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rolipram and Alcohol Drinking

rolipram has been researched along with Alcohol Drinking in 6 studies

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
"Using three rodent models of ethanol abstinence, we examined the effects of rolipram, a prototypical, selective PDE4 inhibitor, on (1) anxiety-like behavior induced by repeated ethanol abstinence in the elevated plus maze test in fawn-hooded (FH/Wjd) rats, (2) anxiety-like behavior in the open-field test and light-dark transition test following acute ethanol abstinence in C57BL/6J mice, and (3) anxiety- and depressive-like behavior induced by protracted ethanol abstinence in the elevated plus maze, forced-swim, and tail-suspension tests in C57BL/6J mice."7.85Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents. ( Fei, N; Gong, MF; Liang, JH; Pan, JC; Wen, RT; Xu, JP; Xu, Y; Zhang, HT; Zhou, YM, 2017)
"Gabapentin increased ethanol (EtOH) binge-like alcohol drinking in female HDID-1 and HS/NPT mice."3.96Effects of Pharmacologically Targeting Neuroimmune Pathways on Alcohol Drinking in Mice Selectively Bred to Drink to Intoxication. ( Blednov, YA; Crabbe, JC; Metten, P; Ozburn, AR; Potretzke, S; Townsley, KG, 2020)
"Using three rodent models of ethanol abstinence, we examined the effects of rolipram, a prototypical, selective PDE4 inhibitor, on (1) anxiety-like behavior induced by repeated ethanol abstinence in the elevated plus maze test in fawn-hooded (FH/Wjd) rats, (2) anxiety-like behavior in the open-field test and light-dark transition test following acute ethanol abstinence in C57BL/6J mice, and (3) anxiety- and depressive-like behavior induced by protracted ethanol abstinence in the elevated plus maze, forced-swim, and tail-suspension tests in C57BL/6J mice."3.85Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents. ( Fei, N; Gong, MF; Liang, JH; Pan, JC; Wen, RT; Xu, JP; Xu, Y; Zhang, HT; Zhou, YM, 2017)
"Exp 1 determined the dose-response effects of PDE4 inhibitors, rolipram, and Ro 20-1724, on 2 h/day free-choice EtOH intake by adult P and HAD1 rats."1.42Reduction of alcohol drinking of alcohol-preferring (P) and high-alcohol drinking (HAD1) rats by targeting phosphodiesterase-4 (PDE4). ( Bell, RL; Ding, ZM; Franklin, KM; Hauser, SR; Lasek, AW; McBride, WJ; McClintick, J, 2015)
"Alcohol dependence is a complex psychiatric disorder demanding development of novel pharmacotherapies."1.38The phosphodiesterase-4 (PDE4) inhibitor rolipram decreases ethanol seeking and consumption in alcohol-preferring Fawn-Hooded rats. ( Lawrence, AJ; Liang, JH; Liu, Q; Qin, WJ; Wang, WP; Wen, RT; Zhang, HT; Zhang, M, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Ozburn, AR1
Metten, P1
Potretzke, S1
Townsley, KG1
Blednov, YA1
Crabbe, JC1
Liu, X1
Hao, PD1
Yang, MF1
Sun, JY1
Mao, LL1
Fan, CD1
Zhang, ZY1
Li, DW1
Yang, XY1
Sun, BL1
Zhang, HT4
Gong, MF1
Wen, RT2
Xu, Y1
Pan, JC1
Fei, N1
Zhou, YM1
Xu, JP1
Liang, JH2
Franklin, KM1
Hauser, SR1
Lasek, AW1
McClintick, J1
Ding, ZM1
McBride, WJ1
Bell, RL1
Hu, W1
Lu, T1
Chen, A1
Huang, Y1
Hansen, R1
Chandler, LJ1
Zhang, M1
Qin, WJ1
Liu, Q1
Wang, WP1
Lawrence, AJ1

Other Studies

6 other studies available for rolipram and Alcohol Drinking

ArticleYear
Effects of Pharmacologically Targeting Neuroimmune Pathways on Alcohol Drinking in Mice Selectively Bred to Drink to Intoxication.
    Alcoholism, clinical and experimental research, 2020, Volume: 44, Issue:2

    Topics: Alcohol Drinking; Alcoholic Intoxication; Alkanesulfonates; Animals; Binge Drinking; Dose-Response R

2020
The phosphodiesterase-4 inhibitor roflumilast decreases ethanol consumption in C57BL/6J mice.
    Psychopharmacology, 2017, Volume: 234, Issue:16

    Topics: Alcohol Drinking; Aminopyridines; Animals; Benzamides; Cyclic Nucleotide Phosphodiesterases, Type 4;

2017
Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents.
    Psychopharmacology, 2017, Volume: 234, Issue:20

    Topics: Alcohol Abstinence; Alcohol Drinking; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety;

2017
Reduction of alcohol drinking of alcohol-preferring (P) and high-alcohol drinking (HAD1) rats by targeting phosphodiesterase-4 (PDE4).
    Psychopharmacology, 2015, Volume: 232, Issue:13

    Topics: Alcohol Drinking; Animals; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship,

2015
Inhibition of phosphodiesterase-4 decreases ethanol intake in mice.
    Psychopharmacology, 2011, Volume: 218, Issue:2

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alcohol Drinking; Animals; Brain; Central Nervous Sy

2011
The phosphodiesterase-4 (PDE4) inhibitor rolipram decreases ethanol seeking and consumption in alcohol-preferring Fawn-Hooded rats.
    Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:12

    Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Dose-Response Rel

2012