rolipram has been researched along with Anesthesia in 11 studies
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to investigate the mode of action of luteolin on phisphodiesterase (PDE) 1-5, and the possible adverse effects, such as nausea, vomiting, and gastric hypersecretion, determined by replacing [(3)H]-rolipram binding and reversing xylazine/ketamine-induced anesthesia." | 7.76 | Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [3H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia. ( Chen, JH; Han, CY; Ko, WC; Lai, CY; Yu, MC, 2010) |
| "The affinities of genistein on phosphodiesterase (PDE)1-4 and cause of gastrointestinal adverse effects of genistein remain unclear." | 1.36 | Genistein, a competitive PDE1-4 inhibitor, may bind on high-affinity rolipram binding sites of brain cell membranes and then induce gastrointestinal adverse effects. ( Chen, CM; Han, CY; Ko, WC; Lai, CY; Lai, YH; Lin, LH; Shih, CH, 2010) |
| "Pretreatment with rolipram decreased the duration of ventricular tachycardia without any change in the incidences of dysrhythmias or the mortality rate." | 1.32 | Effects of rolipram, pimobendan and zaprinast on ischaemia-induced dysrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat. ( Aleixandre, F; Carceles, MD; Fuente, T; Laorden, ML; López-Vidal, J, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García, AM | 1 |
| Brea, J | 1 |
| Morales-García, JA | 1 |
| Perez, DI | 1 |
| González, A | 1 |
| Alonso-Gil, S | 1 |
| Gracia-Rubio, I | 1 |
| Ros-Simó, C | 1 |
| Conde, S | 1 |
| Cadavid, MI | 1 |
| Loza, MI | 1 |
| Perez-Castillo, A | 1 |
| Valverde, O | 1 |
| Martinez, A | 1 |
| Gil, C | 1 |
| Yu, MC | 1 |
| Chen, JH | 1 |
| Lai, CY | 2 |
| Han, CY | 2 |
| Ko, WC | 2 |
| Shih, CH | 1 |
| Lin, LH | 1 |
| Lai, YH | 1 |
| Chen, CM | 1 |
| Carceles, MD | 1 |
| Aleixandre, F | 1 |
| Fuente, T | 1 |
| López-Vidal, J | 1 |
| Laorden, ML | 1 |
| Büyüknacar, HS | 1 |
| Kumcu, EK | 1 |
| Göçmen, C | 1 |
| Onder, S | 1 |
| Turner, NC | 1 |
| Dolan, JS | 1 |
| Grimsditch, D | 1 |
| Lamb, J | 1 |
| Worby, A | 1 |
| Murray, KJ | 1 |
| Coates, WJ | 1 |
| Warrington, BH | 1 |
| Underwood, DC | 1 |
| Osborn, RR | 1 |
| Novak, LB | 1 |
| Matthews, JK | 1 |
| Newsholme, SJ | 1 |
| Undem, BJ | 1 |
| Hand, JM | 1 |
| Torphy, TJ | 1 |
| McVey, M | 1 |
| Perrone, MH | 1 |
| Clark, KL | 1 |
| Tanahashi, M | 1 |
| Hara, S | 1 |
| Yoshida, M | 1 |
| Suzuki-Kusaba, M | 1 |
| Yokoyama, H | 1 |
| Hosono, M | 1 |
| Hisa, H | 1 |
| Satoh, S | 1 |
| Robichaud, A | 1 |
| Savoie, C | 1 |
| Stamatiou, PB | 1 |
| Tattersall, FD | 1 |
| Chan, CC | 1 |
| Shah, MK | 1 |
| Kadowitz, PJ | 1 |
11 other studies available for rolipram and Anesthesia
| Article | Year |
|---|---|
Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors.
Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Cell Survival; Ch | 2014 |
Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [3H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia.
Topics: Anesthesia; Animals; Binding, Competitive; Female; Guinea Pigs; Ketamine; Luteolin; Male; Mice; Phos | 2010 |
Genistein, a competitive PDE1-4 inhibitor, may bind on high-affinity rolipram binding sites of brain cell membranes and then induce gastrointestinal adverse effects.
Topics: Anesthesia; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Cyclic Nucleotide Ph | 2010 |
Effects of rolipram, pimobendan and zaprinast on ischaemia-induced dysrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Anesthesia; Animals; Arrhy | 2003 |
Effect of phosphodiesterase type 4 inhibitor rolipram on cyclophosphamide-induced cystitis in rats.
Topics: Anesthesia; Animals; Antineoplastic Agents, Alkylating; Calcium Channel Blockers; Cyclophosphamide; | 2008 |
Pulmonary effects of type V cyclic GMP specific phosphodiesterase inhibition in the anaesthetized guinea-pig.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Anesthesia; Animals; Bronchoconstriction; Cyclic GMP; Guanidine | 1994 |
Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram.
Topics: Anesthesia; Animals; Antigens; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Consciousness; Cyc | 1993 |
Does tumor necrosis factor-alpha (TNF-alpha) contribute to myocardial reperfusion injury in anesthetized rats?
Topics: Anesthesia; Animals; Blood Pressure; Enzyme-Linked Immunosorbent Assay; Heart Rate; Male; Myocardial | 1999 |
Effects of NKH477 on renal functions and cyclic AMP production in anesthetized dogs.
Topics: Anesthesia; Animals; Blood Pressure; Cardiotonic Agents; Colforsin; Cyclic AMP; Dogs; Female; Kidney | 1999 |
PDE4 inhibitors induce emesis in ferrets via a noradrenergic pathway.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesth | 2001 |
Cyclic adenosine monophosphate-dependent vascular responses to purinergic agonists adenosine triphosphate and uridine triphosphate in the anesthetized mouse.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Triphosphate; Anesthesia; Animals; Blood Pressure; Cy | 2002 |