Page last updated: 2024-11-04

rofecoxib and Venous Thrombosis

rofecoxib has been researched along with Venous Thrombosis in 4 studies

Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.

Research Excerpts

ExcerptRelevanceReference
"The potential prothrombotic effect of the cyclooxygenase-2 (COX-2) inhibitor Rofecoxib (Vioxx) was investigated using murine thrombosis models."7.74Prothrombotic effect of Rofecoxib in a murine venous thrombosis model. ( Gallacher, DJ; Hoylaerts, MF; Lijnen, HR; Lu, HR; Nagai, N, 2008)
"The potential prothrombotic effect of the cyclooxygenase-2 (COX-2) inhibitor Rofecoxib (Vioxx) was investigated using murine thrombosis models."3.74Prothrombotic effect of Rofecoxib in a murine venous thrombosis model. ( Gallacher, DJ; Hoylaerts, MF; Lijnen, HR; Lu, HR; Nagai, N, 2008)
"MNA, however, did not affect venous thrombosis."1.341-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway. ( Adamus, J; Bartus, M; Buczko, W; Chlopicki, S; Gebicki, J; Lomnicka, M; Mogielnicki, A; Swies, J, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagai, N1
Hoylaerts, MF1
Gallacher, DJ1
Lu, HR1
Lijnen, HR1
Chlopicki, S1
Swies, J1
Mogielnicki, A1
Buczko, W1
Bartus, M1
Lomnicka, M1
Adamus, J1
Gebicki, J1
Cleland, LG1
James, MJ1
Stamp, LK1
Penglis, PS1
Fenn, CG1

Reviews

1 review available for rofecoxib and Venous Thrombosis

ArticleYear
COX-2 inhibition and thrombotic tendency: a need for surveillance.
    The Medical journal of Australia, 2001, Aug-20, Volume: 175, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Celecoxib; Cyclooxygenase I

2001

Other Studies

3 other studies available for rofecoxib and Venous Thrombosis

ArticleYear
Prothrombotic effect of Rofecoxib in a murine venous thrombosis model.
    Thrombosis research, 2008, Volume: 122, Issue:5

    Topics: Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Femoral Artery; Jugular Veins; Lactone

2008
1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway.
    British journal of pharmacology, 2007, Volume: 152, Issue:2

    Topics: Animals; Aorta; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Epoprostenol; Fibrinolytic Agents; Hy

2007
COX-2 inhibition and thrombotic tendency.
    The Medical journal of Australia, 2002, Jan-21, Volume: 176, Issue:2

    Topics: Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Myocardial Infarction; Pyrazoles; Sulfonamid

2002