rolipram has been researched along with Colonic Neoplasms in 2 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One of the major problems in treating colon cancer is chemoresistance to cytotoxic chemotherapeutic agents." | 1.34 | Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase. ( Baillie, GS; Brunton, VG; Frame, MC; Houslay, MD; Leslie, NR; McEwan, DG, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miklos, W | 1 |
| Heffeter, P | 1 |
| Pirker, C | 1 |
| Hager, S | 1 |
| Kowol, CR | 1 |
| van Schoonhoven, S | 1 |
| Stojanovic, M | 1 |
| Keppler, BK | 1 |
| Berger, W | 1 |
| McEwan, DG | 1 |
| Brunton, VG | 1 |
| Baillie, GS | 1 |
| Leslie, NR | 1 |
| Houslay, MD | 1 |
| Frame, MC | 1 |
2 other studies available for rolipram and Colonic Neoplasms
| Article | Year |
|---|---|
Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling.
Topics: Animals; Cell Line, Tumor; Colonic Neoplasms; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Res | 2016 |
Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell | 2007 |