rolipram has been researched along with Bronchial Spasm in 7 studies
Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Roflumilast did not inhibit serotonin-induced bronchoconstriction 4." | 5.33 | Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors. ( Beume, R; Bundschuh, DS; Marx, D; Wohlsen, A; Wollin, L, 2006) |
| " Selected compounds have also been examined for their activities in inhibiting histamine-induced bronchospasm in anaesthetized guinea pigs." | 3.69 | Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues. ( Ashton, MJ; Cook, DC; Fenton, G; Karlsson, JA; Palfreyman, MN; Raeburn, D; Ratcliffe, AJ; Souness, JE; Thurairatnam, S; Vicker, N, 1994) |
| " We have investigated the effects of RP 73401, a novel, potent and highly selective cyclic nucleotide phosphodiesterase (PDE) type IV inhibitor, in guinea-pig and rat models of bronchoconstriction and allergic inflammation." | 3.69 | Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor. ( Battram, CH; Jordan, R; Lewis, SA; Raeburn, D; Sharma, S; Souness, JE; Tomkinson, A; Underwood, SL; Webber, SE; Woodman, VR, 1994) |
| "Roflumilast did not inhibit serotonin-induced bronchoconstriction 4." | 1.33 | Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors. ( Beume, R; Bundschuh, DS; Marx, D; Wohlsen, A; Wollin, L, 2006) |
| "Treatment with rolipram, but not theophylline, prevented the increase in responsiveness to inhaled histamine 24 h after antigen challenge." | 1.29 | Effects of theophylline and rolipram on antigen-induced airway responses in neonatally immunized rabbits. ( Blake, SM; Gozzard, N; Herd, CM; Higgs, GA; Holbrook, M; Hughes, B; Page, CP, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashton, MJ | 1 |
| Cook, DC | 1 |
| Fenton, G | 1 |
| Karlsson, JA | 1 |
| Palfreyman, MN | 1 |
| Raeburn, D | 2 |
| Ratcliffe, AJ | 1 |
| Souness, JE | 2 |
| Thurairatnam, S | 1 |
| Vicker, N | 1 |
| Wollin, L | 1 |
| Bundschuh, DS | 1 |
| Wohlsen, A | 1 |
| Marx, D | 1 |
| Beume, R | 1 |
| Underwood, SL | 1 |
| Lewis, SA | 1 |
| Woodman, VR | 1 |
| Battram, CH | 1 |
| Tomkinson, A | 1 |
| Sharma, S | 1 |
| Jordan, R | 1 |
| Webber, SE | 1 |
| Underwood, DC | 1 |
| Kotzer, CJ | 1 |
| Bochnowicz, S | 1 |
| Osborn, RR | 1 |
| Luttmann, MA | 1 |
| Hay, DW | 1 |
| Torphy, TJ | 1 |
| Gozzard, N | 1 |
| Herd, CM | 1 |
| Blake, SM | 1 |
| Holbrook, M | 1 |
| Hughes, B | 1 |
| Higgs, GA | 1 |
| Page, CP | 1 |
| Yamagata, S | 1 |
| Wada, K | 1 |
| Sugaya, T | 1 |
| Oka, K | 1 |
| Kaminuma, O | 1 |
| Kikkawa, H | 1 |
| Ikezawa, K | 1 |
| Billah, MM | 1 |
| Cooper, N | 1 |
| Minnicozzi, M | 1 |
| Warneck, J | 1 |
| Wang, P | 1 |
| Hey, JA | 1 |
| Kreutner, W | 1 |
| Rizzo, CA | 1 |
| Smith, SR | 1 |
| Young, S | 1 |
| Chapman, RW | 1 |
| Dyke, H | 1 |
| Shih, NY | 1 |
| Piwinski, JJ | 1 |
| Cuss, FM | 1 |
| Montana, J | 1 |
| Ganguly, AK | 1 |
| Egan, RW | 1 |
1 trial available for rolipram and Bronchial Spasm
| Article | Year |
|---|---|
Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase 4 inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adolescent; Adult; Aged; Animals; Anti-Asthmatic Agents; Bindin | 2002 |
6 other studies available for rolipram and Bronchial Spasm
| Article | Year |
|---|---|
Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Asthma; Benzamides; Bronchial Spasm; Eosinophil | 1994 |
Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Aminopyridines; Animals; Benzamides; Bron | 2006 |
Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor.
Topics: Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bronchial Hyperreactivity; | 1994 |
Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs.
Topics: Animals; Antigens; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Drug Synergis | 1994 |
Effects of theophylline and rolipram on antigen-induced airway responses in neonatally immunized rabbits.
Topics: Airway Resistance; Alternaria; Animals; Anti-Inflammatory Agents; Antigens, Fungal; Asthma; Bronchia | 1996 |
Bronchial anti-spasmogenic effects and selectivity of T-440, phosphodiesterase type 4 inhibitor, in the dog.
Topics: Animals; Blood Pressure; Bronchial Spasm; Bronchoconstriction; Chromatography, High Pressure Liquid; | 1997 |