rolipram has been researched along with Alloxan Diabetes in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with rolipram increased expression of CREB and pCREB, reduced the inflammatory reaction (decreased TNF-α levels and increased IL-10 levels), and prevented cognitive impairment in these diabetic animals." | 1.42 | Activation of Hippocampal CREB by Rolipram Partially Recovers Balance Between TNF-α and IL-10 Levels and Improves Cognitive Deficits in Diabetic Rats. ( He, T; Li, W; Miao, Y; Wang, B; Zhong, Y; Zhu, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Arcaro, CA | 1 |
| Assis, RP | 1 |
| Oliveira, JO | 1 |
| Zanon, NM | 1 |
| Paula-Gomes, S | 1 |
| Navegantes, LCC | 1 |
| Kettelhut, IC | 1 |
| Brunetti, IL | 1 |
| Baviera, AM | 1 |
| Miao, Y | 2 |
| He, T | 2 |
| Zhu, Y | 2 |
| Li, W | 2 |
| Wang, B | 1 |
| Zhong, Y | 2 |
| Yan, H | 1 |
| Barreto, EO | 1 |
| Carvalho, VF | 1 |
| Lagente, V | 1 |
| Lugnier, C | 1 |
| Cordeiro, RS | 1 |
| Martins, MA | 1 |
| E Silva, PM | 1 |
| Van Tine, BA | 1 |
| Azizeh, BY | 1 |
| Trivedi, D | 1 |
| Phelps, JR | 1 |
| Houslay, MD | 1 |
| Johnson, DG | 1 |
| Hruby, VJ | 1 |
| Usta, C | 1 |
| Sadan, G | 1 |
6 other studies available for rolipram and Alloxan Diabetes
| Article | Year |
|---|---|
Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calpain; Caspase 3; Cyclic AMP; Cyclic AMP-Dependent P | 2021 |
Activation of Hippocampal CREB by Rolipram Partially Recovers Balance Between TNF-α and IL-10 Levels and Improves Cognitive Deficits in Diabetic Rats.
Topics: Animals; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Diabetes Mellitus, Experi | 2015 |
Rolipram-induced improvement of cognitive function correlates with changes in hippocampal CREB phosphorylation, BDNF and Arc protein levels.
Topics: Animals; Apoptosis Regulatory Proteins; Brain-Derived Neurotrophic Factor; Cognition; Cognition Diso | 2016 |
Increased levels of cyclic adenosine monophosphate contribute to the hyporesponsiveness of mast cells in alloxan diabetes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antigens; Bradykinin; Bucladesine; Cell Degranulation; | 2004 |
Low level cyclic adenosine 3',5'-monophosphate accumulation analysis of [des-His1, des- Phe6, Glu9] glucagon-NH2 identifies glucagon antagonists from weak partial agonists/antagonists.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Amrinone; Animals; Blood Glucose; Cyclic A | 1996 |
Comparison of the effects of selective III, IV and nonselective phosphodiesterase inhibitors on isolated tracheal preparations in streptozotocin-diabetic rats.
Topics: Amrinone; Animals; Carbachol; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dose-Response Rel | 2000 |