rolipram has been researched along with Disease, Pulmonary in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using a rat model of lipopolysaccharide (LPS)-induced pulmonary inflammation, the antiinflammatory activity of SB 207499 was evaluated and compared to that of the prototypic type-4 phosphodiesterase (PDE4) inhibitor, rolipram." | 3.71 | Comparison of PDE 4 inhibitors, rolipram and SB 207499 (ariflo), in a rat model of pulmonary neutrophilia. ( Chapman, R; Fine, J; Jones, H; Kreutner, W; Kung, TT; Minnicozzi, M; Spond, J, 2001) |
| " Concerns regarding its long-term use particularly in young children has provided an impetus for discovering novel anti-inflammatory molecules with high tolerability and clinical efficacy." | 2.42 | The potential of PDE4 inhibitors in respiratory disease. ( Spina, D, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weishaar, RE | 1 |
| Cain, MH | 1 |
| Bristol, JA | 1 |
| Sharma, R | 1 |
| Kaundal, RK | 1 |
| Sharma, SS | 1 |
| Bopp, T | 1 |
| Dehzad, N | 1 |
| Reuter, S | 1 |
| Klein, M | 1 |
| Ullrich, N | 1 |
| Stassen, M | 1 |
| Schild, H | 1 |
| Buhl, R | 1 |
| Schmitt, E | 1 |
| Taube, C | 1 |
| Spina, D | 1 |
| Parker, JC | 1 |
| Spond, J | 1 |
| Chapman, R | 1 |
| Fine, J | 1 |
| Jones, H | 1 |
| Kreutner, W | 1 |
| Kung, TT | 1 |
| Minnicozzi, M | 1 |
2 reviews available for rolipram and Disease, Pulmonary
| Article | Year |
|---|---|
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; | 1985 |
The potential of PDE4 inhibitors in respiratory disease.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Anti-Inflammatory Agents; Bronchodilator Agents; Clinical Trial | 2004 |
4 other studies available for rolipram and Disease, Pulmonary
| Article | Year |
|---|---|
Amelioration of pulmonary dysfunction and neutrophilic inflammation by PPAR gamma agonist in LPS-exposed guinea pigs.
Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Escherichia coli Proteins; Guinea | 2009 |
Inhibition of cAMP degradation improves regulatory T cell-mediated suppression.
Topics: Animals; Cells, Cultured; Coculture Techniques; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Ty | 2009 |
Inhibitors of myosin light chain kinase and phosphodiesterase reduce ventilator-induced lung injury.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Capillary Permeability; Cyclic AMP; Drug Combinations | 2000 |
Comparison of PDE 4 inhibitors, rolipram and SB 207499 (ariflo), in a rat model of pulmonary neutrophilia.
Topics: Adrenalectomy; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Humans; Inflammation; I | 2001 |