Page last updated: 2024-11-04

rolipram and Adrenoleukodystrophy

rolipram has been researched along with Adrenoleukodystrophy in 2 studies

Adrenoleukodystrophy: An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS).

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pahan, K1
Khan, M1
Singh, I1
Netik, A1
Hobel, A1
Rauschka, H1
Molzer, B1
Forss-Petter, S1
Berger, J1

Other Studies

2 other studies available for rolipram and Adrenoleukodystrophy

ArticleYear
Therapy for X-adrenoleukodystrophy: normalization of very long chain fatty acids and inhibition of induction of cytokines by cAMP.
    Journal of lipid research, 1998, Volume: 39, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenoleukodystrophy; Animals; Astrocytes; Colforsin; Cyclic

1998
Rolipram does not normalize very long-chain fatty acid levels in adrenoleukodystrophy protein-deficient fibroblasts and mice.
    Journal of inherited metabolic disease, 2000, Volume: 23, Issue:6

    Topics: Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding

2000