rofecoxib has been researched along with Pancreatic Neoplasms in 2 studies
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rofecoxib (30 mg/kg) was administered orally to animals every day for eight weeks." | 1.32 | [Effects of rofecoxib on angiogenesis of pancreatic cancer xenograft in nude mice]. ( Liu, CL; Tang, CW; Wang, CH; Zhou, XC, 2004) |
| "PANC-1 and MIAPaCa-2 pancreatic cancer cells were treated with PGE(2) or rofecoxib, a selective COX-2 inhibitor." | 1.32 | Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2. ( Ashley, SW; Benoit, E; Clancy, TE; Duxbury, M; Ito, H; Whang, EE; Zinner, MJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, XC | 1 |
| Tang, CW | 1 |
| Liu, CL | 1 |
| Wang, CH | 1 |
| Ito, H | 1 |
| Duxbury, M | 1 |
| Benoit, E | 1 |
| Clancy, TE | 1 |
| Zinner, MJ | 1 |
| Ashley, SW | 1 |
| Whang, EE | 1 |
2 other studies available for rofecoxib and Pancreatic Neoplasms
| Article | Year |
|---|---|
[Effects of rofecoxib on angiogenesis of pancreatic cancer xenograft in nude mice].
Topics: Animals; Cyclooxygenase Inhibitors; Humans; Lactones; Male; Matrix Metalloproteinase 2; Matrix Metal | 2004 |
Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2.
Topics: Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Extracellular Sig | 2004 |