leemhuis, J1
Boutillier, S1
Barth, H1
Feuerstein, TJ1
Brock, C1
Nürnberg, B1
Aktories, K1
Meyer, DK1
Elfman, L1
Lindgren, E1
Walum, E1
Fredholm, BB1
Snell, CR1
Snell, PH1
Tohda, M1
Murayama, T1
Hasegawa, H1
Nogiri, S1
Nomura, Y1

Other Studies

7 other studies available for rolipram and Glioma

ArticleYear
Discovery of novel trimethoxyphenylbenzo[d]oxazoles as dual tubulin/PDE4 inhibitors capable of inducing apoptosis at G2/M phase arrest in glioma and lung cancer cells.
    European journal of medicinal chemistry, 2021, Nov-15, Volume: 224

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cyclic Nucleotide Phosphodiesterases, Type 4;

2021
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
    Autophagy, 2023, Volume: 19, Issue:12

    Topics: Autophagy; Cell Death; Chloroquine; Glioblastoma; Glioma; Humans; Lysosomes; Monoterpenes; Rolipram;

2023
Rolipram optimizes therapeutic effect of bevacizumab by enhancing proapoptotic, antiproliferative signals in a glioblastoma heterotopic model.
    Life sciences, 2019, Dec-15, Volume: 239

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevaciz

2019
Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites.
    The Journal of biological chemistry, 2004, Jan-02, Volume: 279, Issue:1

    Topics: Amides; Androstadienes; Animals; Brain; Colforsin; Dendrites; Enzyme Inhibitors; Genes, Reporter; Gl

2004
Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:4

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Line; Cells, Cultured; Cyclic

1984
Benzodiazepines modulate the A2 adenosine binding sites on 108CC15 neuroblastoma X glioma hybrid cells.
    British journal of pharmacology, 1984, Volume: 83, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Cells, Cultured; Clonazepam; Cy

1984
[3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1.
    Neuroscience letters, 1994, Jul-04, Volume: 175, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imi

1994