rolipram has been researched along with Depressive Disorder in 12 studies
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Results of a randomized double-blind comparative trial versus imipramine involving 64 in-patients with Major Depressive Disorder (DSM III) in six independent centers will be presented and discussed." | 9.06 | Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine. ( Fellerer, K; Fichte, K; Fischer, G; Geyer, N; Hebenstreit, GF; Meya, U; Sastre-y-Hernández, M; Schöny, W; Schratzer, M; Soukop, W, 1989) |
| "50 mg dosage stood out from the others in almost all relevant parameters." | 6.67 | A multicenter double-blind study of three different doses of the new cAMP-phosphodiesterase inhibitor rolipram in patients with major depressive disorder. ( Bauer, H; Berner, P; Fleischhacker, WW; Gerlach, W; Hinterhuber, H; Jaklitsch, H; Pflug, B; Sastre-y-Hernández, M; Simhandl, C; Wolf, R, 1992) |
| " Results of a randomized double-blind comparative trial versus imipramine involving 64 in-patients with Major Depressive Disorder (DSM III) in six independent centers will be presented and discussed." | 5.06 | Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine. ( Fellerer, K; Fichte, K; Fischer, G; Geyer, N; Hebenstreit, GF; Meya, U; Sastre-y-Hernández, M; Schöny, W; Schratzer, M; Soukop, W, 1989) |
| "50 mg dosage stood out from the others in almost all relevant parameters." | 2.67 | A multicenter double-blind study of three different doses of the new cAMP-phosphodiesterase inhibitor rolipram in patients with major depressive disorder. ( Bauer, H; Berner, P; Fleischhacker, WW; Gerlach, W; Hinterhuber, H; Jaklitsch, H; Pflug, B; Sastre-y-Hernández, M; Simhandl, C; Wolf, R, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Itoh, T | 1 |
| Tokumura, M | 1 |
| Abe, K | 1 |
| Zeller, E | 1 |
| Stief, HJ | 1 |
| Pflug, B | 2 |
| Sastre-y-Hernández, M | 5 |
| Abou-Saleh, MT | 1 |
| Anderson, DN | 1 |
| Collins, J | 1 |
| Hughes, K | 1 |
| Cattell, RJ | 1 |
| Hamon, CG | 1 |
| Blair, JA | 1 |
| Fleischhacker, WW | 1 |
| Hinterhuber, H | 1 |
| Bauer, H | 1 |
| Berner, P | 1 |
| Simhandl, C | 1 |
| Wolf, R | 1 |
| Gerlach, W | 1 |
| Jaklitsch, H | 1 |
| Norman, TR | 1 |
| Judd, FK | 1 |
| Burrows, GD | 1 |
| Meya, U | 2 |
| Fichte, K | 3 |
| Scott, AI | 1 |
| Perini, AF | 1 |
| Shering, PA | 1 |
| Whalley, LJ | 1 |
| Overstreet, DH | 1 |
| Double, K | 1 |
| Schiller, GD | 1 |
| Hebenstreit, GF | 1 |
| Fellerer, K | 1 |
| Fischer, G | 1 |
| Geyer, N | 1 |
| Schöny, W | 1 |
| Schratzer, M | 3 |
| Soukop, W | 1 |
| Bobon, D | 1 |
| Breulet, M | 1 |
| Gerard-Vandenhove, MA | 1 |
| Guiot-Goffioul, F | 1 |
| Plomteux, G | 1 |
| Troisfontaines, B | 1 |
| von Frenckell, R | 1 |
| Wachtel, H | 1 |
| Bertolino, A | 1 |
| Crippa, D | 1 |
| di Dio, S | 1 |
| Musmeci, G | 1 |
| Porro, V | 1 |
| Rapisarda, V | 1 |
| Laux, G | 1 |
| Becker, T | 1 |
| Kühne, G | 1 |
| Lesch, KP | 1 |
| Riederer, P | 1 |
| Beckmann, H | 1 |
1 review available for rolipram and Depressive Disorder
| Article | Year |
|---|---|
New pharmacological approaches to the management of depression: from theory to clinical practice.
Topics: Antidepressive Agents; Benzamides; Depressive Disorder; Fluoxetine; Humans; Moclobemide; Pyridazines | 1992 |
7 trials available for rolipram and Depressive Disorder
| Article | Year |
|---|---|
Results of a phase II study of the antidepressant effect of rolipram.
Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Depressive Disorder, Major; Female; Huma | 1984 |
A multicenter double-blind study of three different doses of the new cAMP-phosphodiesterase inhibitor rolipram in patients with major depressive disorder.
Topics: Antidepressive Agents; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; H | 1992 |
[Onset of the antidepressive effect of rolipram, an antidepressant with a new mechanism of action, in comparison with imipramine].
Topics: Antidepressive Agents; Depressive Disorder; Drug Administration Schedule; Humans; Imipramine; Person | 1991 |
In-patient major depression: is rolipram as effective as amitriptyline?
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Depressive Disorder; Double-Blind Met | 1991 |
Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine.
Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Meth | 1989 |
Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Me | 1988 |
Rolipram versus imipramine in inpatients with major, "minor" or atypical depressive disorder: a double-blind double-dummy study aimed at testing a novel therapeutic approach.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Ho | 1988 |
4 other studies available for rolipram and Depressive Disorder
| Article | Year |
|---|---|
Effects of rolipram, a phosphodiesterase 4 inhibitor, in combination with imipramine on depressive behavior, CRE-binding activity and BDNF level in learned helplessness rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived | 2004 |
The role of pterins in depression and the effects of antidepressive therapy.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Biopterins; Clinical Trials as Topic; Depressive | 1995 |
Antidepressant effects of rolipram in a genetic animal model of depression: cholinergic supersensitivity and weight gain.
Topics: Albuterol; Animals; Antidepressive Agents; Avoidance Learning; Body Temperature; Brain; Depressive D | 1989 |
Clinical and biochemical effects of the selective phosphodiesterase inhibitor rolipram in depressed inpatients controlled by determination of plasma level.
Topics: Adult; Antidepressive Agents; Biogenic Monoamines; Depressive Disorder; Female; Humans; Male; Middle | 1988 |