rolipram has been researched along with Acute Confusional Senile Dementia in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rolipram attenuated cognitive decline as well as anxiety- and depression-like behaviors." | 8.31 | Rolipram Ameliorates Memory Deficits and Depression-Like Behavior in APP/PS1/tau Triple Transgenic Mice: Involvement of Neuroinflammation and Apoptosis via cAMP Signaling. ( Cong, YF; Hou, XQ; Liu, D; Liu, FW; Shen, XR; Song, SS; Xu, L; Zhang, HT, 2023) |
| "Rolipram attenuated cognitive decline as well as anxiety- and depression-like behaviors." | 4.31 | Rolipram Ameliorates Memory Deficits and Depression-Like Behavior in APP/PS1/tau Triple Transgenic Mice: Involvement of Neuroinflammation and Apoptosis via cAMP Signaling. ( Cong, YF; Hou, XQ; Liu, D; Liu, FW; Shen, XR; Song, SS; Xu, L; Zhang, HT, 2023) |
| "Rolipram treatment significantly attenuated STZ induced and age related memory deficits, biochemical and histopathological alterations." | 1.46 | Inhibitor of Phosphodiestearse-4 improves memory deficits, oxidative stress, neuroinflammation and neuropathological alterations in mouse models of dementia of Alzheimer's Type. ( Kumar, A; Singh, N, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 4 (30.77) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Wang, Y | 1 |
| Wang, B | 1 |
| Li, W | 1 |
| Huang, L | 3 |
| Li, X | 3 |
| Wu, Y | 1 |
| Li, Z | 2 |
| Huang, YY | 1 |
| Wu, D | 1 |
| Luo, HB | 1 |
| Hu, J | 2 |
| Pan, T | 2 |
| An, B | 1 |
| Xie, S | 1 |
| Zhou, Y | 1 |
| Luo, H | 1 |
| Xi, M | 1 |
| Sun, T | 1 |
| Chai, S | 1 |
| Xie, M | 1 |
| Chen, S | 1 |
| Deng, L | 1 |
| Du, K | 1 |
| Shen, R | 1 |
| Sun, H | 1 |
| Liu, J | 1 |
| Liu, L | 1 |
| Zheng, L | 1 |
| Feng, KW | 1 |
| Wang, HT | 1 |
| Xu, JP | 2 |
| Zhou, ZZ | 1 |
| Cong, YF | 1 |
| Liu, FW | 1 |
| Xu, L | 1 |
| Song, SS | 1 |
| Shen, XR | 1 |
| Liu, D | 1 |
| Hou, XQ | 1 |
| Zhang, HT | 2 |
| Ahmad, F | 1 |
| Jing, Y | 1 |
| Lladó, A | 1 |
| Liu, P | 1 |
| Kumar, A | 1 |
| Singh, N | 1 |
| Cheng, YF | 1 |
| Wang, C | 1 |
| Lin, HB | 1 |
| Li, YF | 1 |
| Huang, Y | 1 |
| Gong, B | 1 |
| Vitolo, OV | 1 |
| Trinchese, F | 1 |
| Liu, S | 1 |
| Shelanski, M | 1 |
| Arancio, O | 1 |
| Comery, TA | 1 |
| Martone, RL | 1 |
| Aschmies, S | 1 |
| Atchison, KP | 1 |
| Diamantidis, G | 1 |
| Gong, X | 1 |
| Zhou, H | 1 |
| Kreft, AF | 1 |
| Pangalos, MN | 1 |
| Sonnenberg-Reines, J | 1 |
| Jacobsen, JS | 1 |
| Marquis, KL | 1 |
| Costa, DA | 1 |
| Cracchiolo, JR | 1 |
| Bachstetter, AD | 1 |
| Hughes, TF | 1 |
| Bales, KR | 1 |
| Paul, SM | 1 |
| Mervis, RF | 1 |
| Arendash, GW | 1 |
| Potter, H | 1 |
2 reviews available for rolipram and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Novel Phosphodiesterase Inhibitors for Cognitive Improvement in Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Cognition; Humans; Phosphodiesterase Inhibitors | 2018 |
Therapeutic potential of phosphodiesterase inhibitors for cognitive amelioration in Alzheimer's disease.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alzheimer Disease; Animals; Cognition; Cyclic GMP; Phosphodiest | 2022 |
11 other studies available for rolipram and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Benzofurans; Clioquinol; Cognition; | 2015 |
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiester | 2019 |
Dual functional cholinesterase and PDE4D inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of tacrine-pyrazolo[3,4-b]pyridine hybrids.
Topics: Alzheimer Disease; Cholinesterases; Humans; Molecular Structure; Phosphodiesterase Inhibitors; Pyrid | 2019 |
Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Donepezil; Drug Design; | 2022 |
Rolipram Ameliorates Memory Deficits and Depression-Like Behavior in APP/PS1/tau Triple Transgenic Mice: Involvement of Neuroinflammation and Apoptosis via cAMP Signaling.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apoptosis; Depres | 2023 |
Chemical Stimulation of Rodent and Human Cortical Synaptosomes: Implications in Neurodegeneration.
Topics: Actins; Aged; Alzheimer Disease; Animals; Brain; Colforsin; Female; Frontal Lobe; Humans; Long-Term | 2021 |
Inhibitor of Phosphodiestearse-4 improves memory deficits, oxidative stress, neuroinflammation and neuropathological alterations in mouse models of dementia of Alzheimer's Type.
Topics: Acetylcholinesterase; Aging; Alzheimer Disease; Animals; Antioxidants; Brain; Cholinesterase Inhibit | 2017 |
Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Cyclic AMP; Cyclic AMP Respon | 2010 |
Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cognition; Cyclic AMP Response Element-B | 2004 |
Acute gamma-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-P | 2005 |
Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; | 2007 |