rofecoxib has been researched along with Stevens-Johnson Syndrome in 3 studies
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of rofecoxib (Vioxx)-associated Stevens-Johnson syndrome with corneal and conjunctival changes." | 7.72 | A case of rofecoxib-associated stevens-johnson syndrome with corneal and conjunctival changes. ( Abelson, M; Barazi, M; Butrus, S; Goldberg, D; Panigrahi, D, 2004) |
| "The objective of this study is to review cases of Stevens-Johnson syndrome and toxic epidermal necrolysis reported to the FDA associated with the use of the selective COX-2 inhibitor NSAIDs celecoxib, rofecoxib and valdecoxib, and to compare reporting rates of the two conditions associated with these drugs to each other, meloxicam (an oxicam NSAID that came on the US market at a similar time) and the background incidence rate." | 3.73 | Comparison of reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis in association with selective COX-2 inhibitors. ( Bonnel, R; Brinker, A; Governale, L; Karwoski, C; La Grenade, L; Lee, L; Weaver, J, 2005) |
| "To report a case of rofecoxib (Vioxx)-associated Stevens-Johnson syndrome with corneal and conjunctival changes." | 3.72 | A case of rofecoxib-associated stevens-johnson syndrome with corneal and conjunctival changes. ( Abelson, M; Barazi, M; Butrus, S; Goldberg, D; Panigrahi, D, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldberg, D | 1 |
| Panigrahi, D | 1 |
| Barazi, M | 1 |
| Abelson, M | 1 |
| Butrus, S | 1 |
| La Grenade, L | 1 |
| Lee, L | 1 |
| Weaver, J | 1 |
| Bonnel, R | 1 |
| Karwoski, C | 1 |
| Governale, L | 1 |
| Brinker, A | 1 |
| Layton, D | 1 |
| Marshall, V | 1 |
| Boshier, A | 1 |
| Friedmann, P | 1 |
| Shakir, SA | 1 |
3 other studies available for rofecoxib and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
A case of rofecoxib-associated stevens-johnson syndrome with corneal and conjunctival changes.
Topics: Arthralgia; Conjunctiva; Cornea; Cyclooxygenase Inhibitors; Female; Humans; Lactones; Middle Aged; S | 2004 |
Comparison of reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis in association with selective COX-2 inhibitors.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Celecoxib; Cycl | 2005 |
Serious skin reactions and selective COX-2 inhibitors: a case series from prescription-event monitoring in England.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Celecoxib; Cyclooxygenase 2 | 2006 |