Page last updated: 2024-11-04

rolipram and Cognition Disorders

rolipram has been researched along with Cognition Disorders in 11 studies

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"Treatment with rolipram increased expression of CREB and pCREB, reduced the inflammatory reaction (decreased TNF-α levels and increased IL-10 levels), and prevented cognitive impairment in these diabetic animals."1.42Activation of Hippocampal CREB by Rolipram Partially Recovers Balance Between TNF-α and IL-10 Levels and Improves Cognitive Deficits in Diabetic Rats. ( He, T; Li, W; Miao, Y; Wang, B; Zhong, Y; Zhu, Y, 2015)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Titus, DJ1
Sakurai, A1
Kang, Y1
Furones, C1
Jergova, S1
Santos, R1
Sick, TJ1
Atkins, CM1
Miao, Y2
He, T2
Zhu, Y2
Li, W2
Wang, B1
Zhong, Y2
Jabaris, SS1
Sumathy, H1
Girish, R1
Narayanan, S1
Sugumar, M1
Saravana Babu, C1
Thanikachalam, S1
Thanikachalam, M1
Yan, H1
Myeku, N1
Clelland, CL1
Emrani, S1
Kukushkin, NV1
Yu, WH1
Goldberg, AL1
Duff, KE1
Kelly, MP1
Stein, JM1
Vecsey, CG1
Favilla, C1
Yang, X1
Bizily, SF1
Esposito, MF1
Wand, G1
Kanes, SJ1
Abel, T1
Wang, C1
Yang, XM1
Zhuo, YY1
Zhou, H2
Lin, HB1
Cheng, YF1
Xu, JP1
Zhang, HT1
Giralt, A1
Saavedra, A1
Carretón, O1
Xifró, X1
Alberch, J1
Pérez-Navarro, E1
Ramos, BP1
Birnbaum, SG1
Lindenmayer, I1
Newton, SS1
Duman, RS1
Arnsten, AF1
Comery, TA1
Martone, RL1
Aschmies, S1
Atchison, KP1
Diamantidis, G1
Gong, X1
Kreft, AF1
Pangalos, MN1
Sonnenberg-Reines, J1
Jacobsen, JS1
Marquis, KL1
Costa, DA1
Cracchiolo, JR1
Bachstetter, AD1
Hughes, TF1
Bales, KR1
Paul, SM1
Mervis, RF1
Arendash, GW1
Potter, H1

Other Studies

11 other studies available for rolipram and Cognition Disorders

ArticleYear
Phosphodiesterase inhibition rescues chronic cognitive deficits induced by traumatic brain injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Mar-20, Volume: 33, Issue:12

    Topics: Animals; Brain Injuries; Chronic Disease; Cognition Disorders; Conditioning, Psychological; Cyclic A

2013
Activation of Hippocampal CREB by Rolipram Partially Recovers Balance Between TNF-α and IL-10 Levels and Improves Cognitive Deficits in Diabetic Rats.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:8

    Topics: Animals; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Experi

2015
Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system.
    Brain research, 2015, Oct-05, Volume: 1622

    Topics: Adrenergic alpha-2 Receptor Agonists; Aminopyridines; Animals; Antihypertensive Agents; Benzamides;

2015
Rolipram-induced improvement of cognitive function correlates with changes in hippocampal CREB phosphorylation, BDNF and Arc protein levels.
    Neuroscience letters, 2016, Jan-01, Volume: 610

    Topics: Animals; Apoptosis Regulatory Proteins; Brain-Derived Neurotrophic Factor; Cognition; Cognition Diso

2016
Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling.
    Nature medicine, 2016, Volume: 22, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cognition; Cognition Disorders; Cyclic AMP; Cyclic AMP-Dependent P

2016
Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia.
    Molecular psychiatry, 2009, Volume: 14, Issue:4

    Topics: Acetylcysteine; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; Animals, Newborn;

2009
The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats.
    The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:6

    Topics: Amyloid beta-Peptides; Animals; Apoptosis; Avoidance Learning; bcl-2-Associated X Protein; Cognition

2012
Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease.
    Human molecular genetics, 2011, Nov-01, Volume: 20, Issue:21

    Topics: Animals; Calcineurin; Cognition Disorders; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide P

2011
Dysregulation of protein kinase a signaling in the aged prefrontal cortex: new strategy for treating age-related cognitive decline.
    Neuron, 2003, Nov-13, Volume: 40, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aging; Animals; Cognition Disorders; Cyclic AMP; Cyclic AMP Res

2003
Acute gamma-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Sep-28, Volume: 25, Issue:39

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-P

2005
Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms.
    Neurobiology of aging, 2007, Volume: 28, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal;

2007