rolipram has been researched along with Demyelinating Diseases in 4 studies
Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rolipram promotes the maturation of OPCs, facilitates remyelination, and increases ERK phosphorylation." | 1.38 | Rolipram promotes remyelination possibly via MEK-ERK signal pathway in cuprizone-induced demyelination mouse. ( Liu, B; Liu, Y; Sun, X; Xiao, Z; Zhang, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paintlia, AS | 1 |
| Paintlia, MK | 1 |
| Singh, I | 1 |
| Singh, AK | 1 |
| Sun, X | 1 |
| Liu, Y | 1 |
| Liu, B | 1 |
| Xiao, Z | 1 |
| Zhang, L | 1 |
| Sommer, N | 1 |
| Martin, R | 1 |
| McFarland, HF | 1 |
| Quigley, L | 1 |
| Cannella, B | 1 |
| Raine, CS | 1 |
| Scott, DE | 1 |
| Löschmann, PA | 1 |
| Racke, MK | 1 |
| 't Hart, BA | 1 |
| van Meurs, M | 1 |
| Brok, HP | 1 |
| Massacesi, L | 1 |
| Bauer, J | 1 |
| Boon, L | 1 |
| Bontrop, RE | 1 |
| Laman, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison Between Clinical and MRI Multiple Sclerosis Activity and Expression of Human Endogenous Retrovirus Type W and Herpesvirus in Peripheral Blood of Patients[NCT02489877] | 84 participants (Anticipated) | Observational | 2015-07-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for rolipram and Demyelinating Diseases
| Article | Year |
|---|---|
Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis.
Topics: Animals; Demyelinating Diseases; Drug Synergism; Drug Therapy, Combination; Encephalomyelitis, Autoi | 2008 |
Rolipram promotes remyelination possibly via MEK-ERK signal pathway in cuprizone-induced demyelination mouse.
Topics: Animals; Blotting, Western; Brain; Cell Differentiation; Cuprizone; Demyelinating Diseases; Lysophos | 2012 |
Therapeutic potential of phosphodiesterase type 4 inhibition in chronic autoimmune demyelinating disease.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Autoimmune Diseases; Cell Count; Cells, Cultured; Cycl | 1997 |
A new primate model for multiple sclerosis in the common marmoset.
Topics: Acute Disease; Animals; Antibodies, Monoclonal; Autoimmune Diseases; Callithrix; CD40 Antigens; Cebi | 2000 |