rolipram has been researched along with Akinetic-Rigid Variant of Huntington Disease in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rolipram induces an increase in pERK expression in these interneurons." | 1.38 | Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition. ( Anzilotti, S; Bernardi, G; Colucci D'Amato, L; Dato, C; Fusco, FR; Giampà, C; Laurenti, D; Leuti, A; Melone, MA; Perrone, L, 2012) |
| "Rolipram was effective in increasing significantly the levels of activated CREB and of BDNF the striatal spiny neurons, which might account for the beneficial effects observed in this model." | 1.35 | Beneficial effects of rolipram in the R6/2 mouse model of Huntington's disease. ( Bernardi, G; DeMarch, Z; Fusco, FR; Giampà, C; Patassini, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giampà, C | 4 |
| Middei, S | 1 |
| Patassini, S | 3 |
| Borreca, A | 1 |
| Marullo, F | 1 |
| Laurenti, D | 2 |
| Bernardi, G | 4 |
| Ammassari-Teule, M | 1 |
| Fusco, FR | 4 |
| Giralt, A | 1 |
| Saavedra, A | 1 |
| Carretón, O | 1 |
| Xifró, X | 1 |
| Alberch, J | 1 |
| Pérez-Navarro, E | 1 |
| Jin, YN | 1 |
| Hwang, WY | 1 |
| Jo, C | 1 |
| Johnson, GV | 1 |
| Anzilotti, S | 1 |
| Dato, C | 1 |
| Leuti, A | 1 |
| Colucci D'Amato, L | 1 |
| Perrone, L | 1 |
| Melone, MA | 1 |
| DeMarch, Z | 2 |
| Martorana, A | 1 |
6 other studies available for rolipram and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Phosphodiesterase type IV inhibition prevents sequestration of CREB binding protein, protects striatal parvalbumin interneurons and rescues motor deficits in the R6/2 mouse model of Huntington's disease.
Topics: Analysis of Variance; Animals; Corpus Striatum; CREB-Binding Protein; Disease Models, Animal; Explor | 2009 |
Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease.
Topics: Animals; Calcineurin; Cognition Disorders; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide P | 2011 |
Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.
Topics: Anilides; Animals; Blotting, Western; Cell Line; Cells, Cultured; Glucose; Huntington Disease; Hydro | 2012 |
Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition.
Topics: Animals; Disease Models, Animal; Huntington Disease; Male; MAP Kinase Signaling System; Mice; Mice, | 2012 |
Beneficial effects of rolipram in a quinolinic acid model of striatal excitotoxicity.
Topics: Animals; Cell Survival; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Disease Models | 2007 |
Beneficial effects of rolipram in the R6/2 mouse model of Huntington's disease.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Dise | 2008 |