rolipram has been researched along with Allodynia in 10 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The objective of the present paper was to evaluate the relevance of neuronal balance of cyclic AMP and cyclic GMP concentration for functional regulation of nociceptor sensitivity during inflammation." | 3.70 | Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. ( Cunha, FQ; Ferreira, SH; Teixeira, MM, 1999) |
| "Pharmac." | 1.29 | Delayed sympathectomy after a prolonged hyperalgesia results in a subsequent enhanced acute hyperalgesic response. ( Aley, KO; Kinnman, E; Levine, JD, 1996) |
| "The duration of this hyperalgesia was prolonged by the phosphodiesterase inhibitors, isobutylmethylxanthine and rolipram." | 1.28 | Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia. ( Levine, JD; Taiwo, YO, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chłoń-Rzepa, G | 1 |
| Ślusarczyk, M | 1 |
| Jankowska, A | 1 |
| Gawalska, A | 1 |
| Bucki, A | 1 |
| Kołaczkowski, M | 1 |
| Świerczek, A | 1 |
| Pociecha, K | 1 |
| Wyska, E | 1 |
| Zygmunt, M | 1 |
| Kazek, G | 1 |
| Sałat, K | 1 |
| Pawłowski, M | 1 |
| Megat, S | 1 |
| Hugel, S | 1 |
| Journée, SH | 1 |
| Bohren, Y | 1 |
| Lacaud, A | 1 |
| Lelièvre, V | 1 |
| Doridot, S | 1 |
| Villa, P | 1 |
| Bourguignon, JJ | 1 |
| Salvat, E | 1 |
| Schlichter, R | 1 |
| Freund-Mercier, MJ | 1 |
| Yalcin, I | 1 |
| Barrot, M | 1 |
| Guo, CH | 1 |
| Bai, L | 1 |
| Wu, HH | 1 |
| Yang, J | 1 |
| Cai, GH | 1 |
| Wang, X | 1 |
| Wu, SX | 1 |
| Ma, W | 1 |
| Bretzner, F | 1 |
| Plemel, JR | 1 |
| Liu, J | 1 |
| Richter, M | 1 |
| Roskams, AJ | 1 |
| Tetzlaff, W | 1 |
| Ouseph, AK | 2 |
| Khasar, SG | 1 |
| Levine, JD | 5 |
| Aley, KO | 1 |
| Kinnman, E | 1 |
| Cunha, FQ | 1 |
| Teixeira, MM | 1 |
| Ferreira, SH | 1 |
| Taiwo, YO | 2 |
| Heller, PH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Regeneration in Cervical Degenerative Myelopathy - a Multi-centre, Double-blind, Randomised, Placebo Controlled Trial Assessing the Efficacy of Ibudilast as an Adjuvant Treatment to Decompressive Surgery for Degenerative Cervical Myelopathy[NCT04631471] | Phase 3 | 400 participants (Anticipated) | Interventional | 2021-12-22 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for rolipram and Allodynia
| Article | Year |
|---|---|
Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain.
Topics: Amides; Analgesics; Animals; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phospho | 2018 |
Antiallodynic action of phosphodiesterase inhibitors in a mouse model of peripheral nerve injury.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Mice; Neuralgia; Peripheral Nerve Injuries; Phosphodi | 2022 |
The analgesic effect of rolipram is associated with the inhibition of the activation of the spinal astrocytic JNK/CCL2 pathway in bone cancer pain.
Topics: Analgesics; Animals; Anthracenes; Astrocytes; Bone Neoplasms; Cancer Pain; Chemokine CCL2; Cyclic Nu | 2016 |
Combination of olfactory ensheathing cells with local versus systemic cAMP treatment after a cervical rubrospinal tract injury.
Topics: Animals; Axons; Cell Transplantation; Cyclic AMP; Disease Models, Animal; Glial Fibrillary Acidic Pr | 2010 |
Multiple second messenger systems act sequentially to mediate rolipram-induced prolongation of prostaglandin E2-induced mechanical hyperalgesia in the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminoquinolines; Animals; Calcium; Carrier Proteins; Cyclic | 1995 |
Alpha 1-adrenoceptor-mediated sympathetically dependent mechanical hyperalgesia in the rat.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Autonomic Fibers, Postganglionic; Autonomic Fibers, P | 1995 |
Delayed sympathectomy after a prolonged hyperalgesia results in a subsequent enhanced acute hyperalgesic response.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Drug Combinations; Hyperalgesia; Mal | 1996 |
Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia.
Topics: Animals; Bradykinin; Carrageenan; Cyclic AMP; Cyclic GMP; Dinoprostone; Dopamine; Hyperalgesia; Infl | 1999 |
Mediation of serotonin hyperalgesia by the cAMP second messenger system.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy- | 1992 |
Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dinoprost | 1991 |