rolipram has been researched along with Depression, Involutional in 7 studies
Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lyoo, CH | 1 |
| Zanotti-Fregonara, P | 2 |
| Zoghbi, SS | 4 |
| Liow, JS | 3 |
| Xu, R | 1 |
| Pike, VW | 4 |
| Zarate, CA | 4 |
| Fujita, M | 4 |
| Innis, RB | 4 |
| Richards, EM | 1 |
| Niciu, MJ | 1 |
| Ionescu, DF | 1 |
| Hong, J | 1 |
| Telu, S | 1 |
| Hines, CS | 3 |
| Mallinger, AG | 2 |
| Dickstein, LP | 1 |
| Zhang, Y | 2 |
| Drevets, WC | 2 |
| O'Donnell, JM | 2 |
| Xu, Y | 1 |
| Zhang, HT | 1 |
| Huang, Y | 1 |
| Jin, SL | 1 |
| Frith, SA | 1 |
| Suvarna, N | 1 |
| Conti, M | 1 |
| Zeller, E | 1 |
| Stief, HJ | 1 |
| Pflug, B | 1 |
| Sastre-y-Hernández, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE 4) in Depressed Patients[NCT00369798] | Phase 1 | 100 participants (Actual) | Interventional | 2006-08-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for rolipram and Depression, Involutional
| Article | Year |
|---|---|
Results of a phase II study of the antidepressant effect of rolipram.
Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Depressive Disorder, Major; Female; Huma | 1984 |
6 other studies available for rolipram and Depression, Involutional
| Article | Year |
|---|---|
Image-derived input function derived from a supervised clustering algorithm: methodology and validation in a clinical protocol using [11C](R)-rolipram.
Topics: Adult; Algorithms; Carbon Radioisotopes; Carotid Arteries; Case-Control Studies; Cluster Analysis; D | 2014 |
cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Antidepressive Agents; Brain; Carbon Radioisotopes; Case | 2017 |
Downregulation of brain phosphodiesterase type IV measured with 11C-(R)-rolipram positron emission tomography in major depressive disorder.
Topics: Adult; Animals; Brain; Brain Mapping; Carbon Isotopes; Cyclic Nucleotide Phosphodiesterases, Type 4; | 2012 |
Population-based input function and image-derived input function for [¹¹C](R)-rolipram PET imaging: methodology, validation and application to the study of major depressive disorder.
Topics: Adult; Antidepressive Agents; Brain; Carbon Radioisotopes; Depressive Disorder, Major; Female; Human | 2012 |
Evidence for global reduction in brain cyclic adenosine monophosphate signaling in depression.
Topics: Animals; Brain; Cyclic Nucleotide Phosphodiesterases, Type 4; Depressive Disorder, Major; Down-Regul | 2012 |
Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Animals; Antidepressive Agents; Behav | 2002 |