rolipram has been researched along with Brain Edema in 3 studies
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rolipram is a multifaceted antiinflammatory and antithrombotic compound that protects from ischemic neurodegeneration in clinically meaningful settings." | 5.39 | The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood-brain-barrier damage, inflammation and thrombosis. ( Brede, M; Göb, E; Heydenreich, N; Kleinschnitz, C; Kraft, P; Meuth, SG; Schwarz, T, 2013) |
| "Rolipram is a multifaceted antiinflammatory and antithrombotic compound that protects from ischemic neurodegeneration in clinically meaningful settings." | 1.39 | The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood-brain-barrier damage, inflammation and thrombosis. ( Brede, M; Göb, E; Heydenreich, N; Kleinschnitz, C; Kraft, P; Meuth, SG; Schwarz, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Q | 1 |
| Peng, Y | 1 |
| Fan, L | 1 |
| Xu, H | 1 |
| He, P | 1 |
| Cao, S | 1 |
| Li, J | 1 |
| Chen, T | 1 |
| Ruan, W | 1 |
| Chen, G | 1 |
| Kraft, P | 1 |
| Schwarz, T | 1 |
| Göb, E | 1 |
| Heydenreich, N | 1 |
| Brede, M | 1 |
| Meuth, SG | 1 |
| Kleinschnitz, C | 1 |
| Folcik, VA | 1 |
| Smith, T | 1 |
| O'Bryant, S | 1 |
| Kawczak, JA | 1 |
| Zhu, B | 1 |
| Sakurai, H | 1 |
| Kajiwara, A | 1 |
| Staddon, JM | 1 |
| Glabinski, A | 1 |
| Chernosky, AL | 1 |
| Tani, M | 1 |
| Johnson, JM | 1 |
| Tuohy, VK | 1 |
| Rubin, LL | 1 |
| Ransohoff, RM | 1 |
3 other studies available for rolipram and Brain Edema