rofecoxib has been researched along with Reperfusion Injury in 7 studies
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac adverse effects are among the leading causes of the discontinuation of clinical trials and the withdrawal of drugs from the market." | 5.56 | Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion. ( Baczkó, I; Baranyai, T; Brenner, GB; Ferdinandy, P; Gergely, TG; Giricz, Z; Görbe, A; Husti, Z; Kiss, B; Lázár, B; Makkos, A; Nagy, CT; Onódi, Z; Sághy, É; Sayour, NV; Schulz, R; Tóthfalusi, L; Varga, RS; Varró, A; Zádori, ZS, 2020) |
| "Cardiac adverse effects are among the leading causes of the discontinuation of clinical trials and the withdrawal of drugs from the market." | 1.56 | Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion. ( Baczkó, I; Baranyai, T; Brenner, GB; Ferdinandy, P; Gergely, TG; Giricz, Z; Görbe, A; Husti, Z; Kiss, B; Lázár, B; Makkos, A; Nagy, CT; Onódi, Z; Sághy, É; Sayour, NV; Schulz, R; Tóthfalusi, L; Varga, RS; Varró, A; Zádori, ZS, 2020) |
| "Indomethacin treatment induced a better renal function (serum urea) when compared to control animals at 24, 48 and 72 h (219+/-54." | 1.33 | Cyclooxygenase 1 and/or 2 blockade ameliorates the renal tissue damage triggered by ischemia and reperfusion injury. ( Câmara, NO; Cenedeze, MA; Feitoza, CQ; Gonçalves, GM; Pacheco-Silva, A; Pinheiro, HS; Santos, OF, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Brenner, GB | 1 |
| Makkos, A | 1 |
| Nagy, CT | 1 |
| Onódi, Z | 1 |
| Sayour, NV | 1 |
| Gergely, TG | 1 |
| Kiss, B | 1 |
| Görbe, A | 1 |
| Sághy, É | 1 |
| Zádori, ZS | 1 |
| Lázár, B | 1 |
| Baranyai, T | 1 |
| Varga, RS | 1 |
| Husti, Z | 1 |
| Varró, A | 1 |
| Tóthfalusi, L | 1 |
| Schulz, R | 1 |
| Baczkó, I | 1 |
| Giricz, Z | 1 |
| Ferdinandy, P | 1 |
| Nakagiri, A | 1 |
| Murakami, M | 1 |
| Bhardwaj, A | 1 |
| Batchu, SN | 1 |
| Kaur, J | 1 |
| Huang, Z | 1 |
| Seubert, JM | 1 |
| Knaus, EE | 1 |
| Brzozowski, T | 3 |
| Konturek, PC | 3 |
| Konturek, SJ | 3 |
| Pajdo, R | 3 |
| Kwiecien, S | 2 |
| Pawlik, M | 2 |
| Drozdowicz, D | 3 |
| Sliwowski, Z | 3 |
| Pawlik, WW | 1 |
| Feitoza, CQ | 1 |
| Câmara, NO | 1 |
| Pinheiro, HS | 1 |
| Gonçalves, GM | 1 |
| Cenedeze, MA | 1 |
| Pacheco-Silva, A | 1 |
| Santos, OF | 1 |
| Stachura, J | 1 |
| Hahn, EG | 2 |
| Ptak, A | 1 |
7 other studies available for rofecoxib and Reperfusion Injury
| Article | Year |
|---|---|
Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Cardiotoxicity; Cell Survival; | 2020 |
Roles of NADPH oxidase in occurrence of gastric damage and expression of cyclooxygenase-2 during ischemia/reperfusion in rat stomachs.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Gastric M | 2009 |
Cardiovascular properties of a nitric oxide releasing rofecoxib analogue: beneficial anti-hypertensive activity and enhanced recovery in an ischemic reperfusion injury model.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 2; Disease Models, Animal; Drug Des | 2012 |
Ischemic preconditioning of remote organs attenuates gastric ischemia-reperfusion injury through involvement of prostaglandins and sensory nerves.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygen | 2004 |
Cyclooxygenase 1 and/or 2 blockade ameliorates the renal tissue damage triggered by ischemia and reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase | 2005 |
Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia-reperfusion-induced gastric lesions.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 1999 |
Ischemic preconditioning, the most effective gastroprotective intervention: involvement of prostaglandins, nitric oxide, adenosine and sensory nerves.
Topics: Adenosine; Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; | 2001 |