rolipram has been researched along with Brain Neoplasms in 6 studies
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bradykinin causes a concentration-dependent, transient rise in intracellular Ca2+ and a sustained inhibition of forskolin-, dopamine- and 5'-N-ethyl-carboxamidoadenosine (NECA)-stimulated cAMP accumulation in D384 astrocytoma cells." | 7.68 | Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase. ( Altiok, N; Fredholm, BB, 1993) |
| "Bradykinin causes a concentration-dependent, transient rise in intracellular Ca2+ and a sustained inhibition of forskolin-, dopamine- and 5'-N-ethyl-carboxamidoadenosine (NECA)-stimulated cAMP accumulation in D384 astrocytoma cells." | 3.68 | Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase. ( Altiok, N; Fredholm, BB, 1993) |
| "Rolipram-treated A172 or U87MG cell survival was lower in the presence of forskolin, adenylate cyclase activator, than that in its absence." | 1.38 | Phosphodiesterase inhibitors control A172 human glioblastoma cell death through cAMP-mediated activation of protein kinase A and Epac1/Rap1 pathways. ( Kim, HM; Lee, GH; Lee, JW; Lee, MS; Moon, EY, 2012) |
| "As favorable outcomes from malignant brain tumors remain limited by poor survival and treatment-related toxicity, novel approaches to cure are essential." | 1.35 | Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression. ( Goldhoff, P; Hope, A; Jackson, E; Limbrick, DD; Perry, A; Piwnica-Worms, D; Rubin, JB; Warrington, NM; Woerner, BM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramezani, S | 1 |
| Vousooghi, N | 1 |
| Ramezani Kapourchali, F | 1 |
| Yousefzadeh-Chabok, S | 1 |
| Reihanian, Z | 1 |
| Alizadeh, AM | 1 |
| Khodayari, S | 1 |
| Khodayari, H | 1 |
| Goldhoff, P | 1 |
| Warrington, NM | 1 |
| Limbrick, DD | 1 |
| Hope, A | 1 |
| Woerner, BM | 2 |
| Jackson, E | 2 |
| Perry, A | 2 |
| Piwnica-Worms, D | 2 |
| Rubin, JB | 2 |
| Schmidt, AL | 1 |
| de Farias, CB | 1 |
| Abujamra, AL | 1 |
| Brunetto, AL | 1 |
| Schwartsmann, G | 1 |
| Roesler, R | 1 |
| Moon, EY | 1 |
| Lee, GH | 1 |
| Lee, MS | 1 |
| Kim, HM | 1 |
| Lee, JW | 1 |
| Yang, L | 1 |
| Altiok, N | 1 |
| Fredholm, BB | 1 |
6 other studies available for rolipram and Brain Neoplasms
| Article | Year |
|---|---|
Rolipram optimizes therapeutic effect of bevacizumab by enhancing proapoptotic, antiproliferative signals in a glioblastoma heterotopic model.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevaciz | 2019 |
Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.
Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Li | 2008 |
Phosphodiesterase-4 inhibition and brain tumor growth.
Topics: Animals; Brain Neoplasms; Cerebellar Neoplasms; Cyclic Nucleotide Phosphodiesterases, Type 4; Medull | 2009 |
Phosphodiesterase inhibitors control A172 human glioblastoma cell death through cAMP-mediated activation of protein kinase A and Epac1/Rap1 pathways.
Topics: 1-Methyl-3-isobutylxanthine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neopla | 2012 |
Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo.
Topics: Animals; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Chemokine CXCL12; Chemokines, CXC | 2007 |
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibito | 1993 |