rolipram has been researched along with Blood Poisoning in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| ", acutely restored capillary perfusion in a bell-shaped dose-response effect with 1 mg/kg being the lowest most efficacious dose." | 5.39 | Rolipram improves renal perfusion and function during sepsis in the mouse. ( Gokden, N; Holthoff, JH; Mayeux, PR; Patil, NK; Wang, Z, 2013) |
| "We induced polymicrobial sepsis using the colon ascendens stent peritonitis (CASP) model in which we performed macrohemodynamic and microhemodynamic monitoring with and without systemic intravenous application of different doses of PD-4-I rolipram in Sprague-Dawley rats over 26 h." | 3.80 | Phosphodiesterase 4 inhibition dose dependently stabilizes microvascular barrier functions and microcirculation in a rodent model of polymicrobial sepsis. ( Baar, W; Flemming, S; Germer, CT; Meir, M; Roewer, N; Schick, MA; Schlegel, N; Wollborn, J; Wunder, C, 2014) |
| "Bacteremia-induced sepsis is a leading cause of mortality in intensive care units." | 1.62 | Multifunctional lipid-based nanocarriers with antibacterial and anti-inflammatory activities for treating MRSA bacteremia in mice. ( Alalaiwe, A; Dai, YS; Fang, JY; Liao, CC; Liu, FC; Yang, SC; Yu, HP, 2021) |
| ", acutely restored capillary perfusion in a bell-shaped dose-response effect with 1 mg/kg being the lowest most efficacious dose." | 1.39 | Rolipram improves renal perfusion and function during sepsis in the mouse. ( Gokden, N; Holthoff, JH; Mayeux, PR; Patil, NK; Wang, Z, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Song, G | 1 |
| Zhu, X | 1 |
| Li, J | 1 |
| Hu, D | 1 |
| Zhao, D | 1 |
| Liao, Y | 1 |
| Lin, J | 1 |
| Zhang, LH | 2 |
| Cui, ZN | 2 |
| Hu, DK | 1 |
| Zhao, DS | 1 |
| He, M | 1 |
| Jin, HW | 1 |
| Tang, YM | 1 |
| Song, GP | 1 |
| Liao, CC | 1 |
| Yu, HP | 1 |
| Yang, SC | 1 |
| Alalaiwe, A | 1 |
| Dai, YS | 1 |
| Liu, FC | 1 |
| Fang, JY | 1 |
| Yang, JX | 1 |
| Hsieh, KC | 1 |
| Chen, YL | 1 |
| Lee, CK | 1 |
| Conti, M | 1 |
| Chuang, TH | 1 |
| Wu, CP | 1 |
| Jin, SC | 1 |
| Holthoff, JH | 1 |
| Wang, Z | 1 |
| Patil, NK | 1 |
| Gokden, N | 1 |
| Mayeux, PR | 1 |
| Flemming, S | 1 |
| Schlegel, N | 1 |
| Wunder, C | 1 |
| Meir, M | 1 |
| Baar, W | 1 |
| Wollborn, J | 1 |
| Roewer, N | 1 |
| Germer, CT | 1 |
| Schick, MA | 1 |
| Monneret, G | 1 |
| Arpin, M | 1 |
| Venet, F | 1 |
| Maghni, K | 1 |
| Debard, AL | 1 |
| Pachot, A | 1 |
| Lepape, A | 1 |
| Bienvenu, J | 1 |
7 other studies available for rolipram and Blood Poisoning
| Article | Year |
|---|---|
Rational design of conformationally constrained oxazolidinone-fused 1,2,3,4-tetrahydroisoquinoline derivatives as potential PDE4 inhibitors.
Topics: Animals; Asthma; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Drug Design; | 2017 |
Synthesis and bioactivity of 3,5-dimethylpyrazole derivatives as potential PDE4 inhibitors.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Inhibitory Concentration 50; Mice; Phosphodiesterase | 2018 |
Multifunctional lipid-based nanocarriers with antibacterial and anti-inflammatory activities for treating MRSA bacteremia in mice.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacteremia; Ciprofloxacin; Disease Models, | 2021 |
Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages.
Topics: Animals; Cell Survival; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependen | 2017 |
Rolipram improves renal perfusion and function during sepsis in the mouse.
Topics: Acute Kidney Injury; Animals; Blood Flow Velocity; Disease Models, Animal; Glomerular Filtration Rat | 2013 |
Phosphodiesterase 4 inhibition dose dependently stabilizes microvascular barrier functions and microcirculation in a rodent model of polymicrobial sepsis.
Topics: Animals; Coinfection; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium; Hemodyn | 2014 |
Calcitonin gene related peptide and N-procalcitonin modulate CD11b upregulation in lipopolysaccharide activated monocytes and neutrophils.
Topics: Biomarkers; Calcitonin; Calcitonin Gene-Related Peptide; CD11b Antigen; Cells, Cultured; Chemotaxis, | 2003 |